Essential for women of child-bearing age!
Important: Folate supplementation must be started before pregnancy. The damage from folate deficiency is done to the developing foetus at 3 weeks from conception. Some women are not even aware of the pregnancy at this stage, so all women who may become pregnant should take supplemental folate!
- Science-Based Nutrition
- Dietary Supplement
- Suitable for all women, pregnant or of childbearing age
Functional deficiencies of the essential nutrient folate (folic acid) are common, and can impair key life processes including gene-level regulation, cell growth patterns and tissue repair, from before birth through old age. Best Fully Active Folate provides MTHF (6S)-5-methyltetrahydrofolate, the folate form most directly required for DNA regulation and other fundamental metabolic processes. Vitamin C is included for added stability.
A nutrient naturally built into the body's chemistry.
- Identical to the body's most highly active folate form
- Helps correct inherited and lifestyle-related folate deficiencies
- Supports healthy mood, memory, circulation, and well-being
Up to half the population has a genetic defect called MTHFR gene polymorphism, which prevents activation of folic acid. A MTHFR Gene Test can determine if you carry this faulty gene and are unable to convert folic acid into its active MTHFR form. Symptoms can include weight gain, fatigue and depression. This can be treated by using folinic acid, which removes some steps in the conversion, or better still, this active form, also known as 5-MTHF or (6S)-5-Methyltetrahydrofolic acid, the natural active form of folic acid that does not require any further conversion in the body.
Beware of other products which do not specify the (6S)-5 prefix - they are not the same, and may give unpredictable results.
Methyltetrahydrofolate reductase (MTHFR) is a critical part of the methylation pathway required for every cell in the body, acting as a switch, turning on or off various biological activities.
Methylation is an essential metabolic signaling process for detoxification, histamine tolerance, stress management, DNA and RNA protection and repair, neurotransmitter myelination (nerve protection).
Disruptions of MTHFR can increase risk of cancer.
The two genes most commonly associated with increased cancer risk are polymorphisms C677T and A1298C. Natural methylation pathways can be improved by detoxing, stress management, adequate sleep, reducing toxin exposure, fruits and vegetables, and natural folate sources such as dark leafy greens and lentils.
The best methylation is to also use
TMG (Trimethylglycine) which has three methyl groups attached to each glycine molecule, and can easily donate methyl groups as the body needs. Read more in my TMG article.
Recent studies also reveal that taking conventional folic acid supplements can actually INCREASE the un-methylated folic acid in the blood, increasing cancer and other health risks.
A recent study from the University of Georgia and Tufts University found that folate can stimulate stem cell proliferation in the body. Stem cells can help rebuild damaged body parts.
Take one veggie capsule per day with water.
Serving Size 1 Veggie Capsule
||Amount Per Serving
||% Daily Value
|Folate (as Quatrefolic®
[6S]-5-methyltetrahydrofolic acid equivalent to 800 mcg of [6S]-5-methyltetrahydrofolic acid, glucosamine salt)
*Daily Value not established.
Quatrefolic® is a registered trademark of Gnosis S.p.A. Corporation.
Brown rice flour, hypromellose (vegetable capsule), may contain one or both of the following: magnesium stearate, silica
Manufacture date: June 2016, suggested expiry June 2019
Normally stocked in South Australia. The system will only allow orders to be placed when local stock is available.
When in stock, will express post same or next business day to any Australian address.
If sold out, please advise your desired quantity and allow up to 14 days for delivery.
LeanMachine does not post to destinations outside of Australia.
We normally use Australia Post express satchels with tracking, except for some very heavy or large items. Orders over 3kg may be sent regular satchels instead of express.
All products are in sealed packaging and shipped in bubble-wrap for protection against damage and temperature extremes.
LeanMachine supplies only supplements from reputable suppliers.
Trust LeanMachine: Our selected products are high-quality, mostly made in USA, all offering excellent value and have a valid expiry date.
Unlike many suppliers, we are not committed to any particular brand.
Made in USA. Some components may be made by Gnosis S.p.A. Corporation in Italy.
Questions, comments, problems
Email firstname.lastname@example.org or call 0408 816416 for personal assistance.
Because of constraints imposed on all by the TGA (Australian Therapeutic Goods Administration), LeanMachine does not claim that any supplement will diagnose, prevent, treat or cure any disease, sickness, condition or ailment.
Any advice or information given here is of a general nature and everyone should discuss their individual nutritional needs with their health professional.
LeanMachine cannot take responsibility for any undesirable outcome from using any product, as we have no control over individual health, use, mis-use, sensitivity, suitability or interactions with prescription medication.