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Daily dose of baking soda may help combat autoimmune disease

Reproduced from original article:
www.naturalhealth365.com/autoimmune-disease-baking-soda-3415.html

by:  | May 25, 2020

autoimmune-disease(NaturalHealth365) According to the National Institutes of Health, over 23 million Americans currently live with some type of autoimmune disease – which can encompass such potentially debilitating conditions as rheumatic arthritis, lupus, irritable bowel disease, type 1 diabetes, psoriasis, multiple sclerosis and Hashimoto’s thyroiditis. Autoimmune diseases – which arise when the immune system mistakenly attacks the body’s own organs, tissues and cells – are notoriously complex and difficult to treat.

But encouraging research shows that a common, familiar household staple – baking soda – can function as a potent weapon against them.

A recent study not only revealed baking soda’s ability to fight autoimmune disease – but showcased its ability to work at the cellular and molecular level.  For a lowly cooking ingredient, baking soda seems to have some highly sophisticated and powerful effects!

Can baking soda help those suffering with autoimmune disease?

Baking soda, also known as bicarbonate of soda, has a variety of household and medical uses.

It has long been used as a natural toothpaste, a non-toxic deodorant and a cheap, quick-acting antacid to treat heartburn. In addition, some nephrologists advise small daily doses of baking soda to slow the progression of chronic kidney disease.

After clinical studies affirmed baking soda’s beneficial effects on chronic kidney disease, researchers wondered what other conditions it could improve.  And they soon had their answer.

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In a study conducted by scientists at Medical College of Georgia at Augusta University and published in April 2018 in Journal of Immunology, the team found that drinking baking soda in water every day for two weeks helped to reduce the destructive inflammation of autoimmune disorders.

The key to baking soda’s action was the way it affected mesothelial cells on the exterior of the spleen. These specialized immune cells have microvilli that sense the environment and warn when an immune response is needed in order to defend against invading pathogens.

But in autoimmune disorders, this response can be inappropriate, excessive and damaging.

Baking soda helped the cells to convey the message that a protective immune response need not be triggered. In the words of study co-author Dr. Paul O’Connor, the compound helped reassure the immune system that there was no pathogen to be fought. “It’s most likely a hamburger, not a bacterial infection,” explained Dr. O’Connor.

It’s official: Baking soda reduces the inflammatory actions of cells

Bicarbonate of soda also affects the population of immune cells called macrophages, which engulf and destroy pathogens.  The scientists found that it shifted the macrophage population to a higher percentage of anti-inflammatory M2 macrophages, while decreasing pro-inflammatory M1 macrophages.

Although the initial research was conducted on rats, the researchers studied healthy human volunteers as well.  And these human participants also experienced an anti-inflammatory response from the baking soda.

In addition, the group who took baking soda had more inflammation-regulating T cells, which discourage the immune system from attacking tissue.

The researchers concluded that baking soda was a “cheap, relatively safe, effective and … noninvasive method to activate cholinergic anti-inflammatory pathways, which may be of benefit to patients suffering from a multitude of inflammatory disease states.”

In a separate study published in Proceedings of the National Academy of Sciences, researchers found that baking soda could specifically benefit rheumatoid arthritis – an autoimmune condition. The scientists concluded that baking soda and water helped reduce inflammation and disease severity.

Baking soda’s antiviral effects are currently being studied

Scientists have found that certain pH-dependent viruses – which happen to include some influenza viruses and coronaviruses – are most able to replicate and spread under acid conditions (pH6.0) and are deactivated completely at pH 8.0.

Baking soda raises acidic pH to higher alkaline levels – a fact with exciting implications for possibly slowing the spread of COVID-19 and other viral infections. While clinical studies have yet to be performed, cell and animal studies attest to the effects of alkalinity on viruses.

In fact, baking soda has been used to fight a pandemic in the past.  In 1918 and 1919, Dr. Edward R. Hays – a physician with the U.S. Health Department – utilized baking soda against the Spanish flu, claiming that it could lead to a resolution of symptoms within 36 hours.

In addition to antiviral and inflammation-fighting effects, baking soda can improve general health in myriad other ways.  According to noted doctor and author Dr. Eddy Bettermann, baking soda increases bicarbonates in the blood – in turn increasing carbon dioxide and helping with oxygenation of body organs.

And Dr. Lynda Frassetto of the University of California notes that baking soda can reduce acidic wastes in the body – which show up as cholesterol, fatty acids, uric acid, phosphate and kidney stones.

How much baking soda should I take?

While the University of Georgia scientists did not reveal the daily amount of baking soda used in the study, many natural health experts recommend half a teaspoon of baking soda dissolved in a cup or two of water a day.

Of course, check with your doctor before using baking soda to treat kidney disease, autoimmune disorders or any other medical condition. It is especially important to seek your physician’s guidance if you have high blood pressure, as baking soda is very high in sodium.

Health warning: To avoid possible gastric rupture, don’t take baking soda when your stomach is excessively full – such as after a huge meal.

While autoimmune disease can be a formidable foe, the simple, old-fashioned remedy of baking soda in water may emerge as a front-line defense against it.

Sources for this article include:

Jagwire.Augusta.Edu
DrEddyMD.com
Sciencedaily.com

Could you be one of the 7.2 million people that have undiagnosed diabetes?

Reproduced from original article:
https://www.naturalhealth365.com/undiagnosed-diabetes-3457.html
by:  | June 28, 2020

undiagnosed-diabetes(NaturalHealth365) With the release of new statistics from the American Diabetes Association, it’s clear that the incidence of diabetes is nearing epidemic proportions in the United States. Not only do a whopping 34.2 million adults now have diabetes – but over 7 million of them are living with undiagnosed diabetes.

Moreover, a stunning 88 million American adults currently have prediabetes (elevated blood sugar levels that progress to full-blown type 2 diabetes roughly 70 percent of the time). Even more disturbingly, diabetes may be accompanied by an increased risk of death from cardiovascular disease.

In addition, the U.S. Centers for Disease Control and Prevention (CDC) reports that having diabetes and/or heart disease can raise the risk of poor outcomes and mortality from COVID-19 – which continues to claim lives around the globe. When it comes to these serious health problems, ignorance is definitely not bliss – especially in these challenging times.

Warning: The insidious nature of undiagnosed diabetes can lead to irreversible harm

Type 2 diabetes results when the body does not produce or utilize enough insulin to control levels of blood sugar (glucose).  Diagnosis can be made through a simple blood test, with a fasting plasma level of 126 mg/dL considered the medical threshold for diabetes.

Once diabetes is diagnosed, it can often be managed through simple lifestyle changes involving proper diet and exercise.  And, yes, in the short term: your doctor may also recommend medication, such as metformin.

Yet, even with clear-cut and simple methods of diagnosis, almost a quarter of all cases of diabetes are going undiagnosed.  Why?

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Because diabetes is a “sneaky” disease that progresses very slowly. Experts say that it can take up to a decade to develop – and, by the time symptoms finally appear, irreparable damage may have already occurred.

In other words: poor blood sugar control can lead to serious, irreversible complications years down the road.

Adults with diabetes are two to four times more likely to die from heart disease

According to the American Heart Association, complications of diabetes can include coronary artery disease, heart attack, stroke and atherosclerosis. Unsurprisingly, adults with diabetes may experience up to a four-fold increased risk of death from heart disease.

In fact, cardiovascular disease is the leading cause of death and hospitalization in people with type 2 diabetes.  But it is not only the heart that can be affected.  Diabetes takes a grim toll on the entire body.

Other complications of undiagnosed type 2 diabetes include neuropathy (nerve damage), kidney disease, retinopathy, blindness, erectile dysfunction, gastroparesis (the slowed movement of food to the intestines) increased risk of gum disease and heightened susceptibility to bacterial and fungal skin infections.

Poor circulation exacerbated by diabetes can also cause damage to the feet, necessitating amputations.

Do you know the symptoms and risk factors of diabetes?

The first line of defense against diabetes, in addition to timely blood tests, is familiarity with the symptoms.  These can include frequent urination, excessive thirst, unintended weight loss, fatigue, blurred vision, slow wound healing and tingling or burning sensations in the hands and feet.

Dry, itchy skin – and areas of darkened skin in the folds and creases of the body – can also signal the presence of diabetes.

If you are experiencing symptoms of diabetes, ask your doctor for a blood test.  Turning 45 is also an occasion to be tested, with the ADA recommending routine re-testing every three years – even if your blood sugar is normal.

Keep in mind, risk factors for diabetes include having prediabetes, being overweight, being age 45 or older, having a sedentary lifestyle, having hypertension, having a parent or sibling with type 2 diabetes and having high triglycerides or low levels of healthy HDL cholesterol. Individuals of African American, Hispanic, American Indian, Asian American or native Alaskan descent are also at higher risk of developing diabetes.

Additional danger: 3.7 million Americans have an undiagnosed heart condition

Some heart conditions are asymptomatic before becoming apparent. According to the American Heart Association, three of the most common heart conditions are bicuspid aortic valve disease, arrhythmias and cardiomyopathy, or heart muscle dysfunction.

Of course, regular check-ups through your primary care physician can help detect heart problems.

While cholesterol and blood pressure readings are useful starting points to evaluate heart health, your doctor may also recommend an ultrasound, MRI or stress test.  Naturally, if you or your doctor has specific concerns about your heart health, see a cardiologist.

When it comes to heart attacks, research reveals that men and women can experience vastly different symptoms. While severe chest pain is considered the “classic” sign in men and women alike, women may also experience under-recognized symptoms such as nausea, vomiting, lightheadedness, cold sweats, fatigue and pain in the jaw, neck or back.

If you have these symptoms with no identifiable cause, call 911 immediately.

Under-diagnosed conditions may be skewing our perceptions about the lethality of COVID-19

Experts report that over 94 percent of people dying from COVID-19 have underlying conditions such as diabetes, heart disease and obesity. This would imply that the remaining 6 percent of people losing their lives to COVID-19 were free of underlying health problems.

Yet, the perception of healthy people dying from COVID-19 may be misleading.  With so many instances of undiagnosed heart disease and diabetes in the United States, isn’t it quite possible that these people were not as totally “healthy” as they appeared?

In any case, one of the most important and sensible things we can do to battle COVID-19 is to protect ourselves from the comorbidities that the virus can exploit.

As noted endocrinologist and diabetes expert Dr. James Dudl puts it: “All (diabetes) complications are preventable. And, the treatments are safe.”

In other words, even if we take COVID-19 “out of the picture,” identifying and dealing with undiagnosed diabetes is still a definite win/win.  Save yourself from premature death, take better care of your health today.

Sources for this article include:

PinnacleCare.com
HeartInsight.org
PacificMedicalCenters.org
CDC.gov

Coconut Water Reduces Body Weight and Blood Sugar

© 24th June 2020 GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here www.greenmedinfo.com/greenmed/newsletter
Reproduced from original article:
https://greenmedinfo.com/blog/coconut-water-reduces-body-weight-and-blood-sugar

Posted on: Wednesday, June 24th 2020 at 3:45 pm

Written By: GreenMedInfo Research Group
This article is copyrighted by GreenMedInfo LLC, 2020

Fresh coconut water is a staple in many diets around the world, including those of India and other tropical countries. But it goes beyond being a refreshing, thirst-quenching drink. Here’s a rundown of its research-backed benefits, such as decreased blood glucose and body weight for improved health

Coconut water is nature’s gift in one complete package. It’s the liquid found in the center of a young, green coconut, helping nourish the fruit. Its wide range of applications is justified by its unique chemical composition of sugars, vitamins, minerals and amino acids, as well as phytohormones.[i]

The average green coconut offers about one-half to 1 cup of coconut water. One cup contains 46 calories along with 9 grams (g) of carbohydrates, 3 g of fiber, 2 g of protein, 11% of the recommended daily intake (RDI) of sodium and 17% of the RDI of potassium.[ii]

Coconut is known to be an excellent alternative to sports drinks, a natural refreshing beverage that could be used for whole-body rehydration post-exercise.[iii] Nature also filters coconut water through an intensive purification process, eliminating safety issues commonly tied with municipal water systems and even sports beverages comprising synthetic ingredients.

Let’s recap some of the whole-body benefits of consuming fresh coconut water, starting with a 2018 study looking into its effects on body weight and glucose levels.

Slashing Blood Glucose and Excess Pounds Naturally

A group of researchers sought to compare the effects of higher saturated fatty acid and fiber intake, as provided by fresh coconut, and monounsaturated fatty acid (MUFA) and fiber intake via a combination of groundnut oil and groundnuts.[iv] They then measured indicators such as blood insulin and glucose levels, along with blood pressure, in healthy adults.

The researchers divided the 80 healthy subjects they recruited into two randomized groups, consuming a standardized diet along with either 100 g of fresh coconut or an equal amount of groundnuts and groundnut oil for 90 days.

The results showed that fasting blood sugar in both groups was significantly reduced. Yet they also observed a significant reduction in body weight in the coconut group, along with a notable increase in diastolic pressure in the groundnut group.

The researchers noted, “Fresh coconut-added diet helps reduce blood glucose levels and body weight in normal healthy individuals.” This supports previous studies that vouch for the blood-sugar lowering action of the natural drink, offering potential anti-diabetes benefits despite its naturally sweet taste.[v]

Interestingly, while groundnut intake reflected an increase in diastolic pressure, coconut was shown in previous research to push down systolic and diastolic pressures in hypertensive subjects.[vi] Additional animal research shows coconut water prevents and reverses fructose feeding-induced high blood pressure, along with reducing oxidative stress and insulin resistance.[vii]

Coconut water vinegar, too, has been promoted as a food ingredient with potential anti-obesity and anti-inflammatory effects, thanks to alterations in the gut microbiota due to increased populations of Bacteroides and Akkermansia genera bacteria.[viii]

Other Wondrous Health Benefits of Coconut

  • Anti-ulcer properties: Both coconut water and coconut milk demonstrate strong anti-ulcer activity against chemicals such as indomethacin, a non-steroidal anti-inflammatory drug (NSAID).[ix]
  • Lipid-lowering action: Coconut water has a lipid-modulating effect similar to the drug lovastatin in rats fed a fat- and cholesterol-enriched diet.[x]
  • Alzheimer’s disease protection: In a novel study, young coconut juice showed positive future implications in the prevention and treatment of Alzheimer’s disease in menopausal women.[xi]
  • Sperm preservation: A coconut water-based extender, ACP-116c, along with 20% egg yolk and 3% glycerol, was effective for the cryopreservation of semen.[xii]
  • Antibacterial benefits: Three peptides were purified and identified from green coconut water, exhibiting remarkable antimicrobial action against pathogenic bacteria.[xiii]
  • Kidney stone fighter: In a study on rats with kidney stones, coconut water barred crystals from sticking to the kidneys and other parts of the urinary tract. In addition, it slashed the number of crystals formed in the urine.[xiv]

While pure, clear water remains the beverage of choice to stay cool and hydrated, some ice-cold natural coconut water can be a sound option, replacing electrolytes lost from sweating without the added sugar. Its close kin, coconut oil, is equally celebrated for its own set of healing and nourishing benefits.


References

[i] Yong JW et al “The chemical composition and biological properties of coconut (Cocos nucifera L.) water” Molecules. 2009 Dec 9;14(12):5144-64.

[ii] SELF Nutrition Data https://nutritiondata.self.com/facts/nut-and-seed-products/3115/2

[iii] Mohamed S et al “Rehydration after exercise with fresh young coconut water, carbohydrate-electrolyte beverage and plain water” J Physiol Anthropol Appl Human Sci. 2002 Mar;21(2):93-104.

[iv] Venogupal V et al “Diet Enriched With Fresh Coconut Decreases Blood Glucose Levels and Body Weight in Normal Adults” J Complement Integr Med. 2018 Feb 20;15(3).

[v] “Hypoglycemic and antioxidant potential of coconut water in experimental diabetes” Food Funct. 2012 Jul;3(7):753-7

[vi] T Alleyne et al “The control of hypertension by use of coconut water and mauby: two tropical food drinks” West Indian Med J. 2005 Jan;54(1):3-8.

[vii] Therapeutic effects of tender coconut water on oxidative stress in fructose fed insulin resistant hypertensive rats. act Source: Asian Pac J Trop Med. 2012 Apr ;5(4):270-6.

[viii] Nurul Elyani et al “Dietary coconut water vinegar for improvement of obesity-associated inflammation in high-fat-diet-treated mice” Food Nutr Res. 2017 ;61(1):1368322. Epub 2017 Sep 21.

[ix] R O Nneli et al “Antiulcerogenic effects of coconut (Cocos nucifera) extract in rats” Phytother Res. 2008 Jul;22(7):970-2.

[x] V G Sandhya et al “Comparative evaluation of the hypolipidemic effects of coconut water and lovastatin in rats fed fat-cholesterol enriched diet” Food Chem Toxicol. 2008 Dec;46(12):3586-92. Epub 2008 Sep 3.

[xi] Nisaudah R et al “Young coconut juice, a potential therapeutic agent that could significantly reduce some pathologies associated with Alzheimer’s disease: novel findings” Br J Nutr. 2011 Mar ;105(5):738-46. Epub 2010 Nov 30.

[xii] M A Silva et al “Cryopreservation of collared peccaries (Tayassu tajacu) semen using a powdered coconut water (ACP-116c) based extender plus various concentrations of egg yolk and glycerol” Theriogenology. 2012 Apr 24. Epub 2012 Apr 24.

[xiii] Santi M et al “Identification and structural insights of three novel antimicrobial peptides isolated from green coconut water” Peptides. 2009 Apr;30(4):633-7. Epub 2008 Dec 6.

[xiv] Gandhi M et al “Prophylactic effect of coconut water (Cocos nucifera L.) on ethylene glycol induced nephrocalcinosis in male wistar rat” Int Braz J Urol. 2013 Jan-Feb;39(1):108-17.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.

Eight Reasons to Consume Bee Propolis

© 11th June 2020 GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here www.greenmedinfo.com/greenmed/newsletter
Reproduced from original article:
www.greenmedinfo.com/blog/eight-reasons-consume-bee-propolis

Posted on: Saturday, June 6th 2020 at 3:45 pm

Bee propolis, a natural resin sourced from honeybees, hosts numerous health benefits thanks to its antiseptic, antimicrobial, antiviral and anti-inflammatory properties. Here, we’ve outlined eight of the main benefits of consuming bee propolis

Bee propolis, a kind of “bee glue” or resinous substance used by bees to protect against fungus and seal holes or cracks in the hive, is garnering more attention in the health and wellness community thanks to a growing body of research highlighting its therapeutic benefits.[i],[ii]

Composed mainly of resin and wax, bee propolis is full of phenolic compounds, esters and 12 different kinds of flavonoids that contribute to its anti-inflammatory, antibacterial, antifungal and antioxidant properties.[iii] If you’ve never tried bee propolis, here are eight excellent examples of why you should consider adding bee propolis products into your routine and diet:

1. Bee Propolis Protects Against the Common Cold

Research has shown that due to the antimicrobial properties of bee propolis, it may be useful in relieving symptoms and shortening the duration of the common cold.[iv] Additionally, parents may use propolis as a supplement for preventing colds and flu-like illnesses in children, as it has immune-activating properties and has been shown to reduce the likelihood of colds in children.[v],[vi],[vii]

2. Bee Propolis Fights Upper Respiratory Infections in Children and Adults

The antimicrobial effects of propolis have been shown to effectively fight several strains of bacteria in patients with upper respiratory infections.[viii] Researchers believe that bee propolis could be used as a natural antibacterial therapy to prevent upper respiratory infections in both children and adults.[ix]

3. Bee Propolis Has Antifungal Properties

Researchers have studied the antifungal effects of propolis on onychomycosis, a common nail infection caused by fungus that causes nails to weaken and become brittle or ragged.[x],[xi]

Conventional treatment methods for onychomycosis include medications that often cause severe side effects or interact with other medications, causing the patient to stop treatment.[xii] Because researchers have demonstrated the effective topical antifungal properties of bee propolis, many believe that it could be used as a less expensive remedy for onychomycosis without adverse effects.[xiii]

Researchers have also studied the effects of propolis against 40 yeast strains of the Candida fungus, demonstrating that propolis is effective in inhibiting the growth of these common fungi.[xiv] Common candida infections include oral thrush and vaginal yeast infections, both of which have been shown to benefit from propolis-based topical treatments.[xv],[xvi],[xvii]

4. Bee Propolis May Protect Against Cancer

Propolis contains a substance called caffeic acid phenethyl ester (CAPE), which activates DNA damage signaling in cancer cells, making it a potent antitumor therapy in the treatment and prevention of cancer.[xviii],[xix]

In fact, some researchers believe propolis may be as effective as chemotherapy or conventional chemopreventative drugs, without the adverse side effects associated with chemotherapy.[xx]

5. Antidiabetic Properties of Bee Propolis

A heterogeneous disease caused by insulin secretion or action defects, diabetes mellitus is one of the more common chronic diseases affecting Americans today.[xxi] In various studies, bee propolis extract effectively reduced hyperglycemic and oxidative stress associated with hyperglycemia and had ameliorating effects on cardiovascular health in diabetic subjects.[xxii],[xxiii]

Royal jelly, a healing secretion of bees intended for their nourishment, also has potent anti-diabetic qualities and significantly lowers blood sugar levels and oxidative stress caused by hyperglycemia.[xxiv]

6. Bee Propolis Offers Neuroprotective Benefits

Propolis has inhibitory effects against neuronal cell death, possibly preventing the onset of several neurodegenerative and ischemic disorders.[xxv] This may be due to propolis’ effects on oxidative stress, which is believed to be the underlying pathogenesis of several neurodegenerative diseases, including Alzheimer’s and other forms of dementia.[xxvi],[xxvii]

7. Bee Propolis as a Potential Gastrointestinal Treatment

The cytotoxic and cytostatic effects of CAPE, an ester contained in bee propolis, make it an excellent potential therapy in the treatment and prevention of gastric cancers.[xxviii] Additional gastrointestinal benefits of propolis include treatment and prevention of ulcerative colitis, probably due to its antioxidant, antiulcer and anti-inflammatory properties.[xxix]

8. Bee Propolis for Dermatology and Skin Care

Bee propolis has been studied for its topical effects on a variety of skin conditions, including burn treatment, wound healing, insect bites, UV-induced photodamage, oral infections and sores, and the antibacterial and anti-inflammatory nature of bee propolis makes it a popular ingredient in many natural cosmetic products.[xxx],[xxxi],[xxxii],[xxxiii],[xxxiv]

Propolis has also been tested for its effects on acne. Conventional antibiotic treatments for this follicular skin disease have become less effective due to the rise of antibiotic-resistant strains of Propionibacterium acnes, but researchers have demonstrated that natural antimicrobial extracts such as propolis seem to effectively reduce redness and lessen scarring.[xxxv]

Safety Concerns Associated With Bee Propolis

Oral or topical use of bee propolis can cause allergic reactions, especially in individuals allergic to honey bee or other bee stings or to asthmatic individuals, with allergies presenting as contact dermatitis or oral mucositis.[xxxvi],[xxxvii]

Nevertheless, researchers believe that while there is a chance for allergic reaction and the exact dosage of propolis has yet to be determined, there is vast potential for the use of this natural and promising substance for those without allergies.[xxxviii],[xxxix]

For more information and additional research studies, please visit the GreenMedInfo.com research database on bee propolis and other bee products such as honey and bee venom


References

[i] Oxid Med Cell Longev. 2017; 2017: 1259510.

[ii] J Intercult Ethnopharmacol. 2016 Jun-Aug; 5(3): 308-311.

[iii] Oxid Med Cell Longev. 2017; 2017: 1259510.

[iv] Adv Pharmacol Sci. 2013; 2013: 308249.

[v] Rom J Virol. 1995 Jul-Dec;46(3-4):115-33.

[vi] J Intercult Ethnopharmacol. 2016 Jun-Aug; 5(3): 308-311.

[vii] Am J Chin Med. 2005;33(2):231-40.

[viii] Arzneimittelforschung. 1993 Aug;43(8):921-3.

[ix] J Chemother. 2006 Apr;18(2):164-71.

[x] Version 1. F1000Res. 2019; 8: F1000 Faculty Rev-968.

[xi] Front Microbiol. 2018; 9: 779.

[xii] Front Microbiol. 2018; 9: 779.

[xiii] Front Microbiol. 2018; 9: 779.

[xiv] J Med Food. 2011 Jan-Feb;14(1-2):128-34. doi: 10.1089/jmf.2009.0296. Epub 2010 Dec 4.

[xv] Evid Based Complement Alternat Med. 2015; 2015: 287693.

[xvi] Int J Gynaecol Obstet. 2005 May;89(2):127-32.

[xvii] Evid Based Complement Alternat Med. 2013; 2013: 351062.

[xviii] Integr Cancer Ther. 2018 Sep; 17(3): 867-873.

[xix] Folia Histochem Cytobiol. 2012 Apr 24;50(1):25-37. doi: 10.2478/18693.

[xx] Integr Cancer Ther. 2018 Sep;17(3):867-873. doi: 10.1177/1534735417753545. Epub 2018 Feb 2.

[xxi] Evid Based Complement Alternat Med. 2017; 2017: 5439645.

[xxii] Clin Biochem. 2005 Feb;38(2):191-6.

[xxiii] Evid Based Complement Alternat Med. 2017; 2017: 5439645.

[xxiv] Masataka Nomura, Naomi Maruo, Yoshito Zamami, Shingo Takatori, Shima Doi, Hiromu Kawasaki. [Effect of long-term treatment with royal jelly on insulin resistance in Otsuka Long-Evans Tokushima Fatty (OLETF) rats]Yakugaku Zasshi. 2007 Nov ;127(11):1877-82. PMID: 17978564

[xxv] J Agric Food Chem. 2008 Oct 8;56(19):8944-53. doi: 10.1021/jf8014206. Epub 2008 Sep 12.

[xxvi] Oxid Med Cell Longev. 2017; 2017: 7984327.

[xxvii] Oxid Med Cell Longev. 2018; 2018: 7074209.

[xxviii] Evid Based Complement Alternat Med. 2018; 2018: 2035820.

[xxix] Evid Based Complement Alternat Med. 2018; 2018: 2035820.

[xxx] Evid Based Complement Alternat Med. 2016; 2016: 8473937.

[xxxi] Oxid Med Cell Longev. 2017; 2017: 1259510.

[xxxii] Antioxidants (Basel). 2019 May; 8(5): 125.

[xxxiii] Burns Trauma. 2015; 3: 9.

[xxxiv] Molecules. 2020 Jan 28;25(3). pii: E556. doi: 10.3390/molecules25030556.

[xxxv] Clin Pharmacol. 2018; 10: 175-181.

[xxxvi] Drug Saf. 2008;31(5):419-23.

[xxxvii] J Pharm Bioallied Sci. 2011 Oct-Dec; 3(4): 479-495.

[xxxviii] Adv Pharmacol Sci. 2013; 2013: 308249.

[xxxix] Oxid Med Cell Longev. 2017; 2017: 1259510.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.

Why metabolic syndrome is now more deadly than ever

Reproduced from original article:
www.naturalhealth365.com/metabolic-syndrome-deadly-3427.html
by:  |  June 4, 2020
(NaturalHealth365) Metabolic syndrome is a lifestyle-related illness that has a massive negative impact on our healthcare system and individuals. But is rarely talked about.  In fact, this condition contributes greatly to 70% of deaths worldwide,  according to the WHO.

Simply put, metabolic syndrome is the prevalence of a combination of lifestyle-related diseases. You’ll know if it affects you if you have at least three of the following; a large waist size (40″ in men, 35″ in women), higher than 150mg/dL in triglycerides, low HDL cholesterol (lower than 40mg/dL in men, and 50mg/dL in women), blood pressure higher than 130/85 mm Hg, or a fasting blood sugar level of over 100mg/DL.  Of course, taking blood pressure or cholesterol medication are also an indication of metabolic syndrome issues.

Let’s not forget how chronic illnesses such as type 2 diabetes, obesity, and cardiovascular issues complement each other. Once you suffer from one, the others can develop easily.  The truth is that 40% of the U.S. population is suffering from metabolic syndrome.

If you have just one of these risk factors, modifying your lifestyle must become a priority.  And, in the midst of the COVID-19 crisis, quantitative research in China and the USA reveal staggering evidence as to why metabolic syndrome is now more dangerous than ever.

Statistics reveal these COVID-19 susceptibility risk factors

In early-stage research out of Wuhan, China, almost 50% of cases had an underlying condition related to the syndrome. 20% of cases had type 2 diabetes, 15% with hypertension and 15% of cases had cardiovascular issues. As the epicenter moved toward the USA, the same trends continued.

From February 12 to March 28, statistical research revealed that one in three hospitalized cases had at least one risk factor of metabolic syndrome. A staggering 11% of cases had type 2 diabetes. From the March 1 to April 6, 40% of hospital admissions had either diabetes or uncontrolled blood sugar upon admission.  In addition, 85% of people who suffer from type 2 diabetes are also overweight or obese.

Do NOT ignore the health dangers linked to toxic indoor air.  These chemicals – the ‘off-gassing’ of paints, mattresses, carpets and other home/office building materials – increase your risk of headaches, dementia, heart disease and cancer.

Get the BEST indoor air purification system – at the LOWEST price, exclusively for NaturalHealth365 readers.  I, personally use this system in my home AND office.  Click HERE to order now – before the sale ends.

The strong link between hospitalized COVID-19 cases and metabolic syndrome is undeniable!

Research shows that in hospitalized cases, body mass index (BMI) is one of the key predictors of COVID-19 cases.  In fact, a BMI more than 40kg/m2 is the highest predictor of hospitalized COVID-19 risk factors only behind age.  Unfortunately, most people remain uninformed about this crucial information.

Metabolic syndrome drastically decreases your chances of survival

The research is very clear: your risk of premature death is much greater with the underlying health conditions associated with metabolic syndrome.  In the February and March study, 78% of ICU admissions had one of the risk factors, and a staggering 94% of deaths had at least one of these underlying health conditions.

In the March and April study, death rates were four times more likely in those with diabetes.  Almost 29% of hospitalized cases of those with diabetes resulted in death, compared to only a 6% fatality rate in those without diabetes.

Obese people are more susceptible to respiratory based illnesses such as pneumonia.  So this research from academic hospitals doesn’t come as a surprise.

In most cases, type 2 diabetes, cardiovascular problems, and obesity are lifestyle-related illnesses. To reduce your chances of metabolic syndrome and the possibility of a severe COVID-19 illness, you must take urgent action for your health today.

Reduce your chances of severe illness by taking these actions today

Thankfully, reducing your chances or treating metabolic syndrome is entirely in your hands. To minimize the risk of cardiovascular disease, related symptoms, or type 2 diabetes; it’s recommended that you build a lifestyle of these healthy habits.

Increase daily movement: The U.S. Centers for Disease Control and Prevention (CDC) recommends that you get 30 minutes of moderate-intensity exercise each day, or 150 minutes per week.

Reduce toxin intake: Sugar, alcohol, and processed foods must be eliminated or limited.  Food in its natural state are best.  Eat more organic vegetables, fruits and local (chemical free) animal products.

Support your natural detoxification system: Unlike the cardiovascular system, the lymphatic system does not have a beating heart to facilitate the transport of toxins out of your body. You need to move each day and drink at least eight glasses of water to help remove the unwanted debris.

While it’s clear that metabolic syndrome, obesity, and diabetes determine fatality and ICU admission probabilities, you can help arm yourself against COVID-19 severity. Regular movement and balanced food and hydration choices will help you become way less susceptible, and not just survive but thrive!

Sources for this article include:

WebMD.com
Thelancet.com
Worldobesity.org
Jamanetwork.com

The Real Pandemic Is Insulin Resistance


Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2020/05/04/insulin-resistance-the-real-pandemic.aspx

Analysis by Dr. Joseph Mercola    Fact Checked
May 04, 2020

STORY AT-A-GLANCE

  • After old age, obesity appears to be the most prominent risk factor for being hospitalized with COVID-19, doubling the risk of hospitalization in patients under the age of 60
  • Most COVID-19 patients have more than one underlying health issue. A study looking at 5,700 New York City patients found 88% had more than one comorbidity. Only 6.3% had just one underlying health condition and 6.1% had none
  • Obesity also makes you more vulnerable to infectious diseases by lowering your immune function
  • Elevated blood glucose levels appear to play a significant role in viral replication and the development of cytokine storms. The real pandemic here appears to be dysregulated glucose metabolism; in other words, insulin resistance
  • Amassing data suggest that even when in close, crowded quarters, the infection rate is rather low, and fit, healthy individuals are more likely to be asymptomatic than not when testing positive for SARS-CoV-2 infection

According to a January 2019 update by the U.S. Centers for Disease Control and Prevention, more than 122 million American adults have diabetes or prediabetes1 — conditions which have been shown to increase your chances of contracting and even dying from COVID-19.2,3,4,5,6,7 As noted in an April 16, 2020, report by The New York Times:8

“Obesity may be one of the most important predictors of severe coronavirus illness, new studies say. It’s an alarming finding for the United States, which has one of the highest obesity rates in the world.”

Obesity Appears To Be Independent Risk Factor for COVID-19

After old age, obesity appears to be the most prominent risk factor for being hospitalized with COVID-19 — doubling the risk of hospitalization in patients under the age of 60 in one study9 — even if the individual has no other obesity-related health problems. A French study10,11 also found obese patients treated for COVID-19 were more likely to require mechanical ventilation.

Dr. Leora Horwitz, director of the Center for Healthcare Innovation and Delivery Science at NYU Langone who co-wrote the paper12 “Factors Associated with Hospitalization and Critical Illness Among 4,103 Patients With Covid-19 Disease In New York City” — which has not yet been peer-reviewed — told The New York Times:13

“Obesity is more important for hospitalization than whether you have high blood pressure or diabetes, though these often go together, and it’s more important than coronary disease or cancer or kidney disease, or even pulmonary disease.”

Most COVID-19 Patients Have More Than One Comorbidity

While obesity may top the list of comorbidities — underlying conditions that make COVID-19 worse — investigations reveal most COVID-19 patients have more than one underlying health issue. A study14 looking at 5,700 New York City patients found 88% had more than one comorbidity. Only 6.3% had just one underlying health condition and 6.1% had none.

In this particular study,15 published in JAMA, high blood pressure at 53.1% beat obesity (41.7%) as the No. 1 most common comorbidity among hospitalized patients, followed by diabetes at 31.7% and coronary artery disease at 10.4%.

Co-author Karina Davidson, senior vice president for the Feinstein Institutes for Medical Research told Time magazine:16

“Having serious comorbidities increases your risk … We want patients with serious chronic disease to take a special precaution and to seek medical attention early, should they start showing signs and symptoms of being infected …”

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Obesity Lowers Immune Function

According to The New York Times,17 one hypothesis for why obesity is worsening COVID-19 has to do with the fact that obesity causes chronic inflammation. Having more pro-inflammatory cytokines in circulation increases your risk of experiencing a cytokine storm. Obesity also makes you more vulnerable to infectious diseases by lowering your immune function.18,19,20,21,22,23

As noted in one such study,24 “there is a positive feedback loop between local inflammation in adipose tissue and altered immune response in obesity.” Yet another scientific review25 pointed out “There is strong evidence indicating that excess adiposity negatively impacts immune function and host defense in obese individuals.” A 2018 review article further explained:26

“Adipose tissue is now considered an extremely active endocrine organ that secretes cytokine-like hormones, called adipokines, either pro- or anti-inflammatory factors bridging metabolism to the immune system.

Leptin is historically one of most relevant adipokines, with important physiological roles in the central control of energy metabolism and in the regulation of metabolism-immune system interplay, being a cornerstone of the emerging field of immunometabolism.

Indeed, leptin receptor is expressed throughout the immune system and leptin has been shown to regulate both innate and adaptive immune responses.”

Glucose Metabolism Influences Cytokine Storms

An April 15, 2020, article27 in The Scientist also reviews new evidence28,29 that sheds further light on why obesity and diabetes are such potent risk factors for severe COVID-19 infection.

In a nutshell, higher blood glucose levels appear to play a significant role in viral replication and the development of cytokine storms. While the research in question looked at influenza A-induced cytokine storms, these findings may well be applicable in COVID-19 as well.

Cytokines are released by your immune system in response to foreign invaders. They, in turn, act as messengers that instruct other immune cells to fight the pathogen. In some cases, this immune response goes into overdrive, resulting in what’s known as a “cytokine storm” that can cause severe tissue damage and lead to death.

cytokine storm response is typically the reason why people die from infections, be it the seasonal flu, Ebola, urinary tract infection or COVID-19. A critical player in cytokine production is the transcription factor interferon regulatory factor 5 (IRF5). In mice, genetically eliminating IRF5 protects them from influenza-induced cytokine storms.30

Interestingly, “the inflammatory response to influenza infections is also known to drive up glucose metabolism,” The Scientist reports,31 “in part so that immune cells have the necessary energy to mount a strong response, and also because the virus needs the sugar to replicate.”

According to researchers at the State Key Laboratory of Virology at Wuhan University, the hexosamine biosynthesis pathway — a glucose metabolism pathway — is responsible for activating IRF5-induced cytokine production in cells and mice. The same pathway is also responsible for viral replication, they say.32,33,34 As reported by The Scientist:35

“Hexosamine biosynthesis starts with glucose and results in an end product called uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) … Liu’s team now shows that O-GlcNAcylation of IRF5 is necessary for the transcription factor’s cytokine-producing activity …

The team also showed that patients infected with influenza have higher blood glucose levels and more O-GlcNacylation of IRF5 than healthy controls. Furthermore, blood glucose levels correlated tightly with levels of inflammatory cytokines.

The results show that ‘there is a connection [between] influenza virus infection, enhanced glucose metabolism and cytokine storm, all linked through O-GlcNAcylation of IFR-5,’ Mengji Lu, a virologist at the University Hospital Essen and a coauthor of the study, writes in an email to The Scientist …”

In a Science Advances press release, co-author Shi Liu states:36

“We believe that glucose metabolism contributes to various COVID-19 outcomes since both influenza and COVID-19 can induce a cytokine storm, and since COVID-19 patients with diabetes have shown higher mortality.”

influenza virus

Insulin Resistance Is the Real Pandemic

So, to summarize, the real pandemic here appears to be dysregulated glucose metabolism; in other words, insulin resistance, which is exceedingly prevalent in the U.S.37,38 Insulin resistance, in turn, is a diet-induced condition.

Specifically, processed foods — which are loaded with added sugars, processed grains and industrially processed omega-6 vegetable oils — are the primary culprits causing insulin resistance, Type 2 diabetes and obesity, and according to FoodNavigator.com,39 doctors are finally starting to talk about the food industry’s role in the COVID-19 pandemic.

“A cardiologist has blamed the food industry for ‘normalizing’ ultra-processed junk food as more evidence emerges suggesting poor diet is the root cause behind increased mortality from COVID-19,” FoodNavigator states, adding:40

“In light of the mounting evidence that obesity and poor diet increases the risk of a severe response to COVID-19 infection, medical professionals now want the public health message urgently updated. And this, they warn, means the food industry bracing itself for regulation, such as bans on advertising and taxes …

Dr. Aseem Malhotra, a London-based cardiologist, told the BBC that a Government and Public Health England failure to tell the public to change its diet would represent an act of ‘negligence and ignorance’ … For him, the pandemic highlighted that it was in the interest of everybody, including those in the food industry, to make sure the population was as healthy as possible.”

Malhotra stresses these views in his April 16, 2020, article41 “COVID-19 and the Elephant in the Room,” published in European Scientist. “Obesity and chronic metabolic disease is killing COVID-19 patients: Now is the time to eat real food,” he says. Indeed, if our public health agencies really want to save lives, it’s time to get onboard with nutrition.

“If this is not the time for Britain to reverse its epidemic of Type 2 diabetes, which as a single condition has been the most costly to the NHS [National Health Service], then when is?” Malhotra writes.42

“Healthcare systems were already overstretched before COVID-19 because of decades of maldistribution of resources due to ‘too much medicine’ combined [with] our collective failure to implement policy changes to address the root cause of diet related disease — the unavoidable junk food environment.

The government public health message enhanced by the media to stay at home, protect the NHS and save lives has been powerful and effective. Given the speed at which health markers for metabolic disease improve from dietary interventions, an equally strong if not more significant population health message should now be to ‘eat real food, protect the NHS and save lives.’

Such implementation backed by policy changes may not just save hundreds and potentially thousands of lives around the world in the coming months but given the high likelihood of another international viral pandemic in the next decade a healthier population and a subsequently more manageable health service will be much better equipped to handle what would then be a smaller mortality peak on the next occasion.”

Junk Food Industry Faces Increasing Pressure

This is timely, considering a Corporate Accountability report,43 announced44 April 21, 2020, highlights the “outsized role” of International Life Sciences Institute (ILSI), a junk food industry front group funded by Coca-Cola, plays in shaping nutritional policies around the globe. According to the Corporate Accountability press release:45

“Notable among the findings is that more than half of the 2020 Dietary Guidelines Advisory Committee — the body that informs both national nutrition policy and how Americans eat and drink — has ties to ILSI …

The food and beverage industry’s role in stymying public health policy and propagating junk science is also taking on new dimensions during today’s pandemic. The surge of diet-related disease behind one in five deaths annually, is putting hundreds of millions of people at high risk of severe illness from COVID19.

‘For decades, Coke, its competitors, and its surrogates like ILSI have trafficked in junk science, co-opted public officials, and bullied advocates like myself …’ said Dr. Esperanza Ceron … ‘But we won’t be silenced. Too much is at stake’ …

‘It’s time for Coke to put something more on ice than its soft drinks,’ said Corporate Accountability Research Director Ashka Naik, a co-author of the report.

‘Coke is telling investors it cares about public health on the one hand, but funds ILSI to block public health safeguards on the other. Its misleading of investors and consumers is a liability that will only grow.’

A resolution … calls on Coke to come clean with its shareholders about its public health harms and liabilities. It would require a public, independent audit of how the corporation is contributing to the crisis of diet-related disease, whether through its products, its marketing, its political interference, or junk science.”

Data Show COVID-19 Isn’t a Significant Threat

In the featured Fundamental Health podcast above, Dr. Paul Saladino interviews Dr. Kirk Parsley about the lifestyle factors that are contributing to the high COVID-19 caseload in the U.S.

Saladino cites findings46 showing that of the roughly 4,800 crew on the U.S. aircraft carrier USS Theodore Roosevelt, 660 had tested positive for SARS-CoV-2. (As of April 23, when all of the crew had reportedly been tested, 840 tested positive.47) However, as noted by Saladino and reported by Business Insider,48 60% were asymptomatic, meaning they had no symptoms. Only one crewmember has died,49 and as of April 23, none were in intensive care.50

Similarly, among the 3,711 passengers and crew onboard the Diamond Princess cruise ship, 712 (19.2%) tested positive for SARS-CoV-2, and of these 46.5% were asymptomatic at the time of testing. Of those showing symptom, only 9.7% required intensive care and 1.3% died.51

Military personnel, as you would expect, tend to be healthier than the general population. Still, the data from these two incidents reveal several important points to consider. First of all, it suggests that even when living in close, crowded quarters, the infection rate is rather low.

Only 17.5% of the USS Theodore Roosevelt crew got infected — slightly lower than the 19.2% of those onboard the Diamond Princess, which had a greater ratio of older people.

Second, fit and healthy individuals are more likely to be asymptomatic than not — 60% of naval personnel compared to 46.5% of civilians onboard the Diamond Princess had no symptoms despite testing positive.

Saladino and Parsley go on to discuss current pandemic response efforts, such as the recommendation (and in some areas mandate) to wear a face mask when venturing outside. Both are convinced wearing a bandana across your face is completely useless, for the simple fact that the virus is so small it can easily slip through the fabric.

Parsley also reviews the statistics as of April 21, 2020, using Worldometer data,52 showing only 1.7% of American COVID-19 cases require hospitalization, and of those an even smaller ratio will actually die. Is it really reasonable to shut down the entire country and place everyone under house arrest over a 1.7% hospitalization rate?

So-called “COVID-19 cases,” by the way, simply means people who have tested positive using an RT-PCR (reverse transcription polymerase chain reaction) test, which is used to diagnose an active infection by detecting the presence of SARS-CoV-2 genetic material.53

Mortality Rates Are Still Vastly Overestimated

The hospitalization is actually bound to be even lower than 1.7% in real life, seeing how few people have actually been tested. Preliminary findings54 published April 17, 2020, reveal the actual infection rate in Santa Clara County, California, is likely to be between 50- and 85fold higher than the number of confirmed cases.

This is based on seroprevalence data, meaning antibody testing. If you have antibodies against a particular pathogen, you’ve been exposed to it in the past, whether you developed symptoms or not, and you’re now immune to it.

Between April 3 and April 4, 3,330 Santa Clara county residents were tested for antibodies to SARS-CoV-2 using a lateral flow immunoassay. In an effort to ensure results were as accurate as possible, they were adjusted for test performance characteristics using three estimates:

  1. Test manufacturer data
  2. A sample of 37 positive and 30 negative controls tested at Stanford
  3. A combination of both

According to the authors:55

“The unadjusted prevalence of antibodies to SARS-CoV-2 in Santa Clara County was 1.5% … and the population-weighted prevalence was 2.81% … Under the three scenarios for test performance characteristics, the population prevalence of COVID-19 in Santa Clara ranged from 2.49% … to 4.16% …

These prevalence estimates represent a range between 48,000 and 81,000 people infected in Santa Clara County by early April, 50-85-fold more than the number of confirmed cases.

Conclusions: The population prevalence of SARS-CoV-2 antibodies in Santa Clara County implies that the infection is much more widespread than indicated by the number of confirmed cases. Population prevalence estimates can now be used to calibrate epidemic and mortality projections.”

Randomized antibody tests done in New York show that upward of 20% of the population in New York have been infected, suggesting that the virus had spread far more widely than known.56

This is also strong support for a lower fatality rate as previous inaccurate PCR tests were only done on sick people and there was no idea how many in the population had been infected. Since more people are infected, this increases the denominator in the calculation and lowers the mortality rate calculation.

Blood Pressure Drugs May Worsen COVID-19

Making matters worse, the drugs routinely used to treat lifestyle-induced afflictions such as high blood pressure, diabetes and heart disease may also be contributing to adverse outcomes in patients with COVID-19. According to Reuters:57

“A disproportionate number of patients hospitalized by COVID-19 … have high blood pressure. Theories about why the condition makes them more vulnerable … have sparked a fierce debate among scientists over the impact of widely prescribed blood-pressure drugs.

Researchers agree that the life-saving drugs affect the same pathways that the novel coronavirus takes to enter the lungs and heart. They differ on whether those drugs open the door to the virus or protect against it …

The drugs are known as ACE inhibitors and ARBs … In a recent interview with a medical journal, Anthony Fauci — the U.S. government’s top infectious disease expert — cited a report showing similarly high rates of hypertension among COVID-19 patients who died in Italy and suggested the medicines, rather than the underlying condition, may act as an accelerant for the virus …

There is evidence that the drugs may increase the presence of an enzyme — ACE2 — that produces hormones that lower blood pressure by widening blood vessels. That’s normally a good thing.

But the coronavirus also targets ACE2 and has developed spikes that can latch on to the enzyme and penetrate cells … So more enzymes provide more targets for the virus, potentially increasing the chance of infection or making it more severe.

Other evidence, however, suggests the infection’s interference with ACE2 may lead to higher levels of a hormone that causes inflammation, which can result in acute respiratory distress syndrome, a dangerous build-up of fluid in the lungs. In that case, ARBs may be beneficial because they block some of the hormone’s damaging effects.”

This presents significant challenges for patients and doctors alike, as there’s currently no significant consensus on whether patients should discontinue the drugs. The Centre for Evidence-Based Medicine at the University of Oxford in England recommends switching to alternative blood pressure medicines in patients who have only mildly elevated blood pressure and are at high risk for COVID-19.

A paper in NEJM stressed the potential benefits of the drugs instead, saying patients should continue taking them. However, several of the scientists who wrote that paper have done “extensive, industry-supported research on antihypertensive drugs,” Reuters notes.

Dr. Kevin Kavanagh, founder of the patient advocacy group Health Watch USA, believes it would be unwise to allow scientists funded by the drug industry to give clinical directions at this time. “Let others without a conflict of interest try to make a call,” he said.58

Restore Insulin Sensitivity for Long-Term Risk Mitigation

If we want people to survive the next pandemic, whatever that might be, then improving public health has got to be the No. 1 priority going forward. Waiting for a drug cure or vaccine is a fool’s game.

Health care really needs to start emphasizing strategies known to improve overall health rather than throwing drugs at symptoms that don’t address the underlying causes. Robust immune function is necessary to effectively combat COVID-19, and the same is true for all other infectious disease.

When it comes to improving health, addressing insulin resistance is truly key, seeing how it’s a factor in virtually all chronic diseases. And, to do that, we need to dramatically cut down on processed foods.

As noted by Dr. Sandra Weber, president of the American Association of Clinical Endocrinologists, in The New York Times,59 “We know that if you do not have good glucose control, you’re at high risk for infection, including viruses and presumably this one [COVID-19] as well … [improving glucose control] would put you in a situation where you would have better immune function.”

For details on what and when to eat to reverse insulin resistance, see “Want to Defeat Coronavirus? Address Diabetes and Hypertension.” In that article, I also summarize several key strategies for getting and staying healthy and metabolically fit. For additional COVID-19 remedies and top tips, see my COVID-19 Resource Guide.

For those who desire more in-depth understanding of how you can become metabolically flexible and eliminate insulin resistance, consider picking up a copy of my book, “Fat for Fuel.” It goes into far greater detail, providing a comprehensive program that will help optimize your metabolic flexibility and strengthen your immune system — both of which are crucial components of health and disease prevention.

– Sources and References

Diabetes Can Increase Complications of COVID-19


Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2020/04/30/blood-sugar-rising.aspx

Analysis by Dr. Joseph Mercola Fact Checked
April 30, 2020

STORY AT-A-GLANCE

  • For a limited time only, PBS is streaming a free documentary on America’s diabetes epidemic
  • More than 114 million American adults have diabetes or prediabetes and the economic ramifications of this condition are enormous. The U.S. spent $350 billion treating diabetes in 2019 alone
  • One of the best strategies to beat COVID-19 is to get any underlying chronic conditions under control; Type 2 diabetes and high blood pressure can often be reversed via healthy diet and lifestyle
  • Type 2 diabetes is a diet-derived condition. It’s rooted in insulin resistance and faulty leptin signaling, caused by chronically elevated insulin and leptin levels. As such, it can be effectively treated and reversed through dietary and other lifestyle means
  • Research has shown fasting and a cyclical ketogenic diet can improve insulin sensitivity and reverse diabetes. Staying physically active is also important, as excessive sitting blocks a number of insulin-mediated systems, including muscular and cellular systems that process blood sugar

For a limited time only, PBS is streaming a free documentary on America’s diabetes epidemic (it may not be available in all areas; check your local PBS to see if it’s in your area). Coincidentally, diabetes is a comorbidity that can increase your chances of contracting and even dying from COVID-19,1 making this documentary particularly timely.

One of the best strategies to beat COVID-19 is to get any underlying chronic conditions under control. Type 2 diabetes and high blood pressure — both of which have been implicated as underlying factors causing serious COVID-19 disease — can often be reversed via healthy diet and lifestyle.

According to a January 2019 update by the U.S. Centers for Disease Control and Prevention, more than 122 million American adults have diabetes or prediabetes,2 and the economic ramifications of this condition are enormous. The U.S. spent $350 billion treating diabetes in 2019 alone, according to the film.

Also according to the film, projections predict half the American population will be prediabetic or diabetic by 2025. Such predictions reflect poor research because if you use insulin resistance as your definition, 80% of the country is diabetic or prediabetic already.3,4

Glucose Metabolism Influences Cytokine Storms

An April 15, 2020, article5 in The Scientist reviews evidence6,7 that helps explain why obesity and diabetes are such potent risk factors for severe COVID-19 infection.

In a nutshell, higher blood glucose levels appear to play a significant role in viral replication and the development of cytokine storms. While the research in question looked at influenza A-induced cytokine storms, these findings may well be applicable in COVID-19 as well.

Cytokines are signaling molecules that are released by your immune system in response to foreign invaders. They, in turn, act as messengers that instruct other immune cells to fight the pathogen. In some cases, this immune response goes into overdrive, resulting in what’s known as a “cytokine storm” that can cause severe tissue damage and lead to death.

cytokine storm response is typically the primary reason why people die from infections, be it the seasonal flu, Ebola, urinary tract infection or COVID-19. A critical player in cytokine production is the transcription factor interferon regulatory factor 5 (IRF5). In mice, genetically eliminating IRF5 protects them from influenza-induced cytokine storms.8

Interestingly, “the inflammatory response to influenza infections is also known to drive up glucose metabolism,” The Scientist reports,9 “in part so that immune cells have the necessary energy to mount a strong response, and also because the virus needs the sugar to replicate.”

According to researchers at the State Key Laboratory of Virology at Wuhan University, the hexosamine biosynthesis pathway — a glucose metabolism pathway — is responsible for activating IRF5-induced cytokine production in cells and mice. The same pathway is also responsible for viral replication, they say.10,11,12 As reported by The Scientist:13

“Hexosamine biosynthesis starts with glucose and results in an end product called uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) … Liu’s team now shows that O-GlcNAcylation of IRF5 is necessary for the transcription factor’s cytokine-producing activity …

The team also showed that patients infected with influenza have higher blood glucose levels and more O-GlcNacylation of IRF5 than healthy controls. Furthermore, blood glucose levels correlated tightly with levels of inflammatory cytokines.

The results show that ‘there is a connection [between] influenza virus infection, enhanced glucose metabolism and cytokine storm, all linked through O-GlcNAcylation of IFR-5,’ Mengji Lu, a virologist at the University Hospital Essen and a coauthor of the study, writes in an email to The Scientist …”

In a Science Advances press release, co-author Shi Liu states:14

“We believe that glucose metabolism contributes to various COVID-19 outcomes since both influenza and COVID-19 can induce a cytokine storm, and since COVID-19 patients with diabetes have shown higher mortality.”

influenza virus
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Insulin Resistance Is the Real Pandemic

So, the real pandemic here appears to be dysregulated glucose metabolism; in other words, insulin resistance, which is exceedingly prevalent in the U.S.15,16 Insulin resistance, in turn, is a diet-induced condition. Unless addressed, insulin resistance eventually develops into full-blown Type 2 diabetes. As mentioned earlier, if you use sensitive measure for insulin resistance, approximately 80% of the population has this metabolic dysfunction.17,18

Processed foods — which are loaded with added sugars, processed grains and industrially processed omega-6 vegetable oils — are the primary culprits causing insulin resistance, Type 2 diabetes and obesity and, according to FoodNavigator.com,19 doctors are finally starting to talk about the food industry’s role in the COVID-19 pandemic:

“A cardiologist has blamed the food industry for ‘normalizing’ ultra-processed junk food as more evidence emerges suggesting poor diet is the root cause behind increased mortality from COVID-19,” FoodNavigator states, adding:20

“In light of the mounting evidence that obesity and poor diet increases the risk of a severe response to COVID-19 infection, medical professionals now want the public health message urgently updated. And this, they warn, means the food industry bracing itself for regulation, such as bans on advertising and taxes …

Dr. Aseem Malhotra, a London-based cardiologist, told the BBC that a Government and Public Health England failure to tell the public to change its diet would represent an act of ‘negligence and ignorance’ … For him, the pandemic highlighted that it was in the interest of everybody, including those in the food industry, to make sure the population was as healthy as possible.”

Diabetes Is Reversible

As noted by PBS, Type 2 diabetes can be very difficult to control when relying on drugs alone and not doing anything about the underlying lifestyle factors actually causing the problem. While not addressed in the film, the use of insulin in Type 2 diabetes is particularly problematic. If the underlying lifestyle factors are properly addressed, Type 2 diabetes is entirely reversible in most people, and rather easily so.

The reason for this is because Type 2 diabetes is a diet-derived condition. It’s rooted in insulin resistance and faulty leptin signaling, caused by chronically elevated insulin and leptin levels. As such, it can be effectively treated and reversed through dietary and other lifestyle means.

For example, as detailed in my 2019 article “Fasting Prevents and Halts Diabetes,” research has shown fasting can improve insulin sensitivity,21 reverse diabetes22 and support your weight management efforts when combined with exercise.23 While “Blood Sugar Rising” discusses the foundational role of diet in this disease, it does not touch on fasting at all.

This is unfortunate, considering how effective it can be. In a case series paper24,25 published in BMJ Case Reports, Dr. Jason Fung and associates details how fasting can actually be used as a therapeutic alternative for Type 2 diabetes. As noted by the authors, their paper:

“… demonstrates the effectiveness of therapeutic fasting to reverse insulin resistance, resulting in cessation of insulin therapy while maintaining control of blood sugars. In addition, these patients were able to lose significant amounts of body weight, reduce their waist circumference and also reduce their glycated hemoglobin levels.”

Now, a case series paper is not a controlled study; rather, it simply presents the case history of one or more patients and may propose a hypothesis for why a treatment did or did not work. In this case, three diabetic patients between the ages of 40 and 67 participated in a supervised fasting regimen to evaluate the effects on their insulin requirements.

The patients had been diagnosed with Type 2 diabetes for 10, 20 and 25 years respectively, and were taking insulin daily. Of the three patients, two did alternating-day, 24-hour fasts, while one fasted for 24 hours three times a week over a period of several months. The complete manual of the fasting regimen used is described in Fung’s book, “The Complete Guide to Fasting.”26

Two of the patients were able to discontinue all of their diabetes medications while the third was able to discontinue three of his four drugs. All three also lost between 10% and 18% of their body weight.

With another similar trial, The Guardian reported on,27 Type 2 diabetics were placed on a severely restricted calorie diet where they ate just 600 calories a day for eight weeks. By the end of their fast, all were disease-free, and three months later, having returned to their regular diet, seven of the 11 participants remained free of diabetes.

There’s Hope Even for Severe Diabetes

Several studies have even found that repeated episodes of fasting can induce cell growth of pancreatic beta cells in mice.28 The growth is associated with an increased expression of Ngn3,29 a protein involved in converting DNA into RNA critical for endocrine cells in the pancreatic islets of langerhans, the cells responsible for producing insulin.

The increase in islet beta cells induced through intermittent fasting was accompanied by a marked improvement in blood sugar control in the animals. While individuals suffering from Type 1 diabetes often experience near complete inflammatory destruction of the islet beta cells, the same occurs in the later stages of severe Type 2 diabetes as well.

In a BMJ editorial,30 research scientist James DiNicolantonio, PharmD.,31 discusses these results, noting the findings may open the path to reversing Type 2 diabetes in those with “enough discipline and commitment to adopt a lifestyle that would have prevented diabetes in the first place.”32

As a first step, he recommends you first practice a diabetes preventive lifestyle — eating a diet primarily of whole foods, complemented with regular exercise. This will help improve your insulin sensitivity and may prove sufficient for those with a recent diagnosis of diabetes to reverse their condition over time.

In those who fail to respond, he recommends a time-restricted eating protocol, which provides many of the same benefits as longer fasting while being much easier to comply with. Supplemental measures may also be implemented to shield the beta cells from toxicity so they retain functional capacity. For example, reducing islet oxidative stress may be accomplished using spirulina, NAC and/or berberine.33

Ultimately, the goal is to achieve normal blood sugar control without drugs and maintain compliance with a diabetic preventive diet and lifestyle. This also includes physical activity.

Chronic inactivity such as extended sitting is one of the primary risk factors for insulin resistance and Type 2 diabetes. The reason for this is because sitting shuts down or blocks a number of insulin-mediated systems, including muscular and cellular systems that process blood sugar, triglycerides and cholesterol. Standing up activates all of these systems at the molecular level. Dr. James Levine detailed the science of this in our 2014 interview.

Diabetes Takes a Heavy Toll on Health

As detailed in the film, chronically high blood sugar from poor nutrition and lack of exercise can trigger long-term damage to your body and make you more prone to other chronic health problems and diseases, including but not limited to:34,35,36

Neuropathy (nerve damage) and amputation Glaucoma, cataracts and blindness
Infections Kidney disease and kidney failure
High blood pressure, heart disease, heart attacks and stroke Dementia and Alzheimer’s disease

Sugar-Rich Diets Are a Primary Culprit

While PBS largely focuses on the conventional treatment of diabetes, which typically involves insulin and other drugs, it thankfully highlights the fact that sugar- and carb-rich diets are a primary driver.37 Research38 shows that once you reach 18% of your daily calories from sugar, there’s a twofold increase in metabolic harm that promote prediabetes and diabetes.

As a standard recommendation, I strongly advise keeping your total sugar consumption below 25 grams per day, which is about 6 teaspoons. If you have signs of insulin resistance such as hypertension, obesity or heart disease, you’d be wise to limit sugar to 15 grams or less until your weight and other health conditions have normalized.

Sadly, as noted by PBS, “the game is rigged.” Food products are allowed to state “sugar free” on the package, even though they’re loaded with carbohydrates and sugar alternatives. As noted in the film, it’s not just sugar itself that must be avoided, but anything that turns into sugar in your body as well, most notably grains.

In short, a high-grain, low-fat diet is a perfect prescription for diabetes, yet these kinds of foods are allowed to make a number of health claims. This kind of misleading labeling is causing many to think they’re making wise food choices when in fact they’re not.

It would help to remember that just about all processed foods are best avoided. Rather than trying to decipher labels, ditch the processed foods and fast food restaurants and cook from scratch using whole, unprocessed foods. This is by far the easiest and most effective way to improve your diet.

Soybean Oil Promotes Diabetes

One dietary factor not directly addressed in the film is processed vegetable oils. These may actually be worse than fructose in terms of the metabolic harm they cause.39 Soybean oil in particular has a questionable safety profile, and processed foods are positively loaded with it.

Whether partially hydrogenated, organic or genetically modified to be low in linoleic acid, soybean oil can cause dysfunction at a cellular level. Unfortunately, many health authorities have insisted omega-6-rich vegetable oils like soybean oil are healthier than saturated animal fats such as butter, lard and coconut oil, and this myth has been a tough one to dismantle, despite the evidence against it.

Most recently, research40,41,42 published in the January 2020 issue of Endocrinology found soybean oil — the most widely consumed cooking oil in America — can cause metabolic changes associated with:

Autism Alzheimer’s disease
Anxiety Depression
Obesity Insulin resistance
Type 2 diabetes Fatty liver disease

According to the authors, both conventional and genetically engineered soybean oil caused dysfunction in about 100 different genes in the hypothalamus, including genes associated with “inflammation, neuroendocrine, neurochemical and insulin signaling.”

Similar results were reported in a 2015 study,43 in which soybean oil was found to increase weight gain, body fat, diabetes, glucose intolerance and insulin resistance. Here too, soybean oil diets upregulated genes involved in diabetes, obesity, inflammation, mitochondrial function and cancer.

Ketogenic Diet Improves Insulin Sensitivity

Aside from fasting or time-restricted eating, a cyclical ketogenic diet is an effective way to improve your insulin sensitivity and reverse diabetes. A cyclical ketogenic diet — as detailed in my book “KetoFast” — shifts your body’s metabolic engine from burning carbohydrates to burning fats.

Your cells have the metabolic flexibility to adapt from using glucose for fuel to using ketone bodies, which come from the breakdown of fats, hence, the name “ketogenic.” Another term for this is nutritional ketosis. One of the fastest ways to prevent nutritional ketosis is by consuming sugar or refined carbohydrates.

A ketogenic diet calls for 50% to 70% of your daily calories to come from beneficial fats such as coconut oil, grass-pastured butter, organic pastured eggs, avocado or ketone producing fats like MCT oils, particularly C-8, while restricting your carbohydrates to 30 or 40 grams per day. Along with an appropriate amount of protein, this is typically enough to get you into ketosis.

Watch ‘Blood Sugar Rising’

“Blood Sugar Rising” provides an eye-opening glimpse into the very real struggles of Type 2 diabetics, as well as the around-the-clock challenges faced by those with Type 1 diabetes — a genetic condition in which your body produces no insulin at all — and groundbreaking inventions such as a bionic pancreas that automatically delivers the appropriate insulin dose as needed.

The film also reviews the real-world ramifications of skyrocketing insulin prices. The two types of diabetes differ in terms of their origin, and while insulin is typically ill advised for Type 2 diabetics,44 Type 1 diabetics die without it.

It also highlights the role of food as a cultural component, and how food-centered cultures can be guided to make healthier choices. For example, saying you have to abstain from rice, pasta or potatoes can be nearly impossible in certain families and cultures. Instead, you may need to approach it in terms of better and worse ways of preparing these foods, and restricting the amounts.

Diabetes, or more accurately insulin resistance with metabolic inflexibility, is a health accident waiting to happen, but it’s important to realize that you have control and can do something about it. In virtually all cases, it will require making more or less drastic changes to your diet and lifestyle, but the payoff goes beyond preventing diabetes. Concomitant with that, you’re also protecting your vision and lowering your risk of most of the chronic diseases that lead to an early grave.

Want to Defeat Coronavirus? Address Diabetes and Hypertension


Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2020/04/13/how-to-defeat-coronavirus.aspx

Analysis by Dr. Joseph Mercola    Fact Checked
April 13, 2020
Video not available at this site. To view, please go to original site above.
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how to defeat coronavirus

STORY AT-A-GLANCE

  • In Italy, more than 99% of fatalities from COVID-19 occurred among people who had underlying medical conditions
  • The finding came from an examination of 18% of Italy’s COVID-19 deaths, which revealed that only three people who died — or 0.8% — had no underlying conditions
  • Among Italy’s COVID-19 fatalities, 76.1% had high blood pressure, 35.5% had diabetes and 33% had heart disease
  • Underlying health conditions like heart disease and diabetes are linked to “poorer clinical outcomes,” such as admission to an intensive care unit (ICU), a need for invasive ventilation or death, among COVID-19 patients
  • To beat COVID-19, one of the best strategies is to get your underlying chronic conditions under control; even diabetes and high blood pressure can often be reversed via healthy diet and lifestyle

While the World Health Organization has put the death rate from novel coronavirus, COVID-19, at 3.4%,1 a study in Nature Medicine put it much lower, at 1.4%.2 The fact is, with many cases going unreported and untested, mild and asymptomatic cases may not be included in official COVID-19 death rate figures, which could skew the death rate significantly, making it appear higher than it actually is.

In Italy, however — the “new” epicenter for COVID-19 — the number of deaths reportedly overtook those in China by mid- to late March 2020.3

As the home to the world’s second-oldest population after Japan, Italy’s elderly population is at increased risk of death from COVID-19, but there’s another factor that also makes you more susceptible to death or serious illness if you contract COVID-19: an underlying health condition, particularly diabetes or high blood pressure.

This is why, if you want to stay healthy in this pandemic, one of the best strategies is to get your underlying chronic conditions under control; even diabetes and high blood pressure can often be reversed via healthy diet and lifestyle.

99% of COVID-19 Deaths in Italy Had Underlying Conditions

According to a study by The Istituto Superiore di Sanità, Italy’s national health authority,4 more than 99% of fatalities from COVID-19 occurred among people who had underlying medical conditions.

The finding came from an examination of 18% of Italy’s COVID-19 deaths, which revealed that only three people who died — or 0.8% — had no underlying conditions. On the contrary, nearly half the victims had three underlying conditions while one-fourth had one or two.5

Further, among the fatalities, 76.1% had high blood pressure, 35.5% had diabetes and 33% had heart disease.6 While the median age of those infected was 63, most deaths occurred in older people, with 79.5 being the average age of those who’ve died. Among those who were under 40 when they died, all had serious underlying health conditions.7

A report of the WHO-China Joint Mission on COVID-19, released in February 2020, similarly found a higher crude fatality ratio (CFR) among people with additional health conditions. While those who were otherwise healthy had a CFR of 1.4%, those with comorbid conditions had much higher rates, as follows:8

  • Cardiovascular disease — 13.2%
  • Diabetes — 9.2%
  • High blood pressure — 8.4%
  • Chronic respiratory disease — 8%
  • Cancer — 7.6%

Underlying Conditions, Obesity Increase Risk of Poor Outcomes

Another study looking into the impact of co-existing health conditions like high blood pressure, heart disease and diabetes on COVID-19 outcomes found they’re linked to “poorer clinical outcomes,” such as admission to an intensive care unit, a need for invasive ventilation or death.9

The study involved 1,590 laboratory-confirmed hospitalized patients, revealing that people with a chronic condition were 1.8 times more likely to have a poor outcome compared to those with none. This jumped to 2.6 times more likely for those with two chronic conditions.10

The first review of fatal COVID-19 cases in China also found diabetes may be associated with mortality,11 as did a report of 72,314 cases by the Chinese Center for Disease Control and Prevention.12

While the researchers found a mortality rate of 2.3% in the overall population, this rose to 10.5% among people with cardiovascular disease and 7.3% among those with diabetes.13 Likewise, in a Lancet study of 191 patients in China, 48% of those who died from COVID-19 had high blood pressure.14,15

Likewise, the Intensive Care National Audit and Research Centre released a report on 196 patients critically ill with COVID-19.16 Among them, 56 patients had a body mass index (BMI) of 25 to 30, which is classified as overweight, 58 had a BMI of 30 to 40, which indicates obesity, and 13 had a BMI of 40 or higher which is classified as severely obese. Overall, 71.7% of the critical patients were overweight, obese or severely obese.17

This could have serious implications for the U.S., where approximately 45%, or 133 million, people suffer from at least one chronic disease.18 Among them, more than 1 in 10 have diabetes (and another 1 in 3 has prediabetes),19 while 108 million adults have high blood pressure.20 Further, 71.6% of U.S. adults aged 20 and over are overweight or obese.21

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Ultimate guide to combatting coronavirus


Are ACE Inhibitors Part of the Problem?

In another intriguing finding, researchers from the University of Basel in Switzerland noted that in three studies of patients with COVID-19, the most frequent underlying conditions — heart disease, diabetes and hypertension — are those often treated with angiotensin-converting enzyme (ACE) inhibitors.22 Writing in The Lancet Respiratory Medicine, they explained:

“Human pathogenic coronaviruses (severe acute respiratory syndrome coronavirus [SARS-CoV] and SARS-CoV-2) bind to their target cells through angiotensin-converting enzyme 2 (ACE2), which is expressed by epithelial cells of the lung, intestine, kidney, and blood vessels.

The expression of ACE2 is substantially increased in patients with type 1 or type 2 diabetes, who are treated with ACE inhibitors and angiotensin II type-I receptor blockers (ARBs). Hypertension is also treated with ACE inhibitors and ARBs, which results in an upregulation of ACE2.”23

In short, the ACE2 enzyme is beneficial in that it promotes tissue regeneration, and ACE inhibitors and ARBs (as well as ibuprofen) increase the formation of ACE 2. The problem is that coronavirus binds to ACE2 and uses it to enter cells, where it then multiplies. “For that reason,” study author Michael Roth said in a news release, “we suggest further research into the use of these drugs in COVID-19 patients.”24

Targeting Insulin Resistance Is Key

The likely common denominator for these diseases is our old nemesis, insulin resistance, in response to a high-carbohydrate and processed food diet. Insulin resistance not only contributes to these diseases but also impairs immune function. So, if your fasting blood sugar is over 100 it would be highly prudent to make diligent efforts to get that under control.

As your insulin and leptin levels rise, it causes your blood pressure to increase. Eventually, you may become insulin and/or leptin resistant. Likewise, Type 2 diabetes is a disease of insulin resistance resulting in high blood sugar.

When your body is insulin resistant,25 the cells in your body do not respond well to insulin, which lowers their ability to use glucose from the blood for energy. The pancreas secretes more insulin, trying to overcome the cells’ weak response in their attempt to keep blood glucose levels in a healthy range.

As noted by Dr. Sandra Weber, president of the American Association of Clinical Endocrinologists, in The New York Times, “We know that if you do not have good glucose control, you’re at high risk for infection, including viruses and presumably this one [COVID-19] as well … [improving glucose control] would put you in a situation where you would have better immune function.”26

What and When to Eat to Beat Insulin Resistance

With regard to insulin resistance, research shows intermittent fasting promotes insulin sensitivity and improves blood sugar management by increasing insulin-mediated glucose uptake rates.27 This is important not only for resolving Type 2 diabetes but also high blood pressure and obesity.

Time restricted eating, i.e., the restriction of eating only during a six- to eight-hour window, mimics the eating habits of our ancestors and restores your body to a more natural state that allows a whole host of metabolic benefits to occur.28 While there are a number of different intermittent fasting protocols, my preference is fasting daily for 18 hours and eating all meals within a six-hour window.

If you’re new to the concept of time-restricted eating, consider starting by skipping breakfast and having your lunch and dinner within a six-hour timeframe, say 11 a.m. and 5 p.m., making sure you stop eating three hours before going to bed. It’s a powerful tool that can work even in lieu of making other dietary changes.

In one study, when 15 men at risk of Type 2 diabetes restricted their eating to a nine-hour window, they lowered their mean fasting glucose, regardless of when the “eating window” commenced.29

What you eat is also important. I recommend adopting a cyclical ketogenic diet, which involves radically limiting carbs (replacing them with healthy fats and moderate amounts of protein) until you’re close to or at your ideal weight, ultimately allowing your body to burn fat — not carbohydrates — as its primary fuel.

Key Steps to Getting — and Staying — Healthy

While many people — young and old alike — are facing Type 2 diabetes, obesity and high blood pressure, these conditions can be turned around, and in so doing you’ll significantly reduce your risk of becoming seriously ill from COVID-19.

Along with intermittent fasting and a cyclical ketogenic diet, the tips that follow will help you prevent and reverse obesity, Type 2 diabetes and high blood pressure, while helping you boost your immune system to avoid both chronic diseases and illness from infectious agents alike:

Limit added sugars to a maximum of 25 grams per day. If you’re insulin resistant or diabetic, reduce your total sugar intake to 15 grams per day until your insulin/leptin resistance has resolved (then it can be increased to 25 grams) and start intermittent fasting as soon as possible.
Limit net carbs (total carbohydrates minus fiber) and protein and replace them with higher amounts of high-quality healthy fats such as seeds, nuts, raw grass fed butter, olives, avocado, coconut oil, organic pastured eggs and animal fats, including animal-based omega-3s.
Avoid all processed foods, including processed meats. For a list of foods that are particularly beneficial for diabetics, please see “Nine Superfoods for Diabetics.”
Get regular exercise each week and increase physical movement throughout waking hours, with the goal of sitting down less than three hours a day.

Healthy middle-aged adults were able to improve their insulin sensitivity and blood sugar regulation after just two weeks of interval training (three sessions per week),30 while among people with Type 2 diabetes, just one interval training session was able to improve blood sugar regulation for the next 24 hours.31

Your body’s ability to respond to insulin is also affected by just one day of excess sitting, which leads your pancreas to produce increased amounts of insulin. Research published in Diabetologia also found that those who sat for the longest periods of time were twice as likely to have diabetes or heart disease, compared to those who sat the least,32 so make sure to keep moving.

Get sufficient sleep — Most need right around eight hours of sleep per night. Research has shown sleep deprivation can have a significant bearing on your insulin sensitivity33 and immune function.
Optimize your vitamin D level, ideally through sensible sun exposure. If using oral vitamin D3 supplementation, be sure to increase your intake of magnesium and vitamin K2 as well, as these nutrients work in tandem, and monitor your vitamin D level.
Optimize your gut health by regularly eating fermented foods and/or taking a high-quality probiotic supplement.
Stress management should be a regular part of your immune-support and hypertension-reduction plan, as hypertension often has an emotional component to it, especially if you’re chronically stressed or anxious. Using the Emotional Freedom Techniques (EFT) is one excellent suggestion.
– Sources and References

Can glutathione help combat fatty liver disease?

Reproduced from original article:
www.naturalhealth365.com/glutathione-liver-disease-3311.html

glutathione-detox(NaturalHealth365) Glutathione – a powerful antioxidant that’s found within every cell of the body – is made up of amino acids. This antioxidant contributes to a variety of important bodily functions, including vitamin regeneration, breaking down free radicals, immune system support, helping the liver to handle fats, making DNA, and even the creation of sperm cells.  But, unlike many other antioxidants, the body is actually able to make this substance in your liver.

Researchers have previously found links between certain diseases and low glutathione levels.  Since the antioxidant plays an important role in the antioxidant and detoxification systems of cells, scientists hypothesized that glutathione supplementation would help combat fatty liver disease.  And in a fairly recent study, researchers investigated oral supplementation in individuals with nonalcoholic fatty liver disease (NAFLD) with positive results.

The proper amount of glutathione proves to be beneficial for people with fatty liver disease

The study involved 34 patients with nonalcoholic fatty liver disease, all of whom had been diagnosed via ultrasonography. First, patients underwent lifestyle interventions, such as diet and exercise changes for a period of three months.

Then, patients were treated with 300 mg per day of glutathione. Clinical parameters like liver fat, liver fibrosis, and alanine aminotransferase (ALT – a blood test that checks for liver damage) levels were all checked both before and after treatment with glutathione.

Among the patients who finished this protocol, a significant decrease in ALT levels were seen after treatment with glutathione.  Patients also so decreases in ferritin, triglyceride, and non-esterified fatty acid levels.

Overall, the study demonstrated that oral supplementation of glutathione does offer some significant potential therapeutic effects for patients with fatty liver disease, although study authors note that larger-scale clinical trials should be done for verification.

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Powerful antioxidant offers additional health benefits

Beyond this new study showing the benefits of glutathione for individuals with liver disease, the powerful antioxidant offers a number of additional health benefits as well.

Benefits include:

  • Counteracting free radicals: As an antioxidant, it helps fight free radicals, protecting your body from their damaging and aging effects.
  • Improves insulin sensitivity: One study showed that individuals who have insulin resistance often have low glutathione levels.
  • Combating cancer: Some research shows glutathione may help prevent cancer progression as well.
  • Alleviate symptoms of Parkinson’s: Research shows that maintaining healthy levels of glutathione may help alleviate or at least reduce symptoms associated with Parkinson’s disease.
  • Boosting the immune system: By protecting cell mitochondria and reducing inflammation, glutathione helps boost the immune system.

Although glutathione offers a number of proven health benefits, as you grow older, levels of glutathione decrease.  Injury, stress, and illness can all affect glutathione stores, as well.

Therefore, eating an organic diet, reducing or eliminating smoking and alcohol consumption, and avoiding exposure to environmental toxins can help prevent glutathione depletion.  Naturally, adding a glutathione supplement to your diet in the amount of 200 – 500 mg per day may also prove helpful, although you should always talk to your integrative physician before making any changes to your diet or supplement routine.

Sources for this article include:

NIH.gov
NaturalHealth365.com
MedicalNewsToday.com

Canned soup: “Comfort foods” that threaten your health

Reproduced from original article:
www.naturalhealth365store.com/canned-soup-dangerous-health

Posted by Jonathan Landsman 25th January 2020

It looks like such a healthy idea . . . a can of tomato or chicken noodle soup. Plus, there are all those associations we have with being fed a steaming bowl of soup on a TV tray while we lie in bed recovering from a horrible cold.

But, that may not be always so true.

Now, first let me say there is good news. Some organic brands of canned soup like Amy’s Organics are absolutely delicious and are way less toxic than more commercial brands.  Imagine Food’s organic soups are also on the list of safe soups to consume, as well as other organic brands like Wolfgang Puck’s.

Of course, if you really want the “best” kind of soup … nothing beats homemade from scratch.  Having said that, I’ll give you a list of healthy canned soups that are delicious, nutritious, and safe at the end of this article.

But, first, what’s so bad about canned soup?

BPA is an endocrine disruptor that can cause hormone-based cancers

Study after study has confirmed that canned soup is loaded with bisphenol-A or BPA, for short. BPA is an endocrine disruptor that throws our hormones completely out of balance and can cause estrogen dominance, which can lead to the development of breast cancer, uterine and endometrial cancer, and prostate cancer.

BPA is also terrible for bone health

BPA blocks calcium channels, preventing calcium from making it into the bone, where you need it to give your bones strength and resilience to breakage. A recent article published in the International Journal of Medical Science found that BPA blocks calcium absorption at a cellular level.

Canned soup contains too much sodium, making it a threat to kidney health

Just one can of soup can contain as much as one third of your RDA for sodium! Light soups often have even more sodium added in the manufacturer’s efforts to give the soup more flavor.

Individuals with insulin resistance, diabetes, and cardiovascular disease who are trying to avoid sodium definitely want to avoid canned soup for this reason. Persons trying to stay in good health should steer clear of soups containing too much sodium as well.

Canned soup is loaded with MSG – a major cause of diabetes and insulin resistance

Scientists have now linked MSG with insulin resistance, obesity, and possibly type 2 diabetes. In fact, in China today, diabetes is becoming an epidemic, and scientists believe additives like MSG and adopting a chiefly Western diet full of fast food and processed foods could be largely to blame.

Safe brands of canned soup include:

  • Amy’s Organic Soups
  • Wolfgang Puck’s Organic Soup
  • Imagine Food’s Organic Soups
  • Pacific Food’s Organic and Organic Bone Broth Soups

Editor’s note: The NaturalHealth365 Store offers the finest quality (immune-supportive) supplements on the market.  Click here to shop today.

Sources for this article include:

NIH.gov

Saveourbones.com