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Auti-Immune conditions are becoming more common, when they were almost unheard of just decades ago. Poor Vitamin D3 and poor nutrition are the two main causes.

 
Posted by: | Posted on: November 3, 2019

Vitamin D3

Written by Brenton Wight – LeanMachine, Health Researcher.

Health Facts on Vitamin D3 – the Natural Cure for all disease!

Why do we need Vitamin D3?
First, to help absorb calcium and build strong bones with the help of vitamin K2.
Second, to build the immune system, in conjunction with gut bacteria – the other half of the immune system story.
Depending on which study we believe, optimal vitamin D3 can prevent between 50% and 90% of all cancers, as well as Multiple Sclerosis, and reduce the intensity or even cure almost every other disease.
If a drug company developed something that would do this, it would make headlines around the world and win a Nobel prize, and many billions of dollars would be saved in the health care budgets of countries everywhere.
If the entire population had optimal Vitamin D3 combined with a healthy diet, countless lives would be saved from cancer, many illnesses would disappear, most artificial replacements of hips and knees would not be required, thousands of people clogging up the nursing homes in their wheelchairs would be out playing tennis and leading active, productive lives.
Have I convinced you yet that just a few dollars for a year’s supply of super-strength 5000 IU Vitamin D3 would be a good investment in your future?
If not, then perhaps you should go and reserve that spot in the nursing home, and pick out the burial plot while you’re at it!

Benefits of Vitamin D3

Studies show that Vitamin D3 has cancer inhibiting properties, especially breast, prostate, pancreas, colon, skin cancer and leukaemia.
While millions are spent trying to find a cure for cancer, Vitamin D3 could be used to prevent cancer in the first place, at a cost equivalent to a drop in the ocean.
Vitamin D3 deficiencies can cause the following:
Colds and flu
Vitamin D3 helps prevent or reduce severity of colds, flu, and almost every other infection. LeanMachine is living proof. After 10 years of taking Vitamin D3, no colds, no flu, no infections of any kind, not even a headache!
When we look at studies funded by drug companies who manufacture vaccinations, which are always biased in favour of the flu shot, the NNT (Number Needed to Treat) for the flu vaccine is 40, meaning that to protect one person from getting the flu, 40 people must receive the vaccination. Compare this with Vitamin D3, where the NNT is 33 in the average population, and in those people with D3 deficiency, the NNT drops to 4. In other words, for the average person, D3 is significantly better than the flu shot, and for those with low Vitamin D3, D3 supplements work 10 time better than the flu shot!
Most infections are naturally destroyed by our own immune system, mainly the T-cells, but T-cells need Vitamin D3 to operate correctly.
Studies funded privately, without the influence of the drug companies, have foud the flu shot to be even less effective, with those over the age of 65, or under the age of 2, or those on statin medications, all receiving NO statistically discernible benefit from the flu shot, and everyone else receiving a very marginal benefit such as a reduction in duration of illness of about 1 day.
On the downside, those taking the flu shot every year received less benefit (less protection), and actually INCREASED risk of coming down with a different strain of the flu!
More on vaccinations under the heading below.

OA (Osteoarthritis)
Osteoarthritis (OA)is the most common disease in people over age 50, more common than the common cold, and especially in women.
OA is directly linked to Vitamin D3 deficiency, and higher Vitamin D3 levels lower the risk.
Studies show that hip fractures in high risk population groups can be reduced by up to 40% by supplementing with Vitamin D3.
Partly because bones are stronger, and partly because people with good Vitamin D3 levels have much better balance and stronger muscles, so don’t fall over as much.

RA (rheumatoid arthritis) and MS (Multiple Sclerosis) appear to have the same link.

Obesity
Most Australians (two thirds) and others in Western society are overweight or obese.
Two thirds of people in Western society are also deficient in Vitamin D3, and this is no coincidence; there is a direct link between Vitamin D3 deficiency and obesity.
On average, the more Vitamin D3 deficient a person is, the more obese they are.
Healthy levels of Vitamin D3 are seen mainly in lean, healthy people.

Chronic pain
Chronic pain from any source can be reduced with Vitamin D3, even a simple headache, migraine, back pain, fibromyalgia, etc.
Many people with osteoporosis have chronic pain, typically lower back pain, often a sign of D3 deficiency.
Those people usually exercise less because of the pain, and insufficient exercise causes depression, worsens their osteoporosis, increases obesity, and their condition only gets worse.

Cancer
Cancer is a devastating condition, but high levels of Vitamin D3 offer up to 80% or more protection, especially childhood cancers, breast, prostate, pancreas, skin and colon cancer.
A recent study confirmed that women with high levels of Vitamin D3 had about 85% reduced risk of breast cancer compared to those with the lowest levels of Vitamin D3.
Vitamin D3 is critical to the body’s production of GcMAF, a cancer-fighting protein that inhibits cancer metastasis, and is capable of reversing the devastating effects of cancer on the body. Vitamin D3 supports GcMAF synthesis, helping to shut down pro-cancer receptors and enzymes that encourage metastasis.
Vitamin D3 binding protein-macrophage activating factor is another protein reducing cancerous activity, which directly stimulates the immune response by suppressing angiogenesis (blood vessel growth) required for cancer cell migration and tumor growth. DBP-maf requires Vitamin D3 for transport in the bloodstream.

Depression
There are links between low levels of Vitamin D3 and depression.
For depression sufferers, LeanMachine recommends extra Vitamin D3 from sunlight because getting outside in the sun always lifts our mood. If we cannot get out in the sun, supplementation is a must.

Hearing Loss
Vitamin D3 deficiency weakens our bones, but when the three tiny bones (hammer, anvil and stirrup) in the ear become weak and spongy, attenuation of sound transmission results in hearing loss.

Allergies
Recent studies show that children with allergies have a high chance of being deficient in Vitamin D3, and those with the worst allergies, are over 80% likely to be deficient in vitamin D3.

Heart disease
The number one killer of Western society people is still cardiac disease.
Vitamin D3 deficiencies bring on high blood pressure, stroke and heart attack.
Number two is cancer, so we can alleviate both killers easily by eating a healthy diet and getting enough Vitamin D3 from sunlight and/or supplements.

Type 1 diabetes
Pregnant women who are deficient in Vitamin D3 are far more likely to produce offspring with Type 1 diabetes.
Any child deprived of sunlight in the first few years of life also has a far higher risk of type 1 Diabetes.
How do we get Vitamin D3?
We get Vitamin D3 from the sun, but we need tha basic building-blocks in the body first.
The normal process of Vitamin D3 metabolism can be stopped by the deficiency of one single nutrient, a healthy, nutrient-rich diet is essential.
In particular, we need cholesterol, which has been demonised for decades. More on this later.
Vitamin K2 – No Bones without it
Some people say we need Calcium for strong bones, but we get plenty of calcium from the diet, and we can absorb calcium with no problems as long as we have enough Vitamin D3.
No vitamin D3 means no calcium absorption, so adding more calcium to the diet without vitamin D3 means potential for calcium to form as plaque in our arteries, kidneys or other places where it will only damage the body.
Vitamin K2, which comes from animal products such as chicken, cheese, butter, eggs, etc, can help build bones by directing calcium to bones and teeth where it belongs, and helps keep our arteries, kidneys and other organs free from calcium.
The only vegetable source of K2 is Natto (fermented soy), which explains why Japanese post-menopausal women have much stronger bones than Western women, as Natto is part of the traditional Japanese diet.
Vitamin K2 is not to be confused with Vitamin K (or K1), which is required for effective blood clotting, but not as effective as K2 for bones, but still desirable in the diet.
K1 comes from intestinal bacteria as well as from green leafy vegetables like kale, spring onions, brussels sprouts, cabbage, broccoli, basil, asparagus, also prunes.
For vegetarians or vegans, supplementation of Vitamin K2 is essential as well as D3 for healthy bones. Vitamin D3 metabolism is complex, where each essential and critical nutrient provides the path to the next step, and one missing link in the chain will stop the entire process.
So it is no surprise that a third of our population is deficient in Vitamin D3, and around 90% are less than optimal. Unfortunately, these are the people who are at the highest risk of cancer.
Importance of Diet
Vitamin D3 cannot form without basic nutrients for the multi-stage process and this explains why so many people are deficient.
D3 – A Vitamin or a Hormone?
The answer is both.
It is a hormone (a chemical messenger) because it controls cells, organs, muscle and bone in everyday function, and because the body can manufacture it with sunlight exposure on skin.
It is a vitamin because it binds calcium so we can absorb it, as we humans cannot digest calcium without Vitamin D3, which maintains calcium and phosphate concentrations in the blood, providing minerals for bones, nerves, muscles, immune function, and lowers inflammation.
Many cell functions are controlled in part by vitamin D3, aiding in weight loss, blood glucose regulation, metabolism, and essential fatty acids (Omega-3) processing.
There is no point taking calcium or omega-3 foods or supplements without a good supply of Vitamin D3.
Almost every cell in the body has Vitamin D3 receptors, so Vitamin D3 is a crucial nutrient.
Vitamin D, D2 or D3?
The terms Vitamin D and vitamin D3 are used interchangeably here. D3 is the correct and natural Vitamin D.
D3 exists in the body as the storage form 25(OH) and the active form 1,25 2(OH). Vitamin D2 (ergocalciferol) is an artificial version of Vitamin D3 (cholecalciferol), or vitamin D coming from some foods.
D2 has very low affinity for DBP (vitamin D binding protein) so it cannot be easily stored and should never be used.
Firstly, D2 has nowhere near the healthy properties of D3 (cholecalciferol), and secondly, D2 tends to block absorption of the real D3.
Many foods come “fortified with vitamin D” but this is invariably an artificial D2 with poor benefits.
Some early medical studies on vitamin D used inferior synthetic D2 which is toxic at much lower doses, and unfairly discredited the real D3 which was not even being used in the studies.
How is Vitamin D3 made?
We get vitamin D3 from sunlight, food or supplements.
D3 from sunlight
Most people know we get Vitamin D3 from sunlight, but there is a multi-stage process involved.
Production starts in the liver, which makes 7-dehydrocholesterol, which then migrates to the skin to be altered by UVB (ultra-violet light in the B range) to become pre-vitamin D3.
This is carried back to the liver to be mediated by an enzyme (25-hydroxylase) to become 25-hydroxyvitamin D, where a hydroxy (OH) molecule is added to build the storage form 25(OH).
This is then transported to the kidneys to be mediated by yet another enzyme (1-alpha-hydroxylase) to finally become calcitriol, where a second hydroxy (OH) is added. This is the active form of vitamin D3, also known as cholecalciferol or 1,25 dihydroxyvitaminD3 or the active form 1,25 2(OH). Dihydroxy means that the D3 molecule has two OH molecules added, one from the liver and a second from the kidneys.
Vitamin D3 is carried in the blood by DBP (vitamin D-binding protein).
This entire process takes around 15 days, so if we shower every day, we “wash off” most of the pre-vitamin D, so morning showers are best, allowing the pre-vitamin D to start the migration back to the liver before the next shower.
And a day at the beach won’t help our vitamin D3 if we go for a swim, and worse if we get sunburnt!
Statins rob our Vitamin D3
As we age, we lose the ability to synthesise vitamin D from sunlight, and those on statin medication (half the aged population) cannot make 7-dehydrocholesterol, co-enzyme Q10, Cholesterol Sulfate and other important requirements for the body, because when statins slow the liver production of cholesterol, all of the above are affected.
No one should ever take a statin drug (Lipitor, Crestor, Simvastatin and others) other than exceptional circumstances, as they generally do much more harm than good.
Independent studies show that while some deaths from heart disease are reduced, deaths from all other causes is INCREASED by statin medication!
Also as we age, we generate less stomach acid, losing the ability to take in B12, Methyl Folate (never Folic Acid!), vitamin K2 and other nutrients that vitamin D requires to do it’s job. If we get reflux or heartburn, doctors normally prescribe Nexium or antacids, which may relieve symptoms short-term, but only make the problem worse. The best way to cure heartburn is to eat less, and eat an alkaline-forming diet, but that is another story in my Alkaline Diet article.
Those who dress fully covered for cultural reasons or those with dark skin always need more vitamin D.
Annual blood tests for vitamin D3 are advisable if taken at very high doses as excess levels can become toxic.
For adults, toxic levels for vitamin D3 are generally not seen unless we take in some 40,000 IU daily for many weeks.
Vitamin A can also be toxic in high levels, but if A and D are taken together, the toxic levels are some 5 times higher for both A and D, giving a huge margin of safety, so old “toxic levels” should really be called “imbalance levels”.
Another factor is Vitamin K2, discussed later.

Other things that Steal our Vitamin D3
Being overweight – the more overweight we are, the less bioavailable D3 becomes. But if we take D3 supplements or get more sunshine, this will assist our weight-loss efforts!
Being old – as we age, our ability to absorb D3 from sunlight and from food reduces, so supplementation becomes more essential
BPA (Bisphenol A)
BPA and other endocrine-disrupting chemicals reduce our Vitamin D3 levels. Avoid foods in plastic or cans and use glass containers.
Liver problems
A poor liver produces less bile, which reduces absorption of Vitamin D3. Look after the liver – avoid excess alcohol and eat a healthy diet of quality fats, few carbohydrates, and low to moderate protein.
Kidney problems
As kidney disease gets worse, so do D3 levels. Look after kidneys by drinking plenty of clean water and eating a healthy diet
Gut bacteria
These 100 trillion organisms are a major component of our immune system, and also aid in absorption and processing of minerals and vitamins, including D3. People with celiac disease, chronic pancreatitis, IBS (irritable bowel syndrome) or Crohn’s disease, or those taking antibiotics, will all have reduced D3, so essential supplements are D3 and probiotics
Slip, Slop, Slap in the face campaign
This disastrous campaign has been running for over 30 years in Australia, costing the taxpayer many millions of dollars, and has caused many more millions in extra health care, more disease, and many more lives lost.
True, reduced sunlight has reduced the number of mostly harmless skin cancers such as basal cell carcinoma and squamous cell carcinoma which are easily treated, and rarely turn into something more serious (less than 1% of cases).
But the number of MELANOMA cancers – the real, deadly kind, has DOUBLED, but this fact has been hidden by the Australian Cancer Council who are behind the Slip, Slop, Slap campaign! The primary reason, of course, is lack of vitamin D3 due to reduced sunlight, reducing immunity.
Melanomas also appear on the soles of feet, under arms and other places where sunlight is very limited, but so-called “specialists” still blame the sun!
The science cannot be denied. The closer one lives to the Equator, the less chance of any type of cancer, a proven fact.

Too much sunlight?
If we get D3 from sunlight, then surely if we spend all day in the sun, like construction workers and other outdoor activities, we should get plenty?
Wrong. After we spend around 10 to 20 minutes in the sun in the middle of the day (90 minutes for dark-skinned people), we reach a point where the body will no longer synthesise any more vitamin D3.
This is the way the body is designed to prevent toxic levels from building up, and also the reason why we get a tan – to prevent too much vitamin D3 from the sun.
If our skin starts to get the slightest shade of pink, it is time to cover up or seek some shade, as more sun will only then cause damage, with no extra vitamin D3 past that point.
And if we get a healthy dose of sunlight one day, we can happily work inside the next day, as it may take 2 days to build new skin resources for more absorption.

The Morning Myth
The cancer society and other “health” organisations all say the we should avoid the sun in the middle of the day, and only go out in the morning or the evening when the sun is low in the sky. Wrong again!
This is actually the complete reverse of the truth!
The sun produces ultra-violet rays in three bandwidths, named UV-A, UV-B and UV-C, each with different properties.
UV-A
We get UV-A from all sunlight, no matter what time of day, and it passes through cloud and glass, and this kind travels deeper into the skin, causes skin damage and ZERO vitamin D production.
We can sit by a window or in a car with windows up, on a hot sunny day and never get any vitamin D.
We can be outside all day when there is cloud cover, but we will never get any vitamin D.
All we get from UV-A is skin damage.
UV-B
We get UV-B ONLY from a clear blue sky, and ONLY when the sun is HIGH in the sky. This is the “good” sunlight, as this is the ONLY kind that gives us vitamin D.
When the sun is lower in the sky, most UV-B is absorbed in the atmosphere leaving little or none for our benefit.
We need 10 minutes a day (fair-skinned) to 20 minutes a day (tanned) with the sun high in the sky, no clouds, and no glass. This can give us all of the vitamin D we need, but for many, this is impossible.
For those living a long way from the equator, or out of the tropic areas in winter, those working shifts or indoors, those who cover their entire bodies for religious reasons, or slap on sunscreen, those who have very dark skin, those on statin medication, those on a poor diet, those confined to hospitals or nursing homes and others who mistakenly believe the sun is evil, will never get enough vitamin D.
Vitamin D is fat-soluble, meaning that if we get plenty one day and miss the sun for a few days, we will still be able to call on our vitamin D reserves stored in fat cells.
Of course, UV-B will still damage our skin if we stay out in the sun too long.
UV-C
UV-C rarely gets to Earth as it is almost completely absorbed in the atmosphere, so is of little concern unless you are an astronaut.
Why we NEED sunlight, more than just for Vitamin D3
The human body is designed to thrive in sunlight, and it is not only the Vitamin D3 benefit.
A 20-year study of over 29,000 people found that those avoiding sun exposure had double the death rate from all causes!
This study did not measure D3 levels, but results from other D3 studies show that the high death rate from insufficient sun exposure can not be accounted for only by low Vitamin D3.

We also get Cholesterol Sulfate from sunlight on the skin.
Cholesterol sulfate protects red blood cells from breaking up. Without enough cholesterol sulfate, we get a condition called hemolysis, where the red blood cells die prematurely, spilling their contents into the blood.
Without sulfur, and without the sun, we cannot make cholesterol sulfate, a molecule which is both fat-soluble and water soluble, which is essential for the body to distribute cholesterol and sulfur throughout the body.
Artery walls have an endothelial lining, and these endothelial cells cannot work correctly when depleted in sulfate. They cannot control what gets into and out of cells, which promotes cardiovascular plaque.
Cholesterol Sulfate, in conjunction with it’s nitric sister, eNOS, determines how thick or thin or blood becomes. Sulfate makes it thicker, nitric makes it thinner, and this automatic regulatory system works very well as long as we have supplies of both, for which we need sunlight.
Interestingly, one thing that messes up these molecules is glyphosate (“Roundup” and other weedkiller trade names) so this is a good reason to avoid all GM (Genetically Modified) foods, which are all heavily sprayed with glyphosate.
Sulfur is incredibly important for health. Cholesterol sulfate protects against bacterial and virus infections and strengthens the immune system.
Cholesterol sulfate is essential for babies. Women normally have about 1.5 units of cholesterol sulfate in the blood, but in pregnancy, levels rise in the villi of the placenta to around 24 units!
Foods high in sulfur include eggs, beef, garlic, onions, sprouts, asparagus, kale, coconut oil, olive oil, but only where they are grown or raised in sulfur-rich soil (think organic).

Vitamin D sulfate is also made from sunlight, and is both water and fat soluble, so it can go anywhere in the body, distinct from the regular fat-soluble Vitamin D3 I have been talking about. Same with cholesterol sulfate. Not only is it both water and fat soluble, it can travel through the body on it’s own, where many other substances need to be “carried” by cholesterol wherever they need to go.
If we want healthy blood, we MUST have sunlight!
Humans make several other important peptide and hormone “photoproducts” when skin is exposed to UVB sunlight:

    • β-Endorphins are natural opiates that induce relaxation and increase pain tolerance
    • Calcitonin Gene-Related Peptides are vasodilators (expand blood vessels) that protect us from hypertension (blood pressure), vascular inflammation, and oxidative stress
    • Substance P is a neuropeptide that increases blood flow and also regulates immune system response to acute stressors
    • Adrenocorticotropic Hormone is a polypeptide hormone, controlling cortisol (stress hormone) release by the adrenal glands, regulating immune system and inflammation
    • Melanocyte-Stimulating Hormone is a polypeptide hormone, reducing appetite, increasing libido, and increasing skin pigmentation

Sunlight contains a beneficial EMF (electromagnetic frequency) that is essential for health.
40% of sunlight is infrared, and the red and near-infrared frequencies interact with CCO (Cytochrome C Oxidase). CCO is a protein in the inner mitochondrial membrane, also part of the electron transport chain. CCO is a chromophore (a molecule that attracts and absorbs light), so sunlight improves ATP (the generation of energy). The optimal wavelengths for CCO are red at 630 nm to 660 nm (nanometers) and near-infrared at 810 nm to 850 nm.
LeanMachine gets sun exposure as often as possible. Others afraid of the sun may consider photobiomodulation therapy (use of near-infrared light treatment).
UVA exposure is generally considered harmful, as this is the most damaging kind of exposure for skin with no ability to generate Vitamin D, however there are benefits such as releasing nitric oxide, discussed above. An important cellular signaling molecule that dilates blood vessels and reduces blood pressure.
This is closely tied to another molecule, eNOS (endothelial nitric oxide synthase) which regulates the “thickness” of blood. When blood becomes too thick, eNOS makes more nitric oxide wich expands blood vessels and thins the blood. When blood is too thin, eNOS makes more sulfate. Sulfate is essential for the endothelial lining of all blood vessel walls. If we are low in sulfate, the wall can start breaking down and clots start to form to repair the damage. We can get more sulfur in the diet from onions, garlic, broccoli, egg yolks and other foods, or by supplements such as MSM (MethylSulfonoyl Methane) but we still need sunlight to make cholesterol sulfate which can be distributed through the body to keep us alive!

Apart from photoproducts, nitric oxide and cholesterol sulfate production, sunlight is essential for our circadian rhythm (body clock). Sunshine activates neurons in the suprachiasmatic nucleus of the hypothalamus, sending signals to the pineal gland which regulates production of the hormone melatonin. When the circadian rhythm is upset, melatonin and other hormone production is disrupted, leading to mood problems, poor cognition (thinking), metabolic syndrome (leads to diabetes) and increased risk of cancer.
Tanning Beds
Tanning beds are famous for increasing risk of melanomas, the most deadly form of skin cancer.
Tanning beds have been outlawed in all States of Australia, except in the Northern Territory, where they are still legal, but there are no commercial solariums there because the tropical climate makes sunlight tanning easy. However, this is seen by some as a knee-jerk reaction by politicians to win votes.
Most tanning beds produce UV-A and UV-B radiation, but some better units are available which produce only UV-B, which are much safer if used correctly.
Staying too long in even a quality tanning bed will cause skin damage, a precursor to many forms of skin cancer. Tanning beds that emit high levels of UV-A should be avoided completely.
D3 from food
We get some vitamin D from the diet. Eggs, fish, cod liver oil are all good sources, and also come naturally with vitamin A, but it is almost impossible to get enough D3 from the diet, so we must top up our D3 from sunlight or supplements or both. Milk contains some vitamin D, but calcium and vitamin D in milk are very poorly absorbed. People in Asian countries who do not normally drink milk generally have stronger bones than people who drink milk.
D3 from supplements
Most D3 sold in Australia from chemist shops or supermarkets contain 1000 IU which may be enough to prevent rickets in young people, but is nowhere near optimum for immunity and bone strength, especially in older people, and not enough for anyone except small children to have an optimal immune system.
LeanMachine recommends Vitamin D3 5000 IU daily for almost a year’s supply, and this is the cheapest health insurance anyone can buy!
Vitamin K2 MK7 is also recommended, as this combination helps put calcium where it belongs, in bones and teeth, and reduces calcium buildup in blood vessels (arterial plaque)
Vitamin A is also recommended for health benefits as well as to eliminate any chance of toxicity.
No Cholesterol means no Vitamin D3.
As explained above, cholesterol is the building-block for vitamin D3, also for every hormone in the body and many other functions.
About half the adult population over 60 in Australia and the USA is taking statin medication.
Sold under many names including Simvastatin, Lipitor, Advicor, Lovastatin, Mevacor, Vytorin, Zocor, Lipex, Simcor, Crestor, Pitavastatin, Pravastatin, Rosuvastatin, Fluvastatin, and Cerivastatin (withdrawn 2001).
The Lies about Cholesterol
Statins do lower cholesterol, but we NEED cholesterol, it is NOT the enemy it is made out to be.
Yes, cholesterol is found in a badly inflamed body, but this is because the liver makes more cholesterol to repair damage caused by the inflammation, which is the REAL cause of poor health.
Statins reduce cholesterol by preventing the liver from producing as much cholesterol, but the job of the liver is to make cholesterol as required.
If we eat cholesterol foods (such as meat or eggs) the liver makes less, if we eat no cholesterol (such as a vegan diet), the liver makes more, which is the way it should be.
When statins are used, they attempt to shut down this natural process, and in so doing, also shuts down co-enzyme Q10 which is vital for healthy muscles.
And the heart is the most important muscle in the body – why clobber it with statins?
Statins also stop production of 7-dehydrocholesterol, so then we get almost zero vitamin D3 from sunlight.
Statins have shown no benefit to women whatsoever in many studies.
For men who have had a heart attack, statins have shown a slight reduction in deaths from future heart attacks, but in all patients, statins cause an INCREASE in deaths from all other causes!
Because statins knock out our Co-enzyme Q10 (often called the spark-plug for the heart), the patient can suffer extensive muscle damage, causing pain, reduced mobility and even death.
Drug companies say they have no idea what causes this increase in death from statins, but the answer is obvious to me – low vitamin D3!
Studies show that treatment with one fish oil capsule daily prevented 9% of deaths in cardiac patients over 4 years, while those given the Crestor statin drug had an INCREASED death rate of 1% over the same period.
The Framingham study, the biggest and longest study ever, showed that those with the lowest cholesterol died first, and those with the highest cholesteol lived longest!
But the drug companies continue to perpetuate these cholesterol lies to maximise profits from their biggest-selling drug.

How much D3 do we need?
The older we get, the more vitamin Vitamin D3 we need.
The only way to know how much we have is by a blood test, because ethnic background, skin colour, amount of tan, food, medication, supplements, geographic location, sun exposure, clothing, sunscreen, exercise, BMI and many other factors determine how much Vitamin D3 we absorb and retain.
Vitamin D3 is a fat-soluble vitamin, so daily levels do not vary much, as every fat cell in the body can store D3.
Always ask the doctor for a printed copy of your results so you can compare with any previous test and also get a true reading.
Unfortunately, most Australian labs say we need 60 to 160 nmol/L of D3, which is inadequate. Better labs say 75 nmol/L is the minimum.
Values above 60 will prevent us from getting rickets, but will not give us good immunity.
For optimal immune system function, we should aim for the high end of the range of 125 to 175 nmol/L.
If we are battling cancer or some other serious disease, we should aim for 175 to 250 nmol/L but this requires careful monitoring and extra vitamins K2 and A to prevent toxicity.
Supplement values vary, and the RDA (recommended Daily Allowance) of 60 IU was alarmingly too low, and changed to 400 IU, originally determined as the minimum amount to prevent rickets.
Even the 400 IU allowance typically gives a blood test of 40 to 60 nmol/L which may barely stop rickets but will not provide a strong immune system.
Conservative studies determine that infants less than one year old need 400 IU daily, 1 year to adolescents need 400-600 IU daily, adults need 400-600 IU daily, and adults aged over 70 years need 400-800 IU daily.
More modern studies recommend babies take 400 IU, children 1000 IU, adults 4000 IU, and those over 70 may need 8000 IU daily.
Small doses are fine for strong bones, but for a strong immune system to ward off all disease, high doses are a must.
LeanMachine has taken 5000 IU daily for over 6 years, and has zero colds, flu or any other illness, not even a headache!

But don’t I get my Vitamin D3 from Milk?
Sorry, but you do not!
I was told to drink milk as a youngster, some 6 decades ago, and milk does indeed contain vitamin D and calcium, but these and other nutrients in milk are poorly absorbed in the gut.
Worse, pasteurised milk has most of the nutrients heated out of it, and homogenisation is very BAD for our health.
Homogenisation is a process making each fat globule 10 times smaller than normal, to save us the trouble of shaking the milk container to disperse the cream. The problem then is that these tiny fat globules then enter the bloodstream through imperfections in the gut lining, often referred to as “leaky gut syndrome”. When raw milk fat enters the blood directly like this, the immune system detects this as a foreign substance, and begins attacking these fat globules, and marks them as invaders. Now when we consume milk the regular way, and absorb it naturally through a healthy intestine, the immune system starts attacking this as well, as it has already been recognised as a foreign invader. The result: Allergies to Lactose, one of the main ingredients in milk, has reached epidemic proportions in the last few decades where homogenisation has become standard practice. Vitamin D3 can help stabilise an over-reactive immune system, but the only safe way to drink milk is to only use NON-HOMOGENISED milk. Most supermarkets have it, but you have to look past the big-name brands to find it.
In many countries it is against the law to buy non-pasteurised milk, but we can at least buy non-homogenised milk if we feel we must have milk (and we do not need milk).
Some Asian countries have diets where milk is non-existent, and their bones are stronger, and osteoporosis is very rare.
We get more useful Vitamin D3 from broccoli and other fresh vegetables than from milk!
Milk is also BAD for our bones, as it is acid-forming in the body, and all acids in the blood cause an immediate reaction in the body to neutralise the blood acid (otherwise we die!).
This reaction, controlled by the parathyroid glands, leaches potassium, calcium and magnesium from bones, teeth and organs, the fastest way the body can neutralise the acid.
If we must drink milk (and we do not have to for a healthy diet) then the ONLY milk to buy is FULL CREAM, UNHOMOGENISED milk, which you can find at good supermarkets if you look hard enough.
The only better product is the milk straight from the cow, or better still straight from mother’s breast (most mothers will not be impressed if you ask for milk this way!)
Getting enough of the right vitamin D3
Sunlight is still the best way to get enough Vitamin D3 and Cholesterol Sulfate, but for many, this can be difficult or impossible.
Supplements are the next best choice, but the supplements we buy at Chemist shops or supermarkets in Australia have only around 1000 IU of Vitamin D3.
They are also often combined with Calcium, which LeanMachine does NOT recommend, but that is another story.
While this is better than nothing, most people require 5 to 10 times this much to bring their levels to “optimum”.
For most health specialists, “optimum” means over 60 or 75 nmol/l (30 ng/ml), and if your results come in at over this threshold, the doctor will say you are fine.
However, true experts in this field say that truly optimum for a normal healthy person for immunity to disease, is between 125 and 175 nmol/L (50 – 70 ng/ml).
For those recovering from a serious disease, optimum should be 175 to 250 nmol/L (70 – 100 ng/ml).
Vitamin D3 can be toxic at high doses for extended periods, so continuous levels over 250 nmol/L (100 ng/ml) should be avoided.
Blood tests are advised for all very high-dosage patients.
People most at risk of deficiency are the elderly, those with with dark skin, those who cover their body with clothing or sun screen, or work night shifts or underground and never see the light of day, and those who live furthest from the equator or in cloudy climates.
Those at risk may need 10,000IU daily supplements, the rest of us can usually get plenty with 5000IU, and the very young who get plenty of sunlight on a regular basis may not require any.
Remember that we only get Vitamin D3 from sun in a blue sky when the sun is high, from the UVB (Ultra-Violet light in the “B” range”).
When the sun is low in the sky, or when there is cloud, or when the light comes through a glass window, UVB is blocked and we only receive UV-A which is the damaging, cancer-causing radiation with Zero Vitamin D3 benefits.
Other tests: Depending on the condition, the doctor may order other tests to check for liver and kidney disease as well as a full blood count.
A full blood test for Vitamin D3 is:
25-hydroxyvitamin-D (25-D or D2/D3) or 25(OH)D or simply 25-D
1,25-dihydroxyvitamin-D3, or 1,25(OH)2 D3, or 1,25 2(OH), or simply 1,25-D
Most doctors will only test for 25(OH)D which is the storage form, which is fine for most people.
For those suspected of having Sarcoidosis (a rare condition) then both must be tested, and vitamin D supplementation and sunlight should be avoided altogether unless the active form 1,25(OH)2 is tested low.
Vaccinations
There are many reports of children suffering from Autism and other serious conditions after vaccinations.
Vitamin D3 supplements should be taken for at least 1 week before any vaccination to reduce risk of unfortunate reactions.
Panadol, Panadeine, Paracetamol, Tylenol, Acetaminophen, Atasol, etc must NEVER be taken before or after any vaccination, even though doctors incorrectly recommend it to reduce pain and fever.
Autism rates in the USA are 1 in 45, while Autism rates in Cuba are 1 in 12,000.
A few decades ago, Austism rates were only around 1 in 200, before Panadol (Tylenol, Acetaminophen in the USA)
Cuba has a high vaccination rate of 97%, but the difference:
These over-the counter pain medications are prescription-only items in Cuba.
Of course, no drug company is interested in conducting a study where the result may be that their “safe and effective” product causes Autism, but as far as LeanMachine is concerned, Vitamin D3 reduces the risk of sickness from almost any disease.
Besides Autism, Panadol can destroy liver function (most patients on the liver transplant waiting list are there because of Panadol), and Panadol is also acted upon by enzymes which then destroy the body’s reserves of L-Glutathione, the natural “Master Antioxidant” in the body.
If you want your child vaccinated anyway, DO give them vitamin D3 and DO NOT give them any pain or fever medication.
A little fever is the body’s way to fight the toxins in the vaccination and the best way to deal with it is to let it run it’s course.
However, a very high fever can lead to convulsions, especially in small children. The best way to bring down a very high fever is to place the child in a cool to lukewarm bath and keep water over the skin using a sponge or cloth.
No drugs required, and much safer and more effective than any drug.
Better still, vaccinations can be avoided altogether for those with a strong immune system.
For more information on vaccinations, see this article: Vaccinations.
Autoimmune conditions
Allergies, hives, arthritis, lupus, psoriasis, rheumatoid arthritis, thyroid disease, multiple sclerosis, etc, are all autoimmune conditions.
Little help is available from medications which merely help to ease symptoms.
Vitamin D3 builds the immune system and protects us from colds, flu and other diseases, but Vitamin D3 is also an Immune Moderator, helping to dampen the efect of the immune system over-reacting, the cause of auto-immune disease.
Vitamin D3 can also help treat the cause of the symptoms, often Helicobacter pylori (H. pylori), found in over 70% of autoimmune patients.
H. pylori can invade the gut via contaminated water or food, or from contact with infected people or animals, causing gut inflammation, disrupting the immune system.
D3 effectively destroys H. pylori and restores the immune system, often reducing allergy symptoms by 30% in seven days, and another 40% in 12 weeks.
H. pylori infects around 30% of adults in the western world, more if we are over 60 with low D3 levels.
A blood test can give your D3 levels, but the lab will say 60 to 75 nmol/L is OK, but we need 125 nmol/L minimum to destroy H. pylori.
Mushrooms, eggs, wild-caught salmon, etc have natural vitamin D3 but the modern Western diet is lacking in these. Mushrooms grown in the dark will have no vitamin D3, but 30 minutes of exposure to direct sunlight can generate significant D3 levels.

Vitamin D3
The latest science Says: “It’s not just about bones, it’s about your total well-being!
Professor Michael Holick:
We now think that maintaining adequate vitamin D3 levels are important for decreasing the risk of prostate cancer, breast cancer and colon cancer.
There is some evidence that in young children if they are fortified with vitamin D3 from 12 months old it can reduce the risk of type 1 diabetes by 80%“.
Professor Philip Sambrook:
We have always thought it could not happen in Australia – it is too sunny a country. However, people do not get sunlight for various reasons and if you do not get some sunlight you do not make vitamin D3. We do not get it much in food any more so for that reason, deficiency is quite common. And the vitamin protects healthy cells while also killing cancer cells.”
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Note: This shop is now closed, but each product page contains a link to the best supplier of that product.

Disclaimer
LeanMachine is not a doctor, and everyone should consult with their own health professional before taking any product to ensure there is no conflict with existing prescription medication.
LeanMachine has been researching nutrition and health since 2010 and has completed many relevant studies including:
Open2Study, Australia – Food, Nutrition and Your Health
RMIT University, Australia – Foundations of Psychology
Swinburne University of Technology, Australia – Chemistry – Building Blocks of the World
University of Washington, USA – Energy, Diet and Weight
Johns Hopkins Bloomberg School of Public Health, USA – Health Issues for Aging Populations
Johns Hopkins Bloomberg School of Public Health, USA – International Nutrition
Johns Hopkins Bloomberg School of Public Health, USA – Methods in Biostatistics I
Johns Hopkins Bloomberg School of Public Health, USA – Methods in Biostatistics II
Johns Hopkins Bloomberg School of Public Health, USA – Principles of Human Nutrition
TUFTS University, USA – Nutrition and Medicine
TUFTS University, USA – Lipids/Cardiovascular Disease I and Lipids/Cardiovascular Disease II
Technical Learning College, USA – Western Herbology, Identification, Formulas
Bath University, England – Inside Cancer
WebMD Education – The Link Between Stroke and Atrial Fibrillation
WebMD Education – High Potassium: Causes and Reasons to Treat
Leiden University Medical Center, Netherlands – Anatomy of the Abdomen and Pelvis
MIT (Massachusetts Institute of Technology) – A Clinical Approach to the Human Brain
LeanMachine has now examined thousands of studies, journals and reports related to health and nutrition and this research is ongoing.

Updated 3rd November 2019, Copyright © 1999-2019 Brenton Wight and BJ & HJ Wight trading as Lean Machine abn 55293601285

Posted by: | Posted on: September 15, 2019

Black Seed May Treat Hypothyroidism (Hashimoto’s Disease), Clinical Trial Reveals

© 14th September 2019 GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here www.greenmedinfo.com/greenmed/newsletter
Original article:
https://www.greenmedinfo.com/blog/black-seed-may-treat-hypothyroidism-hashimotos-disease-clinical-trial-reveals
Posted on: Saturday, September 14th 2019 at 7:15 am

This article is copyrighted by GreenMedInfo LLC, 2019

Black Seed May Treat Hypothyroidism (Hashimoto's Disease), Clinical Trial Reveals

A groundbreaking clinical trial indicates that the most common cause of hypothyroidism (Hashimoto’s disease) may be improved with the addition of only two grams of powdered black seed daily

A randomized clinical trial reveals that the ancient healing food known as nigella sativa (aka “black seed”), once known as the “remedy for everything but death,” may provide an ideal treatment for the autoimmune thyroid condition known as Hashimoto’s disease, which is the most common cause of hypothyroidism.

The study published in the journal BMC Complementary and Alternative Medicine evaluated the effects of nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) – 1, Nesfatin -1 and anthropometric features in patients with Hashimoto’s thyroiditis.

The study took 40 patients with Hashimoto’s thyroiditis, aged between 22 and 50 years old, and randomized them into one group receiving two grams of powdered encapsulated Nigella sativa and the other 2 grams starch placebo daily for 8 weeks.. Changes in anthropometric variables, dietary intakes, thyroid status, serum VEGF and Nesfatin-1 concentrations were measured.

The positive results were reported as follows:

“Treatment with Nigella sativa significantly reduced body weight and body mass index (BMI). Serum concentrations of thyroid stimulating hormone (TSH) and anti-thyroid peroxidase (anti-TPO) antibodies decreased while serum T3 concentrations increased in Nigella sativa-treated group after 8 weeks. There was a significant reduction in serum VEGF concentrations in intervention group. None of these changes had been observed in placebo treated group. In stepwise multiple regression model, changes in waist to hip ratio (WHR) and thyroid hormones were significant predictors of changes in serum VEGF and Nesgfatin-1 values in Nigella sativa treated group (P < 0.05).”

The researchers concluded:

“Our data showed a potent beneficial effect of powdered Nigella sativa in improving thyroid status and anthropometric variables in patients with Hashimoto’s thyroiditis. Moreover, Nigella sativa significantly reduced serum VEGF concentrations in these patients. Considering observed health- promoting effect of this medicinal plant in ameliorating the disease severity, it can be regarded as a useful therapeutic approach in management of Hashimoto’s thyroiditis.”

What is Hashimoto’s Disease and Why Does Synthetic T4 Fail To Improve Well-Being

Hashimoto’s disease can be a devastating condition, especially when treated with a conventional medical approach. Also known as chronic lymphocytic thyroiditis, it is a progressive autoimmune disease where, in the many cases, the thyroid gland is eventually destroyed. It is considered the most common cause of hypothyroidism in North America. Some additional salient facts are:

  1. About 5% of the U.S. population will be affected by Hashimoto’s thyroiditis at some point in their life.

  2. Hashimoto’s occurs up to 15 times  more often in women than in men. The highest density of Hashimoto’s cases are between 30 and 60 years of age.

  3. Postpartum thyroiditis occurs in about 10% of patients.

  4. Hashimoto’s related hypothyroid is often under-diagnosed because the reference ranges were drawn from an unscreened population likely inclusive of those already suffering from suboptimal thyroid function or outright dysfunction.

The standard of care is to ‘manage,’ or artificially suppress, modulate, and/or replace hormone levels. Hypothyroidism caused by Hashimoto’s thyroiditis is most commonly treated with synthetic T4 in an attempt to reduce TSH levels under 5.0 U/ml. This often results in the appearance of TSH normalization, with downstream adverse effects, and without concomitant improvements in well-being. Dr. Kelly Brogan, MD, further elaborates:

“For those who do receive the label of hypothyroid, they remain obliquely objectified by their lab work as their doctors use synthetic T4 – Synthroid – to attempt to move their TSH within range, more often leaving them symptomatic but “treated” because of poor conversion to active thyroid hormone (T3) and suppression of natural T3 production because of their now lower TSH.”

It should be noted that while synthetic T4 is described by its manufacturer to be “identical to that produced in the human thyroid gland,” it is in actuality quite different. This has to do primarily with the fact that while the primary structure of amino acids in synthetic thyroxine produced from genetically modified yeast is virtually identical to that produced by the human thyroid gland, the secondary, tertiary and quaternary folding patterns of that protein may differ in significant ways. Known as the protein’s conformational state, a slight change in folding structure can alter function profoundly. This could account for widespread reports of dissatisfaction among those treated with synthetic thyroid versus natural forms extracted from the glands of pigs.

Even if the T4 produced synthetically were identical in structure and function to natural T4, the reality is that virtually all T4 found naturally in the human body is not found in its free state.

Moreover, T4 is found inextricably bound together with T3, T2, T1, and calcitron, in the extraordinarily complex Thyroxine Binding Globulin (TBG) protein. Clearly, therefore, pharmaceutical preparations of isolated T4 can not be considered identical to whole-food complexed thyroid hormones derived from natural extracts.

In a post titled, “Natural Desiccated Thyroid and Synthetic are NOT the Same,” from thyroid-s.com, this point is driven home powerfully:

“To graphically illustrate the huge differences between Natural Desiccated Thyroid as compared to T4 Only Synthetics, please consider this graphic. It attempts to show the tiny T4, T3, T2, T1 and Calcitonin hormones tightly bound to the very large thyroglobulin molecules as found in Natural Desiccated Thyroid. Remember that the Thyroglobulin molecule is approximately 1,000 TIMES BIGGER than the T4 molecule. Then it also shows the tiny T4 molecules as found in synthetic T4 only products. The pharmaceutical companies would have us believe these are bio-identical. We will let you decide.”

Moreover, research published in 2010 in the Archives of Pharmaceutical Research shows that levothyroxine preparations are widely contaminated with a “mirror image” stereoismer called dextro-thyroxine at a level as high as 1-6% by dry weight. D-thyroxine violates the left-handed ‘chirality’ of natural thyroxine and is a powerful, cardiotoxic endocrine disruptor.

The process by which levothyroxine sodium is produced today is highly synthetic and involves the use of a wide range of chemicals. One patent describes the dizzyingly complex process as follows:

“The process for preparation of Levothyroxine sodium comprises the steps, wherein compound obtained from steps a-g is prepared by conventional methods, a. nitrating L-tyrosine to give 3,5- dinitro-L-tyrosine, b. acetylating 3,5- dinitro-L-tyrosine to give 3,5- dinitro-N-acetyl L-tyrosine, c. esterifying the compound obtained from step (b) to give 3,5- diπitro-N-acetyl L-tyrosine ethyl ester, d. reacting the compound obtained from step (c) with p-TsCI in presence of pyridine to give corresponding tosylate salt, which is further reacting with 4-methoxy phenol to give 3,5- DinKro-4-p-methoxy phenoxy-N-acetyl-L-phenyl alanine ethyl ester, e. the compound obtained from step (d) is hydrogenated to give 3,5-diamino-4-p-methoxy phenoxy-N-acetyl-L-phenyl alanine ethyl ester, f. the compound obtained from step (e) is tetrazotized and iodized to give 3,5-Diiodo-4-p- methoxy phenoxy-N-acetyl-L-phenyl alanine ethyl ester, g. the compound obtained from step (f) is O-demethylated, N-deacetylated, and deesterified using aqueous HI in acetic acid to give 3,5-Diiodo-4-p-hydroxy phenoxy-L-pheπyl alanine followed by preparing hydrochloride salt of same and isolating, drying it h. lodinating 3,5-Diiodo-4-p-hydroxy pheπoxy-L-phenyl alanine HCI salt using methyl amine,”

Clearly, synthetic T4 treatments, even if effective at suppressing TSH, may not produce clinical outcomes that translate into improvement in well-being. Nor do they address or resolve the root causes of Hashimoto’s, which include selenium deficiency, wheat intolerance, and vitamin D/sunlight deficiency [view studies on these links on our Hashimoto’s research dashboard], along with a wide range of still yet unknown environmental, dietary, lifestyle, and mind-body factors.  Perhaps this latest study on black seed provides a new avenue for mitigating and correcting the metabolic and endocrine factors that are disturbed in Hashimoto’s disease, or at least complementing conventional treatment with a food-based approach that can improve both the subjective and objective aspects of the disease.

For more information on natural and integrative approaches to thyroid disease visit the following resource pageson GreenMedInfo.com:

To learn more about the powerful health benefits of black seed visit our research dashboard on the subject: Nigella Sativa (aka Black Seed)

 

Originally published: 2017-03-12

Article updated: 2019-09-08

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.