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Reproduced from original article:
- Troponin is a protein responsible for helping to regulate contractions in skeletal and heart muscle. After comparing blood levels and age, data revealed a slight raise in all age groups increased the risk of early death, and those who were 18 to 29 years old had a tenfold higher potential risk
- High levels in people without a diagnosis of heart attack also had a higher risk of early death; high levels of troponin may be found after sepsis, stroke, pulmonary disease, chronic kidney disease and chemotherapy
- Symptoms of a heart attack are not always obvious, but immediate treatment improves the rate of survival and reduces the risk of heart muscle damage from lack of oxygen; women may experience different symptoms including anxiety, back pain, heartburn or extreme fatigue
- One study showed 70% of heart attacks could be prevented by eating a healthy diet, getting exercise, maintaining a normal BMI, not smoking and other health lifestyle choices. It is important to know your risk factors and take quick action even if you only feel like you might be having a heart attack
Statistics from the American Heart Disease 2019 update shows cardiovascular disease (CVD) is still the leading cause of death, although the rate decreased by 18.6% from 2006 to 2016.1 Despite this reduction, 1.05 million people were expected to have a coronary event in 2019, including 720,000 first time and 335,000 recurrent events.
Nearly every 40 seconds someone has a heart attack or a stroke. In 2014-2015 the annual financial burden for CVD was estimated at $351.2 billion. In the survey, the data showed awareness of the symptoms of a heart attack was low.2
This has a negative impact on early diagnosis and treatment of a heart attack, which is linked to a higher potential for survival and return to normal activities when more of the heart muscle can be saved.
According to the Centers for Disease Control and Prevention,3 nearly 47% of sudden cardiac death happens outside of a hospital, which suggests people may be unaware they have heart disease, or they don’t act on early warning signs of a heart attack.
Those at greater risk of a cardiac event include people who have other medical conditions such as diabetes or practice specific lifestyle choices, such as eating a poor diet, excessive alcohol use, smoking or lack of physical activity.
Protein Linked to Muscle Damage Raises Risk of Death
Once your heart has begun to be damaged by a heart attack, the heart muscle releases a protein, troponin, which is responsible for helping to regulate contractions in skeletal and heart muscle.4 Emergency room physicians test for blood levels of this protein, along with other clinical tests, to evaluate the likelihood a patient is having a heart attack.
The level of the protein and other test results help clinicians make choices about immediate treatment. A new analysis from the National Institute for Health Research Health Informatics Collaborative led by researchers from London looked at data from 250,000 patients who had troponin tests completed.
The information was grouped by age and then compared against the test results and the patient’s health outcomes in the following three years. The researchers were interested in comparing the differences in troponin levels across age ranges, specifically in the senior population, as well as investigating the significance of the different levels of the protein.
The new data showed even a slight raise in the level of protein was associated with an increased risk of early death in all age groups. They also found the higher the level, the higher the risk of death in those who had suffered a heart attack.
However, patients who had the highest levels had a lower risk of dying, which the researchers theorized was due to the likelihood the patient had an event requiring surgery that may have reduced the risk of death. The data also showed patients from 18 to 29 years with raised levels had a tenfold higher potential risk of dying than those in the same age range without raised levels of troponin.
When the patients were over 80 years with raised levels, 46% died within three years.5 The lead scientist of the study commented in a press release:6
“There have been many advances in treating heart disease yet it remains the leading cause of death in the UK and around the world. This is the first study to address the implications of raised troponin in a real world large sample of patients across a wide range of ages.
Doctors will be able to use this information to help identify the risk of early death in patients who have a troponin level measured; this could lead to interventions at a much earlier stage in a wider group of patients than are currently treated.”
Other Things Can Also Raise Troponin Levels
The results also revealed, even if the patient had not been diagnosed with a heart attack, those who had higher levels of troponin had an increased risk of death.7 When you are healthy, levels of troponin are low enough they are usually undetectable. The levels begin rising three to four hours after heart damage and may stay elevated for 14 days.
However, troponin protein may be released into your bloodstream following more than a heart attack.8 Physicians from the Cleveland Clinic discuss several other health conditions during which your body releases troponin, which may signal an increased risk of death without early treatment.
•Sepsis — This is a life-threatening condition triggered by a systemic infection that ultimately affects the function of your vital organs. Sepsis is sometimes referred to as blood poisoning and it is conservatively estimated to be responsible for 270,000 deaths each year.
Troponin elevations may be the result of a combination of renal dysfunction, massive inflammatory response and increasing levels of catecholamine damage to the heart.
•Stroke — An acute ischemic stroke may raise troponin levels by triggering a variety of cardiovascular responses increasing stress on the heart. Troponin levels may also rise through neurogenic heart damage and alterations to the autonomic nervous system control.
This results in a catecholamine surge and damage to the myocardium. Scientists theorize this may explain the presence of rising levels in an ischemic stroke in the absence of coronary artery disease.
•Pulmonary disease — A strain on the right side of the heart from pulmonary disease may mark right ventricular dysfunction or indicate severe disease and poor outcomes in those who have high pulmonary arterial pressure.
An acute exacerbation of chronic obstructive pulmonary disease has been linked to an increase in all-cause mortality with elevations of serum troponin.
•Chronic kidney disease — Troponin is cleared by the kidney, which may be one explanation for elevated levels in those with chronic kidney disease. Elevations may also be the result of elevation in proinflammatory cytokines and associated high blood pressure.
•Chemotherapy — Chemotherapy can induce cardiac toxicity through the production of oxygen free radicals and by disturbing mitochondrial metabolism. When left ventricular deterioration is associated with chemotherapy it is often irreversible. By monitoring troponin levels problems may be identified before cardiac symptoms are clinically evident.
Can You Have a Heart Attack and Not Know It?
Although the terms are used interchangeably, a heart attack and cardiac arrest are not the same thing. A heart attack affects the oxygen supply to your heart while a cardiac arrest affects the electrical impulse. During a heart attack, restriction of oxygen occurs with a blockage to the blood supply, but the remainder of the muscle continues to beat.
During a cardiac arrest, the electrical system is affected by conditions such as heart failure, arrhythmias or ventricular fibrillation, usually resulting in a loss of consciousness and heartbeat. In some instances, just before cardiac arrest, you may notice abnormal gasping or there may be seizure activity at the beginning of the event.
Symptoms of a heart attack are not always obvious. However, immediate treatment often results in higher survival rates and loss of less heart muscle from lack of oxygen. Common symptoms of a heart attack include:
|Chest pain or discomfort||Upper body discomfort||Shortness of breath|
|Breaking out in a cold sweat||Nausea||Sudden dizziness|
|Feeling unusually tired||Lightheadedness|
Not all heart attacks begin with crushing chest pain as is depicted on television or in the movies. Women are less likely to report chest pain during a heart attack and more likely to perceive the symptoms as stress or anxiety. Women use terms such as “pressure,” “tightness” or “discomfort” rather than chest pain.
While 30% of women will seek medical care compared to 22% of men, physicians tend to misdiagnose or dismiss the symptoms of a heart attack in women rather than men. Other symptoms that may indicate a heart attack is in progress include:
|Anxiety attack||Back pain|
|Extreme fatigue||Feeling electric shocks down on the left side|
|Numbness and stiffness in the left arm and neck||Feeling like there is a large pill stuck in your throat|
Know Your Risk Factors and Take Action
Research published in the American Journal of Cardiology found women who addressed six lifestyle factors had the greatest impact on their heart health. In the study, nurses were followed for 20 years, starting around age 37.
Those who adhered to all six guidelines lowered their risk of heart disease by 92%. Researchers on the team estimated more than 70% of heart attacks could be prevented by implementing:
|Healthy diet||Achieving a normal BMI (body fat percentage is more accurate)|
|Getting at least 2.5 hours of exercise each week||Watching television seven or fewer hours per week|
|Not smoking||Limiting alcohol intake to one drink or less per day|
While none of these factors should come as a surprise, they collectively have an impressive impact on your cardiac risk. With respect to BMI, note that your waist-to-hip ratio is a more reliable predictor of risk than BMI, as it reflects the amount of visceral fat you carry. Another factor that can increase inflammation, activate your sympathetic nervous system and trigger a heart attack is stress.
Additionally, sitting for long periods of time raises your risk of a heart attack. This means intermittent movement and spending time at the gym or exercising at home are important factors to lowering your risk of CVD.
Some of the uncommon symptoms may lead you to believe you are not having a heart attack. Even if you’re not sure, it is vital that you call for immediate emergency assistance as time is a significant factor in improving your potential for survival.
An ambulance is the best and safest way to reach the hospital because emergency personnel can use treatments enroute before reaching the emergency room. Emergency medical personnel would rather treat you for a non-life-threatening condition then have you die because you are unwilling to go for treatment.
Talk with your health care provider about your risks and keep important information with you in case of an emergency. For instance, write down all your medications and supplements you’re taking and have the card laminated, keeping it in your wallet or purse.
- 1 American College of Cardiology, February 19, 2019
- 2 Circulation, 2019;139(10) Awareness of Warning Signs and Risk Factors for CVD
- 3 Centers for Disease Control and Prevention, Heart Disease Facts, Early Action is Important for Heart Attack and Americans at Risk for Heart Disease
- 4 EurekAlert! November 20, 2019
- 5 Daily Mail, November 20, 2019, Para 4 after the FB share this and related articles banner
- 6 EurekAlert! November 20, 2019, Para 6
- 7 Daily Mail, November 20, 2019
- 8 Cleveland Clinic Journal of Medicine, 2018; 85(4):274
Reproduced from original article:
- The fact that the U.S. Centers for Disease Control and Prevention accepts millions of dollars from drug companies and vaccine makers may be at the heart of many harmful and nonsensical health recommendations
- The CDC has long fostered the perception of independence by stating it does not accept funding from special interests. In reality, it receives millions of dollars each year from commercial interests through its government-charted foundation, the CDC Foundation, which funnels those contributions to the CDC after deducting a fee
- Several watchdog groups — including the U.S. Right to Know (USRTK), Public Citizen, Knowledge Ecology International, Liberty Coalition and the Project on Government Oversight — are petitioning the CDC to cease making these false disclaimers and retroactively acknowledge conflicts of interest
- CDC accepted $79.6 million from drug companies and commercial manufacturers between 2014 and 2018 alone. Since its inception in 1995, the CDC Foundation has accepted $161 million from private corporations
- Government-chartered foundations allow corporations to fund and thereby control the work of agencies that are supposed to regulate them
The fact that the U.S. Centers for Disease Control and Prevention accepts millions of dollars in funding from drug companies and vaccine makers is no minor problem. It may in fact be at the very heart of why so many harmful and nonsensical health recommendations end up being pushed down our throats.
The CDC has long fostered the perception of independence by stating it does not accept funding from special interests. In disclaimers peppered throughout the CDC website1 and in its publications, it says the agency “does not accept commercial support” and has “no financial interests or other relationships with the manufacturers of commercial products.”
Several watchdog groups — including the U.S. Right to Know (USRTK), Public Citizen, Knowledge Ecology International, Liberty Coalition and the Project on Government Oversight — are now petitioning2 the CDC to cease making these false disclaimers.3
CDC Gets Millions From Corporate Interests
In reality, the CDC does in fact accept millions of dollars each year from commercial interests through its government-chartered foundation, the CDC Foundation, which funnels those contributions to the CDC after deducting a fee.4
On the CDC Foundation’s website, you’ll find a long list5 of “corporate partners” that have provided the CDC with funding over the years. The petition also points out that the CDC media office states the agency “has, can and does accept commercial support,” which is a clear contradiction to its printed disclaimers. Furthermore:
“CDC even accepts earmarked money via the CDC Foundation, allowing manufacturers to fund studies or programs whose results would either expand their profits or reduce their liability exposure,” the petition states.6
“For example, the BMJ reported that ‘in 2012, Genentech earmarked $600,000 in donations to the CDC Foundation for CDC’s efforts to promote expanded testing and treatment of viral hepatitis. Genentech and its parent company, Roche, manufacture test kits and treatments for hepatitis C’ …
The CDC Foundation also accepted $1.7 million from the Central American sugar industry for studies on chronic kidney disease which have been criticized for being biased towards the sugar industry, by not asking the best questions.”
CDC Petitioned to Quit Making False Claims
According to the petition,7 the CDC accepted $79.6 million from drug companies and commercial manufacturers between 2014 and 2018 alone. Since its inception in 1995, the CDC Foundation has accepted $161 million from private corporations.
As reported by the Lown Institute,8 which aims to advance “a just and caring system for health to replace the current, failing model rooted in profit-driven, low-value care”:9
“Many of these contributions could be seen as conflicts of interest — for example, a $193,000 donation from Roche, the maker of antiviral drug Tamiflu, to fund a CDC flu prevention campaign.
Despite the significant funding the CDC receives from industry via its foundation, few were aware of these conflicts until Jeanne Lenzer called attention to the foundation in The BMJ10 a few years ago.
Recently, the CDC accepted $3.4 million from Pfizer for the prevention of Cryptococcal disease, $1 million from Merck & Co. pharmaceutical company for a program on preventing maternal mortality, and $750,000 from Biogen for a program on screening newborns for spinal muscular atrophy …”
The petition asks the CDC to stop publishing the false and misleading disclaimers, remove all previously published disclaimers from the CDC website and its publications, and to issue corrections, retroactively disclosing the agency’s financial relationships with industry.
“By issuing these false disclaimers, CDC is misleading health professionals, consumers and others both in the United States and around the world,” the petition states.11
“This deception undermines CDC’s credibility and integrity. But the damage here is not merely to the CDC itself. CDC is a national and global leader on medical and public health matters. It is crucial for the CDC to lead by example on matters of ethics, and, at a minimum, to faithfully and truthfully disclose its conflicts of interest.”
Government-Chartered Foundations Gives Control to Industry
In a November 5, 2019, press release, Dr. Michael Carome, director of Public Citizen’s Health Research Group stated:12
“That the CDC accepts millions from corporations directly impacted by the agency’s public health programs is indefensible. So, the CDC instead has adopted the strategy of repeatedly denying that it accepts such payments.”
Gary Ruskin, co-director of USRTK added:13
“It’s time for the CDC to be truthful with health professionals and all Americans, and to stop denying that it takes corporate money. The CDC is violating the public trust by misleading us in this way.”
The CDC is supposed to be a public health watchdog. It has tremendous credibility within the medical community, and part of this credibility hinges on the idea that it’s free of industry bias and conflicts of interest.
By accepting money from drug companies and vaccine makers, one has to wonder whether that money might be having an impact on the agency’s health recommendations.
Again and again, investigations have shown that funding plays an enormous role in decision-making and in research outcomes. As noted by Shannon Brownlee, senior vice president for the Lown Institute, government-chartered foundations:14
“… exist at least in part because they allow industries to directly fund and thus control the work of agencies that are either supposed to regulate them, or conduct research that can help or hurt their business.”
Telltale Signs of Impropriety Abound
When you start to investigate, there’s no shortage of telltale signs suggesting the CDC isn’t nearly as independent as it claims to be. Some have already been noted in the CDC petition, but there are plenty of others as well.
For example, in 2016, Barbara Bowman, Ph.D., director of the CDC’s Division for Heart Disease and Stroke Prevention, quickly resigned after it was revealed she aided a Coca-Cola representative in efforts to get World Health Organization officials to relax WHO’s sugar limits.
I wrote about this in “CDC Executive Resigns After Being Caught Colluding with Coca-Cola to Salvage Soda Market.” Shortly thereafter, CDC director Dr. Brenda Fitzgerald was found to have received funding from Coca-Cola for her anti-obesity campaign, which had a near-exclusive focus on exercise, not the impact of soda and sugary junk food. This was reported in “Public Health Agency Sued for Coke Collusion.”
CDC Promotes Drug Industry Agenda
In a November 4, 2019, article15 in Eye on Annapolis, Josh Mazer discusses how the CDC is funding state health programs aimed at implementing mandatory HPV vaccinations:
“The Maryland Prevention and Health Promotion Agency (PHPA) has received millions … as part of an effort to require public schools to force children to get the human papilloma virus (HPV) vaccination.
Those funds came in the form of grants from the Centers for Disease Control and Prevention (CDC). The CDC maintains a nonprofit foundation that gets enormous amounts of money from Big Pharma — including Merck, the company that produces Gardasil, the HPV vaccine. At the very least, Maryland’s acceptance of those funds has the appearance of impropriety …
During a PHPA-hosted ‘HPV symposium’ attended by state pediatric practices and Maryland Department of Health staffers in March 2018 … the featured speaker — Dr. Alix Casler — encouraged attendees to offer free dinners, bottles of wine, and ‘Quality Doctor Incentives $’ sales bonuses to get Maryland physicians on board with the HPV vaccine-pushing program …
Casler offered a $5,000 cash payment to pediatric practices that achieve targeted HPV vaccine sales goals … Casler is a paid spokesperson for Merck …
In 2016, the Maryland Partnership for Prevention — which lists the Maryland Department of Health as its top member — accepted $70,000 from the Association of Immunization Managers (AIM).
AIM’s top ‘Corporate Alliance Members’ are Merck, Pfizer, Sanofi Pasteur and Seqirus. That same year, legislation was introduced in Maryland to mandate the shot … Despite the deaths and the ongoing health-safety questions related to the HPV vaccine, Maryland PHPA has continued using our schools to push Merck’s product.”
CDC Front Group Lobbies for Mandatory Vaccinations
Mazer’s observations are unlikely to be coincidental, as the CDC is a primary contributor to the National Association of County and City Health Officials (NACCHO), which lobbies for mandatory vaccinations and the elimination of personal belief exemptions to vaccination nationwide.16 As such, the CDC is actively using industry donations to promote a for-profit industry agenda.
It should be clear by now that the justifications given for why personal belief exemptions need to be abolished are nothing but a ploy to make money off mandatory vaccines.
In recent times, the measles-mumps-rubella (MMR) vaccine has been the target vaccine used to ban vaccine exemptions, under the pretense that measles is a lethal disease that needs to be eradicated. However, as predicted, it didn’t take long before other, completely unnecessary vaccines were tacked on to the mandated vaccines list.
As just one egregious example, a bill introduced in New York (S298/A2912) now seeks to require children to receive the HPV vaccine — one of the most dangerous and unnecessary vaccines ever made — in order to attend public school or day care.
There are hundreds of vaccines in the pipeline for children and adults, and once vaccine exemptions are eliminated in your state, you can expect many more to be mandated.
At that point, you’ll have no way of opting out of any of them. Measles was really just the Trojan Horse used to eliminate vaccine exemptions and strengthen mandatory vaccination laws. As noted by Children’s Health Defense in a June 6, 2019 article:17
“ACIP’s industry-beholden membership roster reads like a ‘who’s who’ of the individuals and organizations who spearhead the nation’s vaccine business … The agency’s involvement with vaccine manufacturers also extends to patents, licensing agreements and collaboration on projects to develop new vaccines.
In fact, the CDC and the National Institutes of Health (NIH) profit handsomely from their ownership or co-ownership with private sector partners of vaccine-related patents.
An early 2017 analysis of Google Patents results18 showed that the CDC held 56 patents pertaining to various aspects of vaccine development, manufacturing, delivery and adjuvants.
By May 2019, the search terms ‘Centers for Disease Control and Prevention vaccines’ retrieved 143 results in the Google Patents search engine,19 and a separate legal website displayed 10 screens worth of CDC patents,20 both vaccine- and non-vaccine-related.
The author of the 2017 analysis suggests that the large number of patents held by the CDC ‘deserves an in-depth review to determine exactly what current financial relationships with vaccine makers now exist and what…current impact those revenue streams are likely having on vaccine safety positions’ …
Some of the key technologies underlying the development of the HPV vaccines Gardasil and Cervarix emerged from research patented by the NIH’s National Cancer Institute (NCI), which then licensed the technology to Merck, MedImmune and GlaxoSmithKline. By 2009, HPV licensing had become NIH’s top generator of royalty revenues.”
Children’s Health Defense goes on to cite an in-depth investigation by Mark Blaxill, published in Age of Autism, in which he notes that:21
“Gardasil is perhaps the leading example of a new form of unconstrained government self-dealing, in arrangements whereby [HHS] can transfer technology to pharmaceutical partners, [and] simultaneously both approve and protect their partners’ technology licenses while also taking a cut of the profits.”
Your Help Is Needed!
To help push for greater transparency, please contact the U.S. Department of Health & Human Services today at firstname.lastname@example.org and let them know that you demand the CDC:
- Cease publication of disclaimers that CDC has “no financial interests or other relationships with the manufacturers of commercial products” and that it “does not accept commercial support.”
- Remove all such disclaimers from the CDC website, including the Morbidity and Mortality Weekly Report (MMWR).
- Add corrections to all MMWR articles bearing these disclaimers, explaining that the disclaimers were incorrect and have been removed.
- Retroactively disclose, in any MMWR article bearing the disclaimers, any corporate contributions to the CDC or CDC Foundation that are relevant to the MMWR article.
As noted by Lown Institute, disclosing existing conflicts of interests is an important first step in the creation of a “clearer separation between government agencies meant to serve the public interest and industry companies,” but it shouldn’t end there. We also need to abolish the loophole that allowed this hidden industry influence to take root in the first place — the government-chartered foundations.
“We need to question why these foundations exist and push for more public funding of these agencies, rather than force public health agencies to rely on industry funding for their programs and compromise their independence,” Lown Institute writes.22
- 1 CDC.gov MMWR Disclosure
- 2, 11 USRTK Petition to the CDC, November 5, 2019 (PDF)
- 3, 12, 13 USRTK November 5, 2019
- 4, 7 USRTK Petition to the CDC, November 5, 2019 (PDF), Page 3
- 5 CDC Foundation Our Partners: Corporations
- 6 USRTK Petition to the CDC, November 5, 2019 (PDF), Page 4
- 8 Lown Institute About Us
- 9 Lown Institute November 6, 2019
- 10 BMJ 2015;350:h2362
- 14, 22 Lown Institute October 25, 2018
- 15 Eye on Annapolis November 4, 2019
- 16 Sott.net March 6, 2016
- 17 Children’s Health Defense June 6, 2019
- 18 Google Vaccine Patent Search
- 19 Google Patent Search Engine Results
- 20 Justia Patents Assigned to CDC
- 21 Age of Autism, A License to Kill, Part 1
Reproduced from original article:
(NaturalHealth365) Ideally, the entire human body ought to work together, as a harmonious system, keeping us safe from harm and pain-free – all the days of our life. Naturally, if one part of the body doesn’t work well, it will affect other areas of the body. Having said that, oddly enough, most people have no idea how a simple vitamin D deficiency can be influenced by poor liver and kidney function.
Whether deriving vitamin D from food or the skin, both your liver and kidneys must be working correctly. In other words, poor kidney function, a fatty liver or other types of liver disease can result in a vitamin D deficiency, further affecting those organs and the rest of the body.
The link between poor kidney function and vitamin D deficiency
In addition, the kidneys are essential to helping the body produce vitamin D3 – which is the active form of this vitamin. They’re also critical for filtering and removing waste from your blood, maintaining proper pH, and regulating levels of chloride, sodium, bicarbonate, and potassium.
Studies have found that vitamin D levels have the potential to help predict the early signs of kidney disease. When the kidneys do not function correctly, they’re unable to provide the body with enough metabolic vitamin D, eventually resulting in additional symptoms related to a deficiency.
One study published in Ethnicity and Disease discovered that patients who have chronic kidney disease have an extremely high rate of severe vitamin D deficiency as well. Deficiency becomes a cycle because, with poor kidney function, deficiency becomes exacerbated because of the kidneys reduced ability to take vitamin D absorbed by the body and convert it into the active form the body can use.
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Anyone with low levels of vitamin D should also have their kidney function tested since the early stages of kidney disease often have few other symptoms.
Low vitamin D levels confirmed in people with fatty liver disease
Responsible for bile production, detoxification, synthesizing blood components, converting nutrients, and more, the liver is also an essential organ needed in the processing of vitamin D within the body. The liver produces the form of vitamin D known as calcidiol – which is the precursor to the active form of vitamin D.
Due to impaired synthesis, studies have found that low levels of vitamin D are quite common in individuals with liver failure.
Liver disease also can impair the absorption of the vitamin. Low levels of vitamin D, as well as bone disease, have been recognized for some time as complications of fatty liver disease.
However, studies have also confirmed low levels of vitamin D in individuals with noncholestatic (non-fatty) liver disease. In one study, more than 92% of patients with liver disease had some level of vitamin D deficiency, even in patients who were not currently in liver failure.
In many cases, fatty liver goes undiagnosed early on because it has few symptoms and may not show up in ultrasounds or liver function tests. Going forward, on a practical level, low levels of vitamin D could be a warning sign of a fatty liver and should be addressed, before it’s too late.
Editor’s note: Click here to access the Fatty Liver Docu-Class, hosted by your truly Jonathan Landsman. This event features 33 top experts on liver health and integrative healthcare. You’ll discover how to detoxify the body and avoid unwanted disease symptoms.
Sources for this article include:
What are Carnitines?
L-Carnitine is a food/supplement/amino acid, made in the body or ingested.
Best known for improving muscle growth, reducing excess body fat and repair of damage to the intestinal tract.
Carnitines aid fat loss by converting body fat into muscle or energy.
There are two main types of the five available, L-Carnitine and Acetyl L-Carnitine:
The Acetyl form of L-Carnitine is the biologically active version of the amino acid L-Carnitine, protecting all body cells from age-related degeneration.
The addition of the Acetyl group in the L-Carnitine molecule also allows it to pass through the blood-brain barrier where it can promote improved mental health and clarity.
Propionyl L-Carnitine is another version, less widely used.
GPLC (Glycine Propionyl-L-Carnitine) is another ester of carnitine used mainly as a sports supplement.
D-Carnitine supplements interfere with natural L-carnitine by preventing correct absorption of L-Carnitine and may also produce unwanted side-effects. This version should be avoided.
Sources of Carnitine
Carnitines come from the diet, or supplements, or the body can make them, although in smaller quantities.
The body can produce small amounts of L-Carnitine, if all precursors are present:
- Lysine – Amino acid
- Methionine – Essential Amino Acid
- Vitamin B3 (Niacin)
- Vitamin B6
- Ascorbic Acid
- Chelated Iron
If the body is deficient in any of the above, carnitine production is compromised.
The Carnitine Diet
Carnitines are found in animal products, particularly red meat, so vegans are usually carnitine-deficient.
Carnitines are made in the liver and kidneys, and stored in cells of the skeletal muscles, heart, brain, and sperm.
Carnitines are classified as “non-essential amino acids”, meaning the body can make them, as distinct from the “essential amino acids” which must come from the diet or supplements,
as they cannot be made by the body.
Carnitines carry fatty acids to the mitochondria (the energy-storage area in every cell in the body) where it is converted into ATP (Adenosine triphosphate, cellular fuel).
In the cells, carnitine is available to be burned as fuel, and also removes waste products from this process.
Kidneys remove carnitine if we have too much, and if we have too little, the kidneys hold on to any remaining.
Acetyl L-Carnitine can improve immune function and reduce lipofuscin, a cell-clogging pigment.
Acetyl L-Carnitine works with CoQ10 (Co-Enzyme Q10) and ALA (Alpha Lipoic Acid)
to further improve mitochondria function.
The Mitochondria is the “energy pump” within each of the 60 trillion cells in the human body. Without correct mitochondria function, poor health is the consequence.
Difference between Acetyl L-Carnitine and L-Carnitine
Acetyl L-Carnitine is not to be confused with regular L-Carnitine.
L-Carnitine is typically used for weight loss, athletes and body building, but without the brain benefits, as L-Carnitine cannot pass the blood-brain barrier.
Acetyl L-Carnitine is a highly bio-available form, able to cross the blood-brain barrier, helps to maintain normal neurotransmitter activity, commonly used for mental health, but also has muscle-building, fat-loss, immunity and general health properties.
Acetyl L-Carnitine Benefits
Carnitine can be used in conjunction with regular drugs for angina, and may improve exercise ability without chest pain.
Carnitine may help after a heart attack in conjunction with prescription medicines, although not all studies agree.
Carnitine may reduce chance of a second heart attack, death from heart disease, chest pain, abnormal heart rhythms, heart failure, heart muscle weakness.
Peripheral Vascular Disease
Atherosclerosis (hardening of the arteries, plaque build-up in the arteries) causes leg pain or cramps (intermittent claudication). Carnitine may allow more exercise before pain or cramps set in.
Diabetic neuropathy is a result of nerve damage from high blood glucose levels, causing pain and numbness, mainly in arms, legs, and feet. Acetyl-L-carnitine can reduce pain and increase feeling, and may even help regenerate nerves.
Carnitine is often used to increase performance, although evidence varies. Long-term results should improve as muscle replaces fat.
L-carnitine may help reduce fat, increase muscle, reduce fatigue, and improve the mental willingness to exercise.
Alzheimer’s Disease, Memory, Cognitive Ability
Acetyl L-carnitine may slow Alzheimer’s progression, senility, dementia, and improve nerve cell health, memory and cognitive ability.
Because of action on dopamine (chemical messenger between nerve cells) and dopamine receptors, Acetyl L-Carnitine may help minimise Parkinson’s symptoms, by enhancing dopamine release from dopaminergic neurons, and by improving binding of dopamine to dopamine receptors. Acetyl L-Carnitine also slows the decline in dopamine receptors as we age (which happens faster with Parkinson’s). Many researchers believe that Parkinson’s may be caused by a dopamine deficiency. Acetyl L-Carnitine may also help to inhibit tremors in Parkinsons patients.
Carnitine deficiency can lead to low sperm count and mobility. Supplemental Carnitine may help men struggling to conceive.
Propionyl L-carnitine and Acetyl L-Carnitine may improve ED (Erectile Dysfunction) and may improve Viagra effectiveness for male diabetics, vegans or those recovering from prostate surgery.
Peyronie’s disease is a penis curvature causing pain during erections. Acetyl L-Carnitine in studies worked better than prescription medication for reducing pain and assisted reducing penis curve, and without side-effects.
Carnitine can interact with some medications. Talk to your doctor if you are on any prescription medication.
Kidney disease can cause carnitine deficiency. Seek medical advice before using any supplements, especially those people on Dialysis.
L-carnitine may reduce symptoms of Hyperthyroidism (over-active thyroid), such as insomnia, nervousness, heart palpitations, high body temperature and tremors.
Carnitine may reduce passage of thyroid hormone into cells, so in theory, thyroid hormone replacement may become less effective.
This could be a problem for those with Hypothyroidism (low thyroid function).
If you take thyroid replacement hormone or have any thyroid issues, talk to your health care provider before taking any form of carnitine.
HIV – AIDS
AZT is medication for HIV and AIDS. L-carnitine supplements appear to protect muscle tissue from damage, a toxic side effect from AZT.
Doxorubicin is a chemotherapy medication for cancer. L-carnitine may protect heart cells from Doxorubicin’s toxic side effects (without reducing the chemotherapy effectivness).
Always talk to your oncologist for advice with chemotherapy. If your oncologist does not know, fine one who does know.
Accutane (Isotretinoin) a strong medication used for severe acne which can cause liver problems, as measured by a blood test, as well as high cholesterol and muscle pain and weakness.
These symptoms are like those seen with carnitine deficiency. Researchers in Greece showed that a large group of people who had side effects from Accutane got better when taking L-carnitine compared to those who took a placebo.
Depakote (Valproic acid) is an anti-seizure medication which can cause carnitine deficiency. L-carnitine supplements may reduce canitine deficiency and reduce side-effects of valproic acid. L-Carnitine is used medically where a patient has overdosed on Valproic Acid. However, Carnitine may increase seizure risk in those with a history or high risk of seizures, so talk to your doctor or neurologist.
Suggested Adult Use and Dosage
As a dietary supplement, take 500mg 1 to 3 times per day. Do not exceed 1500mg per day.
LeanMachine suggests 500mg daily as a maintenance dose, and up to 1500mg spread across the day for specific conditions.
Overdosing (5000 grams per day) may cause diarrhoea.
One 250mg capsule, taken 1 to 4 times daily. Always consult a qualified medical specialist if taking prescription medication or for any serious illness.
Updated 22nd September 2019, Copyright © 1999 – BJ & HJ Wight trading as Lean Machine abn 55293601285
Reproduced from original article:
by: September 2, 2019
(NaturalHealth365) Vitamin C, also known as ascorbic acid, is one of the most talked about (and studied) vitamins on the planet. Yet, despite all the scientific evidence, we still have too many people confused about its benefits – thanks to many misleading “nutritional” articles.
But, to be perfectly clear, vitamin C is absolutely essential for cardiovascular and immune system health.
In the 1980s, Nobel Prize-winning researcher Linus Pauling definitively linked vitamin C with heart health – and stressed the importance of sufficient supplementation. Now, integrative cardiologists – including Mathias Rath, M.D., and Thomas E. Levy, MD, JD – are continuing Pauling’s lifesaving work.
Unfortunately, too many conventionally-trained physicians view high-dosage vitamin C therapy with skepticism – no matter how impressive the results. Having said that, today we’ll focus on 6 of the greatest myths surrounding vitamin C.
Important point: Vitamin C deficiency is associated with heart disease
In Linus Pauling’s theory, heart disease is actually a manifestation of vitamin C deficiency. And atherosclerosis – with its attendant plaque deposits – is the body’s attempt to heal the cracks in arteries caused by the vitamin C shortfall.
Supplementation with high-dose vitamin C restores heart health in two ways.
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Vitamin C scavenges harmful free radicals that cause oxidative stress, while functioning as an important building block for collagen – a protein needed to promote healing, structure and stability in arteries.
Since the 1980s, a host of studies have helped to confirm Pauling’s theory.
In a paper published in Journal of Cardiology and Current Research, researchers reported that high-dose vitamin C reduces heart attack and stroke by up to 98 percent.
Now, let’s talk about those 6 vitamin C myths.
Myth #1: There are no studies on vitamin C
In his book Primal Panacea, high-dosage vitamin C pioneer Dr. Levy calls this statement “medical malpractice” and says it would be understandable if voiced by a mechanic or stonemason – but not by a physician.
Dr. Levy points out that a simple PubMed search yields over 60,000 studies on vitamin C – many of them showing positive effects on human health.
A board-certified cardiologist, Dr. Levy has written extensively on vitamin C, including a landmark review of 650 peer-reviewed studies on the effect of oxidative stress on vitamin C levels – as well as on the ability of vitamin C to reverse atherosclerosis.
Myth #2: There is no evidence that vitamin C works
Again, this is absurd.
Dr. Levy references over 1,200 studies showing beneficial effects – and says this only “scratches the surface” of what is known about vitamin C’s therapeutic abilities.
And, there is a problem with what constitutes a “study.”
In order to be acknowledged by the medical community, says Dr. Levy, a study must be large, randomized, placebo-controlled and double-blind.
At first glance, that sounds reasonable. But, are you ready for a shocker?
Dr. Levy maintains that most prescription drugs currently in use lack this type of rigorous study! (So why is vitamin C held to a stricter standard?)
Dr. Levy points out that a group of patients being given IV high-dosage vitamin C under closely monitored (hospital) conditions “does not count” as a study – even if all patients are cured!
To see evidence of vitamin C’s efficacy, one need look no further than the astounding success of Dr. Paul Marik at Sentara Norfolk Hospital.
Dr. Marik uses a mix of intravenous vitamin C, thiamine and corticosteroids to treat sepsis, a life-threatening systemic infection. To date, the groundbreaking therapy has saved 150 patients from almost certain death.
Myth #3: Vitamin C is unsafe
With a superlative safety profile (and no known lethal dose) vitamin C appears to be one of the safest substances on earth. In fact, natural health experts note that plain water is more toxic than vitamin C.
And, vitamin C seems to be free of dangerous side effects even at high doses.
The Rath Recommendations may call for over 10,000 mg of vitamin C a day – and some clinicians routinely use doses of 250,000 mg to 300,000 mg a day. This is an absolutely whopping amount that is over 3,000 times the RDA – yet no serious adverse effects have been reported.
Of course, check first with your integrative physician before beginning any supplementation routine.
It’s worth pointing out: pharmaceutical medications administered in hospitals kill thousands of patients a year. In fact, a recent Johns Hopkins study reports that 250,000 people die every year from medical errors – making it the third leading cause of death in the nation, right behind heart disease and cancer!
So, one has to wonder, why all the “controversy” surrounding a non-toxic substance like, vitamin C?
Myth #4: Vitamin C causes kidney stones
This myth is based on a medical fact, but is a myth nonetheless.
Experts say that vitamin C can – under certain conditions and in certain forms – contribute to oxalate production, which can in turn contribute to kidney stones.
But, Dr. Levy notes that the presence of high oxalate is not enough to create kidney stones.
For many, the matter was put to rest by a rigorous 14-year study of 85,557 women conducted by researchers at prestigious Harvard Medical School – in which the team found no link whatsoever between vitamin C intake and kidney stones.
Vitamin C has been further vindicated by additional studies, showing that the nutrient actually lowers the incidence of kidney stones.
Myth #5: You can get enough vitamin C through diet
The current RDA for nonsmoking adults is a paltry 60 mg of vitamin C a day – roughly the amount in one small orange. Although this is enough to prevent the serious medical condition known as scurvy, natural health experts decry it as ridiculously low.
Of course, more vitamin C is required to combat atherosclerosis and heart disease. In fact, one study showed that it takes 1,500 mg per day to prevent or reverse atherosclerosis in 60 percent or more of the population.
This would require consuming over a dozen red peppers and close to two dozen oranges – more than most people are willing to eat. And, when you consider that many people consume the Standard American Diet (SAD), notoriously low in fresh fruits and vegetables, the need for high-quality supplementation for most is clear.
Naturally, it doesn’t hurt to raise your dietary vitamin C intake as well – which you can do by eating organic citrus fruits, red peppers, strawberries, kiwi fruit and broccoli.
Remember: a wide range of factors – including infection, physical and emotional stress, dental toxicity issues, smoking, alcohol use, medications and environmental toxins – can drain the body stores of vitamin C.
Myth #6: Excess amounts of vitamin C are excreted through urine
Vitamin C proponents say that this is akin to saying that water is excreted in urine – which means that it is unneeded by the body – a clearly misguided belief.
The truth is, water performs many life-sustaining functions before being excreted – and the same is true of vitamin C. It is true that vitamin C is water-soluble – and, it is excreted through urine. But, not before it confers a host of cardiovascular benefits.
So, myths aside, we know that vitamin C is effective, non-toxic and safe. With heart disease claiming 640,000 lives a year, it seems unsafe not to use vitamin C to avoid unwanted health outcomes.
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