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The cancer fighting benefits of Coenzyme Q10

Reproduced from original article:
www.naturalhealth365.com/benefits-of-coq10-3221.html

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benefits-of-coq10

(NaturalHealth365) Coenzyme Q10, or CoQ10, is a substance found in every cell of our body. It is in a variety of foods, and healthy people are not likely to develop a deficiency of this nutrient. But, you might want to think about taking in some extra CoQ10 – especially if you’re taking a statin to lower your cholesterol levels.

CoQ10 has many potential health benefits, including possibly lowering the risk of certain cancers. Women, especially, should take note, since recent research points to links between breast cancer risk and lower levels of CoQ10 in the blood.

Clearing up the confusion about CoQ10

Coenzyme Q10 is technically not a vitamin because your body can synthesize it, so you do not need to get it from food. However, its structure is similar to that of vitamins. Also like vitamins, it acts as a coenzyme functions in your body’s metabolic reactions.

CoQ10 also has powerful antioxidant properties. For example, it helps prevent harmful oxidation of LDL cholesterol, and it supplements the work of vitamin E, or tocopherol. When your blood levels of CoQ10 are lower, your body needs more vitamin E from the diet to carry out heart-healthy antioxidant reactions.

What are the health benefits associated with CoQ10?

Can a Coenzyme Q10 deficiency increase the risk of cancer?

Since the 1960s, researchers have noted associations between lower blood levels of CoQ10 and cancer. People with lymphoma, myeloma, and lung, head, neck, and prostate cancers tend to have lower levels of CoQ10.

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A recent study looking into links between CoQ10 and breast cancer examined data from nearly 1,000 women aged 40 to 70 in the Shanghai Women’s Health Study. Those who had serum levels of CoQ10 in the bottom fifth of participants had a 90 percent greater chance of being diagnosed with breast cancer than those whose levels were in the middle fifth.

“The current Shanghai Women’s Health Study, with relatively larger sample size and longer follow-up time suggests an inverse association for plasma CoQ10 levels with breast cancer risk in Chinese women,” according to study authors Robert V. Cooney of the University of Hawaii and colleagues. Based on these results, future research should investigate potential effects of supplementation on the risk of breast cancer.

The study also confirmed the association between low CoQ10 and higher risk of cervical cancer, myeloma, and melanoma. This makes the results relevant to men as well as women. This study is far from definitive, but it seems likely that there is a link between healthy CoQ10 levels and reduction in cancer risk.

CoQ10 is in a variety of foods, including meat, fish, and eggs, and organ meats, such as heart, kidney, and liver, are especially rich sources. You can also find CoQ10 in plant-based foods, such as cauliflower, peanuts, soybean oil, and strawberries.

Obviously, you can obtain additional benefits, with ease, by supplementing your diet with a high quality CoQ10 supplement.

Sources for this article include:

Healthline.com
NaturalHealth365.com

8 Juicy Reasons to Eat More Strawberries

© 30th October 2019 GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here www.greenmedinfo.com/greenmed/newsletter
Reproduced from original article:
www.greenmedinfo.health/blog/8-juicy-reasons-eat-more-strawberries

Posted on: Wednesday, October 30th 2019 at 11:00 am

Who doesn’t love strawberries? And you don’t need any reason other than the pleasure of their sweetness to eat them every day. But according to researchers from Oklahoma State University, there’s lots more to strawberries than the flavor.[i]

Their study was published in the journal Critical Reviews in Food Science and Nutrition with funding from the NIH and the California Strawberry Commission. In it the researchers review over 130 studies attesting to the strawberry’s status as a “functional food.”

There is no regulated meaning for the term “functional food.” But it usually refers to a food that provides some benefit in addition to calories that may reduce disease risk or promote general health. That can be said of every fresh, organic whole food. But functional food is also a term that has become a marketing tool for food manufacturers who “enrich” their processed foods with vitamins, minerals, herbs and other supplements.

But strawberries don’t need any enriching. They consistently rank among the top fruits and vegetables for health benefits. They are full of powerful natural compounds that include:

  • Antioxidants – Strawberries were found to have higher oxygen radical absorbance capacity (ORAC) activity than black raspberries, blackberries or red raspberries.[ii] One study even found strawberries have the highest antioxidant capacity of ALL fruits and vegetables commonly available in the UK as measured by the trolox equivalent antioxidant capacity (TEAC) assay.[iii]
  • Polyphenols – Strawberries have been listed among the 100 richest sources of dietary polyphenols.[iv] They contain flavonoids like catechin, epicatechin, quercetinkaempferol, cyanidins, naringenin, hesperadin, pelargonidin, ellagic acid and ellagitannins. Flavonoids are free radical scavengers, and have anti-inflammatory effects. They also dilate blood vessels and slow tumor growth.
  • Vitamins and Minerals – Strawberries are high in vitamin C (ascorbic acid), B vitamins, vitamin E, folate, carotenoids and potassium.
  • Anthocyanins – These are water-soluble compounds responsible for the deep colors of berries and are among the principal bioactives in strawberries.
  • Phytosterols – These plant-derived sterols have structures and functions similar to cholesterol.

All of those natural components translate to a broad range of health benefits. Animal and cell culture studies show strawberries may be effective in reducing risk factors for cardiovascular disease including obesity, hyperglycemiahyperlipidemiahypertension, and oxidative stress.

Here are eight scientifically proven reasons to eat more strawberries:

1. Strawberries Lower Heart Attack Risk

In an analysis of data from over 93,000 subjects in the famous Nurses’ Health Study I and the Nurses’ Health Study II, researchers looked at the effects of eating strawberries and blueberries on cardiovascular health. They found that over a 14-year period, women eating just three servings weekly of blueberries or strawberries reduced their risk of heart attack by 33% compared to those eating berries once monthly or less.[v]

In addition, in an analysis of data from over 34,489 postmenopausal women in the Iowa Women’s Health Study, eating strawberries was associated with a significant reduction in deaths from cardiovascular disease over a 16-year follow-up period.[vi]

2. Strawberries Reduce Hypertension

Researchers again used the data from the two Nurses Studies as well as data from the Health Professionals Follow-Up Study to measure cardiovascular health benefits of strawberry and blueberry anthocyanins. They found that higher intakes of strawberry and blueberry anthocyanins (16-22 mg/day) were associated with a significant 8% reduction in the risk of hypertension. That was compared to those consuming only 5-7 mg/day of berry anthocyanins.[vii]

3. Strawberries Lower Inflammation and C-Reactive Protein (CRP)

In a study of 38,176 female US health professionals enrolled in the Women’s Health Study participants were asked whether they ate fresh, frozen, or canned strawberries “never,” or “less than one serving per month,” or up to “6+ servings per day.” Over an 11-year follow-up period, cardiovascular disease was lower among those consuming more strawberries.

CRP levels were significantly reduced among women consuming just two or more servings of strawberries per week.[viii]Elevated CRP is strongly associated with inflammation and is a high-risk factor for cardiovascular disease.

4. Strawberries Reduce Cancer Risk

In a prospective five-year cohort study in an elderly population, higher consumption of fresh strawberries and other fruits and vegetables was associated with significantly reduced cancer mortality. The authors attribute these observations to the carotenoid content of fruits and vegetables known to exert anti-carcinogenic effects.[ix]

In another larger five-year prospective cohort study, eating more foods from the Rosaceae botanical subgroup, including strawberries, was associated with a protective effect against esophageal squamous cell carcinoma compared to eating less of this fruit group.[x] The same cohort also reported reduced rates of head and neck cancer among those consuming more servings of the Rosaceae botanical subgroup including strawberries.[xi]

Other studies show that strawberries can even reverse early stage esophageal cancer.

5. Strawberries Reduce Oxidized Cholesterol

Studies show strawberries increase plasma antioxidant capacity helping to reduce oxidized LDL cholesterol. In human trials fresh, frozen, or freeze-dried strawberries were shown to reduce oxidative stress associated with metabolic syndrome or eating high-fat meals.[xii]

6. Strawberries Lower LDL Cholesterol and Raise HDL Cholesterol

The fiber, phytosterols, and polyphenols in strawberries have been shown to lower serum total and LDL cholesterol.[xiii] It’s also been shown to raise serum high-density lipoprotein (HDL)-cholesterol.[xiv]

7. Strawberries Help Control Blood Glucose Levels

Polypenols in a berry mixture that included strawberries produced a lower glucose response after eating a meal.[xv]

8. Strawberries May Help Reverse Age-Related Neurodegenerative Disorders

In an animal study researchers at the USDA Human Nutrition Research Center on Aging at Tufts found that strawberry extracts significantly reversed signs of age-related neuronal deficits.[xvi]

And animals eating a diet including 2% strawberries for two months showed significant protection from radiation damage to neurons.[xvii] Researchers suggest that strawberries and other berries may have a role in reversing Alzheimer’s disease or Parkinson’s disease.[xviii]

Are Fresh or Frozen Strawberries Better?

Studies show benefits to all forms of strawberries whether fresh, frozen, dried, pureed, or made into juices or jams. But the more they’re processed the more strawberries can lose some of their active compounds.

Frozen strawberries have significantly higher vitamin C (ascorbic acid) and polyphenols than freeze-dried or air-dried.[xix] Processing strawberries into juices and purees also results in a loss of ascorbic acid, polyphenols, and antioxidant capacity.[xx] And canning strawberries or making them into jams can significantly reduce the levels of anthocyanins and total phenolic compounds.[xxi]

Fresh or frozen are the best choices for health benefits when it comes to strawberries. But processed strawberry products still have some benefits and are a good choice when the real things aren’t in season.

Just remember to buy organic berries. Most conventionally grown strawberries are heavily sprayed with pesticides.

For more studies visit GreenMedInfo’s page on strawberries.

Originally published: 2014-10-07

Article updated: 2019-10-30


References

[i] Arpita Basu , Angel Nguyen , Nancy M. Betts & Timothy J. Lyons “Strawberry As a Functional Food: An Evidence-Based Review.” Critical Reviews in Food Science and Nutrition, (2014) 54:6, 790-806.

[ii] Wang, S. Y., and Lin, H. S. (2000). “Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage.” J. Agric. Food Chem. 48:140-146.

[iii] Proteggente, A. R., Pannala, A. S., Paganga, G., Van Buren, L., Wagner, E., Wiseman, S., Van De Put, F., Dacombe, C., and Rice-Evans, C. A. (2002). The antioxidant activity of regularly consumed fruit and vegetables reflects their phenolic and vitamin c compositionFree Radic. Res. 36:217-233.

[iv] P’erez-Jim’enez, J., Neveu, V., Vos, F., and Scalbert, A. (2010). “Identification of the 100 richest dietary sources of polyphenols: An application of the phenolexplorer database.” Eur. J. Clin. Nutr. 64:S112-S120.

[v] Aedín Cassidy, Kenneth J Mukamal, Lydia Liu, Mary Franz, A Heather Eliassen, Eric B Rimm. High anthocyanin intake is associated with a reduced risk of myocardial infarction in young and middle-aged women. Circulation. 2013 Jan 15 ;127(2):188-96.

[vi] Mink, P. J., Scrafford, C. G., Barraj, L. M.,Harnack, L., Hong, C. P.,Nettleton, J. A., and Jacobs, D. R., Jr. (2007). Flavonoid intake and cardiovascular disease mortality: A prospective study in postmenopausal womenAm. J. Clin. Nutr. 85:895-909.

[vii] Cassidy, A., O’Reilly, E. J., Kay, C., Sampson, L., Franz, M., Forman, J. P., Curhan, G., and Rimm, E. B. (2010). Habitual intake of flavonoid subclasses and incident hypertension in adults. Am. J. Clin. Nutr. 93:338-347.

[viii] Sesso, H. D., Gaziano, J. M., Jenkins, D. J., and Buring, J. E. (2007). Strawberry intake, lipids, c-reactive protein, and the risk of cardiovascular disease in womenJ. Am. Coll. Nutr. 26:303-310.

[ix] Colditz, G. A., Branch, L. G., Lipnick, R. J.,Willett,W. C., Rosner, B., Posner, B. M., and Hennekens, C. H. (1985). Increased green and yellow vegetable intake and lowered cancer deaths in an elderly populationAm. J. Clin. Nutr. 41:32-36.

[x] Freedman, N. D., Park, Y., Subar, A. F., Hollenbeck, A. R., Leitzmann, M. F., Schatzkin, A., and Abnet, C. C. (2007). Fruit and vegetable intake and esophageal cancer in a large prospective cohort studyInt. J. Cancer. 121:2753-2760.

[xi] Freedman, N. D., Park, Y., Subar, A. F., Hollenbeck, A. R., Leitzmann, M. F., Schatzkin, A., and Abnet, C. C. (2008). Fruit and vegetable intake and head and neck cancer risk in a large United States prospective cohort studyInt. J.Cancer. 122:2330-2336.

[xii] Paiva, S. A., Yeum, K. J., Cao, G., Prior, R. L., and Russell, R. M. (1998). Postprandial plasma carotenoid responses following consumption of strawberries, red wine, vitamin c or spinach by elderly womenJ. Nutr. 128:2391-2394.

[xiii] Basu, A., Fu, D. X., Wilkinson, M., Simmons, B., Wu, M., Betts, N. M., Du, M., and Lyons, T. J. (2010). Strawberries decrease atherosclerotic markers in subjects with metabolic syndromeNutr. Res. 30:462-469.

[xiv] Erlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P.,Mattila, P., and Jula, A. (2008). Favorable effects of berry consumption on platelet function, blood pressure, and hdl cholesterolAm. J. Clin. Nutr. 87:323-331.

[xv] T¨orr¨onen, R., Sarkkinen, E., Tapola, N., Hautaniemi, E.,Kilpi, K., andNiskanen, L. (2010). Berries modify the postprandial plasma glucose response to sucrose in healthy subjectsBr. J. Nutr. 103:1094-1097

[xvi] Joseph, J. A., Shukitt-Hale, B., Denisova, N. A., Prior, R. L., Cao, G., Martin, A., Taglialatela, G., and Bickford, P. C. (1998). Long-term dietary strawberry, spinach, or vitamin e supplementation retards the onset of age-related neuronal signal-transduction and cognitive behavioral deficitsJ. Neurosci. 18:8047-8055.

[xvii] Rabin, B. M., Joseph, J. A., and Shukitt-Hale, B. (2005). Effects of age and diet on the heavy particle-induced disruption of operant responding produced by a ground-based model for exposure to cosmic raysBrain Res. 1036:122-129.

[xviii] Joseph, J. A., Shukitt-Hale, B., and Willis, L. M. (2009). Grape juice, berries, and walnuts affect brain aging and behaviorJ. Nutr. 139:1813S-1817S.

[xix] Asami, D. K., Hong,Y. J.,Barrett, D. M., and Mitchell, A. E. (2003).Comparison of the total phenolic and ascorbic acid content of freeze-dried and air-dried marionberry, strawberry, and corn grown using conventional, organic, and sustainable agricultural practicesJ. Agric. Food Chem. 51:1237-1241.

[xx] Klopotek,Y., Otto, K., and B¨ohm,V. (2005). Processing strawberries to different products alters contents of vitamin c, total phenolics, total anthocyanins, and antioxidant capacityJ. Agric. Food Chem. 53:5640-5646.

[xxi] Ngo, T., Wrolstad, R. E., and Zhao, Y. (2007). Color quality of Oregon strawberries-impact of genotype, composition, and processingJ. Food Sci. 72:C025-C032.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.
LeanMachine Note: Strawberries may also be sprayed, so organic is best, and wash before eating.

Vitamin D3

Written by Brenton Wight – LeanMachine, Health Researcher.

Health Facts on Vitamin D3 – the Natural Cure for all disease!

Why we need Vitamin D3
First, to help absorb calcium and other minerals to build strong bones with the help of Vitamin K2 that keeps calcium in bones instead of in blood where calcium plaques form.
Second, to build the immune system, in conjunction with gut bacteria – the other half of the immune system story.
Depending on which study we believe, optimal vitamin D3 can prevent between 50% and 90% of all cancers, as well as Multiple Sclerosis, and reduce the intensity or even cure almost every other disease.
If a drug company developed something that would do this, it would make headlines around the world and win a Nobel prize, and many billions of dollars would be saved in the health care budgets of countries everywhere.
If the entire population had optimal Vitamin D3 combined with a healthy diet, countless lives would be saved from cancer, many illnesses would disappear, most artificial replacements of hips and knees would not be required, thousands of people clogging up the nursing homes in their wheelchairs would be out playing tennis and leading active, productive lives.
Have I convinced you yet that just a few dollars for a year’s supply of super-strength 5000 IU Vitamin D3 would be a good investment in your future?
If not, then perhaps you should go and reserve that spot in the nursing home, and pick out the burial plot while you’re at it!

Benefits of Vitamin D3

Studies show that Vitamin D3 has cancer inhibiting properties, especially breast, prostate, pancreas, colon, skin cancer and leukaemia.
While millions are spent trying to find a cure for cancer, Vitamin D3 could be used to prevent cancer in the first place, at a cost equivalent to a drop in the ocean.
Vitamin D3 deficiencies can cause the following:
Colds and flu:
Vitamin D3 helps prevent or reduce severity of colds, flu, and almost every other infection. LeanMachine is living proof. After 10 years of taking Vitamin D3, no colds, no flu, no infections of any kind, not even a headache!
When we look at studies funded by drug companies who manufacture vaccinations, which are always biased in favour of the flu shot, the NNT (Number Needed to Treat) for the flu vaccine is 40, meaning that to protect one person from getting the flu, 40 people must receive the vaccination. Compare this with Vitamin D3, where the NNT is 33 in the average population, and in those people with D3 deficiency, the NNT drops to 4. In other words, for the average person, D3 is significantly better than the flu shot, and for those with low Vitamin D3, D3 supplements work 10 time better than the flu shot!
Most infections are naturally destroyed by our own immune system, mainly the T-cells, but T-cells need Vitamin D3 to operate correctly.
Studies funded privately, without the influence of the drug companies, have foud the flu shot to be even less effective, with those over the age of 65, or under the age of 2, or those on statin medications, all receiving NO statistically discernible benefit from the flu shot, and everyone else receiving a very marginal benefit such as a reduction in duration of illness of about 1 day.
On the downside, those taking the flu shot every year received less benefit (less protection), and actually INCREASED risk of coming down with a different strain of the flu!
More on vaccinations under the heading below.
OA (Osteoarthritis)
Osteoarthritis (OA)is the most common disease in people over age 50, more common than the common cold, and especially in women.
OA is directly linked to Vitamin D3 deficiency, and higher Vitamin D3 levels lower the risk.
Studies show that hip fractures in high risk population groups can be reduced by up to 40% by supplementing with Vitamin D3.
Partly because bones are stronger, and partly because people with good Vitamin D3 levels have much better balance and stronger muscles, so don’t fall over as much.

RA (rheumatoid arthritis) and MS (Multiple Sclerosis) appear to have the same link.

Obesity
Most Australians (two thirds) and others in Western society are overweight or obese.
Two thirds of people in Western society are also deficient in Vitamin D3, and this is no coincidence. There is a direct link between Vitamin D3 deficiency and obesity.
On average, the more Vitamin D3 deficient a person is, the more obese they are.
Healthy levels of Vitamin D3 are seen mainly in lean, healthy people.

Chronic pain
Chronic pain from any source can be reduced with Vitamin D3, even a simple headache, migraine, back pain, fibromyalgia, etc.
Many people with osteoporosis have chronic pain, typically lower back pain, often a sign of D3 deficiency.
Those people usually exercise less because of the pain, and insufficient exercise causes depression, worsens their osteoporosis, increases obesity, and their condition only gets worse.

Before 2010, LeanMachine suffered from headaches back pain and other pain, but no more. If I hit my thumb with a hammer, of course it hurts, and if I strain my back or another muscle, I feel stiffness that goes away in a day or two. But no other pain, no painkillers required, and in fact no painkillers of any kind kept in the house.

Cancer
Cancer is a devastating condition, but high levels of Vitamin D3 offer up to 80% or more protection, especially childhood cancers, breast, prostate, pancreas, skin and colon cancer.
A recent study confirmed that women with high levels of Vitamin D3 had about 85% reduced risk of breast cancer compared to those with the lowest levels of Vitamin D3.
Vitamin D3 is critical to the body’s production of GcMAF, a cancer-fighting protein that inhibits cancer metastasis, and is capable of reversing the devastating effects of cancer on the body. Vitamin D3 supports GcMAF synthesis, helping to shut down pro-cancer receptors and enzymes that encourage metastasis.
DBP-maf(Vitamin D3 binding protein-macrophage activating factor) is another protein reducing cancerous activity, which directly stimulates the immune response by suppressing angiogenesis (blood vessel growth) required for cancer cell migration and tumor growth. DBP-maf requires Vitamin D3 for transport in the bloodstream.

Depression
There are links between low levels of Vitamin D3 and depression.
For depression sufferers, LeanMachine recommends extra Vitamin D3 from sunlight because getting outside in the sun always lifts our mood. If we cannot get out in the sun, supplementation is a must.

Hearing Loss
Vitamin D3 deficiency weakens our bones, but when the three tiny bones (hammer, anvil and stirrup) in the ear become weak and spongy, attenuation of sound transmission results in hearing loss.

Allergies
Recent studies show that children with allergies have a high chance of being deficient in Vitamin D3, and those with the worst allergies, are over 80% likely to be deficient in vitamin D3.

Heart disease
The number one killer of Western society people is still cardiac disease.
Vitamin D3 deficiencies bring on high blood pressure, stroke and heart attack.
Number two is cancer, so we can alleviate both killers easily by eating a healthy diet and getting enough Vitamin D3 from sunlight and/or supplements.

Type 1 diabetes

Pregnant women who are deficient in Vitamin D3 are far more likely to produce offspring with Type 1 diabetes.
Any child deprived of sunlight in the first few years of life also has a far higher risk of type 1 Diabetes.

How do we get Vitamin D3 ?

We get Vitamin D3 from the sun, but we need the basic building-blocks in the body first.
The normal process of Vitamin D3 metabolism can be stopped by the deficiency of one single nutrient, so a healthy, nutrient-rich diet is essential.
In particular, we need cholesterol, which has been demonised for decades. More on this later.

Vitamin K2 – No Bones without it

Some people say we need Calcium for strong bones, but we get plenty of calcium from the diet, and we can absorb calcium with no problems as long as we have enough Vitamin D3.
No vitamin D3 means no calcium absorption, so adding more calcium to the diet without vitamin D3 means potential for calcium to form as plaque in our arteries, kidneys or other places where it will only damage the body.
Vitamin K2, which comes from animal products such as chicken, cheese, butter, eggs, etc, can help build bones by directing calcium to bones and teeth where it belongs, and helps keep our arteries, kidneys and other organs free from calcium.
The only vegetable source of Vitamin K2 is Natto (fermented soy), which explains why Japanese post-menopausal women have much stronger bones than Western women, as Natto is part of the traditional Japanese diet.
Vitamin K2 is not to be confused with Vitamin K (or K1), which is required for effective blood clotting, but not as effective as Vitamin K2 for bones, but still desirable in the diet.
K1 comes from intestinal bacteria as well as from green leafy vegetables like kale, spring onions, brussels sprouts, cabbage, broccoli, basil, asparagus, also prunes.
For vegetarians or vegans, supplementation of Vitamin K2 is essential as well as D3 for healthy bones. Vitamin D3 metabolism is complex, where each essential and critical nutrient provides the path to the next step, and one missing link in the chain will stop the entire process.
So it is no surprise that a third of our population is deficient in Vitamin D3, and around 90% are less than optimal. Unfortunately, these are the people who are at the highest risk of cancer.

Importance of Diet

Vitamin D3 cannot form without basic nutrients for the multi-stage process and this explains why so many people are deficient.

D3 – A Vitamin or a Hormone?

The answer is both.
It is a hormone (a chemical messenger) because it controls cells, organs, muscle and bone in everyday function, and because the body can manufacture it with sunlight exposure on skin.
It is a vitamin because it binds calcium so we can absorb it, as we humans cannot digest calcium without Vitamin D3, which maintains calcium and phosphate concentrations in the blood, providing minerals for bones, nerves, muscles, immune function, and lowers inflammation.
Many cell functions are controlled in part by vitamin D3, aiding in weight loss, blood glucose regulation, metabolism, and essential fatty acids (Omega-3) processing.
There is no point taking calcium or omega-3 foods or supplements without a good supply of Vitamin D3.
Almost every cell in the body has Vitamin D3 receptors, so Vitamin D3 is a crucial nutrient.
Vitamin D, D2 or D3?
The terms Vitamin D and vitamin D3 are used interchangeably here. D3 is the correct and natural Vitamin D.
D3 exists in the body as the storage form 25(OH) and the active form 1,25 2(OH). Vitamin D2 (ergocalciferol) is an artificial version of Vitamin D3 (cholecalciferol), or vitamin D coming from some foods.
D2 has very low affinity for DBP (vitamin D binding protein) so it cannot be easily stored and should never be used.
Firstly, D2 has nowhere near the healthy properties of D3 (cholecalciferol), and secondly, D2 tends to block absorption of the real D3.
Many foods come “fortified with vitamin D” but this is invariably an artificial D2 with poor benefits.
Some early medical studies on vitamin D used inferior synthetic D2 which is toxic at much lower doses, and unfairly discredited the real D3 which was not even being used in the studies.

How is Vitamin D3 made?

We get vitamin D3 from sunlight, food or supplements.
D3 from sunlight
Most people know we get Vitamin D3 from sunlight, but there is a multi-stage process involved.
Production starts in the liver, which makes 7-dehydrocholesterol, which then migrates to the skin to be altered by UVB (ultra-violet light in the B range) to become pre-vitamin D3.
This is carried back to the liver to be mediated by an enzyme (25-hydroxylase) to become 25-hydroxyvitamin D, where a hydroxy (OH) molecule is added to build the storage form 25(OH).
This is then transported to the kidneys to be mediated by yet another enzyme (1-alpha-hydroxylase) to finally become calcitriol, where a second hydroxy (OH) is added. This is the active form of vitamin D3, also known as cholecalciferol or 1,25 dihydroxyvitaminD3 or the active form 1,25 2(OH). Dihydroxy means that the D3 molecule has two OH molecules added, one from the liver and a second from the kidneys.
Vitamin D3 is carried in the blood by DBP (vitamin D-binding protein).
This entire process takes around 15 days, so if we shower every day, we “wash off” most of the pre-vitamin D, so morning showers are best, allowing the pre-vitamin D to start the migration back to the liver before the next shower.
And a day at the beach won’t help our vitamin D3 if we go for a swim, and worse if we get sunburnt!

Statins rob our Vitamin D3

As we age, we lose the ability to synthesise vitamin D from sunlight, and those on statin medication (half the aged population) cannot make 7-dehydrocholesterol, co-enzyme Q10, Cholesterol Sulfate and other important requirements for the body, because when statins slow the liver production of cholesterol, all of the above are affected.
No one should ever take a statin drug (Lipitor, Crestor, Simvastatin and others) other than exceptional circumstances, as they generally do much more harm than good.
Independent studies show that while some deaths from heart disease are reduced, deaths from ALL OTHER CAUSES is INCREASED by statin medication! Taking statins, we will generally not live one day longer, and will have a poorer quality of life.
Also as we age, we generate less stomach acid, losing the ability to take in B12, Methyl Folate (never Folic Acid!), Vitamin K2 and other nutrients that vitamin D requires to do it’s job. If we get reflux or heartburn, doctors normally prescribe Nexium or antacids, which may relieve symptoms short-term, but only make the problem worse. The best way to cure heartburn is to eat less, and eat an alkaline-forming diet, but that is another story in my Alkaline Diet article.
Those who dress fully covered for cultural reasons or those with dark skin always need more vitamin D.
Annual blood tests for vitamin D3 are advisable if taken at very high doses as excess levels can become toxic.
For adults, toxic levels for vitamin D3 are generally not seen unless we take in some 40,000 IU daily for many weeks.
Vitamin A can also be toxic in high levels, but if A and D are taken together, the toxic levels are some 5 times higher for both A and D, giving a huge margin of safety, so old “toxic levels” should really be called “imbalance levels”.
Another factor is Vitamin K2, discussed later.

Other things that Steal our Vitamin D3

Being overweight – the more overweight we are, the less bioavailable Vitamin D3 becomes. But if we take Vitamin D3 supplements and/or get more sunshine, this will assist our weight-loss efforts!
Being old – as we age, our ability to absorb D3 from sunlight and from food reduces, so supplementation becomes more essential.
BPA (Bisphenol A) – BPA (Bisphenol-A) and other endocrine-disrupting chemicals reduce our Vitamin D3 levels. Avoid foods in plastic or cans and use glass containers.
Liver problems – a poor liver produces less bile, which reduces absorption of Vitamin D3. Look after the liver – avoid excess alcohol and eat a healthy diet of quality fats, few carbohydrates, and low to moderate protein.
Kidney problems – as kidney disease gets worse, so do Vitamin D3 levels. Look after kidneys by drinking plenty of clean water and eating a healthy diet
Gut bacteria – these 100 trillion organisms are a major component of our immune system, and also aid in absorption and processing of minerals and vitamins, including Vitamin D3. People with celiac disease, chronic pancreatitis, IBS (irritable bowel syndrome) or Crohn’s disease, or those taking antibiotics, will all have reduced D3, so essential supplements are Vitamin D3 and probiotics.
Slip, Slop, Slap in the face campaign – this disastrous campaign has been running for over 30 years in Australia, costing the taxpayer many millions of dollars, and has caused many more millions in extra health care, more disease, and many more lives lost.
True, reduced sunlight has reduced the number of mostly harmless skin cancers such as basal cell carcinoma and squamous cell carcinoma which are easily treated, and rarely turn into something more serious (less than 1% of cases).
But the number of MELANOMA cancers – the real, deadly kind, has DOUBLED, but this fact has been hidden by the Australian Cancer Council who are behind the Slip, Slop, Slap campaign! The primary reason, of course, is lack of Vitamin D3 due to reduced sunlight, reducing immunity.
Melanomas also appear on the soles of feet, in armpits and other places where sunlight is very limited, but so-called “specialists” still blame the sun!
The science cannot be denied. The closer one lives to the Equator, the less chance of any type of cancer, a proven fact.

Too much sunlight?

If we get D3 from sunlight, then surely if we spend all day in the sun, like construction workers and other outdoor activities, we should get plenty?
Wrong. After we spend around 10 to 20 minutes in the sun in the middle of the day (90 minutes for dark-skinned people), we reach a point where the body will no longer synthesise any more vitamin D3.
This is the way the body is designed to prevent toxic levels from building up, and also the reason why we get a tan – to prevent too much vitamin D3 from the sun.
If our skin starts to get the slightest shade of pink, it is time to cover up or seek some shade, as more sun will only then cause damage, with no extra vitamin D3 past that point.
And if we get a healthy dose of sunlight one day, we can happily work inside the next day, as it may take 2 days to build new skin resources for more absorption.

The Morning Myth

The cancer society and other “health” organisations all say the we should avoid the sun in the middle of the day, and only go out in the morning or the evening when the sun is low in the sky. Wrong again!
This is actually the complete reverse of the truth!
The sun produces ultra-violet rays in three bandwidths, named UV-A, UV-B and UV-C, each with different properties.
UV-A
We get UV-A from all sunlight, no matter what time of day, and it passes through cloud and glass, and this kind travels deeper into the skin, causes skin damage and ZERO vitamin D production.
We can sit by a window or in a car with windows up, on a hot sunny day and never get any vitamin D.
We can be outside all day when there is cloud cover, but we will never get any vitamin D.
All we get from UV-A is skin damage.
UV-B
We get UV-B ONLY from a clear blue sky, and ONLY when the sun is HIGH in the sky. This is the “good” sunlight, as this is the ONLY kind that gives us vitamin D.
When the sun is lower in the sky, most UV-B is absorbed in the atmosphere leaving little or none for our benefit.
We need 10 minutes a day (fair-skinned) to 20 minutes a day (tanned) with the sun high in the sky, no clouds, and no glass. This can give us all of the vitamin D we need, but for many, this is impossible.
For those living a long way from the equator, or out of the tropic areas in winter, those working shifts or indoors, those who cover their entire bodies for religious reasons, or slap on sunscreen, those who have very dark skin, those on statin medication, those on a poor diet, those confined to hospitals or nursing homes and others who mistakenly believe the sun is evil, will never get enough vitamin D.
Vitamin D is fat-soluble, meaning that if we get plenty one day and miss the sun for a few days, we will still be able to call on our vitamin D reserves stored in fat cells.
Of course, UV-B will still damage our skin if we stay out in the sun too long.
UV-C
UV-C rarely gets to Earth as it is almost completely absorbed in the atmosphere, so is of little concern unless you are an astronaut.

Why we NEED sunlight, more than just for Vitamin D3

The human body is designed to thrive in sunlight, and it is not only the Vitamin D3 benefit.
A 20-year study of over 29,000 people found that those avoiding sun exposure had double the death rate from all causes!
This study did not measure D3 levels, but results from other D3 studies show that the high death rate from insufficient sun exposure can not be accounted for only by low Vitamin D3.

We also get Cholesterol Sulfate from sunlight on the skin.
Cholesterol sulfate protects red blood cells from breaking up. Without enough cholesterol sulfate, we get a condition called hemolysis, where the red blood cells die prematurely, spilling their contents into the blood.
Without sulfur, and without the sun, we cannot make cholesterol sulfate, a molecule which is both fat-soluble and water soluble, which is essential for the body to distribute cholesterol and sulfur throughout the body.
All artery walls have an endothelial lining, and these endothelial cells cannot work correctly when depleted in sulfate. They cannot control what gets into and out of cells, which promotes cardiovascular plaque.
Cholesterol Sulfate, in conjunction with it’s nitric sister, eNOS, determines how thick or thin or blood becomes. Sulfate makes it thicker, nitric makes it thinner, and this automatic regulatory system works very well as long as we have supplies of both, for which we need sunlight.
Interestingly, one thing that messes up these molecules is glyphosate (“Roundup” and other weedkiller trade names) so this is a good reason to avoid all GM (Genetically Modified) foods, which are all heavily sprayed with glyphosate.
Sulfur is incredibly important for health. Cholesterol sulfate protects against bacterial and virus infections and strengthens the immune system.
Cholesterol sulfate is essential for babies. Women normally have about 1.5 units of cholesterol sulfate in the blood, but in pregnancy, levels rise in the villi of the placenta to around 24 units!
Foods high in sulfur include eggs, beef, garlic, onions, sprouts, asparagus, kale, coconut oil, olive oil, but only where they are grown or raised in sulfur-rich soil (think organic).

Vitamin D sulfate is also made from sunlight, and is both water and fat soluble, so it can go anywhere in the body, distinct from the regular fat-soluble Vitamin D3 I have been talking about. Same with cholesterol sulfate. Not only is it both water and fat soluble, it can travel through the body on it’s own, where many other substances need to be “carried” by cholesterol wherever they need to go.
If we want healthy blood, we MUST have sunlight!
Humans make several other important peptide and hormone “photoproducts” when skin is exposed to UVB sunlight:

  • β-Endorphins are natural opiates that induce relaxation and increase pain tolerance
  • Calcitonin Gene-Related Peptides are vasodilators (expand blood vessels) that protect us from hypertension (blood pressure), vascular inflammation, and oxidative stress
  • Substance P is a neuropeptide that increases blood flow and also regulates immune system response to acute stressors
  • Adrenocorticotropic Hormone is a polypeptide hormone, controlling cortisol (stress hormone) release by the adrenal glands, regulating immune system and inflammation
  • Melanocyte-Stimulating Hormone is a polypeptide hormone, reducing appetite, increasing libido, and increasing skin pigmentation

Sunlight contains a beneficial EMF (electromagnetic frequency) that is essential for health.
40% of sunlight is infrared, and the red and near-infrared frequencies interact with CCO (Cytochrome C Oxidase). CCO is a protein in the inner mitochondrial membrane, also part of the electron transport chain. CCO is a chromophore (a molecule that attracts and absorbs light), so sunlight improves ATP (the generation of energy). The optimal wavelengths for CCO are red at 630 nm to 660 nm (nanometers) and near-infrared at 810 nm to 850 nm.
LeanMachine gets sun exposure as often as possible. Others afraid of the sun may consider photobiomodulation therapy (use of near-infrared light treatment).
UVA exposure is generally considered harmful, as this is the most damaging kind of exposure for skin with no ability to generate Vitamin D, however there are benefits such as releasing NO (Nitric Oxide), discussed above. An important cellular signaling molecule that dilates blood vessels and reduces blood pressure.
This is closely tied to another molecule, eNOS (endothelial nitric oxide synthase) which regulates the “thickness” of blood. When blood becomes too thick, eNOS makes more nitric oxide which expands blood vessels and thins the blood. When blood is too thin, eNOS makes more sulfate. Sulfate is essential for the endothelial lining of all blood vessel walls. If we are low in sulfate, the wall can start breaking down and clots start to form to repair the damage. We can get more sulfur in the diet from onions, garlic, broccoli, egg yolks and other foods, or by supplements such as MSM (MethylSulfonoyl Methane) but we still need sunlight to make cholesterol sulfate which can be distributed through the body to keep us alive!

Apart from photoproducts, nitric oxide and cholesterol sulfate production, sunlight is essential for our circadian rhythm (body clock). Sunshine activates neurons in the suprachiasmatic nucleus of the hypothalamus, sending signals to the pineal gland which regulates production of the hormone melatonin. When the circadian rhythm is upset, melatonin and other hormone production is disrupted, leading to mood problems, poor cognition (thinking), metabolic syndrome (leads to diabetes) and increased risk of cancer.

Tanning Beds

Tanning beds are famous for increasing risk of melanomas, the most deadly form of skin cancer.
Tanning beds have been outlawed in all States of Australia, except in the Northern Territory, where they are still legal, but there are no commercial solariums there because the tropical climate makes sunlight tanning easy. However, this is seen by some as a knee-jerk reaction by politicians to win votes.
Most tanning beds produce UV-A and UV-B radiation, but some better units are available which produce only UV-B, which are much safer if used correctly.
Staying too long in even a quality tanning bed will cause skin damage, a precursor to many forms of skin cancer. Tanning beds that emit high levels of UV-A should be avoided completely.

Vitamin D3 from food

We get some vitamin D from the diet. Eggs, fish, cod liver oil are all good sources, and also come naturally with Vitamin A, but it is almost impossible to get enough D3 from the diet, so we must top up our D3 from sunlight or supplements or both. Milk contains some vitamin D, but calcium and vitamin D in milk are very poorly absorbed. Asian women are more likely than white women to be diagnosed with osteoporosis, so doctors claim this is caused by low milk consumption, but Asian women are much less likely to have a hip fracture (the worst kind), indicating that traditional DEXA scans (bone density tests) do not mean much, as dense bones are often not as strong as less dense but more flexible bones.
Africans generally have stronger bones than caucasians, even though they get less vitamin D3 from sunlight. They appear to be much more sensitive to the sunlight they do receive.

VitaminD3 from supplements

Most Vitamin D3 sold in Australia from chemist shops or supermarkets contain 1000 IU which may be enough to prevent rickets in young people, but is nowhere near optimum for immunity and bone strength, especially in older people, and not enough for anyone except small children to have an optimal immune system.
LeanMachine recommends Vitamin D3 5000 IU daily for almost a year’s supply, and this is the cheapest health insurance anyone can buy!
Vitamin K2 is also recommended, as this combination helps put calcium where it belongs, in bones and teeth, and reduces calcium buildup in blood vessels (arterial plaque).
Vitamin A is also recommended for health benefits as well as to eliminate any chance of toxicity.

No Cholesterol means no Vitamin D3

As explained above, cholesterol is the building-block for vitamin D3, also for every hormone in the body and many other functions.
About half the adult population over 60 in Australia and the USA is taking statin medication.
Sold under many names including Simvastatin, Lipitor, Advicor, Lovastatin, Mevacor, Vytorin, Zocor, Lipex, Simcor, Crestor, Pitavastatin, Pravastatin, Rosuvastatin, Fluvastatin, and Cerivastatin (withdrawn 2001).

The Lies about Cholesterol

Statins do lower cholesterol, but we NEED cholesterol, it is NOT the enemy it is made out to be. Yes, cholesterol is found in a badly inflamed body, but this is because the liver makes more cholesterol to repair damage caused by the inflammation, which is the REAL cause of poor health.
Statins reduce cholesterol by preventing the liver from producing as much cholesterol, but the job of the liver is to make cholesterol as required.
If we eat cholesterol foods (such as meat or eggs) the liver makes less, if we eat no cholesterol (such as a vegan diet), the liver makes more, which is the way it should be.
When statins are used, they attempt to shut down this natural process, and in so doing, also shuts down co-enzyme Q10 which is vital for healthy muscles.
And the heart is the most important muscle in the body – why clobber it with statins?
Statins also stop production of 7-dehydrocholesterol, so then we get almost zero vitamin D3 from sunlight.
Statins have shown no benefit to women whatsoever in many studies.
For men who have had a heart attack, statins have shown a slight reduction in deaths from future heart attacks, but in all patients, statins cause an INCREASE in deaths from all other causes!
Because statins knock out our Co-enzyme Q10 (often called the spark-plug for the heart), the patient can suffer extensive muscle damage, causing pain, reduced mobility and even death.
Drug companies say they have no idea what causes this increase in death from statins, but the answer is obvious to me – low vitamin D3!
Studies show that treatment with one fish oil capsule daily prevented 9% of deaths in cardiac patients over 4 years, while those given the Crestor statin drug had an INCREASED death rate of 1% over the same period.
The Framingham study, the biggest and longest study ever, showed that those with the lowest cholesterol died first, and those with the highest cholesteol lived longest!
But the drug companies continue to perpetuate these cholesterol lies to maximise profits from their biggest-selling drug.

How much D3 do we need?

The older we get, the more vitamin Vitamin D3 we need.
The only way to know how much we have is by a blood test, because ethnic background, skin colour, amount of tan, food, medication, supplements, geographic location, sun exposure, clothing, sunscreen, exercise, BMI and many other factors determine how much Vitamin D3 we absorb and retain.
Vitamin D3 is a fat-soluble vitamin, so daily levels do not vary much, as every fat cell in the body can store D3.
Always ask the doctor for a printed copy of your results so you can compare with any previous test and also get a true reading.
Unfortunately, most Australian labs say we need 60 to 160 nmol/L of D3, which is inadequate. Better labs say 75 nmol/L is the minimum, but we need more.
Values above 60 will prevent us from getting rickets, but will not give us good immunity.
For optimal immune system function, we should aim for the high end of the range of 125 to 175 nmol/L.
If we are battling cancer or some other serious disease, we should aim for 175 to 250 nmol/L but this requires careful monitoring and extra Vitamin K2 and Vitamin A to prevent toxicity.
Supplement values vary, and the RDA (recommended Daily Allowance) of 60 IU was alarmingly too low, and changed to 400 IU, originally determined as the minimum amount to prevent rickets.
Even the 400 IU allowance typically gives a blood test of 40 to 60 nmol/L which may barely stop rickets but will not provide a strong immune system.
Conservative studies determine that infants less than one year old need 400 IU daily, 1 year to adolescents need 400-600 IU daily, adults need 400-600 IU daily, and adults aged over 70 years need 400-800 IU daily.
More modern studies recommend babies take 400 IU, children 1000 IU, adults 4000 IU, and those over 70 may need 8000 IU daily.
Small doses are fine for strong bones, but for a strong immune system to ward off all disease, high doses are a must.
LeanMachine has taken 5000 IU daily for over 10 years, and has zero colds, flu or any other illness, not even a headache!

But don’t I get my Vitamin D3 from Milk?

Sorry, but you do not!
I was told to drink milk as a youngster, some 6 decades ago, and milk does indeed contain vitamin D and calcium, but these and other nutrients in milk are poorly absorbed in the gut.
Worse, pasteurised milk has most of the nutrients heated out of it, and homogenisation is very BAD for our health.
Homogenisation is a process making each fat globule 10 times smaller than normal, to save us the trouble of shaking the milk container to disperse the cream. The problem then is that these tiny fat globules then enter the bloodstream through imperfections in the gut lining, often referred to as “leaky gut syndrome”. When raw milk fat enters the blood directly like this, the immune system detects this as a foreign substance, and begins attacking these fat globules, and marks them as invaders. Now when we consume milk the regular way, and absorb it naturally through a healthy intestine, the immune system starts attacking this as well, as it has already been recognised as a foreign invader. The result: Allergies to Lactose, one of the main ingredients in milk, has reached epidemic proportions in the last few decades where homogenisation has become standard practice. Vitamin D3 can help stabilise an over-reactive immune system, but the only safe way to drink milk is to only use NON-HOMOGENISED milk. Most supermarkets have it, but you have to look past the big-name brands to find it.
In many countries it is against the law to buy non-pasteurised milk, but we can at least buy non-homogenised milk if we feel we must have milk (and we do not need milk).
Some Asian countries have diets where milk is non-existent, and their bones are stronger, and broken bones are rare.
We get more useful Vitamin D3 from broccoli and other fresh vegetables than from milk!
Milk is also BAD for our bones, as it is acid-forming in the body, and all acids in the blood cause an immediate reaction in the body to neutralise the blood acid (otherwise we die!).
This reaction, controlled by the parathyroid glands, leaches potassium, calcium and magnesium from bones, teeth and organs, the fastest way the body can neutralise the acid.
If we must drink milk (and we do not have to for a healthy diet) then the ONLY milk to buy is FULL CREAM, UNHOMOGENISED milk, which you can find at good supermarkets if you look hard enough.
The only better product is the milk straight from the cow, or better still straight from mother’s breast (most mothers will not be impressed if you ask for milk this way!)

Getting enough of the right Vitamin D3

Sunlight is still the best way to get enough Vitamin D3 and Cholesterol Sulfate, but for many, this can be difficult or impossible.
Supplements are the next best choice, but the supplements we buy at Chemist shops or supermarkets in Australia have only around 1000 IU of Vitamin D3.
They are also often combined with Calcium, which LeanMachine does NOT recommend, but that is another story.
While this is better than nothing, most people require 5 to 10 times this much to bring their levels to “optimum”.
For most health specialists, “optimum” means over 60 or 75 nmol/l (30 ng/ml), and if your results come in at over this threshold, the doctor will say you are fine.
However, true experts in this field say that truly optimum for a normal healthy person for immunity to disease, is between 125 and 175 nmol/L (50 – 70 ng/ml).
For those recovering from a serious disease, optimum should be 175 to 250 nmol/L (70 – 100 ng/ml).
Vitamin D3 can be toxic at high doses for extended periods, so continuous levels over 250 nmol/L (100 ng/ml) should be avoided.
Blood tests are advised for all very high-dosage patients.
People most at risk of deficiency are the elderly, those with with dark skin, those who cover their body with clothing or sun screen, or work night shifts or underground and never see the light of day, and those who live furthest from the equator or in cloudy climates.
Those at risk may need 10,000IU daily supplements, the rest of us can usually get plenty with 5000IU, and the very young who get plenty of sunlight on a regular basis may not require any.
Remember that we only get Vitamin D3 from sun in a blue sky when the sun is high, from the UVB (Ultra-Violet light in the “B” range”).
When the sun is low in the sky, or when there is cloud, or when the light comes through a glass window, UVB is blocked and we only receive UV-A which is the damaging, cancer-causing radiation with Zero Vitamin D3 benefits.
Other tests: Depending on the condition, the doctor may order other tests to check for liver and kidney disease as well as a full blood count.
A full blood test for Vitamin D3 is:
25-hydroxyvitamin-D (25-D or D2/D3) or 25(OH)D or simply 25-D
1,25-dihydroxyvitamin-D3, or 1,25(OH)2 D3, or 1,25 2(OH), or simply 1,25-D
Most doctors will only test for 25(OH)D which is the storage form, which is fine for most people.
For those suspected of having Sarcoidosis (a rare condition) then both must be tested, and vitamin D supplementation and sunlight should be avoided altogether unless the active form 1,25(OH)2 is tested low.

Vaccinations

There are many reports of children suffering from Autism and other serious conditions after vaccinations.
Vitamin D3 supplements should be taken for at least 1 week before any vaccination to reduce risk of unfortunate reactions.
Panadol, Panadeine, Paracetamol, Tylenol, Acetaminophen, Atasol, etc must NEVER be taken before or after any vaccination, even though doctors incorrectly recommend it to reduce pain and fever.
Autism rates in the USA are 1 in 45, while Autism rates in Cuba are 1 in 12,000.
A few decades ago, Austism rates were only around 1 in 200, before Panadol (Tylenol, Acetaminophen in the USA)
Cuba has a high vaccination rate of 97%, but the difference:
These over-the counter pain medications are prescription-only items in Cuba.
Of course, no drug company is interested in conducting a study where the result may be that their “safe and effective” product causes Autism, but as far as LeanMachine is concerned, Vitamin D3 reduces the risk of sickness from almost any disease.
Besides Autism, Panadol can destroy liver function (most patients on the liver transplant waiting list are there because of Panadol), and Panadol is also acted upon by enzymes which then destroy the body’s reserves of L-Glutathione, the natural “Master Antioxidant” in the body.
If you want your child vaccinated anyway, DO give them vitamin D3 and DO NOT give them any pain or fever medication.
A little fever is the body’s way to fight the toxins in the vaccination and the best way to deal with it is to let it run it’s course.
However, a very high fever can lead to convulsions, especially in small children. The best way to bring down a very high fever is to place the child in a cool to lukewarm bath and keep water over the skin using a sponge or cloth.
No drugs required, and much safer and more effective than any drug.
Better still, vaccinations can be avoided altogether for those with a strong immune system.
For more information on vaccinations, see this article: Vaccinations.

Autoimmune conditions

Allergies, hives, arthritis, lupus, psoriasis, rheumatoid arthritis, thyroid disease, multiple sclerosis, etc, are all autoimmune conditions.
Little help is available from medications which merely help to ease symptoms.
Vitamin D3 builds the immune system and protects us from colds, flu and other diseases, but Vitamin D3 is also an Immune Moderator, helping to dampen the effect of the immune system over-reacting, the cause of auto-immune disease.
Vitamin D3 can also help treat the cause of the symptoms, often Helicobacter pylori (H. pylori), found in over 70% of autoimmune patients.
H. pylori can invade the gut via contaminated water or food, or from contact with infected people or animals, causing gut inflammation, disrupting the immune system.
Vitamin D3 effectively destroys H. pylori and restores the immune system, often reducing allergy symptoms by 30% in seven days, and another 40% in 12 weeks.
H. pylori infects around 30% of adults in the western world, more if we are over 60 with low Vitamin D3 levels.
A blood test can give your D3 levels, but the lab will say 60 to 75 nmol/L is OK, but we need 125 nmol/L minimum to destroy H. pylori.
Mushrooms, eggs, wild-caught salmon, etc have natural Vitamin D3 but the modern Western diet is lacking in these. Mushrooms grown in the dark will have no vitamin D3, but 30 minutes of exposure to direct sunlight can generate significant D3 levels.

Vitamin D3
The latest science Says: “It’s not just about bones, it’s about your total well-being!
Professor Michael Holick:
We now think that maintaining adequate Vitamin D3 levels are important for decreasing the risk of prostate cancer, breast cancer and colon cancer.
There is some evidence that in young children if they are fortified with vitamin D3 from 12 months old it can reduce the risk of type 1 diabetes by 80%“.
Professor Philip Sambrook:
We have always thought it could not happen in Australia – it is too sunny a country. However, people do not get sunlight for various reasons and if you do not get some sunlight you do not make vitamin D3. We do not get it much in food any more so for that reason, deficiency is quite common. And the vitamin protects healthy cells while also killing cancer cells.”

LeanMachine online supplements

Note: This online supplement shop is now closed, but each product page contains a link to the best supplier of that product.

Disclaimer

LeanMachine is not a doctor, and everyone should consult with their own health professional before taking any product to ensure there is no conflict with existing prescription medication.
LeanMachine has been researching nutrition and health since 2010 and has completed many relevant studies including:

  • Open2Study, Australia – Food, Nutrition and Your Health
  • RMIT University, Australia – Foundations of Psychology
  • Swinburne University of Technology, Australia – Chemistry – Building Blocks of the
  • World
  • University of Washington, USA – Energy, Diet and Weight
  • Johns Hopkins Bloomberg School of Public Health, USA – Health Issues for Aging
  • Populations
  • Johns Hopkins Bloomberg School of Public Health, USA – International Nutrition
  • Johns Hopkins Bloomberg School of Public Health, USA – Methods in Biostatistics I
  • Johns Hopkins Bloomberg School of Public Health, USA – Methods in Biostatistics II
  • Johns Hopkins Bloomberg School of Public Health, USA – Principles of Human Nutrition
  • TUFTS University, USA – Nutrition and Medicine
  • TUFTS University, USA – Lipids/Cardiovascular Disease I and Lipids/Cardiovascular Disease II
  • Technical Learning College, USA – Western Herbology, Identification, Formulas
  • Bath University, England – Inside Cancer
  • WebMD Education – The Link Between Stroke and Atrial Fibrillation
  • WebMD Education – High Potassium: Causes and Reasons to Treat
  • Leiden University Medical Center, Netherlands – Anatomy of the Abdomen and Pelvis
  • MIT (Massachusetts Institute of Technology) – A Clinical Approach to the Human Brain

LeanMachine has now examined thousands of studies, journals and reports related to health and nutrition and this research is ongoing.

Updated 11th January 2020, Copyright © 1999-2020 Brenton Wight and BJ&HJ Wight trading as Lean Machine abn 55293601285

Cholesterol does not cause heart disease

Analysis by Dr. Joseph Mercola Fact Checked July 24, 2019
Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2019/07/24/cholesterol-myth-what-really-causes-heart-disease.aspx
cholesterol myth what really causes heart disease

Story at-a-glance

  • A 2018 scientific review presents substantial evidence that high LDL and total cholesterol are not an indication of heart disease risk, and that statin treatment is of doubtful benefit as a form of primary prevention for this reason
  • Three recent reviews that supported the cholesterol hypothesis were found to have misrepresented data and findings of previous studies to support their own conclusions
  • Overall, the analysis found the association between total cholesterol and CVD is weak, absent or inverse in many studies
  • Older people with high LDL do not die prematurely — they actually live the longest, outliving both those with untreated low LDL and those on statin treatment
  • A 2015 meta-analysis of 11 statin drug studies found statin use postponed death by a mere 3.2 days in primary prevention trials and 4.1 days in secondary prevention trials

For the past six decades, the U.S. dietary advice has warned against eating cholesterol-rich foods, claiming dietary cholesterol promotes arterial plaque formation that leads to heart disease. We now have overwhelming evidence to the contrary, yet dogmatic thinking can be persistent, to say the least.

After decades’ worth of research failed to demonstrate a correlation between dietary cholesterol and heart disease, the 2015-2020 Dietary Guidelines for Americans1,2 finally addressed this scientific shortcoming, announcing “cholesterol is not considered a nutrient of concern for overconsumption.”

To this day, the evidence keeps mounting, showing there’s no link between the two. Similarly, the evidence supporting the use of cholesterol-lowering statin drugs to lower your risk of heart disease is slim to none, and is likely little more than the manufactured work of statin makers — at least that’s the implied conclusion of a scientific review3 published in the Expert Review of Clinical Pharmacology in 2018.

Cholesterol myth kept alive by statin advocates?

The 2018 review4 identified significant flaws in three recent studies “published by statin advocates” attempting “to validate the current dogma.” The paper presents substantial evidence that total cholesterol and low-density lipoprotein (LDL) cholesterol levels are not an indication of heart disease risk, and that statin treatment is of “doubtful benefit” as a form of primary prevention for this reason. According to the authors:5

“According to the British-Austrian philosopher Karl Popper, a theory in the empirical sciences can never be proven, but it can be shown to be false. If it cannot be falsified, it is not a scientific hypothesis. In the following, we have followed Popper’s principle to see whether it is possible to falsify the cholesterol hypothesis.

We have also assessed whether the conclusions from three recent reviews by its supporters are based on an accurate and comprehensive review of the research on lipids and cardiovascular disease (CVD) …

Our search for falsifications of the cholesterol hypothesis confirms that it is unable to satisfy any of the Bradford Hill criteria for causality and that the conclusions of the authors of the three reviews are based on misleading statistics, exclusion of unsuccessful trials and by ignoring numerous contradictory observations.”

As reported by Reason.com:6

“A comprehensive new study on cholesterol, based on results from more than a million patients, could help upend decades of government advice about diet, nutrition, health, prevention, and medication …

The study … centers on statins, a class of drugs used to lower levels of LDL-C, the so-called ‘bad’ cholesterol, in the human body. According to the study, statins are pointless for most people …

The study also reports that ‘heart attack patients were shown to have lower than normal cholesterol levels of LDL-C’ and that older people with higher levels of bad cholesterol tend to live longer than those with lower levels.

No evidence cholesterol influences heart disease risk

Indeed, the authors of the Expert Review of Clinical Pharmacology analysis point out that were high total cholesterol in fact a major cause of atherosclerosis, “there should be exposure-response in cholesterol-lowering drug trials.”7 In other words, patients whose total cholesterol is lowered the most should also see the greatest benefit. Alas, that’s not the case.

A review of 16 relevant cholesterol-lowering trials (studies in which exposure-response was actually calculated), showed this kind of exposure-response was not detected in 15 of them. What’s more, the researchers point out that the only study8 showing a positive exposure-response to lowered cholesterol used exercise-only as the treatment.

Patients with high total cholesterol should also be at increased risk of death from CVD, but the researchers found no evidence of this either, not-so-subtly pointing out that this is “an idea supported by fraudulent reviews of the literature.” They provide the following example of how research has been misrepresented:9

“The hypothesis that high TC [total cholesterol] causes CVD was introduced in the 1960s by the authors of the Framingham Heart Study. However, in their 30-year follow-up study published in 1987, the authors reported that ‘For each 1 mg/dl drop in TC per year, there was an eleven percent increase in coronary and total mortality’.

Three years later, the American Heart Association and the U.S. National Heart, Lung and Blood Institute published a joint summary concluding, ‘a one percent reduction in an individual’s TC results in an approximate two percent reduction in CHD risk’. The authors fraudulently referred to the Framingham publication to support this widely quoted false conclusion.”

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Contradictory findings routinely ignored or misrepresented

To determine whether the three reviews under analysis had misrepresented previous findings, they scoured the three papers for quotations from 12 studies reporting results “discordant with the cholesterol hypothesis.” Only one of the three reviews had quoted articles correctly, and even then, only two of the dozen studies were quoted correctly.10

“About half of the contradictory articles were ignored. In the rest, statistically nonsignificant findings in favor of the cholesterol hypothesis were inflated, and unsupportive results were quoted as if they were supportive. Only one of the six randomized cholesterol-lowering trials with a negative outcome was cited and only in one of the reviews.”

The researchers also highlight a large meta-analysis that simply ignored “at least a dozen studies” in which no or inverse association was shown. Overall, the Expert Review of Clinical Pharmacology analysis found that “the association between total cholesterol and CVD is weak, absent or inverse in many studies.”

No link between LDL and heart disease either

The Expert Review of Clinical Pharmacology paper11 also tears apart claims that high LDL causes atherosclerosis and/or CVD. Just as with total cholesterol, if high LDL was in fact responsible for atherosclerosis, then patients with high LDL would be diagnosed with atherosclerosis more frequently, yet they’re not, and those with the highest levels would have the greatest severity of atherosclerosis, yet they don’t.

The researchers cite studies showing “no association” between LDL and coronary calcification or degree of atherosclerosis. Ditto for LDL and CVD. In fact, a study looking at nearly 140,000 patients with acute myocardial infarction found them to have lower than normal LDL at the time of admission.

Even more telling, another study, which had originally reported similar findings, still went ahead and lowered the patients’ LDL even more. At follow-up three years later, they discovered that patients with an LDL level below 105 mg/dl (2 mmol/L) had double the mortality rate of those with higher LDL.12

Interestingly, the authors suggest this inverse relationship may be due to low LDL increasing your risk for infectious diseases and cancer, both of which are common killers.

They also review evidence showing older people with high LDL do not die prematurely — they actually live the longest, outliving both those with untreated low LDL and those on statin treatment. One such study13,14 — a meta-analysis of 19 studies — found 92% of individuals with high cholesterol lived longer.

Benefits of statin treatment are overblown

Lastly, the Expert Review of Clinical Pharmacology paper analyzes statin claims, showing how studies exaggerate benefits through a variety of different tactics. Again, in some cases, by simply excluding unsuccessful trials.

“Furthermore, the most important outcome — an increase of life expectancy — has never been mentioned in any cholesterol-lowering trial, but as calculated recently by Kristensen et al.,15 statin treatment does not prolong lifespan by more than an average of a few days,” the authors state.16

Indeed, the study they’re referring to, published in BMJ Open in 2015, which looked at 11 studies with a follow-up between two and 6.1 years, found “Death was postponed between -5 and 19 days in primary prevention trials and between -10 and 27 days in secondary prevention trials.” The median postponement of death in primary prevention trials was 3.2 days, and in secondary prevention trials 4.1 days!

Considering the well-documented health risks associated with statins, this is a mind-bending finding that really should upend the dogma. And yet, the dogma remains, and may even strengthen in coming days.

JAMA editorial calls for end to ‘fake news’ about statins

The cholesterol myth has been a boon to the pharmaceutical industry, as cholesterol-lowering statins — often prescribed as a primary prevention against heart attack and stroke — have become one of the most frequently used drugs on the market. In 2012-2013, 27.8% of American adults over the age of 40 reported using a statin, up from 17.9% a decade earlier.17,18 But that was six years ago, I suspect over a third of adults over the age of 40 are now using statins.

In addition to the BMJ Open study cited above, an evidence report19 by the U.S. Preventive Services Task Force, published November 2016 in JAMA, found 250 people need to take a statin for one to six years to prevent a single death from any cause; 233 had to take a statin for two to six years to prevent a single cardiovascular death specifically. To prevent a single cardiovascular event in people younger than 70, 94 individuals would have to take a statin.

As noted in a 2015 report,20 “statistical deception created the appearance that statins are safe and effective in primary and secondary prevention of cardiovascular disease.” The paper points out that by using a statistical tool known as relative risk reduction, the trivial benefits of statins appear greatly amplified.

Scientific findings such as these are the core reason why statins are given negative press. However, we may soon see a reversal in the news cycle, with negative statin articles being tagged as “fake news.”

According to a June 2019 editorial21 in JAMA Cardiology, written by cardiologist Ann Marie Navar,22 statins are the victim of “fear-based medical information,” just like vaccines, and this is what’s driving patient nonadherence. Cardiovascular Business reported:23

“We know that what people read influences their actions, Navar said, and indeed, one 2016 study in the European Heart Journal found that on a population level, statin discontinuation increased after negative news stories about statins surfaced in those communities.

In another study, more than one in three heart patients said they declined a statin prescription solely for fears of adverse effects. ‘Measles outbreaks are highly visible: a rash appears, public health agencies respond, headlines are made and the medical community responds vocally,’ Navar wrote.

‘In contrast, when a patient who has refused a statin because of concerns stoked by false information has an MI, the result is less visible. Nevertheless, cardiologists and primary care physicians observe the smoldering outbreak of statin refusal daily.’”

Cardiovascular Business summarizes Navar’s suggestions for how doctors can fight back against false information about statins and build adherence, such as handing out yearlong prescriptions with automatic refills.24

When I first wrote about the censorship of anti-vaccine material occurring on every single online platform, I warned that this censorship would not stop at vaccines. And here we’re already seeing the call for censoring anti-statin information by glibly labeling it all “fake news.”

Chances are, the censoring of anti-statin information is already underway. A quick Google search for “statin side effects” garnered pages worth of links talking about minor risks, the benefits of statins, comparison articles, looking at two different brands — in other words, mostly positive news.

The scientific fact is, aside from being a “waste of time” and not doing anything to reduce mortality, statins also come with a long list of potential side effects and clinical challenges, including:

An increased risk for diabetes
Decreased heart function25
Nutrient depletions — Including CoQ10 and vitamin K2, both of which are important for cardiovascular and heart health
Impaired fertility — Importantly, statins are a Category X medication,26 meaning they cause serious birth defects,27 so they should never be used by a pregnant woman or women planning a pregnancy
Increased risk of cancer — Long-term statin use (10 years or longer) more than doubles women’s risk of two major types of breast cancer: invasive ductal carcinoma and invasive lobular carcinoma28
Nerve damage — Research has shown statin treatment lasting longer than two years causes “definite damage to peripheral nerves”29

How to assess your heart disease risk

 

cholesterol levels

As a general rule, cholesterol-lowering drugs are not required or prudent for the majority of people — especially if both high cholesterol and longevity run in your family. Remember, the evidence overwhelmingly suggests your overall cholesterol level has little to nothing to do with your risk for heart disease.For more information about cholesterol and what the different levels mean, take a look at the infographic above. You can also learn more about the benefits of cholesterol, and why you don’t want your level to be too low, in “Cholesterol Plays Key Role in Cell Signaling.” As for evaluating your heart disease risk, the following tests will provide you with a more accurate picture of your risk:

HDL/Cholesterol ratio — HDL percentage is a very potent heart disease risk factor. Just divide your HDL level by your total cholesterol. That percentage should ideally be above 24%.
Triglyceride/HDL ratio — You can also do the same thing with your triglycerides and HDL ratio. That percentage should be below 2.
NMR LipoProfile Large LDL particles do not appear to be harmful. Only small dense LDL particles can potentially be a problem, as they can squeeze through the lining of your arteries. If they oxidize, they can cause damage and inflammation.

Some groups, such as the National Lipid Association, are now starting to shift the focus toward LDL particle number instead of total and LDL cholesterol to better assess your heart disease risk. Once you know your particle size numbers, you and your doctor can develop a more customized program to help manage your risk.

Your fasting insulin level — Heart disease is primarily rooted in insulin resistance,30 which is the result of a high-sugar diet. Sugar, not cholesterol or saturated fat, is the primary driver. Clinical trials have shown high fructose corn syrup can trigger risk factors for cardiovascular disease within as little as two weeks.31

Any meal or snack high in carbohydrates like fructose and refined grains generates a rapid rise in blood glucose and then insulin to compensate for the rise in blood sugar.

The insulin released from eating too many carbs promotes fat accumulation and makes it more difficult for your body to shed excess weight. Excess fat, particularly around your belly, is one of the major contributors to heart disease.

Your fasting blood sugar level — Research has shown people with a fasting blood sugar level of 100 to 125 mg/dl have a nearly 300% increased higher risk of coronary heart disease than people with a level below 79 mg/dl.32,33
Your iron level — Iron can be a very potent oxidative stress, so if you have excess iron levels you can damage your blood vessels and increase your risk of heart disease. Ideally, you should monitor your ferritin levels and make sure they are not much above 80 ng/ml.

The simplest way to lower them if they are elevated is to donate your blood. If that is not possible you can have a therapeutic phlebotomy and that will effectively eliminate the excess iron from your body.

How to diminish, dissolve and reverse arterial plaque

Re-posted from original article: www.naturalhealth365.com/plaque-atherosclerosis-3037.html

How to diminish, dissolve and reverse arterial plaque(NaturalHealth365) As you probably know, it’s not cancer, Alzheimer’s disease, diabetes or auto accidents that make ups the conditions most likely to threaten the lives of American adults – it’s cardiovascular disease.  In fact, according to statistics published by the CDC, heart disease currently kills nearly 650,000 people – every year – in the United States.  And a primary factor in heart disease is arterial plaque – artery-clogging deposits of fat and calcium that can lead to angina, heart attack and stroke.

The grim figures on the consequences of arterial plaque – also known as atherosclerosis – continue to accumulate.  Every year, about 735,000 Americans experience a heart attack, while another 795,000 suffer a stroke.  Isn’t it time to learn how to reduce your odds – and prolong your life?

Breaking NEWS about plaque: Doctors don’t want you to know this truth about heart disease

Unlike most other animals, humans (along with primates, bats and guinea pigs) lack the ability to produce vitamin C in the body – a condition that is due to a long-ago genetic variation.  This means that vitamin C must be obtained through dietary means – and the consequences for failing to consume sufficient amounts can be dire.

According to the Pauling/Rath Unified Theory of Cardiovascular Disease – a theory developed by Nobel Prize-winning scientist Dr. Linus Pauling, in conjunction with German doctor Mathias Rath – the lion’s share of cardiovascular problems are really caused by shortages in vitamin C.

Having insufficient levels of this indispensable nutrient causes arteries to become brittle and vulnerable to cracks and fissures.  In addition, vitamin C shortages can elevate cholesterol levels – particularly that of lipoprotein A or Lp(a), a type of LDL cholesterol with “sticky,” adhesive qualities.

Lp(a) is believed to be the primary culprit in the formation of arterial plaque and the constriction of arteries.  This belief was reinforced in 1989, when researchers evaluating the clogged aortas of heart attack victims noted that they were finding only the Lp(a) type of cholesterol in the deposits.

Do NOT ignore the health dangers linked to toxic indoor air.  These chemicals – the ‘off-gassing’ of paints, mattresses, carpets and other home/office building materials – increase your risk of headaches, dementia, heart disease and cancer.

As arteries develop ruptures, the body attempts to repair the damage by sending cholesterol to the site.

But the “down side” is that this reparative cholesterol begins to accumulate and form plaque deposits, inhibiting the flow of oxygen-rich blood and triggering strokes and heart attacks.

Simple, yet revolutionary, these natural nutrients help to REDUCE the risk of plaque buildup

The key to preventing and treating heart disease, as set forth in the Pauling Therapy, is the administration of high doses of vitamin C, along with the amino acid lysine.

High doses of vitamin C serve to strengthen arteries and make them less susceptible to breakage, while supplementary lysine can stop Lp(a) from sticking to artery walls.  A later protocol developed by Dr. Rath calls for the addition of the amino acid proline.

Like lysine, proline can act as a sort of ‘teflon’ in the arteries, discouraging sticky Lp(a) and promoting better circulation of blood.  When given in sufficient dosages, this therapy can inhibit formation of atherosclerotic deposits – and even help to remove and dissolve existing plaques.

Proponents of the Pauling Therapy maintain that the protocol can also lower cholesterol, relieve the pain of angina pectoris, increase heart strength, improve natural immunity and promote overall health.

Address and prevent heart disease with simple lifestyle and dietary recommendations

According to Dr. Pauling, every person at risk for heart disease should take at least 5 g (5,000 mg) of vitamin C and at least 2 grams of lysine a day.

To address atherosclerosis, Dr. Pauling recommended daily dosages of 6,000 to 18,000 mg of vitamin C in divided doses, along with 2,000 to 6,000 mg of lysine.

Enhancements to the protocol can include 800 IU a day of vitamin E – which helps to make blood less “sticky” and likely to clot – and 100 to 300 mg a day of coenzyme Q10 – which helps the heart to pump blood more efficiently.

Note: it is particularly important to supplement with CoQ10 if you take statin medications to lower cholesterol. These can deplete the body’s store of this important nutrient.

The amino acids carnitine, taurine and arginine also benefit heart function, while vitamin K – found in leafy greens – has antioxidant properties and can help slow the deposit of plaque.  Note: if you are taking anticoagulant medication, talk to your medical doctor before consuming any food or supplement with vitamin K.

And supplementary DHEA – a hormone created naturally in the body – has been linked with reductions in atherosclerosis and clogged arteries, along with decreased mortality from heart disease.

Bonus health tip: DHEA can lower levels of disease-promoting inflammation, and can even help protect against the formation of harmful visceral fat around the abdomen.

As always, consult with a trusted integrative healthcare provider before trying the Pauling Therapy – or adding any supplements to your diet.  And, never reduce or eliminated prescribed heart medications unless specifically advised to do so by your doctor.

The Pauling Therapy also advises eliminating trans fats and refined sugar from the diet – while getting sufficient exercise and drinking plenty of pure, filtered water. A heart-healthy organic diet, rich in beneficial omega-3 oils, can also help reduce the risk of arterial plaque.

Hitting big  pharma in the pocketbook: The Pauling Therapy has the potential to bankrupt drug-based medicine

If the conventionally-trained medical community seems to be distinctly unenthused by the Pauling Therapy, it’s not hard to determine why.

Many natural health experts and advocates have observed that this low-cost regimen – for which no prescription is needed – has the potential to bring the medical and pharmaceutical industries to financial ruin.

Sound extreme?

Not when you consider the fact that heart-related surgical procedures can bring in more money to metropolitan hospitals than any other procedure – in many cases accounting for a stunning 30 to 40 percent of a hospital’s total income.

Clearly, the concept of patients becoming responsible for their own health – and employing natural vitamins, minerals and amino acids in order to combat and eliminate heart disease – is terrifying for big pharma!

Renowned scientist Dr. Pauling insisted that the proper use of vitamin C and lysine can prevent, and even cure, heart disease. Although the protocol has never been taken seriously (or properly studied) by conventional medical authorities, many patients have discovered the efficacy of the therapy – and its lifesaving benefits – for themselves.

Sources for this article include:

HeartTechnology.com
PaulingTherapy.com
CDC.com