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What Your Heart Rate Variability Tells You About Your Health


Reproduced from original article:
https://fitness.mercola.com/sites/fitness/archive/2020/02/14/heart-rate-variability.aspx

Analysis by Dr. Joseph Mercola     

heart rate variability

STORY AT-A-GLANCE

  • Your heart rate variability (HRV) is a measure of the variations in time elapsed between your heartbeats, and is representative of your heart’s ability to respond to physiological and environmental stressors
  • A healthy heart rhythm is not perfectly even. When your heartrate is monotonously regular, your HRV will be low. Low HRV is associated with autonomic nervous system (ANS) impairment, which reduces your body’s ability to cope with stressors
  • When your HRV is high, the intervals between heartbeats is large and irregular, and this is an indication of augmented resilience against stress. High HRV is also indicative of greater cardiovascular fitness
  • Research shows the parasympathetic activity of patients with ischemic heart disease is one-third lower, on average, than that of a healthy individual, and low HRV is a strong and independent predictor of mortality after an acute myocardial infarction
  • High blood pressure, smoking, diabetes and stress decrease your parasympathetic activity, thus raising your risk of a cardiac event. Factors that upregulate your parasympathetic nervous system and protect your heart include dietary nitrates that stimulate nitric oxide production and foods or supplements that stimulate acetylcholine production, such as eggs and other choline-rich foods

Your heart rate variability (HRV) is a measure of the variations in time elapsed between your heartbeats, and is representative of your heart’s ability to respond to physiological and environmental stress stimuli.1,2,3,4,5

Contrary to what might seem logical at first glance, a healthy heart rhythm is not perfectly even. When your heartrate is “monotonously regular,” your HRV will be low. Low HRV is associated with autonomic nervous system (ANS) impairment,6 which reduces your body’s ability to cope with stressors, be they internal or external.

As such, HRV is a good stress indicator. When your HRV is high, the intervals between heartbeats is “large and irregular,” and this is an indication of augmented resilience against stress.7 High HRV is also indicative of greater cardiovascular fitness.8

Some experts now believe HRV may actually be one of the most important biomarkers of cardiovascular health, even more so than standard testing like cholesterol, C-reactive protein and even blood pressure.9

Indeed, as detailed in Dr. Thomas Cowan’s guest article about the real cause of heart attacks, published in 2014, increasing our understanding of the role of the autonomic nervous system in the development of ischemia (inadequate blood flow to the heart) — and how we can use HRV as a measure of risk — could revolutionize the prevention and treatment of heart disease. We’re inching ever closer to that as time goes on.

HRV and Your Autonomic Nervous System

As you probably know, you have two distinct nervous systems:

  1. The central nervous system (CNS), which controls conscious muscle and nerve functions
  2. The autonomic nervous system (ANS), which controls the unconscious function of your internal organs

Your ANS is crucial for optimal health, as it controls things like breathing, heart rate, sweating, digestion and the general functioning of your internal organs. If your ANS is dysfunctional or blocked, you’re bound to experience health problems.

There are any number of factors that can cause your ANS to not function properly. Examples include but are not limited to the following. To determine whether one or more of the factors listed below are affecting your ANS, you would perform a stress or challenge test to see how the suspected factor affects your HRV.

Food allergies Psychological and/or spiritual issues
Dehydration Heavy metal toxicity
Nutritional deficiencies Infections
Geopathic field stress Electromagnetic field stress
Structural problems Scars
Synthetic clothing, underwire bras and jewelry such as glasses and watches Pesticide and herbicide exposure
Prosthetics Visual problems

ANS Imbalance May Be a Key Factor in Your Heart Disease

Your ANS is further divided into two branches, namely your:

1.Sympathetic nervous system (SNS) — This system, also known as “fight or flight,” is centered in your adrenal medulla and uses adrenaline to ready your body for action in response to perceived threat. A series of biochemical responses are thus triggered, including glycolytic pathways that accelerate the breakdown of glucose for a rapid energy boost.

2.Parasympathetic nervous system (PNS) — This branch, known as the “rest and digest” arm of the ANS (relaxation response), is centered in your adrenal cortex. Its chemical mediators include acetylcholine, nitric oxide and cyclic guanosine monophosphate (cGMP).

Your PNS plays a central role in alleviating the stress response.10 When your HRV is low and your PNS is inhibited, you’re more vulnerable to the detrimental effects of future stress.11

Your vagus nerve, which is part of the parasympathetic chain, modulates your heart activity, slowing your heartbeat and relaxing your heart when your PNS is activated. When your SNS is activated, your vagus nerve will accelerate your heartbeat and cause constriction in your heart muscle.

When you’re healthy, these two branches of your ANS — the SNS and PNS — are well-balanced yet in a “ready” state. According to Cowan, an imbalance in your SNS and PNS is responsible for the vast majority of heart disease.

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HRV Measures Your ANS Status

By monitoring your HRV, you can get a clear idea of your ANS status in real time. Again, the reason for this is because your ANS controls your heart rhythm. Research12 published in 2004 shows the parasympathetic activity of patients with ischemic heart disease is one-third lower, on average, than that of a healthy individual. As explained in the abstract:13

“About three quarters of myocardial ischemic events are triggered by the autonomic nervous system. The pathognomonic constellation is a combination of an almost complete withdrawal of tonic vagal activity with increased sympathetic activity.

The reduction of tonic vagal activity, which is characteristic for ischemic heart disease, and the acute withdrawal of vagal drive preceding the onset of ischemia are not dependent on coronary artery disease.

In this paper, the pathophysiological steps that lead from sympathetic-parasympathetic imbalance to myocardial ischemia shall be discussed. A considerable increase of aerobic glycolysis within the myocardium as a result of the autonomic imbalance is of special importance in this process.”

As a general rule, the worse your ischemia is, the lower your parasympathetic activity will be.14 As noted in the 2004 study above, a vast majority of ischemic events are preceded by a drastic reduction in parasympathetic activity in conjunction with increased sympathetic activity, brought on by strenuous physical activity or emotional shock, for example.15

In stark contrast, people with normal parasympathetic activity who experience an abrupt increase in sympathetic activity do not suffer from ischemia.

So, to summarize, in order for you to have a heart attack, you must experience both a drastic decrease in parasympathetic activity and an increase in sympathetic activity. In the absence of those two simultaneous factors, you’re unlikely to have a heart attack.

Vagus Flow Nearly Stops Before and During Ischemic Events

This flies in the face of conventional thought that says heart attacks are simply the result of one or more blocked arteries. But as noted in the 2004 study above, “the acute withdrawal of vagal drive preceding the onset of ischemia are not dependent on coronary artery disease.” In other words, your likelihood of having a heart attack is not dependent on having blocked arteries.

Instead, your heart attack risk is primarily dependent on the functioning of your ANS. Studies have also shown your risk of actually dying from a heart attack is significantly increased if your HRV is low. In fact, low HRV has been shown to be a “strong and independent predictor of mortality after an acute myocardial infarction.”16

An earlier study17 by the same author, this one published in 1997, looked at the role of ANS activity before and during transient ischemic events, using HRV measurements. As noted in this paper:

“With two exceptions, all ischemic episodes were preceded by an acute almost complete suppression of respiratory sinus arrhythmia. During the entire ischemic episode, HRV stayed at this reduced level, and preceding the end of the ischemia, it increased again.

This suppression of intrinsic heart period variations reflects an almost complete withdrawal of modulated vagal outflow immediately before and during ischemic episodes.”

The take-home message here is that while we all experience times of excess sympathetic activity (fight-or-flight mode), thanks to the stresses of daily life, shocks to your system only become dangerous to your health when your parasympathetic activity (relaxation response) is suppressed for a long period of time.

Factors that decrease vagal activity include high blood pressure, smoking and diabetes, while physical and emotional stress decrease your parasympathetic activity.18 All of these factors, then, contribute to heart problems and raise your risk of a cardiac event.

On the flip-side, factors that upregulate your PNS include dietary nitrates that stimulate nitric oxide production and foods or supplements that stimulate acetylcholine production, such as eggs and other choline-rich foods.19

HRV as an Objective Indicator of Stress and Mental Health

HRV does more than measure and predict your heart health, though. As explained in a review paper20 published in Psychiatry Investigation in 2019, SNS hyperactivation caused by chronic stress can cause “physical, psychological, and behavioral abnormalities,” and HRV can be used as a psychological stress indicator and an objective assessment tool of mental health.

The paper reviews 37 publications where HRV reactivity was used as an objective psychological stress measure. According to the authors:21

“In most studies, HRV variables changed in response to stress induced by various methods. The most frequently reported factor associated with variation in HRV variables was low parasympathetic activity …

Neuroimaging studies suggested that HRV may be linked to cortical regions (e.g., the ventromedial prefrontal cortex) that are involved in stressful situation appraisal.”

The Three-Stage Stress Response Model in Clinical Practice

The Psychiatry Investigation paper also presents a three-stage stress response model, and explains how HRV can be used in a clinical setting to assess a patient’s overall health and disease risk:22

“The first stage is the ‘alarm reaction stage,’ in which the body reacts to a stressor with the fight-or-flight response and activates the SNS. The second stage is the ‘resistance stage,’ in which the body adapts to the stressor. During this stage, the PNS restores many physiological functions to normal, while the body focuses its resources against the stressor.

Although the outward appearance of the organism seems normal, blood glucose, cortisol, and adrenalin levels remain elevated. If a stressor continues beyond the body’s capacity to cope, the organism exhausts its resources, making it susceptible to disease or death. This ‘exhaustion stage’ is reached when the acquired adaptation or resistance is lost.

When assessing the severity of a patient’s stress level in a clinical setting, HRV results should be interpreted with this three-stage process in mind. At each stage, stress causes changes in physiological function, which are reflected in HRV changes.

Due to the variety of potential stressors and individual stress responses, it is essential to understand the overall autonomic context and examine a patient’s medical and psychological history when interpreting the relationship between HRV and stress.”

HRV and Inflammation

Your HRV can also give you an idea of your inflammation levels. Inflammation, of course, is a hallmark of cardiovascular disease, but most other chronic diseases involve elevated inflammation levels as well. As noted in a 2013 review paper in Frontiers of Physiology:23

“Many experimental and clinical studies have confirmed a continuous cross-talk between both sympathetic and parasympathetic branches of autonomic nervous system and inflammatory response, in different clinical scenarios.

In cardiovascular diseases, inflammation has been proven to play a pivotal role in disease progression, pathogenesis and resolution.

A few clinical studies have assessed the possible inter-relation between neuro-autonomic output, estimated with heart rate variability analysis, which is the variability of R-R in the electrocardiogram, and different inflammatory biomarkers, in patients suffering from stable or unstable coronary artery disease (CAD) and heart failure.

Moreover, different indices derived from heart rate signals’ processing, have been proven to correlate strongly with severity of heart disease and predict final outcome.”

As explained in this paper, both the SNS and PNS are powerful modulators of inflammation. When the two are properly balanced, they promote an anti-inflammatory landscape.

HRV and Your Overall Health

Low HRV has been linked to a range of diseases, either by promoting inflammation or via other mechanisms. It’s also been shown to be a reliable predictor of disease progression.24

Diabetes, for example, is a risk factor for heart disease and stroke, and being able to detect the early signs of complications can go a long way toward lowering your risk of death. HRV can be a valuable tool in this regard.

As reported in a 2018 paper,25 “A systematic review of those with diabetes concluded that HRV can help to predict cardiac morbidity and mortality, and that it can be used at an early stage to indicate the future risk of complications.”

This paper also points out that “a reduction in HRV predicts macrovascular disease, for example carotid artery atherosclerosis,” and “is associated with a significantly increased risk of death from cardiovascular disease.”

Interestingly, the authors also review a number of studies looking at how various foods and diets affect your HRV, concluding that tracking your HRV may be a helpful tool “when examining the impact of what we eat.”

How to Check Your HRV

So, how do you check your HRV? Harvard University offers the following suggestions:26

“The gold standard is to analyze a long strip of an electrocardiogram … But over the past few years, several companies have launched apps and heart rate monitors that do something similar.

The accuracy of these methods is still under scrutiny, but … the technology is improving substantially … The easiest and cheapest way to check HRV is to buy a chest strap heart monitor … and download a free app (Elite HRV is a good one) to analyze the data.

The chest strap monitor tends to be more accurate than wrist or finger devices. Check your HRV in the mornings after you wake up, a few times a week, and track for changes as you incorporate healthier interventions.”

Keep in mind that using a chest strap heart monitor in combination with a cellphone app exposes you to Bluetooth EMF frequencies, which makes it less than optimal.

The HRV4Training app27,28 claims to accurately calculate HRV even without an external sensor or chest strap (although it can also be integrated with Apple Watch and the Oura ring), and has research29 that backs it up. With this app, you can simply use your phone camera to get a measure of your HRV.

By collecting your HRV data at different times over the course of weeks, you can start to get a picture of how your body responds to stress, and identify the activities or situations that raise and lower it.

It’s also really useful for athletes, as it can tell you whether you’ve sufficiently recovered or are pushing yourself too hard. A high HRV is a sign that your body is handling the stress well, whereas a low HRV indicates your body is under stress, which can make you more prone to ill health if you keep pushing.

How to Improve Your HRV

If your HRV is consistently subpar, don’t fret. There are many ways to improve your HRV, and most are inexpensive or free. Strategies that can improve your HRV include:30,31

Rest and sleep Mindfulness and other forms of meditation
Exercise Green tea
Avoiding procrastination Avoiding excess work and extensive commutes, and minimize work-related stress
Practicing forgiveness Yoga
Music Breathing exercises
Spending time outdoors, in nature Optimizing your omega-3 level

 

Beyond Curcumin: Why Turmeric Is Not the Same as Curcumin

© 28th January 2020 GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here www.greenmedinfo.com/greenmed/newsletter
Reproduced from original article:
https://www.greenmedinfo.com/blog/beyond-curcumin-why-turmeric-not-same-curcumin

Posted on:  Tuesday, January 28th 2020 at 10:30 am

When hearing about turmeric, curcumin gets all the glory, but this ancient healing root contains other impressive compounds too, like turmerosaccharides. If you haven’t heard of them before, here’s why you should

Turmeric is a hot topic here at GreenMedInfo.com. For example, you can read about how Science Confirms Turmeric As Effective As 14 Drugs600 Reasons Turmeric May Be the World’s Most Important Herb and even How WHOLE Turmeric Heals the Damaged Brain.

Yet, here’s what most people — even health and nutrition enthusiasts — often don’t realize. Despite the two often being referred to interchangeably, turmeric is actually far different than the popular supplement ingredient curcumin.

Sure, curcumin is derived from turmeric, but when it comes to their uses, benefits and bioavailability, the differences between turmeric and curcumin are quite significant, and in this article you’ll discover exactly why, and why you may want to think beyond curcumin when it comes to using turmeric in your diet.

Turmeric Versus Curcumin

Turmeric is just a root, and technically the root of Curcuma longa, which is a flowering plant of the ginger family. It contains many bioactive plant substances, but one particular group, the curcuminoids, are often touted as possessing the biggest health-promoting bang-for-your-buck. These curcuminoids include demethoxycurcumin, bisdemethoxycurcumin and — you guessed it — curcumin.

But curcumin is only present at about 2% to 8% concentration in the average turmeric preparation.[i] Curcumin is well-known for its anti-inflammatory, anti-carcinogenic and antioxidant effects, but if curcumin is all that you’re relying on for the benefits of curcumin, you’re technically missing out on 92% to 98% of the other plant bioactive compounds in the whole turmeric root.

Don’t feel bad about being on the curcumin bandwagon. After all, curcumin is the most studied curcuminoid and is also the most abundant curcuminoid found in turmeric.

The Problem With Curcumin

But there’s a problem. Despite its wide array of potential benefits, the actual bioavailability of curcumin in humans and animals is quite low. Curcumin also has a high rate of metabolization and rapid systemic clearance.

So getting enough curcumin into your system to reach blood levels sufficient to exert the benefits shown in research requires consuming around 3 to 5 teaspoons of turmeric powder a day. And that’s a lot of turmeric, along with posing a high risk of having a constantly yellowish-orange stained mouth.

Even then, curcumin is so poorly absorbed that it often needs to be combined with something that can increase its bioavailability. One quite popular example of this is an extract found in black pepper. On many supplement labels, you’ll see listed a patented extract obtained from black pepper fruits called BioPerine, which is commonly used as a curcumin bioavailability enhancer.

Another strategy to increase the bioavailability of curcumin is via the use of phytosomes, which are plant extracts that are bound to phosphatidylcholine. Once attached to phosphatidylcholine, there is much higher absorption of curcumin (up to 30 times more bioavailability).

Finally, we get to the biggest problem with curcumin: if you’re relying on it as your only source to obtain the benefits of turmeric, then you’re missing out on other components of this impressive root.

Beyond Curcumin

I don’t quite understand why we seem to myopically focus on curcumin in the health, nutrition and supplement industry.

After all, the entire turmeric rhizome has been used in Ayurvedic medicine for over 4,000 years, and during most of this time there was no fancy technology such as a patented Bioperine extract or phosphatidylcholine molecules in supplement form to increase bioavailability of the curcumin, nor was there technology to extract appreciable amounts of curcumin from the turmeric.

Instead, turmeric’s long history of culinary, medicinal and cosmetic use in India includes water-based preparations for internal use (known as Kashaya), fat-based (oil, ghee) preparations for internal use (known as Sneha), and powder preparation for internal use (known as Churna). Consider this anecdote from the book “Herbal Medicine: Biomolecular and Clinical Aspects”:

“The use of turmeric dates back nearly 4000 years to the Vedic culture in India, where it was used as a culinary spice and had some religious significance. It probably reached China by 700 ad, East Africa by 800 ad, West Africa by 1200 ad, and Jamaica in the eighteenth century. In 1280, Marco Polo described this spice, marveling at a vegetable that exhibited qualities so similar to that of saffron.

According to Sanskrit medical treatises and Ayurvedic and Unani systems, turmeric has a long history of medicinal use in South Asia. Susruta’s Ayurvedic Compendium, dating back to 250 bc, recommends an ointment containing turmeric to relieve the effects of poisoned food.”

You can read more about turmeric’s journey from traditional to modern medicine in “Herbal Medicine: Biomolecular and Clinical Aspects”.[ii]

If these ancient healers have been harnessing the power of turmeric via fresh juice, teas, tinctures and powders, as well as using it topically in the form of creams, lotions, pastes and ointments, then why has most of the research up until very recently been centered around the curcuminoids — which, as mentioned, are a fraction of 2% to 8% of the plant?

These traditional healing and food practices related to the use of turmeric indicate that it’s not just the curcuminoid component of turmeric that is likely to possess physiological benefits. Enter turmerosaccharides.

Turmerosaccharides are water-soluble bioactive polysaccharides extracted from that remaining 90+% percent of the turmeric root. The fact that turmerosaccharides are water-soluble means that all of the good stuff is more easily absorbed into the tissues of your body and metabolized more quickly than the curcumin-based fat-soluble components of turmeric.

How Turmerosaccharides Work

The first property of turmerosaccharides that makes them more desirable is the fact that they are naturally water-soluble. Through a steam extraction process, turmerosaccharides are isolated from the turmeric oil, without the need for using any harsh solvents. This means the bioavailability of turmerosaccharides is significantly higher than that of curcumin.

In addition, the effects of tumerosaccharides on your body are astounding, especially if you’re active or suffer from soreness from overexertion. A 2013 study found that turmerosaccharides reduced joint tenderness, crepitation, swelling and effusion related to overuse, while increasing joint function and flexibility.[iii] Patients with primary knee osteoarthritis received either turmerosaccharides, glucosamine sulfate, a combination of turmerosaccharides and glucosamine sulfate, or a placebo for 42 days. The efficacy of the different treatments was assessed during the treatment period, on both day 21 and day 42 of the study.

The analysis of post-treatment scores following the administration of turmerosaccharides at each clinical visit showed a significant decrease in joint issues compared to the placebo. The turmerosaccharides-treated group also showed a significant decrease in the use of their standard medication, along with clinical and subjective improvement compared to placebo.

Another study investigated turmerosaccharides’ effect on human knee cartilage and found that it protects cartilage homeostasis,[iv] which means that it balances out the natural rate of synthesis and degradation, keeping joints happily balanced. Interleukin 1 beta (a natural protein involved with inflammation) and hydrogen peroxide (which is generally toxic to cells) are both bad news bears for chondrocytes, which are your cartilage-producing cells.

This study looked at the effects of turmerosaccharides by exposing these chondrocytes to these toxins with and without turmerosaccharides, then measuring markers indicating cell degradation, aging and death, as well as cartilage creation, degradation and general inflammation.

The presence of turmerosaccharides decreased cartilage cell destruction and general inflammation in the knee cartilage cells, and also protected compounds that improve cartilage creation, such as glycosaminoglycans and type II collagen.

In other studies, turmerosaccharides were shown to significantly reduce acute and chronic inflammation and support a balanced inflammatory response[v] as well as increase gene expression of type II collagen.[vi]

Where Can You Find Turmerosaccharides?

So by now, you’re probably wondering where you can actually get turmerosaccharides. One easy option would be to find high-quality turmeric root grown in clean soil, and then boil it in water, preferably via a decoction method, which involves a long simmering process in hot water, and can work quite well for a variety of hard, woody herbs and spices, such as roots, bark and stems.

Another option is to look for nutritional supplements that contain Turmacin® — which is a water-soluble extract of turmeric that contains high amounts of turmerosaccharides. And there’s absolutely no reason that you can’t co-consume turmerosaccharides along with curcumin to get even more benefits out of the wonderful turmeric root.

For more on turmeric, curcumin and other ancestral and modern scientific ways to enhance recovery and decrease inflammation, you can read Chapter 14 of my new book “Boundless”, which tackles more on healing the body more quickly from injuries, inflammation and hard workouts.


References

[i] Biofactors. 2013 Jan-Feb;39(1):78-87. doi: 10.1002/biof.1074. Epub 2013 Jan 22.

[ii] Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Chapter 13, Turmeric, the Golden Spice

[iii] Inflammopharmacology. 2013 Apr;21(2):129-36. doi: 10.1007/s10787-012-0163-3. Epub 2012 Dec 16.

[iv] Inflammopharmacology. 2018 Oct;26(5):1233-1243. doi: 10.1007/s10787-017-0433-1. Epub 2018 Jan 8.

[v] Antiinflamm Antiallergy Agents Med Chem. 2015;14(1):53-62.

[vi] Inflammopharmacology. 2018 Oct;26(5):1233-1243. doi: 10.1007/s10787-017-0433-1. Epub 2018 Jan 8.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.

More Health Benefits of Quercetin Revealed


Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2020/01/27/quercetin-benefits.aspx
Analysis by Dr. Joseph Mercola     Fact Checked image

January 27, 2020
quercetin benefits

STORY AT-A-GLANCE

  • Quercetin has been shown to combat inflammation and acts as a natural antihistamine. Several studies have highlighted quercetin’s ability to prevent and treat both the common cold and influenza
  • Another, less known benefit and use for quercetin includes the prevention and/or treatment of high blood pressure, cardiovascular disease, metabolic syndrome, certain cancers, gout, arthritis and mood disorders
  • A review of quercetin’s effect on metabolic syndrome found it significantly reduced fasting plasma glucose when taken for at least eight weeks at a dosage of 500 milligrams per day or more
  • Other recent research found quercetin has a beneficial impact on nonalcoholic fatty liver disease by ameliorating inflammation, oxidative stress and lipid metabolism
  • Quercetin also has the ability to trigger tumor regression by interacting with your DNA and activating the mitochondrial pathway of apoptosis (the programmed cell death of damaged cells)

Quercetin1 is an antioxidant flavonol found naturally in foods such as apples, plums, red grapes, green tea, elder flower and onions, just to name a few.2 According to a 2019 Market Watch report,3 the quercetin market is growing rapidly as its health benefits are becoming more widely known.

Quercetin has been shown to combat inflammation and acts as a natural antihistamine. In fact, its antiviral capacity appears to be the primary focus of many studies looking at quercetin’s benefits, and a number of studies have highlighted quercetin’s ability to prevent and treat both the common cold and influenza.4,5,6,7

But there are also other, less known benefits and uses for this supplement, including the prevention and/or treatment of:8

High blood pressure9 Cardiovascular disease10
Metabolic syndrome11 Certain kinds of cancer12
Nonalcoholic fatty liver disease (NAFLD)13 Gout14
Arthritis15 Mood disorders16
Longevity, thanks to its senolytic benefits (clearing out damaged and worn-out cells)17,18

Additionally, quercetin is also helpful for aluminum-induced neurodegenerative changes, such as those seen in Alzheimer’s, Parkinson’s and amyotrophic lateral sclerosis (ALS). As noted in a 2016 study:19

“Administration of quercetin (10 mg/kg body wt/day) reduced aluminum (10 mg/kg body wt/day)-induced oxidative stress (decreased ROS production, increased mitochondrial superoxide dismutase (MnSOD) activity).

In addition, quercetin also prevents aluminum-induced translocation of cyt-c, and up-regulates Bcl-2, down-regulates Bax, p53, caspase-3 activation and reduces DNA fragmentation …

Further electron microscopic studies revealed that quercetin attenuates aluminum-induced mitochondrial swelling, loss of cristae and chromatin condensation. These results indicate that treatment with quercetin may represent a therapeutic strategy to attenuate the neuronal death against aluminum-induced neurodegeneration.”

Quercetin Improves Metabolic Syndrome Traits

Among the most recent papers on this powerful antioxidant is a review20 published in the March 2019 issue of Phytotherapy Research, which looked at nine randomized controlled trials investigating quercetin’s effect on metabolic syndrome.

Metabolic syndrome refers to a cluster of conditions (including high blood pressure, high blood sugar, high triglyceride levels and fat accumulation around the waist) that raise your risk for Type 2 diabetes, heart disease and stroke.

While pooled findings found no effect on fasting plasma glucose, insulin resistance or hemoglobin A1c levels, further subgroup analyses revealed quercetin supplementation “significantly reduced” fasting plasma glucose in studies lasting at least eight weeks and in which dosages of at least 500 milligrams (mg) per day were used.

In studies that included people over the age of 45, “significant” reductions in insulin were also found when using a dosage of 500 mg per day or more. An earlier study,21 published in 2011, looked at quercetin’s effects on certain traits of metabolic syndrome.

This study focused specifically atherosclerosis and inflammation in men with the APOE genotype 3/3, 3/4 and 4/4, and found quercetin significantly decreased waist circumference, postprandial systolic blood pressure, postprandial triacylglycerol, and increased HDL-cholesterol compared to placebo. Here, participants were given 150 mg of quercetin per day for eight weeks.

Research22 on obese rats published in 2008 also found that quercetin supplementation at doses of 2 mg per kilo or 10 mg/kg of body weight for 10 weeks improved systolic blood pressure, triglyceride, total cholesterol and free fatty acid levels. The 10 mg/kg dose also improved the animals’ inflammation status. As noted by the authors:

“In conclusion, both doses of quercetin improved dyslipidemia, hypertension, and hyperinsulinemia in obese Zucker rats, but only the high dose produced antiinflammatory effects in VAT together with a reduction in body weight gain.”

One of the first studies23 to demonstrate quercetin’s beneficial effects on blood pressure was published in 2007. As reported by the authors:

“Epidemiological studies report that quercetin … is associated with reduced risk of coronary heart disease and stroke … Men and women with prehypertension and stage 1 hypertension were enrolled in a randomized, double-blind, placebo-controlled, crossover study to test the efficacy of 730 mg quercetin/d for 28 d[ays] vs. placebo.

Blood pressure at enrollment was … 148 +/- 2/96 +/- 1 in stage 1 hypertensive subjects … Reductions in systolic (-7 +/- 2 mm Hg), diastolic (-5 +/- 2 mm Hg), and mean arterial pressures (-5 +/- 2 mm Hg) were observed in stage 1 hypertensive patients after quercetin treatment … These data are the first to our knowledge to show that quercetin supplementation reduces blood pressure in hypertensive subjects.”

Similarly, a January 2020 systematic review24 of 17 studies concluded quercetin “significantly decreased” blood pressure in human subjects. Those who took it for eight weeks or more also had “significantly” improved high-density lipoprotein cholesterol and triglycerides.

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Quercetin Improves Diabetes-Induced NAFLD

Other recent research25 published in the August 2019 issue of Phytotherapy Research concluded quercetin has a beneficial impact on NAFLD “by ameliorating inflammation, oxidative stress and lipid metabolism.”

Diabetes can play a role in NAFLD as well, showing just how influential insulin resistance is in the development of chronic diseases of all kinds. As explained in the abstract:

“Multiphase pathological processes involve in Type 2 diabetes (T2DM)‐induced nonalcoholic fatty liver disease (NAFLD). However, the therapies are quite limited. In the present study, the hepatoprotective effects and underlying mechanisms of quercetin in T2DM‐induced NAFLD were investigated …

The results revealed that quercetin alleviated serum transaminase levels and markedly reduced T2DM‐induced histological alterations of livers. Additionally, quercetin restored superoxide dismutase, catalase, and glutathione content in livers.

Not only that, quercetin markedly attenuated T2DM‐induced production of interleukin 1 beta, interleukin 6, and TNF‐α. Accompanied by the restoration of the increased serum total bile acid and the decreased liver total bile acid, quercetin could reduce lipid accumulation in the liver … These findings suggested that quercetin might be a potentially effective drug for the treatment of T2DM‐induced NAFLD.”

Quercetin Helps Modulate Gene Expression

According to research26 published in 2016, quercetin even has the ability to trigger tumor regression by interacting with your DNA and activating the mitochondrial pathway of apoptosis (the programmed cell death of damaged cells).

Quercetin was found to induce cytotoxicity in leukemic cells, and the effect was dose-dependent. Limited cytotoxic effects were also found in breast cancer cells. Overall, quercetin increased the life span in cancer-ridden mice fivefold compared to untreated controls.

The authors attributed these effects to quercetin’s direct interaction with DNA and its activation of the mitochondrial pathway of apoptosis, and suggested quercetin’s potential use as a cancer therapy adjunct deserves further exploration.

More recent research27 in the journal Molecules also highlights quercetin’s epigenetic influence and ability to:

  • Interact with cell-signaling pathways
  • Modulate gene expression
  • Influence the activity of transcription factors
  • Modulate microRNAs

MicroRNAs used to be considered “junk” DNA. Far from being useless, research has now revealed that “junk” DNA is actually microRNA and plays a crucial role in regulating genes that make the proteins that build your body.

The microRNA function as “on/off” switches for the genes. Depending on the microRNA input, a single gene can code for any of more than 200 protein products. Quercetin’s ability to module microRNA may also help explain its cytotoxic effects, and why it appears to improve cancer survival (at least in mice).

Quercetin Is a Powerful Antiviral

As mentioned, one of the most well-studied attributes of quercetin is its antiviral capacity, which have been attributed to three main mechanisms of action:

  1. Inhibiting the virus’ ability to infect cells
  2. Inhibiting replication of already infected cells
  3. Reducing infected cells’ resistance to treatment with antiviral medication

For example, research28 funded by the U.S. Department of Defense, published in 2007, found it lowers your risk of viral illness and boosts mental performance following extreme physical stress, which might otherwise undermine your immune function and render you more susceptible to infections.

Here, cyclists who received a daily dose of 1,000 mg of quercetin in combination with vitamin C (which enhances plasma quercetin levels29,30) and niacin (to improve absorption) for five weeks were significantly less likely to contract a viral illness after bicycling three hours a day for three consecutive days, compared to untreated controls. While 45% of the placebo group got sick, only 5% of the treatment group did.

In another study31 funded by the U.S. Defense Advanced Research Projects Agency (DARPA), published in 2008, animals treated with quercetin were challenged with a highly pathogenic H1N1 influenza virus. Again, the treatment group had significantly lower morbidity and mortality than the placebo group. A number of other studies have also confirmed quercetin’s effectiveness against a variety of viruses, including the following:

A 1985 study found quercetin inhibits infectivity and replication of herpes simplex virus type 1, polio-virus type 1, parainfluenza virus type 3 and respiratory syncytial virus.32
A 2010 animal study found that quercetin inhibits both influenza A and B viruses. Two other important discoveries were made. Firstly, the viruses were unable to develop resistance to quercetin, and secondly, when used concomitant with antiviral drugs (amantadine or oseltamivir), the effect was significantly amplified — and it prevented drug-resistance from developing.33
A 2004 animal study investigating quercetin’s effect on influenza used a strain of the H3N2 virus. According to the authors:34

“During influenza virus infection, there is ‘oxidative stress.’ Because quercetin restored the concentrations of many antioxidants, it is proposed that it may be useful as a drug in protecting the lung from the deleterious effects of oxygen derived free radicals released during influenza virus infection.”

Another 2016 study found quercetin offered protection against influenza A virus H1N1 by modulating protein expression. More specifically, the regulation of heat shock proteins, fibronectin 1 and prohibitin was instrumental in reducing viral replication.35
A third study published in 2016 found quercetin inhibited a wide spectrum of influenza strains, including H1N1, H3N2 and H5N1. According to the authors, “This study indicates that quercetin showing inhibitory activity in the early stage of influenza infection provides a future therapeutic option to develop effective, safe and affordable natural products for the treatment and prophylaxis of [influenza A viruses] infections.”36
In 2014, researchers noted that quercetin appears to be “a promising treatment for the common cold,” caused by the rhinovirus, adding that “Quercetin has been shown to reduce viral internalization and replication in vitro, and viral load, lung inflammation and airways hyper-responsiveness in vivo.”37

By attenuating oxidative damage, it also lowers your risk of secondary bacterial infections, which is actually the primary cause of influenza-related deaths. Importantly, quercetin increases mitochondrial biogenesis in skeletal muscle, which suggests part of its antiviral effects are due to enhanced mitochondrial antiviral signaling.

A 2016 animal study38 found quercetin inhibited mouse dengue virus and hepatitis virus. Other studies have confirmed quercetin’s power to inhibit both hepatitis B39 and C40 infection.
Most recently, a March 2020 study41 in the Microbial Pathogenesis journal found quercetin “provides comprehensive protection against Streptococcus pneumoniae infection,” both in vitro and in vivo, primarily by neutralizing pneumolysin (PLY),42 one of the toxins released from pneumococci that encourages S. pneumoniae infection to blossom in the first place. As reported by the authors in Microbial Pathogenesis:

“The results indicated that quercetin significantly reduced PLY-induced hemolytic activity and cytotoxicity via repressing the formation of oligomers.

In addition, treatment with quercetin can reduce PLY-mediated cell injury, improve the survival rate of mice infected with a lethal dose of S. pneumoniae, alleviate the pathological damage of lung tissue and inhibit the release of cytokines (IL-1β and TNF-α) in bronchoalveolar lavage fluid.

Considering the importance of these events in antimicrobial resistant S. pneumoniae pathogenesis, our results indicated that quercetin may be a novel potential drug candidate for the treatment of clinical pneumococcal infections.”

Quercetin Combats Inflammation and Boosts Immunity

Aside from its antiviral activity, quercetin is also known for boosting immunity and combating inflammation. As noted in a 2016 study43 in the journal Nutrients, mechanisms of action include (but is not limited to) the inhibition of:44

Lipopolysaccharide (LPS)-induced tumor necrosis factor α (TNF-α) production in macrophages. TNF-α is a cytokine involved in systemic inflammation, secreted by activated macrophages, a type of immune cell that digests foreign substances, microbes and other harmful or damaged components

LPS-induced mRNA levels of TNF-α and interleukin (IL)-1α in glial cells, which results in “diminished apoptotic neuronal cell death”

The production of inflammation-producing enzymes

Calcium influx into the cell, which in turn inhibits:

Pro-inflammatory cytokine release

Histamine and serotonin release from intestinal mast cells release45

According to this paper, quercetin also stabilizes mast cells, has cytoprotective activity in the gastrointestinal tract, and “a direct regulatory effect on basic functional properties of immune cells,” which allows it to inhibit “a huge panoply of molecular targets in the micromolar concentration range, either by down-regulating or suppressing many inflammatory pathways and functions.”46

Quercetin May Be a Useful Supplement for Many

Considering its wide-ranging benefits, quercetin may be a useful supplement for many, either acutely or more long-term. It’s one of the supplements I recommend keeping in your medicine chest for times when you feel you’re “coming down” with something, be it the common cold or influenza.

If you’re prone to colds and flu, you could consider taking it for a couple of months before cold and flu season hits to boost your immune system. More long-term, it appears useful for those with metabolic syndrome, although it would be foolish to rely on any given supplement without also addressing more fundamental strategies such as diet and exercise.

As explained in my 2015 interview with Dr. Robert Lustig, sugar has been shown to be a causative factor in insulin resistance, which is a hallmark of metabolic syndrome and a risk factor for virtually all chronic disease.

If you have one or more of the conditions that make up metabolic syndrome, you’d be wise to limit your total sugar consumption to 15 grams per day. If you’re healthy, and want to stay that way, your daily sugar limit would be around 25 grams. You can learn more about this and related treatment strategies in “Vitamin D Can Significantly Lower Your Risk of Metabolic Syndrome.”

– Sources and References

Coronavirus protection

Written by Brenton Wight, Health Researcher, LeanMachine
Copyright © 1999-2020 Brenton Wight, LeanMachine
This site is non-profit, existing only to help people improve health and immunity
Updated 3rd July 2020

Australia 3rd July 8:07 pm Central time. Most States update their stats by late morning.
8,255 infected – 65 new cases, all in Victoria (all local except 8 from overseas)
104 died  (mostly elderly with other existing medical conditions)
7,319 Recovered 
832 Theoretical Active Cases (Infected less Deaths less Recovered)
458 Actual Active Cases
27 Hospitalised, 7 in ICU, None on ventilator
2,617,860 Tests 

As of 7:30 am today, Australia is the 72nd country on the list sorted by total infections order, and 84th sorted by deaths. The lower on the list, the better we are controlling the virus spread and treating the patients compared to other countries. Australia has been gradually dropping in the list, but this can change at at any time.
More people are recovering daily, but the outbreak in Victoria means that active cases are increasing, 

World infections 3rd July 2020 7:28 am
10,996,703 infected

523,304 died
6,118,470 Recovered

58,098 in Serious or Critical Condition


NOTE:
The infected figure quoted is misleading, as this is the total confirmed from day 1 of the pandemic. We must subtract the recovered figure (and the deaths) to get the active cases number. Given that many people who recovered do not get tested again because of the disappearance of symptoms and the shortage of test kits or facilities, they are not counted as recovered, so the active figure is generally significantly less, but many infected patients with no or few symptoms may not get tested because of the test kit shortage, and they are probably already in isolation anyway, so the active figure may be higher. In some countries with large populations in remote areas and few medical facilities, infections and deaths go untreated and unreported.
Due to the inaccuracy of the testing, is is possible that a large proportion of those tested positive do not actually have the virus. In spite of these large variances, the figures advertised do give some indication of how fast or slow the virus is spreading.

Statistics

The old saying: “There are lies, damn lies, and then there are statistics” is true when attempting to decipher the real truth about Coronavirus numbers. In China, it is reported that numbers were covered up, and true infections and deaths may have been 10 times the number reported. Doctors were told to use other descriptions on death certificates, claiming pneumonia, heart attack, etc instead of Coronavirus as the cause of death.
In the Western world, the media thrives on death. Doctors are urged to blame Coronavirus when there are often several other health conditions that actually caused the death, when a true diagnosis has never been made and only suspected. Why? High death numbers force politicians to supply benefits to health workers, more equipment, etc. Follow the money.
Deaths from heart attack and other serious conditions has dropped off remarkably in recent weeks, because those deaths are now being reported as Coronavirus deaths.

A recent Stanford University study found that in California, many more people than estimated have unknowingly contracted the virus, mostly with no symptoms at all, so the actual death rate is much lower than stated. Read more:
www.leanmachine.net.au/healthblog/stanford-team-finds-evidence-covid-19-mortality-rate-is-as-low-as-2-17-times-lower-than-whos-estimate

Despite the “Death Virus” headlines, the chart here shows Flu killed more people world wide than COVID-19 in the first 3 months of 2020.
However, 2 months on at the end of May 2020, COVID-19 has supposedly killed over 365,000 people world wide. At the same time in Australia, Flu infections and deaths are down by 90% although Australia and other Southern countries are coming into the Winter Flu season where flu death numbers will ramp up again. Note that deaths are listed as caused by Coronavirus without autopsies or testing, only by “guessing” without any confirmation. Because people who die nearly always have other conditions, those other conditions or medications may have been the cause or certainly co-contributors to those deaths.
Dr. Anthony Fauci says COVID-19 may be no more deadly than seasonal Flu. Read more:
https://www.leanmachine.net.au/healthblog/breaking-news-data-suggests-covid-19-is-not-significantly-different-in-terms-of-deadliness-than-seasonal-flu

Should I get the APP?

There are more than privacy concerns with “The App”. Read more about how the USA are promoting the App and the dangers in using it:
www.leanmachine.net.au/healthblog/contact-tracing-apps-violate-privacy

Australian Death Rate

The Australian death rate is less than 1.5% of infected people, compared with 6% world-wide, so Australia is doing well so far in comparison, but if the infection ramps up exponentially, there may be not enough hospitals, ventilators, other equipment and medical staff to treat very sick patients, and doctors will have to make decisions who gets the resources, which means who lives and who dies.
Note: Ventilators are extensively used in hospitals. In the USA, hospitals are paid tens of thousands of dollars by the Government for every patient who is put on a ventilator, so many receive ventilator treatment even when the requirement is in doubt, but they may be causing more harm than benefits. Read more about problems with ventilators:
www.leanmachine.net.au/healthblog/ventilators-may-increase-risk-of-death-from-covid-19
www.leanmachine.net.au/healthblog/urgent-warning-about-ventilator-use-on-coronavirus-patients-new-research-study

We have achieved minimal infections due to the isolating and social distancing directives.
Infections are already reducing, but to contain the virus, new cases must stop for 2 weeks, with every infected person fully recovered.

Deaths in Perspective

The media loves headlines about the COVID-19 death toll, but fail to mention:
Every day, over 150,000 people die world-wide, but over 200,000 are born, so the world population will double every 35 years.
From 1st January to 30th May 2020, the average death rate from Coronavirus is about 2,000 per day world-wide, and in Australia, less than 1 death per day, which is almost insignificant in the daily deaths from all other causes.
– Every day, 48 Australians die from heart disease, and every year hundreds of Australians die from being overweight or obese. Why are there no laws about fizzy drinks and fries?
– Every day, over 50 Australians die from smoking. Why is it still legal to smoke, and why is tobacco not outlawed?
– Every day, the flu kills 10 Australians, with the rate climbing in spite of record flu jabs administered.
– Every day, breast cancer kills over 8 Australian women.
– Every day, asthma kills at least one Australian.
– Every day, motor accidents kill 3 Australians, and over 60 are injured or disabled.
– Australian bushfires killed 33 Australians in the last year.

Effect of Warmer Climate on Deaths

Why is it that the Australian States with the warmest climate have the lowest Coronavirus death rate?
Statistics at 30th April 2020:

Warm States are:
Northern Territory: 28 cases, 0 deaths (0% death rate)
South Australia: 438 cases, 4 deaths (0.9% death rate, most imported from cruise ships)
Western Australia: 551 cases, 8 deaths (1.5% death rate, most imported from cruise ships)
Queensland: 1034 cases, 6 deaths (0.6% death rate)
Cooler States are:
New South Wales: 3018 cases, 40 deaths (1.33% death rate)
Victoria: 1354 cases, 18 deaths (1.33% death rate)
Tasmania: 219 cases, 12 deaths (5.5% death rate)
Death rates in cooler climates are always higher, because:
1. The body’s immune system does not work as well at cooler temperatures
2. People spend more time indoors, have lower Vitamin D, less fresh air, and poor circulation.

Social Distancing

Social Distancing may actually worsen epidemic outcomes in the long term, as isolation causes reduced immunity, mental problems, fear of unemployment and uncertain financial future and more. Read a detailed explanation:
https://www.leanmachine.net.au/healthblog/social-distancing-may-worsen-epidemic-outcomes/

Chinese Death Rate

Males have been dying at a greater incidence than females, according to a study of 55,000 deaths. It is not a hormonal difference, it is the fact that smoking is much more evident in the male population. If we smoke we die. Of course, everyone dies sooner or later, but smokers die sooner, if not from the Coronavirus, then lung cancer, pneumonia or something else.
Deaths from Coronavirus generally only occur when there are other health factors involved. In order of death rate:

  • Cardiovascular disease (statin and blood pressure medication)
  • Diabetes (obesity, statin and blood pressure medication)
  • Chronic respiratory disease (a result of low Vitamin D3 caused by statins)
  • Hypertension (blood pressure medication)
  • Cancer (immune-depressing drugs)
  • Others including other medications that reduce immunity

What is Coronavirus?

Coronaviruses are a family of viruses containing over a hundred different strains, seven of which cause the common cold. Some of these viruses exist naturally within the human virome, and never express themselves pathogenically, but will potentially cause false positives through the many different COVID-19 testing methods.
Read more about the Virome:
www.leanmachine.net.au/healthblog/profound-implications-of-the-virome-for-human-health-and-autoimmunity

This group of viruses have been around for a long time, first discovered in 1937 in bird populations. In the 1960’s found in humans and normally responsible for the common cold. They can be zoonotic (transferred back and forth between animals and humans) and cause diseases in mammals and birds. Sometimes these viruses mutate, often coming from bats, snakes, pigs (swine flu) or other animals. Other mutated versions of Coronavirus have been SARS and MERS.
The SARS virus is well-documented as a weaponised version of Coronavirus, built by the Chinese Virus Laboratory in Wuhan and caused the previous SARS Epidemic. Read more:
www.leanmachine.net.au/healthblog/sars-cov-2-a-biological-warfare-weapon
This virus, originating in Wuhan, China, now named SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), causes a disease, originally code-named Novel Coronavirus 2019 (nCoV-2019) but then re-named to COVID-19 that spreads more rapidly than SARS, MERS and Flu viruses, but causes death only in those whose immune system is compromised, mainly in those over 50 years old, mainly in the 80+ range, or those subject to air pollution (e.g. in Wuhang, the industrial area of China where air pollution is extreme) because COVID-19 affects the lungs.

COVID-19 is comparatively rare in the very young, partly because of less exposure years to pollution, and partly because the young generally have better immunity.
Viruses are very small, typically between 0.004 to 0.1 microns in size. The Coronavirus is about 0.125 microns, which is fairly large for a virus. The electron microscope image above shows the red “spikes” around the virome, giving a corona,  which gives this virus it’s name.

In humans, COVID-19 causes respiratory infections which are typically mild, and the average person has little to worry about, as most symptoms vary from nothing at all, to a mild condition similar to a common cold. The common cold is a viral infection of the upper respiratory tract. Over 200 viral types are associated with colds, including Rhinovirus (a type of picornavirus with 99 known serotypes), Human Coronavirus, Influenza viruses, Adenoviruses, human respiratory syncytial virus (Orthopneumovirus), Enteroviruses other than Rhinoviruses, human Parainfluenza viruses, and human Metapneumovirus.

Past outbreaks of SARS, originating in China from Avian Flu (Bird Flu), another Coronavirus, and MERS, originating in the Middle East that sporadically jumps from camels to humans, spread to many other countries around the world and still cause problems in some areas, but the media is quiet about these as they are “old news”.
Coronavirus appears to be more easily spread than SARS or MERS, but death from Coronavirus is still significantly less than SARS or MERS. The “RS” in SARS and MERS refers to “Respiratory Syndrome” and deaths are caused by pneumonia-like infection of the lungs. Even the flu causes more deaths than the Coronavirus, but the media is quiet about this, as they want “fear headlines”. The Flu killed 40,000 Americans over their 2019-2020 Flu season, double the number of Coronavirus deaths world-wide at the time. With the population of the USA at just 4% of the world, this makes the Flu 50 times more lethal than the Coronavirus, but the media is full of “Deadly Coronavirus” news.

Update 15th March: One report from National Science Review suggests that there are now 2 types of COVID-19.
Type L, the early version that is transmitted quickly, and the more recent type S which is not as contagious. This report is discredited by University of Glasgow Centre for Virus Research so at this time there are more questions than answers about Coronavirus.

Symptoms

Many infected people who have a healthy immune system are Asymptomatic (have no symptoms) or have very mild symptoms.
These people have been blamed for infecting others, but according to a WHO statement in June, it is extremely rare for an Asymptomatic person to spread COVID-19 to another person.
But people with a poor immune system will have symptoms, and are the main way the virus spreads, especially if they have been active in the community (before isolation or quarantine applied).
Symptoms vary, but these are some to look out for:

  • Fever
  • Sore Throat
  • Dry Cough
  • Muscle pain
  • Shortness of breath
  • Pneumonia-like illness
  • Loss of taste or smell
  • Blood thickening (increasing risk of blood clots)

Anyone with any of these symptoms should report to their doctor or hospital or any of the helplines set up in many areas.
Do NOT report physically, use the telephone and only report physically if instructed to do so.

Man-Made Coronavirus?

A study by Greek scientists, published 27th January 2020, examined the genetic relationships of COVID-2019 and found:
“the new coronavirus provides a new lineage for almost half of its genome, with no close genetic relationships to other viruses within the subgenus of sarbecovirus,” and has an unusual middle segment never seen before in any Coronavirus concluding that it could not have “jumped” from a bat or other animal to humans. Reports indicate that there are sections of the AIDS/HIV virus and the Influenza virus contained in COVID-19, confirmed by the fact that doctors in China, France and now Australia have been using AIDS medications to treat Coronavirus.
The Chinese have tested every animal, dead or alive in the Wuhan Seafood Market and every test came back negative for Coronavirus, and not bats, dead or alive, had been sold or used in any way in the market.
Chinese doctors worked back among patients to find the very first person suffering from Coronavirus, treated in hospital on 1st December 2019, and found that this man had NEVER been to the Wuhan Seafood Market! In fact, out of the first 41 cases, 13 had NEVER been to the market.

This means that we are dealing with a brand new type of “man-made” Coronavirus. The scientists rejected the original hypothesis that the virus originated from random natural mutations between different Coronaviruses.
Read the documentary on the source of the virus:
www.leanmachine.net.au/healthblog/documentary-tracking-down-the-origin-of-the-wuhan-virus
Read why the Wuhan laboratory was shut down in October 2019:
www.leanmachine.net.au/healthblog/why-was-wuhan-lab-locked-down-when-outbreak-began

Also read this article on how Harvard University was involved in modifying Coronavirus AND the Spanish Flu viruses to make them more dangerous:
www.leanmachine.net.au/healthblog/sars-cov-2-a-biological-warfare-weapon

Also read article on PROOF of man-made viruses in Wuhan lab:
www.leanmachine.net.au/healthblog/did-u-s-and-chinese-researchers-collaborate-to-create-a-coronavirus-that-can-infect-humans-shocking-2015-scientific-paper-says-yes
Who is responsible for the COVID-19 virus? Read more:
https://www.leanmachine.net.au/healthblog/the-perps-behind-covid-19
“Smoking Gun” evidence of man-made virus:
www.leanmachine.net.au/healthblog/the-smoking-gun-proving-sars-cov-2-is-an-engineered-virus
Also read this article about how the US and China may have colluded in developing Coronavirus:
www.leanmachine.net.au/healthblog/covid-19-a-leaked-virus-jointly-created-by-us-and-china
Read how the Coronavirus was engineered:
www.leanmachine.net.au/healthblog/undetectable-engineering-methods-used-to-create-sars-cov-2

Coincidence: Research on a Coronavirus vaccine started 5 years ago, funded by Bill and Melinda Gates?
Coincidence: The Bill and Melinda Gates Foundation forecast a Coronavirus pandemic before the pandemic existed.
Coincidence: The Bill and Melinda Gates Foundation co-hosted a pandemic exercise in late 2019 that simulated a global Coronavirus outbreak.
Coincidence: The Bill and Melinda Gates Foundation also fund the group who owns the patent to the deadly virus and were working on a vaccine to solve the predicted crisis.

Coincidence: There is a BSL-4 Virus Research Laboratory at  the Wuhan Institute of Virology (10 miles from the Wuhan Seafood market) – one of only a handful of sites in the world sanctioned by WHO (World Health Organisation) that is certified to work with Ebola virus, small pox, Coronavirus and Bats, and is linked to China’s biological weapons program, which in the past has developed modified Influenza viruses as part of it’s Chemical Warfare program. The Chinese have been developing deadly Coronaviruses for a long time, which may possibly relate to the outbreaks of Avian (“Bird”) Flu, Swine Flu, etc. The USA was also conducting virus research about the same time, until all research of this nature was deemed to be too dangerous, and was prohibited in the USA, but of course, not in China.
News from a BBC investigation 22nd April: The USA has been funding the Wuhan laboratory for years to the tune of about $3.7 million! Read more about this report:
www.leanmachine.net.au/healthblog/shocking-coronavirus-update-u-s-government-funded-virus-research-inside-china-with-a-3-7-million-grant

Read more about bio-weapons and Coronavirus at:
www.leanmachine.net.au/healthblog/bioweapons-expert-coronavirus
Read more about the Wuhan Bioweapon Virus Lab:
www.leanmachine.net.au/healthblog/bioweapon-labs-must-be-shut-down-and-scientists-prosecuted

Coincidence: Faucci and Bill Gates predicted this pandemic in 2017. Watch this video of an interview with Bill Gates: Sorry, this video was removed 26th April for “violating YouTube’s Terms of Service” in other words, YouTube, owned by Microsoft, are censoring any information that tells the truth and discredits the big drug companies.

This article may or may not remain on this site because Governments fear that releasing this information may make the World wide idiotic panic even worse, and my Google statistics are dropping rapidly daily as they are censoring this type of information. I believe in truth at any cost, something we rarely get from the “fake news” propagated by the Big Drug Companies we see on television daily.

Fake News

How much information on Coronavirus is “Fake News?”
It seems that if we do not watch the news, we are uninformed, but if we do watch the news, we are misinformed.
Read just one example of the famous Forbes publication reversing completely the result of a scientific study on the origin of Coronavirus:
www.leanmachine.net.au/healthblog/forbes-caught-in-blatant-censoring-act

WHO – World Health Organisation

The WHO receives much of it’s money from drug companies, but in order to keep the cash coming in, the WHO must protect the drug companies. First, by encouraging vaccinations and pharmaceutical drugs, second by attempting to squash any natural therapies that hurt the drug company profits.

News: After five months of claiming the Coronavirus could spread via “asymptomatic carriers,” necessitating the lockdowns, mask policies, social distancing and mandatory vaccines, the WHO declared on 8th June “Spread of COVID-19 through asymptomatic carriers is very rare”.
This means that apart from known cases that should be quarantined, everyone else should go back to normal – no lockdowns, no masks, no social distancing and no vaccinations!
The next day, I believe due to pressure from the big drug companies who fear that this would damage sales of their yet undeveloped vaccines, the WHO backtracked on this statement and changed the wording from “very rare” to “unknown”. All of the science studies relating to these decisions has not been released.  Read the story here:
www.leanmachine.net.au/healthblog/world-health-organization-scrambling-to-save-credibility-recants-admission-that-asymptomatic-spread-of-covid-19-is-very-rare

How does COVID-19 infect the body?

There are about 40 to 50 trillion cells in the human body, plus another 100 trillion or so bacteria and other cells.
Every cell has a cell membrane on the outside, a nucleus containing our DNA, and our mitochondria in between.
The cell membrane is a complex structure. It allows nutrients to enter and feed the cell, it allows waste products to exit the cell, it controls the amount of water in the cell, and it keeps unwanted visitors out, like viruses. For a virus to enter the cell, it requires some weakness in the membrane, which happens when we have poor immunity. When the virus enters the cell, it takes it over and replicates itself. If the virus cannot find a host (one of our cells) it dies, then breaks down, and the body either uses the remains as food, or expels the waste.
Cells with important attributes in the membrane, such as high pH (alkalinity), Zinc, Vitamin C, Vitamin D, Magnesium, Zinc and other Vitamins and minerals, are generally impervious to foreign  invaders.
This is why people with a diet of processed foods, junk foods that are deficient in all of the things we need, are the ones who will suffer most or even die when they get hit with a virus.
COVID-19 infects the blood
Doctors first thought that Coronavirus started attacking the lungs, it is now apparent that it attacks hemoglobin in red blood cells. Hemoglobin molecules contain 2 oxygen molecules and 2 iron molecules, which hemoglobin needs to carry oxygen to every cell in the body.
Research shows that the virus targets hemoglobin, binding to the iron and breaking it loose from the hemoglobin molecule, stopping the hemoglobin from carrying oxygen. When enough hemoglobin is damaged, there is less oxygen carrying capacity, and the patient has respiratory problems. Lung cells become toxic and inflammatory, leading to pneumonia and cytokine storm. Inflammation causes capillaries to break easily and coagulant proteins rush in, forming tiny blood clots and further reducing oxygen absorption, leading to organ damage and critical illness.
Autopsies show tiny clots and dead cells within the capillaries of the lungs, as well as distended blood vessels in every organ in the body, caused by severe inflammation and increasing risk of strokes, blood clots, heart attacks and organ failure.

Obesity, Diabetes and Cardiovascular Disease
Over 20% of Coronavirus patients with severe infection admitted to hospital had diabetes or hyperglycemia (pre-diabetes), a similar number had cardiovascular conditions, and again, most of those were overweight or obese. All of these conditions already cause hemoglobin problems, and they are the most likely to die.

Boosting the immune system will help people recover from COVID-19, but having a healthy immune system will help defeat the virus before it gets a foothold.
Every cell in the body has many receptors, designed to allow entry of certain nutrients. Researchers have now found that the receptor for ACE Inhibitors and ARB’s (common blood pressure drugs) target a cell receptor, and this is the entry point for the Coronavirus. Read more under my heading “Get off some Drugs”. Read more about why COVID-19 affects seniors, mainly those on medications:
www.leanmachine.net.au/healthblog/want-to-defeat-coronavirus-address-diabetes-and-hypertension
Read how hospital-aquired COVID-19 infections account for 1 in 5 infections:
www.leanmachine.net.au/healthblog/20-of-covid-patients-caught-disease-at-hospital

Can I Catch Coronavirus from Food?

This is unlikely, but food hygiene is always important. Read the full story here:
www.leanmachine.net.au/healthblog/can-you-clean-coronavirus-off-your-food

What Causes Coronavirus Deaths?

1. Poor Immune System
Only those people with poor immune systems and other medical conditions are dying. This is common among older people, because their prescribed medication makes it worse, other medical conditions make it worse, and their uptake of Vitamin D is worse, and worse again because most are taking statin drugs. Rarely, a slightly younger person dies, but invariably when their immune system is compromised, their diet is poor, they live in a polluted area, and have other existing medical conditions (along with dangerous medications that often reduce immunity).
So, age does not increase risk.
Lack of immunity increases risk.

This can be prevented by high-dose supplements of Vitamins C and D3, Selenium, Iodine, etc that can bring their immunity up to reasonable levels. Almost all seniors are on statin medication that damages Vitamin D levels, and locking them up in a Nursing Home ensures they will get no Vitamin D from the sun.
Read more about age and risk of Coronavirus:
www.leanmachine.net.au/healthblog/why-covid-19-disproportionately-affects-the-elderly

2. Cytokine Storm
Inflammation can cause a Cytokine Storm, where large numbers of white blood cells are activated and release inflammatory cytokines, in turn activating yet more white blood cells, giving a positive feedback loop, in turn causing a major immune reaction that can be deadly. Cytokine storms are said to be the cause of a majority of deaths in the Spanish Flu, Swine Flu, Epstein–Barr virus, Pneumonia, and especially COVID-19. Cytokine Storms build into Sepsis. Lab results are typically high in C-reactive protein, sedimentation rate and/or IL6 indicate that a storm is mounting. High-dose IV Vitamin C can help stop or limit these storms and the onset of Sepsis. Vitamin D3 has a unique advantage of improving immunity, yet helping to moderate an immune system in overdrive.
Another supplement to use that helps prevent a cytokine storm is Astaxanthin. Read more about Astaxanthin here:
www.leanmachine.net.au/healthblog/astaxanthin-helps-alleviate-cytokine-storm.

3. Diet
Unhealthy diets cause 11 million deaths every year, more than tobacco and high blood pressure deaths combined. Bad diets reduce immunity, making people more susceptible to all disease including Coronavirus, cancer, cardiovascular, Alzheimer’s, etc.
Always eat fresh, organic food, preferable grown locally, to add decades of healthy living.
Read more about the dangers of processed food:
www.leanmachine.net.au/healthblog/ultraprocessed-food-makes-you-vulnerable-to-covid-19

4. Toxins
Modern processed food is full of pesticides, herbicides, fungicides, hormones, additives and often radioactive particles. In China, there are no restrictions or monitoring of toxins in agriculture, so any food products originating in China are not recommended to be consumed.

The moral of this story:
If we eat junk food, ignore a healthy lifestyle, ignore health supplements, suffer chronic stress, we will DIE, if not from the virus, then from the Flu (just as deadly), cardiovascular disease, diabetes, cancer, Alzheimer’s or any other “modern” diseases that almost never existed a hundred years ago.
If we expect a miracle vaccination to cure the virus from the Big Drug Companies, that is a myth, and most people DIE by that myth.

The 5G Connection

Coincidence: Recently 130,000 5G antennas were installed in Wuhan city, also large 5G installations were installed in Iran and in Northern Italy, and these are the three places where Coronavirus has spread fastest and caused the most deaths. The cruise ship Diamond Princess that held passengers in their cabins for weeks because of a Coronavirus outbreak was also recently fitted with a 5G installation ship-wide. Of course, this is not proof, but it is well-known that the extremely high frequency radiation from 5G (10 times the power and up to 26 times the frequency) damages DNA and reduces immunity, and although 5G has some technical benefits, the cost to the human race is high. Scientific studies on 5G prove the danger, but telecommunications companies ignore the risk and continue the 5G rollout which is a multi-trillion dollar business.
4G wavelengths travel along the surface of the skin, but 5G penetrates deep into the body at pulsed frequencies up to 90 GHz, disrupting cell membranes and damaging our DNA.
Read more about 5G :
www.leanmachine.net.au/healthblog/siim-land-interviews-dr-mercola-about-emfd
And more about the dangers:
www.leanmachine.net.au/healthblog/5g-the-global-human-experiment-without-consent-most-censored-topic-of-our-time

Coronavirus Vaccination?

Doctors are only looking for a new vaccine, overlooking proven natural therapies that build immunity to all disease!
Vaccines can save people, but also kill people. The reported average is one death per 1 million people injected with any vaccine, however most go unreported because the deaths are normally reported as:

  • Some organ failure (caused by the vaccine)
  • Some variation of a disease that was caused by the vaccine
  • The vaccine caused reduced immunity

So if every person in the world was vaccinated (an impossibility) then using reported statistics, at least 7,000 people would be reportedly killed by the vaccine, and probably at least 10 times that number.
So health officials must weigh up how many can be saved by a vaccine versus how many would be killed or harmed by the vaccine.
Even Bill Gates, in a rare interview, admitted that the current flu vaccine does not work well in seniors, and that any new Coronavirus vaccine would probably harm 700,000 people! Read here:
www.leanmachine.net.au/healthblog/bill-gates-admits-700000-people-will-be-harmed-or-killed-by-his-covid-19-solution
Unfortunately, doctors ignore the natural therapies which are proven to destroy viruses and without the dangerous side-effects of vaccines and prescription medication.

Why are the big drug companies intent on discrediting all of the natural therapies and concentrating on vaccinations?
Because they make a fortune on vaccinations, and are protected from law suits when the vaccination fails, harms or kills someone!

After China’s 2002 SARS-CoV outbreak, teams of US & foreign scientists first attempted to develop Coronavirus vaccines. They vaccinated animals with the four most promising vaccines, which seemed successful as all the animals developed a strong antibody response to Coronavirus. But when they exposed the vaccinated animals to the wild virus, the results were horrifying. Vaccinated animals suffered hyper-immune responses including inflammation throughout their bodies, especially in their lungs. This same “enhanced immune response” was discovered during human testing of the failed RSV vaccine tests in the 1960s when two children died from the vaccine.
Read more about how difficult or impossible it is to produce a Coronavirus vaccination:
www.leanmachine.net.au/healthblog/the-well-known-hazards-of-coronavirus-vaccines
Read how how the Gates/Oxford vaccine is making monkeys sick, but the truth is hidden and the trial is going ahead on humans:
www.leanmachine.net.au/healthblog/another-gates-vaccine-bites-the-dust-sick-monkeys-everywhere

Read more about the dangers of rushing a vaccine to market:
www.leanmachine.net.au/healthblog/coronavirus-vaccine-being-rushed-to-market-by-skipping-usual-animal-testing
Read more in my vaccination article:
www.leanmachine.net.au/healthblog/do-we-need-vaccinations/
Want more info on vaccinations? Go here:
www.leanmachine.net.au/healthblog/vaccinated-vs-unvaccinated-part-9
Read more again about rushing a vaccine:
https://www.leanmachine.net.au/healthblog/fast-tracked-covid-19-vaccine-what-could-go-wrong

Moderna claims vaccine trial is “promising” with a 20% serious condition rate:
www.leanmachine.net.au/healthblog/vaccine-trial-catastrophe-moderna-vaccine-has-20-serious-injury-rate-in-high-dose-group
Read about why the Governments continue the false narrative that the Coronavirus jumped from animals to humans in the Wuhan Seafood Market:
www.leanmachine.net.au/healthblog/why-is-protecting-covid-19-origin-narrative-so-important
Read about the crimes committed against humans by Big Pharma and Bill Gates:
www.leanmachine.net.au/healthblog/crimes-against-humanity-italian-member-of-parliament-demands-arrest-of-bill-gates
Read how the CDC lied about the dangers of vaccines, causing 1 in 16 boys in Ireland to have Autism:
www.leanmachine.net.au/healthblog/one-in-every-16-irish-boys-has-autism-crisis-worse-than-covid-19-and-nobody-cares
Unexpected drop in infant deaths in lockdown
Because the lockdowns prevented many parents from taking their infants for scheduled vaccinations, less infants died!
In fact, death rates dropped by over 36% in infants and children, at the same time as death rates in seniors were increasing due to Coronavirus. Read more in this comprehensive article:
www.leanmachine.net.au/healthblog/lessons-from-the-lockdown-why-are-so-many-fewer-children-dying/

Coronavirus Cure?

Using old technology in a new way for a better, faster cure than any vaccination:
www.leanmachine.net.au/healthblog/did-this-scientist-develop-a-cure-for-covid-19

Coronavirus Test Kits

Most testing is carried out using various PCR (polymerase chain reaction), or rRT-PCR (real-time reverse transcription polymerase chain reaction) tests, using nasal and throat swabs, and is unreliable after the first week of infection, where it may disappear in the throat but continues to multiply in the lungs.
PCR tests were developed at Berlin in January 2020,  in the United Kingdom, in South Korea, in China and the United States. Older versions of the test kits caused inconclusive results due to faulty reagents, and were not reliable until 28 February 2020, and it was not until then that state and local laboratories were permitted to begin testing.
There are many false positives, and the CDC (Centers for Disease Control) admit that the test kits do not always work properly. The USA supplies test kits for many parts of the world, but Australia has their own, developed in South Australia by SA Pathology, which give results much faster. Accuracy remains to be seen, but appears to be more successful than tests from other countries.
Read more about the evolution of the test process:
www.leanmachine.net.au/healthblog/was-the-covid-19-test-meant-to-detect-a-virus
And more recent testing information:
www.leanmachine.net.au/healthblog/are-public-health-decisions-based-on-inaccurate-covid-tests

Because there are so many different strains of the Coronavirus, including about 7 strains responsible for the Common Cold, testing often reveals an “indeterminate result” but the testing technician must give only a positive or negative result and nothing in-between, so to be on the “safe side” all indeterminate tests are classified as positive for COVID-19, so many of these results are a false positive.
In addition, humans have a natural virome (billions of friendly and helpful viruses)  that often contain Coronaviruses, that sit happily in the body doing no harm, but the tests can give a false positive again when encountering this virus.

Pregnant Women

A small Chinese study of 6 mothers who were positive for COVID-19 and who had cesarean deliveries, all had babies free from the virus, but had high levels of antibodies IgG and IgM (Imminoglobulins G and M), indicating that antibodies to the virus were present. Normally IgG passes across the placenta, but IgM does not due the the larger molecule size, but the babies acquired IgM in some way. Later testing found the babies did not develop the virus.

Medical Treatment

Standard treatment in Western countries is not always correct, sometimes completely wrong and ineffective.
Anti-viral medications have had some degree of success, but can have significant side-effects.
Many doctors in China, France, Italy, Spain and more recently in the USA, are using drugs “off-label” (i.e. not approved for use for COVID-19) such as chloroquine, hydroxychloroquine, azithromycin, lopinavir-ritonavir, favipiravir, remdesivir, ribavirin, interferon, convalescent plasma, steroids, and anti–IL-6 inhibitors, based on either their in vitro antiviral or anti-inflammatory properties.

The Malaria drugs Hydroxychloroquine brand name Plaquenil, and Chloroquine are generic drugs used to treat lupus, arthritis and malaria, and are claimed relatively safe, with the main side effect being stomach irritation, though they can cause echocardiogram and vision changes (what? heart and eye problems are safe?). Echocardiogram side effects include elongating the QT wave, meaning alteration of electrical activity in the heart, possibly causing seizure, fainting and sudden death.

Chloroquine acts as a zinc ionophore, allowing more zinc into the cells, where it promotes death of the virus.
So it is really the Zinc rather than the drug that kills the virus.

Update: Hydroxychloroquine is ONLY effective in the presence of Zinc. Read more:
www.leanmachine.net.au/healthblog/hydroxychloroquine-needs-zinc-to-be-effective-against-covid-19-infection-doctor-says

Read more about the benefits and dangers of Chloroquine at:
www.leanmachine.net.au/healthblog/antimalarial-medications-a-covid-19-treatment-option.

Hydroxychloroquine has been found useful as a preventive rather than a cure by Chinese doctors, but can moderate symptoms if administered to a sick person.
Australian doctors announced on 21st March that a trial is starting on a combination of an AIDS anti-viral drug Kaletra (a mixture of anti-HIV medications) combined with Hydroxychloroquine. This combination has had better success in-vitro when combined, much better than each individually, but we will see what happens in real people.

French doctors have conducted a successful study with a combination of Hydroxychloroquine and the antibiotic azithromycin (azithromycin is used to prevent bacterial pneumonia). This is surprising, since antibiotics generally reduce immunity, the benefit is probably due to reduced bacterial complications in the lungs that are damaged by the COVID-19 virus.
Fake News on Hydroxychloroquine:
Articles published in the Lancet and on television, even in Australia, claimed that Hydroxychloroquine does not work for COVID-19 and is very dangerous and can kill people, coincidentally just after President Trump said he was using it. Red faces everywhere when the truth was uncovered: This article was a total fabrication (lie) produced not by doctors, but by “spin” people with no medical training, presumably hired to discredit Trump! No retractions that I have seen on Australian TV because no one wants to admit that they lied.

Quercetin is also being studied as a much safer alternative to Chloroquine. Read more:
www.leanmachine.net.au/healthblog/is-quercetin-a-safer-alternative-to-hydroxychloroquine

Another study is under way using Remdesivir, a drug originally intended for treating the Ebola virus.

In Australia, symptoms have been very mild, and patients have recovered with “only the use of Paracetamol” (Acetaminophen in the USA). What did these doctors learn at medical school?
How could they forget the basic rule by the ancient Greek physician Parmenides about 2,500 years ago: “Give me the power to create a fever and I can cure any disease.”

With the world-wide introduction of Aspirin, the Spanish Flu killed up to 50 million people, but most would have survived if they had NOT taken Aspirin, which lowers body temperature. Paracetamol also lowers body temperature, but fever is the basic method by which the body defeats disease, so removing the fever only exacerbates the disease.
Apart from reducing fever, Paracetamol destroys L-Glutathione, the body’s “Master Antioxidant” which is the most important thing we need to defeat disease, and Paracetamol damages the liver (many people on the liver transplant waiting list are there because of Paracetamol overdose).
In Australia, doctors still recommend Paracetamol (Acetaminophen or Tylenol in the USA) for every COVID-19 patient, which increases risk of sickness, liver damage and death!
For a comparison of Coronavirus to the Spanish Flu, read more:
www.leanmachine.net.au/healthblog/how-does-covid-19-compare-to-the-spanish-flu

I think more promising is convalescent plasma treatment, where a sick person is given a transfusion of blood plasma from a patient who has recovered from the virus. This plasma contains antibodies that have already defeated the virus, and side-effects should be near zero in theory.

HBOT (Hyperbaric Oxygen Therapy)

HBOT is a chamber pressurised with a high-oxygen air mixture, and shows promise as a treatment, however most hospitals will not have anywhere near enough. Read more:
www.leanmachine.net.au/healthblog/hyperbaric-oxygen-therapy-for-covid-19

Vitamins C and D are finally being used to treat Coronavirus!

At Last! 7th April 2020: I have been telling people for 10 years about these benefits, while the drug companies dismiss the benefits as “fake claims”, afraid of losing millions of dollars when cheap, readily available Vitamins beat most drugs hands down.
Now doctors in the USA are using these Vitamins, and eventually Australian doctors will get the message too.
Read the full story:
www.leanmachine.net.au/healthblog/vitamins-c-and-d-finally-adopted-as-coronavirus-treatment

The benefits of IV (Intravenous) Vitamin C therapy have been known for a long time, but doctors are strangely reluctant to use it!  The Chinese are now using Vitamin C therapy, but Western doctors are still failing to use the most basic, inexpensive and effective tools available. Vitamin C supplements are effective to prevent or minimise COVID-19 but daily doses of over about 9,000 mg (or up to 20,000 mg in divided doses every 3 to 4 hours) can cause stomach upset, so for treating patients with severe symptoms, 50,000 mg or more should be administered by IV which by-passes the stomach, and has almost zero side-effects.
See the article about New York doctors achieving significant results with Vitamin C at only 1500 mg every 3 or 4 hours given by IV:
www.leanmachine.net.au/healthblog/breaking-news-covid-19-patients-getting-vitamin-c-therapy-in-n-y-hospitals

Ozone therapy has been used for a long time. Read more at:
https://articles.mercola.com/sites/articles/archive/2020/04/05/ozone-therapy.aspx

Coronavirus can increase risk of blood clots, which can be deadly.
Read about the natural treatment that is rarely seen in hospitals:
www.leanmachine.net.au/healthblog/might-enzymes-help-blood-clotting-associated-with-covid-19

I receive the JAMA Network updates daily, which contains the latest medical info that doctors use to treat Coronavirus. No mention of any vitamin or any other alternative health medicine or supplement, and they even say NOT to use Chloroquine or Hydroxychloroquine even though they are effective. No wonder these doctors are watching patients die.

Fraud in WHO and CDC

To say that the WHO and the CDC were fraudulent would be an understatement. Read more in this article:
www.leanmachine.net.au/healthblog/breaking-news-medical-doctor-exposes-fraud-inside-who-cdc-and-led-by-dr-anthony-fauci

Can we get these drugs now?

In theory, yes, Hydroxychloroquine (also Chloroquine) is “off-label” but doctors in the USA can prescribe it. Unfortunately there are not enough supplies, as all available stockpiles are used in studies and treatment of desperately ill people.

Get off some drugs

Do NOT continue taking Statins. Statins (cholesterol drugs) cause the liver to make less cholesterol, but also reduce production of Vitamin D, and Vitamin D is one of the best defenses against all disease, including COVID-19.
Statins are prescribed to the majority of seniors to “protect them from cardiovascular disease” but they actually do the opposite, increasing death rates by all other causes.
Statins also reduce production of Cholesterol Sulfate, and I have another article coming up on this important ingredient for healthy blood flow.
Statins also reduce production of CoQ10 (Co-Enzyme Q10) which is essential for our mitochondria, the energy-packs in each of our cells, especially our heart cells, and we need a strong and healthy heart to deal with any virus.
Statins cause muscle breakdown, sometimes so severe that the kidneys fail as they cannot deal with the waste from the muscle breakdown, resulting in death.
Statins also affect many more of the 48,000 different things that the liver normally manufactures for a healthy body.

Do not take ACE (angiotensin-converting enzyme) Inhibitors or ARB (Angiotensin Receptor Blocker) which are very common blood pressure drugs, even though the JAMA Network advises not to stop these drugs.
These drugs have shown in rodent studies to upregulate ACE2 expression hence may affect the severity of Coronavirus infections, because Coronaviruses now have a much more receptive entry point.
ACE Inhibitors have a common side-effect, much more common than the drug companies admit: A persistent, dry, unproductive cough. Is it a coincidence that a side-effect of COVID-19 is also: A persistent, dry, unproductive cough?. Read more about why COVID-19 affects seniors, especially those on medications:
www.leanmachine.net.au/healthblog/want-to-defeat-coronavirus-address-diabetes-and-hypertension
Note that ibuprofen (Advil) also acts as an ACE Inhibitor.

Natural prevention for Coronavirus

Several years ago, the famous Andrew Saul (the Vitamin Doctor) said “one day, vitamins would be used before drugs when it comes to sickness” and in the current pandemic it is being proven every day, as more and more people die from prescription drugs, and more and more are saved by healthy doses of Vitamins and other natural methods.
All viruses have weaknesses that can be exploited in simple remedies, including some that have been used for hundreds or thousands of years.

Sodium Bicarbonate

Viruses generally thrive in an acidic environment (low pH) but die in an alkaline environment (high pH).
Sodium Bicarbonate (Baking Soda) is not only safer than yeast as a raising agent in baking products, it is the best and fastest way to increase pH (alkalinity) when taken internally, and/or used on the skin.
Dissolve completely half a teaspoon in half a glass of water and drink every 2 hours, or as directed by a physician.
Do not take more than 7 times in 24 hours, 3 times for those over 60.
Add a cup or more to a bath and soak. For skin wounds, mix a little water into Bicarb powder to make a paste and apply to the affected area. To treat Coronavirus (or Cancer or other serious disease) aim for a urine pH level of 8.0 for 10 days, take a week off then repeat for another 7 to 10 days. Repeat the cycle as long as required.
Read more about Baking Soda benefits:
www.leanmachine.net.au/healthblog/woman-believes-soda-saved-her-family-from-the-1918-spanish-flu-pandemic
www.leanmachine.net.au/healthblog/can-this-inexpensive-and-safe-treatment-combat-viral-infections

Vitamin D3

A new study found that people with low levels of Vitamin D3 were much more likely to suffer serious symptoms or death from Coronavirus. Of course, I have been advising the benefits of D3 for 10 years because the scientific evidence is indisputable. Read more on this study:
www.leanmachine.net.au/healthblog/patients-low-in-vitamin-d-twice-as-likely-to-develop-severe-covid-19-symptoms-new-study
And more in this article:
www.leanmachine.net.au/healthblog/vitamin-d-combats-viral-infections-and-boosts-immune-system
And from Dr Mercola:

https://www.leanmachine.net.au/healthblog/the-most-important-paper-dr-mercola-has-ever-written
Vitamin D3 stimulates “innate immunity” to viruses and bacteria, at the same time moderating auto-immune conditions.
Importantly, Vitamin D3 can regulate immune responses and cytokine production to prevent COVID-19 from creating a “cytokine storm” (the main problem with Sepsis) that can destroy the body’s organs, leading to death.

Typical doses available in retail stores are about 1,000 IU and this is enough to stop rickets, but nowhere near enough to build immunity. I have taken 5,000 IU daily for 10 years and have never had a cold or flu in that time. More recently I have taken 10,000 IU 3 days a week. I also get as much sunshine as I can get (without turning pink) in the middle of the day from a clear blue sky to increase D3 and also reap the many other benefits of sunshine such as Cholesterol Sulfate. This is the complete opposite of advice given by the Cancer authorities who say that the sun is our enemy and we must avoid sun, especially in the middle of the day. Why is it then that more office workers die from melanoma than construction workers?
Be wary of lies about Vitamins from the big drug companies who are desperate to sabotage sales of vitamins that are eroding their expensive and dangerous drugs. Read about the lies CNN News tell about life-saving Vitamin D:
www.leanmachine.net.au/healthblog/cnn-spreads-deadly-lies-about-vitamin-d-for-covid-19
Vitamin D3 is a fat-soluble vitamin (actually not a true vitamin, but a Steroid Hormone) so we do not need to take it every day, but should be taken with a meal containing some healthy fat (Coconut oil, Avocado, Olive Oil, etc). Some doctors give Vitamin D3 by IV as a monthly dose of 40,000 IU to 100,000 IU.

D3 Blood Tests:  Doctors say healthy D3 levels mean over 75 nmol/L (30 ng/ml). This level was only 60 nmol/L recently but doctors finally realised that this was still way too low. If D3 test results come in at over this threshold, the doctor will say you are fine.
However, true experts in this field say that truly optimum for a normal healthy person for immunity to disease, is between 125 and 175 nmol/L (50 – 70 ng/ml) and these levels are almost impossible to obtain unless we live outdoors or supplement.
For those recovering from cancer or other serious disease, optimum should be 175 to 250 nmol/L (70 – 100 ng/ml).
NOTE: Because Vitamin D3 increases Calcium absorption, we should always take Vitamin K2 MK7 that helps place Calcium into the bones and teeth where it belongs, and keep it out of the blood where it can form clots. I recommend at least 200mcg of and up to 300mcg Vitamin K2 MK7 in conjunction with 5000 IU Vitamin D3. Note that the MK7 version of Vitamin K2 is twice as beneficial as other versions, and taking high doses over 300mcg daily does no harm, but offers no extra benefits.

As we age, our ability to absorb Vitamin D3 decreases, which is partly why more seniors have worse outcomes with Coronavirus. Generally, over 50’s need 5,000 IU daily, and over 80’s need 8,000 IU daily. Always ask for a D3 test with an annual blood test to ensure your sunshine and/or supplementation is sufficient.
Read more about Vitamin D3 in my article:
www.leanmachine.net.au/healthblog/vitamin-d3
Also read how Vitamin D3 reduces severity and risk of death from Coronavirus:
www.leanmachine.net.au/healthblog/vitamin-d-level-is-directly-correlated-to-covid-19-outcome

African Americans are 3 to 6 times more liable to suffer COVID-19 infections AND to dying from those infections, and also Hispanics to a lesser extent. Doctors look at socio-enomic, housing, crime rates, existing obesity, other health issues  and other factors, but overlook the real reason: Low Vitamin D3 because they do NOT absorb enough D3 from sunlight and should ALWAYS supplement with Vitamin D3.

Vitamin A

Vitamin A increases immunity, and works well in conjunction with Vitamin D3. Both can be toxic when taken at very high doses, but when taken together, the toxic level is doubled, which really means the toxic level of one really means a deficiency of the other.

Vitamin C

Vitamin C powder is a cheap and effective way of improving immunity, also Liposomal Vitamin C that the body retains better. The Orthomolecular Medicine News Service says “The Coronavirus pandemic can be dramatically slowed, or stopped, with the immediate widespread use of high doses of vitamin C. Physicians have demonstrated the powerful antiviral action of vitamin C for decades. There has been a lack of media coverage of this effective and successful approach against viruses in general, and Coronavirus in particular.
Vitamin C is antiviral, antitoxin, antihistamine, anti-inflammatory, works as an antibiotic, even an antidepressant!
High doses of vitamin C, typically over 9,000 mg daily, can upset the stomach, but hospitals should be using the safe high doses given by IV (direct into the blood), often doses from 20,000 mg to 50,000 mg or more, with proven success rates for serious Coronavirus cases.

NEWS Announcement: Chinese Government now recommends Vitamin C for Coronavirus treatment.
Article: www.leanmachine.net.au/healthblog/coronavirus-solution-shanghai-government-recommends-vitamin-c-for-covid-19/

Read more about Vitamin C:
www.leanmachine.net.au/healthblog/dr-richard-cheng-discusses-optimal-daily-vitamin-c-intake
Read more in Rhona Patrick’s article on Vitamin C:
www.leanmachine.net.au/healthblog/rhonda-patrick-on-vitamin-c

Magnesium Chloride Hexahydrate

Magnesium Chloride Hexahydrate Spray is a topical spray, used on the skin where it is absorbed directly into the bloodstream.
Also Magnesium Chloride Hexahydrate Flakes can be used to soak in a bath.
This by-passes the digestive system, which can be a problem for high doses of magnesium taken orally that may cause loose bowel motions.
There are many different magnesium salts available, but Magnesium Chloride Hexahydrate appears to work best for immunity to viral infections, as well as the traditional Magnesium benefits to Heart, Bones and over 280 biochemical reactions in the body. Most magnesium supplements will help, aim for 400mg per day, or use a cup of Epsom Salts in a bath for direct absorption through the skin.

Note that Vitamin C, Vitamin D3 and Magnesium work in a synergistic manner, that is, when combined, work better than each one work alone.

Vitamin B1 (Thiamine)

Vitamin B Complex contains Vitamins B1, B2, B3, B6, B9, B12 which are all important for health.
Read more about Vitamin B1:
www.leanmachine.net.au/healthblog/vitamin-b1-is-vital-to-protect-against-infectious-disease

Zinc

Zinc is essential for the immune system. A 30-mg dosage of zinc in one study showed a significant increase in levels of infection-fighting T cells.
Zinc is used up faster when we have an illness, so supplementation is essential. See more under the Diet heading.
Read more about zinc:
www.leanmachine.net.au/healthblog/how-to-improve-zinc-uptake-to-boost-immune-health

Selenium

Selenium is an antioxidant that lowers oxidative stress in the body, reducing inflammation and improving immunity to viruses, bacteria and parasites.
At the same time, Selenium protects against heart disease, cancer, Alzheimer’s and other “Modern” diseases.

Glutathione

Glutathione is the body’s “Master Antioxidant” but is used up by stress and bad diets.
Glutathione is also clobbered by Paracetamol (Panadol), also called Acetaminophen or Tylenol in the USA despite being advertised as “Safe and Effective”, and impacts liver health and substantially reduces immunity. The worst side-effect is reducing body temperature, when the best way of killing off any virus is to raise body temperature (or allow a natural fever when fighting infection).
Glutathione is not well absorbed, as much is lost in the digestive process, so the above supplement that is dissolved in the mouth gets straight into the blood through the mucous lining of the mouth. It is also the “reduced” form that is already in the beneficial form and does not have to be converted, unlike other non-reduced forms.
An alternative is precursors (building blocks) of Glutathione, NAC (N-Acetyl Cysteine) and Glycine will increase Glutathione levels. NAC is used in hospitals as a treatment for Paracetamol overdose.
Read more about treatment of Coronavirus and Influenza with NAC and Reduced Glutathione:
www.leanmachine.net.au/healthblog/potential-roles-of-nac-and-glutathione-in-covid-19-treatment

Iodine

Iodine has been used for centuries to treat infections and disease.
It is still one of the very few weapons to destroy viruses as well as bacteria, molds, yeasts, protozoa and more.
Iodine increases immunity, but in modern times, people are becoming more deficient in Iodine, because:

  • Chlorine in drinking water displaces iodine in the thyroid, causing thyroid problems
  • People are reducing salt intake, so getting less iodine

Dr. Brownstein from Detroit tested 7,000 patients and found 97% were deficient in Iodine.
Few researchers test for Iodine. If they did and treated those deficient with supplemental Iodine, there would be far fewer diseases in the world, and far fewer outbreaks of mutated viruses.

Lysine

Lysine is a natural amino acid, and studies have demonstrated that Lysine can reduce infection rates of the varicella zoster virus (VZV) Chicken Pox virus, so I recommend everyone take Lysine supplements. Only 1/4 teaspoon daily is cheap insurance for viral infections. Also helps prevent Shingles which is becoming an epidemic because of effects of the Varicella vaccine that reduces immunity to Shingles, which has now reached epidemic proportions, but only in those who have had the Chicken Pox vaccine.

Quercetin

Quercetin has long been a valuable ingredient found in many foods such as Red Onions, Elderberries, Kale, Apples, Spinach, Red Grapes, Raw Black Plums and many more.
Already famous for health in Cancer, Cardiovascular, Kidney and other diseases, studies are now under way for the effect on Coronavirus which is already showing promising results.
See the study on Quercetin for Coronavirus:
www.leanmachine.net.au/healthblog/breaking-news-can-quercetin-help-us-to-avoid-the-threat-of-coronavirus-infection

Quercetin also helps the body cells take in zinc. Read more:
www.leanmachine.net.au/healthblog/is-quercetin-a-safer-alternative-to-hydroxychloroquine

Gut

The gut is responsible for 80% of our immune system, so we must look after our 100 trillion friendly microbes, usually totaling about 2 kg of our body weight.
Of course, taking antibiotics destroys a large proportion of the friendly bacteria, compromising our immune system.
Antibiotics also have no effect on viruses, so antibiotics will only have a negative effect on any virus condition and increase the risk of microbes becoming resistant to antibiotics.
We must also avoid a “leaky gut” where imperfections in the gut lining allow raw food to directly enter the bloodstream, causing allergies.

Hydrogen

Hydrogen gas is a treatment that improves lung function, but not many hospitals have it available or use it.
Because hydrogen is the smallest atom (1 proton, 1 electron) it can go everywhere in the body, nothing can stop it. Hydrogen can cross cell membranes and the blood-brain barrier. It can protect DNA and mitochondria from damage due to free radicals (unstable molecules that tear other molecules apart to gain stability). Read more about Hydrogen and it’s effect on Coronavirus:
www.leanmachine.net.au/healthblog/how-molecular-hydrogen-can-help-against-covid-19

Hydrogen supplements are available. Drop a tablet into a glass of water and drink.

Hydrogen Peroxide

Hydrogen Peroxide has been used for decades to fight viruses. In fact, the body normally makes hydrogen peroxide, but because this is a natural product, the Drug companies are not interested because they cannot patent it or make money from it. Read more in this article:
www.leanmachine.net.au/healthblog/censored-by-the-media-this-at-home-remedy-knocks-out-viruses-safely-and-effectively

Diet

Healthy foods build our immune system. Bad foods bring it down.
Processed foods, sugar, bad fats (margarine, canola oil) and anything with unpronounceable ingredients or numbers on the ingredient list.
Always eat fresh, colorful fruits and vegetables. Buy organic and grass-fed meat when you can, use plant-based foods more than animal products.
Some immune-boosting foods include garlic, onion, leek, ginger, broccoli sprouts, reishi and shiitake mushrooms, green tea, cinnamon, clove, oregano, thyme, bitter melon, stevia.
Citrus, berries of all kinds, broccoli, peppers all have Vitamin C.
Walnuts, almonds and other nuts, seeds, leafy green vegetables, avocados all have Vitamin E.
Walnuts in particular can help maintain the length of telomeres, which maintains health and immunity in seniors. Read more about walnuts: www.leanmachine.net.au/healthblog/eating-walnuts-preserves-youthful-telomere-strands
Seafoods, cashews, almonds, pumpkin seeds, lentils, chickpeas, eggs, grass-fed beef, Cacao or Cocoa, yogurt, kefir, dark chocolate, dairy (especially ricotta cheese), mushrooms, avocados, chicken are some of the best sources of Zinc which is essential for over 300 enzyme reactions in the body. Zinc is used up at a much higher rate if we have an illness, so supplementation should be considered if sick or if we cannot get enough through our diet.
Fish, flaxseed, walnuts have high levels of Omega 3.
Fermented foods, yogurt, kefir are high in Probiotics.

Mitochondrial Function

Dysfunction of our mitochondria, the tiny energy packs inside every cell in the body, is always a problem for our general health and immune function.
Supplements to support mitochondrial function include:

Herbs

Herbs are best known for increasing flavour in cooking, but many herbs have natural ability to fight viruses, bacteria and fungi.
Echinacea has antiviral properties, containing echinacein that inhibits bacteria and viruses from penetrating healthy cells.
Elderberry contains anthocyanidins with antioxidant, anti-inflammatory and immunostimulant properties.
Andrographis has antiviral, antimicrobial, antioxidant and anti-inflammatory properties.
Garlic, especially raw garlic, is well-known for antiviral properties, as well as being used for tuberculosis, pneumonia, thrush, herpes, eye infections, ear infections, cancer, hypertension, cardiovascular health and even hair loss.
Astragalus Extract, has powerful antiviral, antibacterial and anti-inflammatory properties, used to boost the immune system, for HSV (herpes simplex virus), coxsackie B virus, wound care, and is an adaptogen for lowering cortisol.
Olive Leaf Extract has antiviral, antibacterial, antifungal and anti-cancer properties due to the polyphenol ingredient oleuropein, a potent antioxidant that helps in blood pressure and cardiovascular disease.
Pau D’Arco is used for arthritis, pain, inflammation, prostate health, fever, dysentery, boils, ulcers and cancers.

Others are Goldenseal, Japanese honeysuckle, Stinging Nettle.
For more reading on herbs, read:
www.leanmachine.net.au/healthblog/can-herbal-medicines-fight-wuhan-coronavirus

Exercise

If we are confined due to isolation or quarantine directives, staying in bed or watching TV all day is bad for our brains as well as our health and immunity. If we have a back yard, balcony or other ways to get fresh air and sunshine, get outside and get some exercise.
For more reading on exercise benefits:
www.leanmachine.net.au/healthblog/how-exercise-may-reduce-your-risk-of-death-from-covid-19
Read how staying at home can lower Vitamin D levels and increase risk of infection and death from Coronavirus:
www.leanmachine.net.au/healthblog/are-stay-at-home-orders-decimating-vitamin-d-levels

Get Outside

Confining ourselves indoors is detrimental to our immune system. Getting outdoors as much as possible is one way to maintain or improve our immune system. This is proven by Nursing Home procedures that lock people in their rooms, and cruise liners that confine people to their cabins, both situations causing major outbreaks and deaths from the virus. Read more here about the report from two doctors that was banned on YouTube:
www.leanmachine.net.au/healthblog/two-california-doctors-issue-major-warning-about-shelter-in-place-orders

What NOT to do

Do not take NSAIDS (Ibuprofen, Aspirin) or other anti-inflammatory drugs that impact immunity, as the body’s normal response to a pathogen is to increase fever and inflammation.
Normal body temperatures are 36 to 37 degrees C, and normally varies. Body temperature will usually be at its lowest just before dawn and highest in the afternoon, and will be higher after exercise. If fever goes over 40 degrees C (104 degrees Fahrenheit) in a child or adult, it can become dangerous, and may cause seizures at 106 degrees F, and potentially deadly at 108 degrees F. It can be reduced naturally by sitting in a bath of cool to lukewarm water and sponging the water over the body, and no side-effects! Note that infants have much less tolerance to fevers. See a doctor immediately.
Do NOT get a flu shot. The diet and supplements above will help with Coronavirus, the Flu, Colds and almost everything else. A study on the Coronavirus deaths in Italy show a 36% INCREASE in Coronavirus infections in those who have had the Flu shot. The Flu shot is known to be only slightly effective in preventing 2 or 3 strains of the Flu, but increases risk of contracting hundreds of other strains and probably almost all other viruses. Read more on this study:
www.leanmachine.net.au/healthblog/prestigious-vaccine-journal-flu-vaccine-increases-coronavirus-infection-risk-36

Do not touch your face, especially near eyes, nose, mouth and even ears. The average person touches their face 23 times every hour. Medical masks can help in stopping touching of mouth and nose. If no masks are available, a clean super-size handkerchief will help. Looking like a cowboy should not bother anyone unless you are walking into a bank…

Do NOT eat Sugar because, blood lab tests show a lowered immune system function within 30 minutes of eating sugar, causing a 50% reduction in the ability for white blood cells to kill pathogens!
Read more about how sugar and insulin resistance causes Coronavirus deaths:
www.leanmachine.net.au/healthblog/the-real-pandemic-is-insulin-resistance

Heat

I have already discussed the benefit of having a fever, but there are easy ways to create a fever if the body is not automatically doing it.

  1. Exercise heavily enough to sweat
  2. Use an infra-red Sauna. Infra-red heat penetrates deep into the body, increasing the white blood cells and immunity

Hand Sanitisers

I rarely use hand sanitisers, only when there is no opportunity to wash hands, but I regularly wash hands because I work hard and get dirty a lot! Grime on hands can hide many unknown bacteria and viruses, so washing hands regularly is important, but not too much, as the natural protective oil (sebum) in skin is depleted, allowing pathogens to enter the blood directly through the skin. Hospitals have hand sanitisers at the entrance, but it is best to use these on the way out to protect against MRSA and other infections that we pick up in hospitals because of the over-use of antibiotics and sterilising agents. When we get home, forget the Sanitisers and wash hands in soap and hot water.

Commercial hand sanitisers have many problems:

  • They almost always have toxic ingredients such as Tricoslan that can cause cancer, hormonal imbalance and can increase absorption of BPA (Bisphenol A) that introduce excess synthetic estrogens
  • Most contain Phthalates and Parabens that damage the endocrine system, causing early onset puberty, obesity and cancer
  • They are generally only 99.7% effective, but washing hands in soap and water is 99.2% effective anyway
  • According to a 2013 FDA study, chemical-based anti-bacterial hand soaps/sanitisers have never been proven to be any more effective than washing with natural hand soap. The best soap is a non-toxic hand soap with natural ingredients like Eucalyptus Oil Soap
  • Soap effectively kills COVID-19 and most other viruses by dissolving the fatty membrane that holds the virus together, causing it to fall apart and is washed off under running water
  • We need good bacteria for a strong immune system, and grabbing a shopping trolley or doing some gardening is a good way to build the immune system
  • Sterile hands are a recipe for infection as we need the good bacteria to help defeat the bad bugs
  • Sanitisers are more effective against bacteria and may have limited effect against viruses
  • Intended to ward off bacterial infection, these products have backfired. Prolific use of sanitisers promotes bacteria becoming resistant such as MRSA
  • Sanitisers are associated with allergy development in young children
  • Sanitiser chemicals leach into the environment, ending up in our tap water, rivers, lakes and oceans

washing handsIf you still want to use a sanitiser, here is just one of the many recipes available that has no toxic ingredients:
Homemade Hand Sanitiser

Instructions:

  1. Add 20 drops of tea tree oil, 5 drops of lavender oil, 5 drops of lemon oil, and 5 drops of sweet orange oil to the glass bottle.
  2. Gently swirl the oils together. Slowly pour witch hazel into the spray bottle until it is about 2/3 of the way full.
  3. Add aloe vera until the bottle is full. If desired, add a few drops of vitamin E oil; it extends the shelf life and adds antioxidants.
  4. Put the lid on the bottle and shake it to mix the ingredients. Label the bottle and store it in a cool, dry place for up to two months.
  5. Use it before touching surfaces or when it is not possible to wash hands with soap and water.

Sanitisers can be valuable only if there is no soap and water available.

Face Masks

Face masks may help reduce transmission of disease in crowded areas, but given social distancing, there should be no need. However, one advantage of the masks is that they help prevent a person touching their mouth or nose. One study found that people on average touch their face 38 times per hour without being aware.
Home made masks are easy to make and work nearly as well as commercial masks. More mask info:
www.leanmachine.net.au/healthblog/benefits-of-wearing-masks-for-protection-from-infection

May GibbsAn original May Gibbs drawing from 1919 which she drew for the Spanish Flu epidemic.
© The Northcott Society and Cerebral Palsy Alliance 2020
This image is under copyright and cannot be used for commercial purposes without permission.

Do Not Panic

Fear and Panic lowers our immunity and drives us to make irrational decisions.

Fear creates high levels of Cortisol and Adrenaline, which enables us to perform in “fight or flight” situations. This is a good thing if we are faced with immediate danger, but a bad thing if the levels do not return to normal in a few hours because our immune system will be compromised  with consistently high levels.
For any healthy person, Coronavirus will be no worse than the common cold.
Good nutrition, clean air, clean water and some supplements above will either prevent infection or substantially alleviate symptoms. The only people who may die from Coronavirus are those with a compromised immune system, and if Coronavirus did not exist, the they would probably die from the flu, cancer, Alzheimer’s, vaccinations, cardiovascular events, or even the original Coronavirus or Rhinovirus (common cold) etc.

Danger of Lockdowns

Given that 99% of deaths are caused more from existing medical conditions and prescription drugs and false death records, and the fact that the seasonal flu kills as many or more, and that at least 10 times that many deaths are caused by medical mistakes, infections caught in hospitals, and almost all people who died from Coronavirus would have died anyway, is it wise to destroy the world’s economy and cause millions of people to lose jobs and possibly homes, more deaths from suicide, mental problems, marriage breakups and more; what is the real cost?
Read more:
www.leanmachine.net.au/healthblog/systems-biologist-speaks-out-about-covid-19-response

Other Infections

There are many conditions that are far worse than Coronavirus. 5 times more people die from the Flu than Coronavirus, but we have never had lockdowns for the Flu except some Nursing Homes, where all patients and staff have had compulsory Flu vaccinations (proving that the vaccinations do not work).

Hospitals all over the world are concerned with Candida Auris (C. Auris), a fungal yeast infection that is spreading and killing many people. Major anti-fungal medications do not work, and nearly half of all who contract it die within 3 months.
First found in Tokyo in 2009, it has spread across Asia and Europe, and to the USA in 2016.
For general Candida Albicans infections, read my Candida Article.
Solutions for Candida Albicans may not work for Candida Auris, but will probably do no harm, and may help.

Why Hard Water Decreases Heart Attacks


Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2020/01/20/magnesium-linked-to-better-heart-health.aspx

Analysis by Dr. Joseph Mercola     Fact Checked

January 20, 2020

STORY AT-A-GLANCE

  • Magnesium insufficiency has been linked to a higher risk for high blood pressure, cardiovascular disease, arrhythmias, stroke and sudden cardiac death
  • Research has shown people drinking soft water on a regular basis are more susceptible to lethal arrhythmias (irregular heartbeat) than those drinking hard water. One hypothesis that can account for this is magnesium deficiency, as hard water contains higher levels of magnesium than soft water
  • Magnesium supports heart health by combating inflammation (which helps prevent high blood pressure and hardening of your arteries) and improving blood flow by relaxing your arteries and preventing your blood from thickening
  • Magnesium also plays a role in the creation of adenosine triphosphate (ATP), the energy currency of your body. Being a heavy energy user, your heart needs sufficient amounts of ATP to function properly
  • Magnesium also affects your mitochondrial function and health, as it’s required both for increasing the number of mitochondria in your cells and increasing mitochondrial efficiency

When it comes to heart health, one of the most influential nutrients is magnesium. While required for the healthy function of most cells in your body, magnesium is particularly important for your heart, kidneys and muscles.

As far back as 1937, researchers warned that low magnesium levels pose serious risks to the heart, and that it may actually be the most significant predictor of heart disease.1 More recent research suggests even subclinical magnesium deficiency can compromise your cardiovascular health.2

Importantly, your mitochondria require magnesium to produce ATP. It’s also required for the metabolic function of your cells and the activation of vitamin D.3,4 All of these are important for healthy heart function.

It also supports heart health by relaxing your blood vessels, normalizing blood pressure, lowering inflammation and supporting endothelial function (the cells’ lining the interior of your blood vessels).5

Hard Water Linked to Better Heart Health

To celebrate its 175th anniversary, Scientific American recently took a look back into its archives, publishing a short summary of research presented in its June 1969 issue:6

“Several studies in the past decade have suggested that the death rate from coronary disease is inversely correlated with the hardness of the local water supply: the harder the water, the lower the coronary rate.

A study7 recently published in the New England Journal of Medicine reports evidence that the excess coronary deaths in soft-water areas are almost entirely sudden deaths …”

By reviewing the death certificates of 55,000 individuals who died from heart-related issues in Ontario during 1967, and then correlating the deaths according to the hardness of the local water supply, the Canadian researchers were able to conclude that people drinking soft water on a regular basis were more susceptible to lethal arrhythmias (irregular heartbeat). What might explain this curious correlation?

One theory has focused on the magnesium level found in the water.8 Soft water is lower in magnesium than hard water, thus making you more prone to magnesium deficiency. (The very definition of hard water is that it contains a high concentration of dissolved metals — calcium and magnesium in particular.9,10)

According to a 2002 study,11 magnesium-rich mineral water can contribute between 6% and 17% of your total daily magnesium intake. That said, a 2013 paper12 in the International Journal of Preventive Medicine points out that the exact mechanisms responsible for the relationship often found between harder water and lower cardiovascular risk has yet to be ascertained.

The higher magnesium level in hard water appears to be a promising hypothesis, though, and several studies point to magnesium-rich water being an important factor. As noted in the International Journal of Preventive Medicine, which cites a number of such studies (as well as some in which this relationship was not found):13

In a Swedish study, the skeletal muscle magnesium levels were a significantly higher in persons living in an area with a higher water magnesium.”

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Even Subclinical Magnesium Deficiency Can Be Problematic

As mentioned, magnesium supports heart health through a number of different mechanisms.14 For starters, it combats inflammation, which helps prevent high blood pressure and hardening of your arteries. It also improves blood flow by relaxing your arteries and preventing your blood from thickening.

Magnesium also plays a role in the creation of adenosine triphosphate (ATP), the energy currency of your body.15,16 Needless to say, without sufficient energy, cellular functions throughout your body will suffer, creating a cascade of dysfunction. Your heart in particular, being a very heavy energy user, needs sufficient amounts of ATP to function properly.

Magnesium also affects your mitochondrial function and health, as it’s required both for increasing the number of mitochondria in your cells and for increasing mitochondrial efficiency.

Basic effects such as these can account for why magnesium insufficiency has been linked to a higher risk for high blood pressure,17 cardiovascular disease, arrhythmias, stroke18 and sudden cardiac death.19

A 2018 paper20 in the Open Heart journal also warns that even subclinical deficiency can result in heart problems, and that most people need at least 300 milligrams more magnesium per day than the current recommended dietary allowance prescribes. According to the authors:

“… While the recommended … dietary allowance for magnesium (between 300 and 420 mg /day for most people) may prevent frank magnesium deficiency, it is unlikely to provide optimal health and longevity, which should be the ultimate goal.”

The theory that we may need more magnesium than is currently recognized is also supported by a 2016 meta-analysis,21 in which all-cause mortality was lowered by 10% simply by increasing magnesium intake by 100 mg per day.

Magnesium Is Important for Brain Health Too

Magnesium is also important for brain health and the prevention of dementia. Memory impairment occurs when the connections (synapses) between brain cells diminish. While many factors can come into play, magnesium is an important one. As noted by Dr. David Perlmutter, a neurologist and fellow of the American College of Nutrition:22

“It has now been discovered that magnesium is a critical player in the activation of nerve channels that are involved in synaptic plasticity. That means that magnesium is critical for the physiological events that are fundamental to the processes of learning and memory.

As it turns out, one form of magnesium, magnesium threonate, has the unique ability to permeate the brain and enhance the receptors that are involved in this process.”

The specific brain benefits of magnesium threonate were demonstrated in a 2010 study23 published in the journal Neuron, which found this form of magnesium enhanced “learning abilities, working memory, and short- and long-term memory in rats.” According to the authors:24

Our findings suggest that an increase in brain magnesium enhances both short-term synaptic facilitation and long-term potentiation and improves learning and memory functions.”

Magnesium is also a well-recognized stress reliever,25 and by catalyzing mood-regulating neurotransmitters like serotonin, it helps prevent anxiety and depression.26

Research27 published in 2015 found a significant association between very low magnesium intake and depression, especially in younger adults. A study28 published in PLOS ONE demonstrated magnesium supplementation improved mild-to-moderate depression in adults, with beneficial effects occurring within two weeks of treatment.

How to Assess Your Magnesium Status

When it comes to measuring your magnesium level, your best bet is an RBC magnesium test, which measures the amount of magnesium in your red blood cells. Tracking any symptoms of magnesium deficiency is also recommended, as your need may be higher or lower depending on your lifestyle and health status.

Common signs and symptoms of magnesium insufficiency include but are not limited to the following.29,30 A more exhaustive symptom’s list can be found in Dr. Carolyn Dean’s blog post, “Gauging Magnesium Deficiency Symptoms.”31

  • Seizures, muscle spasms (especially “charley horses” or spasms in your calf muscle that happen when you stretch your leg), eye twitches and or numbness or tingling in your extremities
  • Insulin resistance
  • High blood pressure, heart arrhythmias and/or coronary spasms
  • Increased number of headaches and/or migraines
  • Low energy, fatigue and/or loss of appetite

The “Trousseau sign”32 can also be used to assess your magnesium status. To check for this sign, a blood pressure cuff is inflated around your arm. The pressure should be greater than your systolic blood pressure and maintained for three minutes.

By occluding the brachial artery in your arm, spasms in your hand and forearm muscles are induced. If you are magnesium deficient, the lack of blood flow will cause your wrist and metacarpophalangeal joint to flex and your fingers to adduct. For a picture of this hand/wrist position, see Figure 1 in the paper “Trousseau Sign in Hypocalcemia.”33

Would You Benefit From Magnesium Supplementation?

A number of studies suggest magnesium insufficiency or deficiency are extremely common, both among adults34 and teens,35 in part due to the fact that most people eat a plant-deficient diet. Magnesium is actually part of the chlorophyll molecule responsible for the plant’s green color.

However, even if you eat plenty of greens, you may still not get enough, thanks to most soils being so depleted of minerals. Your body’s ability to absorb magnesium is also dependent on having sufficient amounts of selenium, parathyroid hormone and vitamins B6 and D.

Absorption is further hindered by excess ethanol, salt, coffee and phosphoric acid in soda, and things like sweating, stress, lack of sleep, excessive menstruation, certain drugs (especially diuretics and proton-pump inhibitors), insulin resistance and intense exercise can deplete your body of magnesium.36,37

Research shows just six to 12 weeks of strenuous physical activity can result in magnesium deficiency,38 likely due to increased magnesium demand in your skeletal muscle.

For all of these reasons, most people probably need to take supplemental magnesium. The RDA for magnesium is around 310 to 420 mg per day depending on your age and sex,39 but many experts believe you may need a minimum of 600 mg per day.40

I suspect many may benefit from amounts as high as 1 to 2 grams (1,000 to 2,000 mg) of elemental magnesium per day, as the extra magnesium may also help mitigate unavoidable exposures to electromagnetic fields (thanks to its calcium channel blocking effect). To learn more about this, see my previous article on how to reduce EMF exposure.

You can easily improve your magnesium status with an oral magnesium supplement. My personal preference is magnesium threonate, as it appears to be the most efficient at penetrating cell membranes, including your mitochondria and blood-brain barrier. You can learn more about this in “Cognitive Benefits of Magnesium L-Threonate.”

Magnesium Testing Is a Valuable Health Screen

Considering the importance of magnesium for good health — including cognition and heart health — it’s a good idea to measure your level. GrassrootsHealth Nutrient Research Institute, which has spearheaded research into vitamin D and omega-3, now also offers low-cost testing for magnesium.

Join Magnesium* Plus Focus Project today!

Like its vitamin D and omega-3 projects, the Magnesium*PLUS Focus Project41 aims to identify the ideal dosage and level, the specific health outcomes associated with magnesium deficiency and sufficiency, the dose-response relationships and much more. As noted by GrassrootsHealth:42

“Measuring your nutrient status, adjusting intake as needed, and re-testing is the only way to tell if your nutrient intake is helping you achieve sufficient or desired nutrient status which is tied to particular health outcomes.

We will analyze the collected data and give participants feedback on how the magnesium could be working for them; we will publish scientific papers on key results, the first after meeting an enrollment target of 1,000 participants. There will be preliminary analyses and interim newsletters available for all during the enrollment phase.”

Adding the “Plus Elements” test to this magnesium test will also measure your selenium, zinc and copper levels, important trace elements that interact with magnesium, as well as three toxic heavy metals (lead, cadmium and mercury) that can interfere with and block availability of these essential elements.

Magnesium* Plus Elements Project

Alzheimer’s Prevention

Written by Brenton Wight, researcher and LeanMachine

Copyright © Brenton Wight, LeanMachine

Doctors say there is no cure for Alzheimer’s Disease, in spite of over 80 billion dollars in research over the last few decades.
This is partly true, as there is no drug, no “magic bullet” to slow or stop this dreadful condition.
Hundreds of studies with new drugs have shown most of the time that those on a placebo did BETTER than those on the drug!
In rare cases, those on the drug did very slightly better, but any improvement was not enough to justify bringing the drug to market.
However, we CAN identify risk factors, and we CAN in most cases prevent the onset of Alzheimer’s, and we CAN in most cases reverse the disease, or at least ease the symptoms to give the patient and the carers a better quality of life.
If the intervention is soon enough, it CAN be CURED in some, but not all cases.
There is no miracle one-shot treatment, but a combination of many factors.
The time to start treatment is not when we are 60 and forget where the keys are, but from birth!
The lifetime changes we need to prevent Alzheimer’s will also prevent heart disease, diabetes, cancer and many other diseases, and give our lives vitality.

How many people are at risk?

In the USA, over 5 million Americans have Alzheimer’s disease, and around 14% of the population will eventually get Alzheimer’s, or around 45 million people.
Results in Australia are similar. Over 10% of the population over 65 have Alzheimer’s, and 30% of those over 85 have Alzheimer’s. In the decade from 2010 to 2020, deaths from Alzheimer’s has risen 20% and looks set to replace Cardiovascular disease as the Number 1 cause of death.
Many people now suffer from Early Onset Alzheimer’s, showing signs as young as 30 years of age.
In the USA, it is now the third leading cause of death, but these figures are understated. People do not actually die from Alzheimer’s – they die because the parts of the brain that control bodily functions shut down, so they die when their organs shut down.
The patient may die from pneumonia because the lungs now cannot function or some other organ fails to work and the Doctor or Coroner has to determine which organ failed.
This is a problem in every country, but some countries have very much reduced rates of Alzheimer’s, mainly due to better diets and reduced toxins.

Diagnosis

Originally, there was no firm diagnosis without examining the brains of patients after death.
Researchers found that most patients had Amyloid Plaques in the brain, and also high levels of aluminium.
PET scans (Positron Emission Tomography) are used with a radioactive tracer (which binds to amyloid plaques) to determine the amount and location of amyloid plaques in the brain.
However, this diagnosis is still not conclusive, as many people have amyloid plaques, but no sign of any dementia even into old age, although these people have a higher risk. Often symptoms do not appear for decades after the start of amyloid plaque deposits. Other patients have no sign of Amyloid plaques but still have Alzheimer’s, so drugs developed to reduce Amyloid plaques have proven unsuccessful in prevention and treatment.
Standard blood tests for glucose level, triglycerides, kidney and liver function can help determine the risk. However, those with less than optimum blood results may die of Cardiovascular, Cancer or some other disease before Alzheimer’s sets in.
So the PET scan is used with other tests for cognitive performance to arrive at a diagnosis.

Who is at risk?

Genetics plays an important part, and so does diet, exercise, lifestyle and supplements.
Here are some risk factors, in no particular order:

  • Age is the greatest risk factor. Dementia can affect about 10% of those over the age of 65, but 33% of those over 80
  • Gender – Women represent over 60% of Alzheimer’s patients, but part of this may be due to their longer lifespans
  • Gluten – Celiacs often have “Wheat Brain” causing disturbances, anxiety, depression and Alzheimer’s. Many dementia patients recover fully on a gluten free diet
  • Prescription medications such as many sedatives, hypnotics, blood pressure, hay fever, insomnia, depression and arthritis medications are linked to higher risk of Alzheimer’s
  • Anaesthetics are linked to Alzheimer’s. The more operations people have, the higher the risk
  • High Blood Pressure (systolic over 140 in mid-life) doubles the risk of Alzheimer’s and increases vascular dementia by 600%, but blood pressure medications can be just as bad, so reduce it naturally without medication
  • Sleep Apnea starves the brain of vital oxygen and increases risk of Alzheimer’s
  • B-12 deficiency increases Alzheimer’s risk. Gastric Bypass Surgery, Celiac disease, vegan/vegetarian diets, antacids (like Nexium) and many medications all reduce availability and/or absorption of B-12
  • Diabetes doubles the risk of Alzheimer’s (often called “Diabetes of the Brain” or “Type 3 Diabetes”)
  • Vision problems increase Alzheimer’s risk. Opthalmologists can detect abnormal widths of blood vessels in the retina which can indicate early Alzheimer’s
  • Tobacco – Smokers have double the risk for Alzheimer’s. Family and others breathing second-hand smoke also have higher risk
  • Living alone after a partner’s death means we have six times the risk of Alzheimer’s, and those who divorce and live alone have three times the risk.
  • Isolation is a significant risk factor for depression and dementia. Find a friend!
  • Obesity is a risk. The lower the BMI (Body Mass Index) the lower the risk. Obesity raises risk by around 75%
  • Family history increases the risk. See the Genetics section below, but environmental factors, diet and lifestyle choices can be passed on to children
  • Education improves outcome, and lack of education increases Alzheimer’s risk. Studies suggest higher education increases “cognitive reserve” which may offset dementia symptoms
  • Concussion or head trauma increases Alzheimer’s risk exponentially with the number and severity of head injuries
  • Quality sleep is essential for the ability of the body to repair itself by flushing toxins from the brain
  • Excessive alcohol consumption can lead to alcoholic dementia and higher risk of Alzheimer’s as well as many other health risks
  • Mental activities improves the brain, physically and psychologically. Learn new things strengthens and develops new nerve cells
  • Sedentary lifestyles are a large risk for the brain as well as the body. Exercise is a must for the brain and the body
  • Chronic bladder disease increases risk
  • Chronic Candida infections increase risk

Overcoming risk factors:

  • Change the diet – see below
  • Get regular, uninterrupted sleep
  • Socialising, visiting friends, joining a group
  • Crosswords, puzzles, new experiences, learning a musical instrument or another language
  • Exercise helps control blood glucose levels, keeps excess weight down, increases oxygen and circulation, and joining a gym can also help with socialisation
  • Use the many supplements available

Genetics

There is a strong genetic predisposition to Alzheimer’s, but also there is a strong contribution of environment, diet and lifestyle.
Rates of Alzheimer’s disease have increased much faster than any genetic changes could have occurred.
This means that much is under our control, because even with a genetic predisposition, we can reduce risk with epigenetic (non-genetic influences on gene expression) changes.
Example: The most important genetic risk factor is the ApoE epsilon 4 allele (ApoE4), and 14% to 18% of the population has this gene.
Everyone carries two copies of the APOE gene, which makes the protein ApoE (apolipoprotein E).
There are three different types (alleles) of the APOE gene: E2, E3 and E4, and because we all have two copies of the gene, the combination determines our APOE “genotype” which can be any combination of the 2 copies: E2/E2, E2/E3, E2/E4, E3/E3, E3/E4, or E4/E4.
The majority of people have two E3 alleles (E3/E3) so this is defined as the “average risk”.
The E2 allele is the least common form, and if we have two E2 alleles (E2/E2) or one E2 and one E3 (E2/E3) we have about 40% REDUCED risk of Alzheimer’s.
The E4 allele, present in 14% to 20% of the population, increases the risk for Alzheimer’s, especially late-onset Alzheimer’s, but this does NOT mean that we will get Alzheimer’s disease if we have one or two copies of E4, as about one third of Alzheimer’s patients do not have even a single E4.
All it means is that our risk is increased, also increased is the risk of potential Alzheimer’s at a younger age.
To quantify the risk:
If we have no copies of E4, we still have around 9% risk of Alzheimer’s.
If we have a single copy of E4, our risk increases to around 30%.
If we have two copies of E4, risk is between 50% to 90% but in all cases, we CAN REDUCE the risk.
Many people are horrified to learn that they have up to a 90% risk of Alzheimer’s, but they need not be.
With some dietary, lifestyle and supplement changes, those at greatest risk can easily fall into the 10% who do NOT get Alzheimer’s.

SAD (Standard American Diet)

Genetic statistics above apply only to average people, typically Caucasians living in the Western World and consuming a typical Western diet of processed food, sugar, MSG, hydrogenated oils, chemicals, heavy metals, pesticides, insecticides and other toxic substances.
These statistics do NOT apply to those with a healthy diet of natural, organic food living in a low-toxin environment.
In fact, many people already down the cognitive decline have recovered on a healthy diet and sustained the improvement for several years, according to Dr Dale Bredesen who has been running a program for years now.
Dr Bredesen does not know how many more years it will be, but does know that patients on the program have removed the biochemical drivers which can be measured in blood tests, so so is very optimistic about their future health for many years to come.

Should we get genetic testing?

This is up to the individual. Some people would prefer not to know. Others want to know.
My father died from Alzheimer’s at about age 72 after many years in a Nursing Home, existing but without knowing who his family members were. So did my Grandmother on my Mother’s side, so I assume I may well have inherited a high genetic risk. I am now 73 as I revise this article. For me, testing is irrelevant, because I changed to a Paleo-style diet at age 63, which turned my life around.
From obese to lean, from grey hair to brown, from allergies to everything to allergies to nothing, from high blood pressure and triglycerides to normal, from poor physical strength to strong, fit and full of energy, from frequent headaches to none, from always getting sick to never getting sick.
If I had the genetic test and it was the worst result, I would only continue to do what I am doing now, using dietary and lifestyle modifications.
Have I halted Alzheimers? I hope so, but I often cannot remember some of the thousands of medical terms I have come across in my 10 years of research.  Come back here in 27 years as I approach 100 and I will let you know how I have done.

Amyloid Plaques vs Tangles

Amyloid is a protein, normally found throughout the body. In Alzheimer’s, this protein divides improperly, creating beta amyloid which is toxic to brain neurons.
Amyloid is actually antimicrobial and has benefits for the body, but some people, especially those with the E4/E4 alleles cannot naturally break down these plaques, but there are dietary methods which can.
Not all Alzheimer’s patients have beta Amyloid plaques. About 10% of patients have neurofibrillary tangles which cause similar symptoms, but are also inclined to have more aggressive behavior.

Three Kinds of Alzheimer’s

Humans liberate amyloid as a protective response in the body to three different fundamental metabolic and toxic perturbations:

  • Type 1: Characterized by systemic inflammation. Blood tests typically reveal high hs-CRP (high-sensitivity C-reactive protein), low albumin:globulin ratio,
    and high cytokine levels such as interleukin-1 and interleukin-6. Imaging reveals temporoparietal reductions in glucose utilization.
    Those at risk include people with chronic infections or inflammation from other causes, and the normal antimicrobial protective response liberates amyloids
  • Type 2: Characterized by normal inflammation, but an atrophic (wasting away) profile, with reduced support from estradiol, progesterone, testosterone, insulin, and vitamin D, often with high homocysteine and insulin resistance. Imaging reveals temporoparietal reductions in glucose utilization. As NGF (Nerve Growth Factor) diminishes, amyloid production increases.
    Type 2 in particular can be CAUSED by LOW cholesterol, resulting in atrophy (brain shrinkage), reduced hormone production, poor health and eventually Alzheimer’s.
    All because we are taking statins that lower cholesterol, or we are not eating enough healthy fats.
    We prevent our cells from doing what they are supposed to do, so we end up with a shrunken brain without the lipid (fat) content we need. A fat-free diet means atrophy of the brain.
    See the Cholesterol Fraud and the Big Fat Lie sections below.
  • Type 3: Different from types 1 and 2. Still β-amyloid positive and phospho-tau positive), but a younger onset (late 40s to early 60s).
    Genotype ApoE is usually E3/E3 instead of E4/E4 or E3/E4 with little or no family history.
    Onset usually follows a period of stress, depression, sleep loss, anesthesia, or menopause/andropause.
    Memory loss is not a main symptom, instead there are cortical issues: dyscalculia (trouble with arithmetic), aphasia (trouble speaking or understanding speech – damage to the left side of the brain),
    executive dysfunction (emotional or behavioural problems from frontal lobe issues).
    Imaging studies often reveal extra-hippocampal disease, greater general cerebral atrophy and frontal-temporal-parietal abnormalities.
    Lab results often reveal hypozincemia (low zinc) and/or a high copper:zinc ratio, and can indictate adrenal fatigue
    (low pregnenolone, DHEA-S (dehydroepiandrosterone sulfate), and/or AM cortisol. Chronic infections like mycotoxins, Lyme, viral infections, HSV-1 (a herpes simplex virus) are all risk factors


Some patients have “Alzheimer’s type 1.5” where a combination of symptoms of both type 1 and 2 Alzheimer’s occurs.
Glycotoxicity (too much sugar in the brain) causes an insulin resistant brain. Combine this with AGEs (Advanced Glycation End products), and we have both inflammation from AGEs, plus atrophic withdrawal response because we are now resistant to insulin.
So we have a double condition of type 1 and type 2.

Type 3 patients often have MARCoNS (Multiple Antibiotic-Resistant Coagulase-Negative Staph), a colonisation of antibiotic-resistant staphylococcus in the nasal cavity.
Also high blood levels of TGF-beta-1 (Transforming Growth Factor beta-1), high C4A (a protein that in humans is encoded by the C4A gene), and low MSH (Melanocyte-Stimulating Hormone) is very common, typically with HLA-DR/DQ haplotypes shown by Dr Ritchie Shoemaker to be associated with CIRS.

Alzheimer’s from nose infections?

We have known for years that our healthy gut bacteria is essential to prevent almost every disease, and now research is looking at the rhinosinal microbiome, the healthy bacteria in our nose.
This is now becoming known as Inhalational Alzheimer’s.
The nose is the most direct route to the brain, and bad bacteria in the mucous lining of the airways can damage the brain.
Pathologists now believe there are unknown pathogens in the rhinencephalon, the “nose-smell” (olfacation) system.
Many Alzheimer’s patients start losing their sense of smell as one of the early signs of the disease, and this is probably why.
I am confident that my nasal bacteria is back to normal after having very bad allergies and taking antihistamines from when I was about 16 to when I was 63.
Allergies stopped when the bad diet stopped.

Dr. Susan Lynch at UCSF has found that the nose problem is not so much an unknown pathogen, but a lack of microbial diversity.
Beneficial microorganisms in the nose protect against many pathogens, and one of the best seems to be Lactobacillus sakei, used to make sake and kimchi.
This could explain why Japanese people have comparatively low rates of Alzheimer’s, although rates are rising in Japan because of the Western influence, with meat and dairy replacing rice as a staple food.
When Japanese people migrate to Western countries and adopt a Western diet, they have the same risk as anyone else.
So for the Japanese, it is not a genetic problem, but a diet problem, and this applies to everyone.

AGEs – Advanced Glycation End products

AGEs are formed when food cooked at high temperatures (over 120 degrees C) combines with sugar. AGEs are very damaging to the body, accelerating the ageing process and chronic disease.
AGEs worsen diabetes, kidney disease, Alzheimer’s, inflammation, atherosclerosis (stiffening of the arteries), cardiovascular disease and stroke.
AGEs cause glycation of LDL cholesterol, promoting oxidation, and oxidized LDL is a major factor in atherosclerosis.
AGEs form photosensitizers in the eye lens, leading to cataract development.

To reduce AGEs, never cook at high temperatures (steaming is best, always at 100 degrees C), eat plenty of raw food (salads, and small amounts of fruit), and eliminate all sugar and processed foods.

Conventional Drugs

Drug companies have been trying for years to get rid of Amyloid plaques, thinking they are the cause of Alzheimer’s.
However, the body needs amyloid to protect the brain, so we need to look at what is causing the plaques instead of trying to get rid of them. Latest research shows that Amyloid plaques are antimicrobial, so can be both damaging and protecting!

 

Alzheimer’s – “Diabetes Type 3”

Some researchers are now labeling Alzheimer’s as “Diabetes Type 3” because sugar causes Alzheimer’s.
Sugar also causes diabetes, cardiovascular disease, obesity and many more diseases, mainly due to processed foods.
As with diabetes, where sugar causes insulin resistance, we have insulin resistance in the brain, causing degeneration.
When the brain becomes insulin resistant, it means that glucose cannot enter the brain cells, so those cells die.
However, all is not lost. If we switch to a Ketonegic diet, we can feed our brain with fat instead of sugar. More on this diet below.

Diagnosing the type of Alzheimer’s

Unlike cancer, where we can biopsy a tumour, we must look at historical, biochemical, genetic, imaging, and function information to determine the type of Alzheimer’s.
Of course this rarely happens except in research applications. The doctor simply says the patient has Alzheimer’s and may give a drug which in the long term will not make much difference.
This is a shame, because about half of all cases can be halted, and in some cases substantially improved, by reverting to the correct diet.
Even better would be to eat a correct diet from birth, reducing the risk of Alzheimer’s to near zero, as well as preventing cancer, heart disease, diabetes and other modern diseases.

Exercise

Physical exercise is extremely important to keep the brain and body healthy.
Researchers are not sure why, but LeanMachine says it is obvious:
Exercise burns off the high glucose levels that cause “Diabetes of the Brain” and exercise boosts oxygen levels and circulation in the brain.
Any type of exercise is beneficial, such as:

  • Walking, jogging or running
  • Calisthenics
  • Squats
  • Push-ups, chin-ups
  • Skipping
  • Gardening

Exercises have the added benefit of socialisation in a group, such as:

  • Join a gym
  • Tai-Chi or Yoga classes
  • Athletics clubs
  • Dancing classes

Exercising the Brain

The body has a disturbing property: Anything not used for a while gets broken down to be used somewhere else.
If we do not use a muscle for a week, the body starts breaking it down.
But if we exercise regularly, we stop muscles wasting, and we actually build up our muscles.
If we do not use parts of the brain, the body starts breaking it down.
But if we exercise our brain, we can hang on to the parts we use, and develop new pathways to replace parts we have lost. Exercises such as:

  • Learning a new language
  • Playing a musical instrument
  • Crossword or other puzzles
  • Socialising in groups or clubs

Meditation

Meditation is not normally seen as exercise for the brain, but sitting in a quiet, dark room away from all daily distractions not only promotes a calming effect, but increases various brain-saving hormones.
Meditation, like dreaming, helps the brain sort out the junk memories and recent problems by concentrating on things that have made us feel good in the past.
We may have pleasant memories like sitting on a sandy beach listening to the waves rolling in on a beautiful sunny day. By concentrating on peaceful and pleasant memories, we forget problems with out hectic daily life.

Supplements

The modern diet is lacking in vitamins, minerals, amino acids and other nutrients, mainly because of:

  • Over-farming – growing the same food in the same ground year after year, depleting these vital elements
  • Over-processing – hydrogenation, adding sugar, adding chemicals, overheating
  • Toxins from farming chemicals contaminates the environment
  • Water is contaminated by fluoride and chlorine

The supplements everyone over 50 should take are:
Organic Coconut Oil, taken several times a day, a tablespoon at a time.
LeanMachine considers this one of the best prevention and treatment methods available for Alzheimer’s.
This encourages the body to burn healthy fats instead of sugar, called the Ketogenic Diet which burns ketones, which is what our ancestors did in their natural low-carb diets. See the Ketogenic Diet below.
Coconut oil appears to break down the amyloid plaque buildup in the brain. Perhaps the plaques are no longer required when the brain is fed by healthy fats instead of glucose.
Coconut oil is also the absolute best for cooking, replacing any other fat, because coconut oil remains stable at high temperatures, and is full of MCT (Medium Chain Triglycerides) which go straight to the liver to be burned as fuel, and cannot be stored as fat in the body.
Coconut oil also contains Lauric Acid, which keeps our skin wrinkle-free and healthy.

PS (Phosphatidylserene) is a component of the cerebral cortex’s neuronal membrane, and can improve memory and mood, reduce stress, improve learning and more.
It does this by controlling input and production of choline, acetylcholine, norepinephrine, dopamine and glucose.

NAC (N-Acetyl Cysteine) which helps the body make Glutathione, the body’s natural “Master Antioxidant” that fights cancer, Alzheimer’s and many other conditions.

Curcumin is the active ingredient in Turmeric which has been used for thousands of years for dementia, cancer and many other conditions.

Vitamin B-12 because as we age, our stomach acid levels drop, preventing the high-acid conditions required for B-12 absorption from food. Even more essential for vegans and vegetarians as B-12 mainly comes from animal products.

B-group vitamins because these are vitally important for nerves and brain health.

ALA (Alpha Lipoic Acid) as an antioxidant to help remove heavy metals from the brain, reduce inflammation, and improve the effectiveness of votamins C and E.

Vitamin D3 because over half the ageing population are taking statin medication (which they should NOT) and statins halt production of 7-dehydrocholesterol, the first step in the manufacture of vitamin D3. Worse, many of these seniors are in Aged Care facilities and never see the light of day, so cannot make vitamin D3 from sunlight. If they are ever taken outside, it is only early morning or late afternoon when they cannot get vitamin D3 anyway. More info in my Vitamin D3 article.

Ginkgo Biloba is highly recommended to improve blood flow in the brain. Should not be used in conjunction with prescription blood thinners.

TMG (Trimethylglycine) is an effective methyl donor for the facilitation of methylation processes. Supports a healthy homocysteine level, which in turn supports healthy cardiovascular function and helps prevent Alzheimer’s. Homocysteine, a damaging amino acid, with the aid of TMG, is turned into methionine, a safe and beneficial amino acid. Methylation is essential for DNA repair and production of SAMe, which helps joints, lifts mood, fights depression and protects brain cells from amyloid plaques. Read more in my TMG article.

SAMe (S-Adenosyl Methionine) can help protect the brain and also help treat depression, anger, anxiety which are common symptoms in some Alzheimer’s patients.

Vinpocetine has shown mixed results but mostly beneficial in limited human trials using 10mg 3 times daily.

Vitamin E is recommended to improve the healthy fats in the brain and increase antioxidants.

Benfotiamine with Leucine can help remove glucose and improve insulin resistance.

Many other supplements can help, including:

In addition, many supplements primarily used to treat diabetes will also help prevent Alzheimer’s.

The Cholesterol Fraud

Previous research indicated that high cholesterol was a risk factor for Alzheimer’s.
Again, this was wrong. Doctors started prescribing statin drugs for those people with high cholesterol, or those with signs of dementia with normal cholesterol.
What happened? They got Alzheimer’s WORSE and got it FASTER than patients who did NOT take statins.
Researchers only looked at total cholesterol which is a complete waste of time.

25% of the cholesterol in the body is in the brain, mainly in the myelin sheath.
Around 60% of our brain is fat, mainly in the form of cholesterol.
The myelin sheath (oligodendroglia) that surrounds and protects our neurons are 70% cholesterol, 30% protein.
Starve the brain of healthy fat, and we get Alzheimer’s. Almost guaranteed.
Reduce cholesterol and what happens? The protective myelin sheaths break down as they are starved of cholesterol, allowing the brain cells to be damaged. Damage them enough, and they die. Then we have dementia. Damage enough cells, and the brain can no longer support our basic functions, like breathing. Then we die.
This is why statin drugs are BAD.
Sure, in some cases, they can slightly reduce risk of heart attacks, but they INCREASE death from all other causes, including Alzheimer’s.
The net result is that on average, we will not live a day longer on statin medication.
Statins will give us lousy final years with muscle breakdown, osteoporosis, more sickness and dementia.
We need plenty of healthy fats like coconut oil, walnuts, avocados, fish, eggs, butter from grass-fed cows, unheated olive oil.
We must NOT consume bad fats: Canola oil, margarine, anything hydrogenated, anything heated over 120 degrees C.
Cholesterol is NOT the enemy.
We NEED cholesterol, especially HDL (High Density Lipoprotein) cholesterol which reduces inflammation, and helps clean up the body (like a garbage collector). Without HDL Cholesterol, we die within 24 hours.
We also need LDL (Low Density Lipoprotein), still incorrectly called “bad” cholesterol, as we die without it.
LDL has antimicrobial effects, so the idea that we should drive it down to zero is ludicrous. LDL is essential to transport nutrients around the body (and into the brain) as well as helping the body manufacture hormones and other important products. LDL was essential for our evolutionary ancestors millions of years ago, and we still need it.
The brain is mostly fat, and 40% of the brain is CHOLESTEROL.
Many things that were protective in our native environment are problems in our modern environment, but if we go back to our ancestral diet, problems are resolved.
Studies show time after time that people with low cholesterol die young, while people with normal to high cholesterol live longest.
These studies are ignored by the big drug companies. Because statin sales make them billions of dollars, of course they continue the Big Cholesterol Lie, one of the biggest frauds in medical history. Their own study showed increased deaths and terrible side effects so they stopped the study short at that time, supposedly to “save patient’s lives” when the opposite was true.

The dangerous cholesterol is VLDL (Very Low Density Lipoprotein) which cannot easily be tested.
Because triglycerides contain some VLDL, labs estimate VLDL value by simply taking a percentage of triglycerides.
High triglycerides are much more of a danger signal than high cholesterol, and are almost always related to obesity, poor diet of processed foods, especially dangerous fats.

The Big Fat Lie

We have been told for decades that fat is bad for us.
Forget about “low fat” or “fat free” diets.
Another big fat lie, coming from a scientist who plucked figures out of a study to suit an argument he was proposing.
When the data was analysed completely, many decades later, it showed the complete opposite.
The largest and longest study in the world was the Framingham study which showed that those who ate the most fat lived longer than those who ate the least.
Fat is not unhealthy in general, in fact it is essential for health.
The UNHEALTHY fats are man-made artificial fats (margarine, Canola oil) and other processed fats that are hydrogenated to improve shelf life and heated to extremes during manufacture, often going rancid in the process, causing oxidised VLDL (Very Low Density Lipoprotein), the REAL dangerous “food”.
What is REALLY bad is carbohydrates, and when manufacturers remove fats from food, they replace them with carbohydrates, causing most “modern” diseases including Alzheimer’s and Diabetes.

The Ketogenic Diet

For the first two million years of human life on Earth, carbohydrate consumption was very low.
Carbohydrates were uncommon, with the majority of food being nuts, seeds, eggs, fish, fruit and vegetables. Meat was eaten very rarely when an animal was killed.
These people did not burn carbohydrates for energy, they burned FAT. In particular, ketones, the basis of the ketogenic diet.
A ketogenic diet means maintaining a fasting state of ketosis. Ketones are produced when the body is in a state of ketosis.
Ketones fuel cells using a different pathway from glucose.
Glucose has to have insulin to allow glucose into cells, but as we all should know, our typical modern diet is loaded with carbohydrates, forcing the pancreas into overdrive making enough insulin.
Eventually our cells become insulin resistant, so the pancreas produces even more insulin to force glucose into the cells, creating even more insulin resistance.
We are now a full-blown diabetic, and when the pancreas starts shutting down, we need insulin injections for the rest of our life.
However, when we feed the cells with ketones, they simply enter the cell naturally, and do NOT require insulin or anything else to do so.
This is critically important for five of our modern diseases: Obesity, Cancer, Diabetes, Cardiovascular and Alzheimer’s, all caused or aggravated by high blood glucose, bad fats and inflammation.
Ketones are also signaling molecules as well.

Benefits of the ketogenic diet include:

  • Helps the body express new restorative and healing genes
  • Reduces inflammation (underlying cause of nearly every disease)
  • Stimulates the immune system
  • Aids weight loss
  • Stops or slows degenerative disease
  • Reduces risk of Alzheimer’s, Cancer, Cardiovascular, Diabetes and Obesity

The Anti-Alzheimer’s diet

Spices

Add these spices to every meal possible.
Of course they will spice up any meal, but also help clear the brain of problems and reduce risk of cardiovascular disease, cancer, diabetes and many more modern illnesses.

  • Sage – one of the best brain-saving spices
  • Cloves – one of the most potent antioxidants
  • Curry – a blend of other great spices
  • Ginger – reduces inflammation and improves immunity
  • Turmeric – for colour, flavour and Curcumin
  • Ceylon Cinnamon – Better and safer than regular cinnamon

Ketogenic Diet – Healthy fats, intermittent fasting.
Read How Cyclical Ketosis can help combat Chronic Fatigue

Avoid Trans Fats
Read Trans Fats Linked to Increased Risk for Alzheimers

Avoid Processed Foods
Only shop in the greengrocer department at the Supermarket, preferably the organic section. Buy or grow your own real food. Nothing in a bag, box, tin because toxic ingredients are sure to be added.

Avoid AGEs
Forget fried foods. Steaming is the best way to cook. Never Microwave. Eat raw salads daily.


This section often updated. Please come back soon (if you remember!)

LeanMachine online supplements

Updated 20th January 2020, Copyright © 1999-2020 Brenton Wight and BJ&HJ Wight trading as Lean Machine abn 55293601285

76 Evidence-Based Health Benefits of Noni

© 3rd January 2020 GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here www.greenmedinfo.com/greenmed/newsletter
Reproduced from original article:
https://www.greenmedinfo.com/blog/76-evidence-based-health-benefits-noni
Posted on: Friday, January 3rd 2020 at 4:15 pm

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.

Fibromyalgia

What is Fibromyalgia?

Fibromyalgia is a chronic condition, typically very painful, especially in response to pressure, and sometimes patients have symptoms like stiff muscles, joints and connective tissues.
Other symptoms often include depression, anxiety, sleep disturbance, difficulty swallowing, bowel and bladder problems, numbness and tingling, muscle spasms or twitching, weakness, nerve pain, palpitations,
cognitive dysfunction (“foggy thinking”).
Around 2% of the population are affected, usually between the ages of 20 and 50, although not all patients have all symptoms.
Women are nine times more likely than men to suffer from the condition, giving weight to the theory that hormones play a big part in the cause and treatment.
Diagnosis is difficult because there is no formal test. Symptoms are vague and similar to many other conditions.
Often patients with celiac disease are mistakenly diagnosed with Fibromyalgia, and do better on a gluten-free diet.
In fact, nearly everyone will do better on a gluten-free diet, or even better, a diet free from all grains, flour and any other product of grains, regardless of refined, wholemeal or any other form.
Some medical specialists say it is “all in the head” but few patients would agree with this!

Testing

Although there is no formal testing for fibromyalgia, the following tests should be arranged by the doctor to eliminate some factors that may indicate or aggravate Fibromyalgia:

  • Ferritin (Iron Study) – A serum ferritin level under 50 ng/ml means a 650% increased risk for Fibromyalgia
  • Thyroid Function – If autoimmune hypothyroidism is present, it should be treated first to see if Fibromyalgia symptoms subside
  • Other autoimmune conditions – Lupus, Rheumatoid Arthritis and others can resemble Fibromyalgia symptoms and should be treated first
  • CRP (C-Reactive Protein) – An inflammation marker. Source of any inflammation should be treated first
  • The FM/a blood test (plasma and PBMC (Peripheral Blood Mononuclear Cells) – Tests cytokine concentration. Low cytokines may indicate Fibromyalgia

Treatment

Doctors say there is no known cause or cure. However, some approaches can be very effective in reducing symptoms, including:

Therapeutic options

  • Mindfulness Training reduces psychological distress and depression
  • Yoga, Tai-Chi and other stretching exercises are helpful as they stimulate the lymph glands, increasing our HDL (good cholesterol), improving waste product and toxin removal, also reducing pain, fatigue, mood, cortisol levels and improves coping ability

Diet

  • Raw Food has been shown in studies to significantly improve the majority of fibromyalgia patients
  • Vitamin C and Broccoli consumption in a study found that the combination of 100mg of vitamin C from food, plus a 400mg broccoli supplement reduced pain by 20% and decreased 17% in Fibromyalgia impact scores

Things to avoid

Exposures to toxins definitely increase fibromyalgia risk:

  • Breast Implants have been linked to cancer, autoimmune disease, fibromyalgia and chronic pain
  • Aspartame (an artificial sweetener) should be eliminated from the diet, as it turns into formaldehyde in the body, which can aggravate fibromyalgia.
    Natural sweeteners such as Erythritol, Xylitol and pure Stevia are healthy alternatives
  • MSG (MonoSodium Glutamate) should be eliminated from the diet. Known to cause headaches and fibromyalgia
  • Vaccine Adjuvants containing mercury or aluminium have been shown to cause musculoskeletal pain conditions like fibromyalgia
  • Fluoride comes from fluoridated tap water, foods irrigated with fluoridated water, toothpaste, dental treatments and antibiotics, and must be avoided. A fluoridated water supply should be switched to rainwater and/or install a Reverse Osmosis water system for all drinking and cooking. Ordinary water filters do not remove fluoride, and even boiling water makes little difference

Prescription Medications increase risk

Many prescription medications increase risk of fibromyalgia, or actually cause it.

  • Statin Drugs reduce CoQ10 and vitamin D3, causing hundreds of health problems, including fibromyalgia and muscle pain, vastly outweighing any benefit in many cases
  • Prescription antidepressants like Celexa (Citalopram), Paxil (Paroxetine) and Prozac (Fluoxetine) include fluoride which makes fibromyalgia even worse, and causes weight gain.
    Antidepressants increase risk of cancer by over 40%, and most of the time do not work any better than a placebo
  • Many drugs contain bromide, which is even worse than fluoride, and more easily displaces iodine from the thyroid gland
  • Antibiotics destroy many bad bacteria, but also much of the good bacteria as well, compromising our immune system, which can take up to two years to rebuild
  • Paracetamol, Panadol, Tylenol and other names for acetaminophen should be avoided as studies show them to start causing liver issues even at the recommended dose two 500 mg tablets four times a day (4000 mg) for a few days. Unfortunately, patients who experience a lot of pain invariably over-dose, and just a 50% increase starts causing severe liver damage. The advertising slogan “safe and effective” is one of the biggest lies of the drug industry, and the most common cause of liver poisoning in the Western world. The majority of all patients on the liver transplant waiting list are there because of Panadol overdose. Panadol also reacts with an enzyme in the body to destroy our natural glutathione, which is one of the body’s main defenses against pathogens, often called the “master antioxidant”. Less glutathione means more Fibromyalgia

Here is a list of some drugs commonly prescribed that contain Fluoride or Bromide, two halogens that displace iodine from the thyroid and cause hypothyroidism, Hashimoto’s disease, depression, weight gain, hair loss, cancer, and will aggravate Fibromyalgia:

  • Advair (fluticasone) – fluoride
  • Alphagen (brimonidine) – bromide
  • Atrovent (Ipratropium) – bromide
  • Avelox (moxifloxacin) – fluoride
  • Adovart (dulasteride) – fluoride
  • Celebrex (celecoxib) – fluoride
  • Celexa (citalopram) – fluoride and bromide
  • Cipro (ciprofloxacin) – fluoride
  • Clinoril (sulindac) – fluoride
  • Combivent (from the ipratropium) – bromide
  • Crestor (rosuvastatin) – fluoride
  • Diflucan (fluconazole) – fluoride
  • DuoNeb (nebulized Combivent) – fluoride
  • Enablex (darifenacin) – bromide
  • Flonase (fluticasone) – fluoride
  • Flovent (fluticasone) – fluoride
  • Guaifenex DM (dextromethorphan) – bromide
  • Lescol (fluvastatin) – fluoride
  • Levaquin (levofloxacin) – fluoride
  • Lexapro (escitalopram) – fluoride
  • Lipitor (atorvastatin) – fluoride
  • Lotrisone topical cream – fluoride
  • Paxil (paroxetine) – fluoride
  • Prevacid (lansoprazole) – fluoride
  • Protonix (pantoprazole) – fluoride
  • Prozac (fluoxetine) – fluoride
  • Pulmicort (budesonide) – fluoride
  • Razadyne (galantamine) – bromide
  • Risperdal (risperidone) – fluoride
  • Spiriva (tiotropium) – bromide
  • Tobra Dex (from dexamethasone) – fluoride
  • Travatan (travoprost) – fluoride
  • Triamcinolone – fluoride
  • Vigamox (moxifloxacin) – fluoride
  • Vytorin (from eztimibe) – fluoride
  • Zetia (eztimibe) – fluoride

An immune response to intestinal bacteria may cause some symptoms, so an alkaline diet with plenty of enzyme-rich raw vegetables and fresh fruit may help, along with a little cheese, yogurt, whey, fermented vegetables such as Sauerkraut, and/or supplemental probiotics such as Acidophilus
to build up beneficial intestinal bacteria. 75% of our immune system is in the gut, and this is where the immune system often first breaks down.

MSG (monosodium glutamate) has been shown to aggravate symptoms, so most processed food, which contains MSG, often hidden in the ingredients list by being called other names or chemicals, should be eliminated.

Eliminating yeast from the diet may also help. Yeast is a raising agent found in most breads and other flour-based baked foods, also Vegemite. Changing to a fresh food diet of vegetables and fruit can eliminate yeast, lose excess weight, build immunity and improve general health.

Casein from milk and other milk products may also help, although some people are sensitive to dairy products and do better with no milk or other dairy products.

Food allergies can be a problem and I would start by eliminating wheat, flour, bread, cakes, anything made from flour, sugar, soy, milk, corn, eggs and nuts for at least a week or two.
If that helps, introduce them back into the diet one at a time (except sugar, which should be omitted forever, and all flour products), until the culprit is found.

If that is not enough, see my Vaccinations article and read about the relationship between Panadol, Vaccinations, Glutathione and Autism.

Many Fibromyalgia patients also suffer from IBS (Irritable Bowel Syndrome), CFS (Chronic Fatigue Syndrome), RA (Rheumatoid Arthritis) and SLE or Lupus (Systemic Lupus Erythematosus), but the above treatments can improve all of these conditions.
While these natural alternatives may not work for everyone, nearly all patients report improvement in their condition, and of course, these are all good for weight loss, fighting diabetes, cardiovascular disease, Alzheimer’s disease, better sleep, improved mood, reduced pain, better pain tolerance, building muscle and reduced cancer risk. Many patients are deficient in GH (growth hormone) so high-intensity exercise and weight loss will help by increasing natural production of Growth Hormone.

LeanMachine online supplements

Updated 24th January 2020, Copyright © 1999-2020 Brenton Wight and BJ&HJ Wight trading as Lean Machine abn 55293601285

Ferritin and Iron

What is Ferritin?

Ferritin is an intracellular (inside the cell) protein, in the shape of a hollow sphere. Ferritin stores iron by allowing entry of iron as ferric hydroxide phosphate complexes, and when the body needs iron, releases it as required.
Ferritin is produced by almost every living organism, from bacteria to plants, animals and humans.
In humans, ferritin is a buffer against iron deficiency and iron overload, and is found in most tissues as a cytosolic protein, which means it is inside the cytoplasm, the fluid inside each cell between the outer cell wall and the nucleus (The nucleus contains our DNA).
However, small amounts of ferritin are secreted into the serum (blood) where it works as a carrier of iron.
Plasma ferritin (in the blood) is also an indirect marker of the total amount of iron stored in the body. Serum ferritin levels are used to determine iron deficiency (anaemia) or iron overload.
Ferritin keeps iron in a soluble, non-toxic form. Free ferritin (not combined with iron) is called apoferritin.
Iron is the central atom of haemoglobin, which gives blood it’s red colour. 75% of the body’s iron is stored in haemoglobin, 10 to 20% in the protein ferritin, and the rest in the protein transferrin (the iron transport protein). Small amounts are found in myoglobin, cytochromes, as unbound serum iron and in body tissues.
Excess iron is usually stored in the Liver, Spleen and Bone Marrow, but also in the Pancreas, Joints, Skin, Pituitary, Adrenals, Thyroid, Heart and other organs.
The haemoglobin molecule is a very large molecule, almost identical to the Chlorophyll molecule in plants. Chlorophyll has a central atom of Magnesium, giving grass the green colour. Haemoglobin has Iron as the central atom, giving blood the red colour.
Chlorophyll is commonly best known for “cleansing of the blood”. Best sources are green leafy vegetables and wheatgrass.

Why do we need Iron?

If we have too little iron, we cannot make enough red blood cells, reducing our ability to carry oxygen to all parts of the body.
If we have too much iron, it can damage organs and contribute to cancer, heart disease, the entire cardiovascular system, especially the endothelial cells (the inside lining of all blood vessels), the kidneys and the liver.
Red blood cells are made in the bone marrow, and have a lifespan of around 4 months, when they die (the process called Necrosis).
The body makes around 200 billion new red blood cells every day, along with around 10 billion white cells and about 400 billion platelets every day, and around the same amount die every day.
Dead red blood cells are then broken down by Macrophages (special white blood cells) in the spleen. Some are disposed of in the digestive tract (which makes our poo brown) and parts of other cells are re-used. Haemoglobin is further broken down to salvage the iron, and excess iron is then stored in the liver.
Too much iron in the liver can cause Cirrhosis (Scar tissue replacing healthy cells).
We can have too much iron in some cases because the body does not know how to get rid of excess iron, it only knows how absorb it and to store it (using the transferrin protein).


Healthy red blood cells.

As red blood cells approach death, or are infected with a parasite or bacteria, or have a genetic defect, or are cancerous, the shape, size, smoothness and colour may be different.

How is Iron absorbed?

Iron in food is processed in the high-acid stomach, where it is changed into a form that allows it to be absorbed.
Absorption takes place mainly in the duodenum (part of the small intestine) and also to a lesser extent near the end of the small intestinal tract.
After absorption, iron is transported by the transferrin protein. A healthy body has the ability to absorb more iron when it is required, and absorb less when it is not required.

Haemoglobin, Hemoglobin or Hbg

Haemoglobin is a protein contained in red blood cells.
The job of haemoglobin is to carry oxygen from the lungs to all of the tissue in the body, then return carbon dioxide back to the lungs.
Haemoglobin is composed of four globulin chains (protein molecules) which are connected together, and in adults, haemoglobin contains two alpha-globulin chains and two beta-globulin chains.
In foetuses and infants, haemoglobin contains two alpha chains and two gamma chains, and during growth to an adult, gamma chains are slowly removed, replaced by beta chains to form adult haemoglobin.
Every globulin chain contains the heme molecule as the central structure, and iron is embedded in the heme molecule, essential for the transport of oxygen and carbon dioxide.
Haemoglobin is also essential to help maintain the shape of every red blood cells, which resemble a donut with a dished centre rather than a hole. Any abnormal shape can cause poor flow through blood vessels.

Anaemia, Anemia

Anaemia is a condition where we do not have enough haemoglobin, which is usually, but not always, related to iron deficiency. It can be related to blood loss, from donating blood, from heavy menstrual bleeding, internal bleeding, blood loss from an injury, or insufficient iron in the diet (such as vegans or vegetarians).
IDA (Iron Deficiency Anaemia)
In most cases of anaemia, a blood test will reveal low haemoglobin and low ferritin, a result of iron deficiency, and the doctor will normally recommend iron supplementation or dietary changes or both.
ACD (Anaemia of Chronic Disease)
The body has a safety mechanism against harmful invaders such as cancer or bacteria. When sensing an invader, the body will move all iron it can from red blood cells back to ferritin, because all invaders need iron to thrive, and so does cancer. The body will leave just enough iron in haemoglobin for the cells to survive, but not enough to feed the invader.
We must NEVER take extra iron in cases of Chronic Disease, as we are only feeding the invader and doing more harm to our body.
ACD can be diagnosed by blood tests where we have low haemoglobin, but high ferritin. A C-Reactive Protein test (indicator of inflammation) is advised as well as ferritin if ACD is suspected.
When the disease clears up, the body will automatically return iron levels to normal.
Many doctors do not order ferritin tests when iron is low, resulting in the patient taking iron supplements which can cause damage or even death, so an accurate diagnosis of IDA or ACD is essential.
In some cases, IDA and ACD can occur at the same time, making diagnosis more difficult. One traditional test is Bone Marrow Aspiration with Iron Staining, but the Serum Transferrin Receptor test can help differentiate between IDA and ACD.
The Serum Transferrin Receptor test is significantly less affected by inflammation than the Serum Ferritin test. Results can be high in IDA and usually low in ACD, and the ratio of Serum Transferrin Receptor to the logarithim of Serum Ferritin Concentration is more helpful to distinguish ACD from IDA than is either individual test.
Kidney Damage
If the patient has any kidney damage (sometimes as a result of high iron) then it is possible to have high iron in the body tissues, while regular iron and ferritin tests results are normal or even low. In these cases, a specialist should supervise all testing.

Blood Tests

Normally, the doctor will organise a “Ferritin Study”.
This includes the following tests:

  • Serum Iron – how much iron is circulating in the blood, but this varies considerably and does not always mean a lot without also looking at the TIBC test below.
  • Serum Transferrin – or TIBC (Total Iron Binding Capacity) or Transferrin Saturation. Iron is bound to transferrin (which is produced by the liver), and TIBC is a direct measure of transferrin. Iron overload is indicated with levels over 55% for males and 50% for females. Fasting is preferred for accuracy. Note that inflammation causes reduced transferrin levels
  • Serum Ferritin – Indicates body iron stores. Typical lab results: Normal range 15 to 350 ug/L for men (some labs say up to 500ug/L), 15 – 300 ug/L for women, and varies depending on the lab and the method used, however LeanMachine says that these upper limits are way too high, and that anything over 80 ug/L indicates a possible iron overload condition, and anything below 20 ug/L indicates a possible iron deficiency. A healthy range is 20 to 80 ug/L, and the desirable range is 40 to 60 ug/L, but note that levels over 80 ug/L may be also be caused by liver disease, inflammation or cancer
  • Soluble Transferrin Receptors – Transferrin receptors present on cell surfaces are responsible for internalization of transferrin resulting in intracellular release or iron. With low iron stores, expression of transferrin receptors increases, so the level of soluble transferrin receptors inversely reflects iron stores, and is unaffected by any inflammation, however high soluble transferrin receptors may also mean haemolysis (premature red cell death)
  • A complete blood examination is also required to check Haemoglobin and other factors related to red blood cells, also liver and kidney function. Typical haemoglobin blood results 130g/L to 170g/L for adult males, 120g/L to 150g/L for adult females. For more info on these tests, see my article www.leanmachine.net.au/healthblog/blood-tests-how-to-read-the-results
  • Further tests may include a Liver Biopsy, SQUID (Superconducting Quantum Interference Device), or MRI (Magnetic Resonance Imaging), but these are generally not required except for extreme cases

Note that these are Australian tests. In the USA, the results are in ng/ml (nanograms per millilitre), which is exactly the same as ug/L (micrograms per litre), with upper and lower numbers both divided by 1000, giving the same numerical result.

Types of dietary Iron

There are two main types of dietary iron, heme iron found in meat and other animal products, and non-heme iron found in plant products.
Generally, heme iron is better absorbed than non-heme iron, leaving vegans more at risk for iron insufficiency, however heme iron is also more dangerous for the body in high levels.
A healthy body self-regulates iron levels, by absorbing more iron when we need it, and absorbing less iron when we do not need it, but sometimes this regulation is upset or overloaded.

Factors affecting ferritin/iron levels

Menopausal women often (but not always) have low iron, especially if periods are heavy, while post-menopausal women usually have normal iron.
Pregnancy increases iron requirements, as the body needs to make around 30% more blood to support the developing foetus, requiring 30% more iron. The body will use the body’s stored iron, but if stored iron is insufficient, anaemia will occur. All pregnant women should get their iron and haemoglobin tests done at each trimester, especially if diet or other factors place them at risk.
Blood donors will often have low iron. Red Cross blood donation centres always test haemoglobin levels, and if too low (or even too high), that person cannot donate blood.
For an adult male, the normal range is 125g/L to 185g/L
For an adult woman, the normal range is 115g/L to 165g/L.
For donations of whole blood for males, the acceptable range is 120 to 165g/L for women, and 130 to 185g/L for men.
For donations of plasma and platelets, the acceptable range is 115 to 165g/L for women, and 125 to 185g/L for men.
If below 130 (male) or 120 (female), that person should build up their iron reserves and seek medical advice.
Bleeding in the GI (Gastro-Intestinal) tract can cause low iron, as in any other form of blood loss.
Bleeding because of haemorrhoids or anal fissures, or bleeding from cancer or inflammation in the small intestine, colon or stomach will cause low iron. If stools are dark, or blood in urine, or any unexplained abdomen pain, see your doctor.
Various foods and vitamins can increase or decrease iron absorption – see below.
Foods high in iron are also generally high in Vitamin B12, and both are required for correct ferritin/iron metabolism and healthy Red Blood Cells.
Vegetarians and vegans in particular are susceptible to low iron and B12, as both come mainly from animal products.
As we age, we tend to have reduced stomach acid, resulting in less B12 absorption, and to a lesser extent, reduced absorption of all other minerals, vitamins and other nutrients.
If we take supplemental iron, the body will absorb less iron from the diet.
If we have a low-iron diet, the body responds by absorbing more iron from anything available in food.

Genetics

Sickle cell disease, thalassemia and haemochromatosis can all be inherited, and genetic testing for these and other genes affecting ferritin/iron is available.

Sickle Cell Anaemia

An inherited condition, mainly descendants of African people. A problem with the haemoglobin beta gene causes some red blood cells to become sickle-shaped, especially in hot, dry and intense exercise conditions.
25% of the population in West Africa have the sicklemia trait, also high in South and Central Americans, especially in Panama. Sometimes appears in Mediterranean countries like Italy, Greece, and Spain. Malaria may be a factor, as Indians, Middle Easterners (e.g. Arabs and Iranians), Native Americans, North Africans, and Turks have small but significant cases.
People with Sickle Cell Anemia actually have an advantage in some countries, as they are able to survive better if infected with Malaria. The “sickleing” of the red blood cells is promoted when the Malaria parasite enters, and the body’s own immune system is then able to identify and destroy the cell, along with the malaria parasite.

Thalassemia

An inherited condition, originating in Mediterranean countries, causing weakening and destruction of red blood cells by mutant genes, affecting haemoglobin production. Similar to Sickle-Cell Anaemia.

Haemochromatosis (inherited iron overload disorder)

There is a genetic test for Haemochromatosis.
The test gives results for mutations C282Y and/or H63D of the HFE gene:

  • Mutation not found (No Haemochromatosis)
  • Heterozygous (which means one faulty gene) – Generally no or mild symptoms, bu bay be a “carrier” for children
  • Homozygous (which means two faulty genes)

Children of a Mother and Father who are both carriers of one faulty gene have:

  • 50% risk of inheriting one mutated HFE gene (and becoming a carrier)
  • 25% risk of inheriting both mutated HFE genes (and at risk of excess iron absorption and symptoms of haemochromatosis)
  • 25% risk of inheriting two normal genes, and will not be a carrier

Around 1 in 188 Australians have the HFE genotype C282Y mutation, the most dangerous kind, although 1 in 8 people are carriers for this gene. There are many primary (inherited) types, including:

  • Type 1 – Classical haemochromatosis – Gene Mutation – HFE Genes C282Y and H63D, often with variations. C282Y is more serious.
  • Type 2A – Juvenile haemochromatosis – HJV (Haemojuvelin), also known as RGMc and HFE2 Genes
  • Type 2B – Hepcidin antimicrobial peptide (HAMP) or HFE2B Gene
  • Type 3 – Gene Mutation – Transferrin receptor-2 (TFR2 or HFE3 Genes)
  • Type 4 – African Iron Overload – Ferroportin (SLC11A3/SLC40A1 Genes)
  • Neonatal haemochromatosis – unknown cause
  • Acaeruloplasminaemia (very rare) – Caeruloplasmin
  • Congenital atransferrinaemia (very rare) – Transferrin
  • GRACILE syndrome (very rare) – BCS1L Gene

Also secondary types, which are not inherited, but acquired, especially if the patient has received many repeated blood transfusions.

  • Severe chronic haemolysis – either intravascular haemolysis or ineffective erythropoiesis (haemolysis within the bone marrow)
  • Excess iron from the diet
  • Excess iron from supplements. Any supplements must be kept away from children. This is a common cause of childhood poisoning

Conditions may involve mutant genes inherited from both parents, so patients may have widely differing symptoms.
1 in 700 people with haemochromatosis have no mutation in the HFE gene. This is called Non-HFE haemochromatosis, due to mutations in other genes.

Symptoms of Low Ferritin/Iron

  • Brittle Nails and/or spoon-shaped fingernails
  • Intolerance to Cold
  • Craving or Eating Non-Foods – dirt, hair, coins, etc (Pica)
  • Irritibility, Loss of Concentration, Dizziness
  • Pale appearance, especially membranes – inside of mouth and eyelids
  • Headache
  • Increased infections
  • RLS (Restless Leg Syndrome)
  • Shortness of Breath
  • Weakness
  • Fatigue
  • Loss of Appetite
  • Mouth Ulcers
  • Dry Mouth and/or Sore Tongue
  • Tachycardia (faster than normal heartbeat
  • Arrhythmia (irregular heart beat)
  • Dizziness
  • Drowsiness
  • Loss of Consciousness (Syncope)
  • Enlarged spleen
  • Vitamin B12 deficiency
  • Vitamin D3 deficiency

Symptoms – High Ferritin/Iron

  • Chronic fatigue, tiredness, weakness
  • Low levels of L-Glutathione
  • Low levels of antioxidants
  • Joint pain or aches
  • Abdominal pain
  • Diabetes mellitus (Type 2)
  • Arrhythmia (irregular heart beat)
  • Congestive heart failure
  • Heart attack
  • Changes in skin colour to bronze, ashen-grey or green
  • Period is irregular or stops (women)
  • Low Libido
  • Osteoporosis
  • Osteoarthritis
  • Hair loss
  • Enlarged liver or spleen
  • Impotence (men)
  • Infertility
  • Hypogonadism
  • Hypothyroidism
  • Depression
  • Mood swings
  • Low adrenal function
  • Neurodegenerative disease
  • High blood glucose
  • High liver enzymes – ALT, AST, GGT
  • High serum iron and serum ferritin
  • Higher risk of cancer
  • Weight Loss

How Much Iron do we Need?

Depends on who we are.
For post-menopausal women and healthy men, 8mg daily.
For menopausal women or blood donors, 18mg daily to replace iron in lost blood.
For pregnant women, 27mg daily for rapid growth and development.
Many breakfast cereals give all of menopausal women’s iron requirement, two-thirds the amount required for pregnancy, but double the amount for men and post-menopausal women, not counting intake from other meals.
Typically, there is a total of 3 to 4 grams of iron in the body. A normal diet should give most people enough iron, but vegans and vegetarians and blood donors will oten be lacking. People consuming large quantities of meat, especially liver meats, can reach iron overload withour knowing.

To INCREASE Ferritin/Iron

  • Some breakfast cereals are fortified with extra iron
  • Red meat – beef, lamb, kangaroo and organ meats, especially liver are rich in iron
  • Low alcohol consumption (one drink daily with food) is fine, but overdoing it will cause liver damage
  • Vitamin C (orange juice, fruit, supplements) will increase absorption of iron from food, up to 6 times greater absorption
  • Avoid donating blood too often, or not at all if haemoglobin is less than 130 (men) or 120 (women)
  • Build testosterone, by diet and exercise and/or supplementation to help build new red blood cells
  • If vitamin B-12 and/or Folate is low, supplement or change diet

Iron Overload

This is a dangerous condition, and if iron overload is suspected, a ferritin study is required. See above under “Blood Tests”.

To DECREASE Ferritin/Iron

Blood donation (therapeutic venesection) is usually the best method, and helps save lives of others.
If ineligible for Red Cross donations, private organisations can do this. Usually a ferritin reading of several hundred can be brought down to the normal range after half a dozen or so blood donations.
The only down side is that donations must be spread out over many months to allow the body to build new blood.
Next best option is using IP6 (Inositol Hexaphosphate) which can chelate excess iron from the body.
IP6 can help when the body cannot excrete excess ferritin/iron on it’s own, which can often happen. The body has limited capacity to remove iron, as it tries to always recycle iron.
Also the best alternative when blood donation is impossible, impracticable or ruled out for religious reasons.
IP6 has the added benefit of improving immunity.

More serious cases of iron overload can be treated with:
Deferoxamine (Desferal®) – administered via a needle from a pump attached to the body for 8 to 10 hours a day.
Deferasirox (Exjade®) – a tablet dissolved in a glass of water or juice, taken once a day.
Both methods can have undesirable side-effects, including hearing and vision loss, nausea, diarrhea, rash, kidney or liver injury, so LeanMachine recommends first using blood donation, IP6 and diet measures first.

  • Donate Blood at the Red Cross. Reduces old blood recycling, leading to reduced iron stores which are used up in making new blood. May take several sessions over several months
  • Take IP6 (Inositol Hexaphosphate)
  • Eat cabbage every day (cooked, not raw). No scientific studies have been carried out with cabbage, but plenty of anecdotal evidence suggest it works, possibly by filling up on cabbage, the patient may not feel like red meat…
  • Avoid red meat, and especially liver and other organ meats
  • Drink green tea, black tea, oolong tea or coffee, and/or take a Green Tea Extract. The tannins in tea reduce iron absorption
  • Take Vitamin EVitamin B-6Curcumin
  • Avoid taking too much Vitamin C, as this can increase iron absorption
  • Do not cook in iron pots or pans, even if you have low iron, as metallic iron is bad for the body, regardless of the Ferritin status
  • Avoid alcohol, especially wine with steak
  • Never take iron supplements. If you take a multivitamin, or a “women’s health” or “men’s health” supplement, ensure it has no iron
  • Never drink well water or bore water unless it has been tested free from iron (and other harmful metals)
  • Take Astaxanthin – an extremely powerful antioxidant, 550 times better than Vitamin E. Will not chelate iron, but will help repair the damage

The Low-Iron Diet

Green Tea, black tea, oolong tea and coffee all contain tannins which inhibit iron absorption, so drinking these with a meal can help lower ferritin and iron levels.
Drinking milk with a meal also helps reduce iron absorption because of the calcium in milk that competes with iron for absorption.
Eat an egg every day, as eggs contain a compound that impairs absorption of iron. Avoid red meats, chicken and fish are better choices, much lower in iron than red meat. Better still, go vegetarian or vegan.
Calcium supplements can reduce iron absorption, but can also cause increased plaque in arteries, especially the Calcium Carbonate (ground limestone) used in cheap supplements, so should be avoided.
Breakfast cereals with whole grains contain some iron, but many are fortified with extra iron and should be avoided. Try an apple for breakfast instead and help keep the doctor away.

Disclaimer

LeanMachine is a health researcher, not a doctor, and everyone should consult with their own health professional before taking any product to ensure there is no conflict with existing prescription medication.
LeanMachine has been researching nutrition and health since 2010 and has completed many relevant studies including:
Open2Study, Australia – Food, Nutrition and Your Health
RMIT University, Australia – Foundations of Psychology
Swinburne University of Technology, Australia – Chemistry – Building Blocks of the World
University of Washington, USA – Energy, Diet and Weight
Johns Hopkins Bloomberg School of Public Health, USA – Health Issues for Aging Populations
Johns Hopkins Bloomberg School of Public Health, USA – International Nutrition
Johns Hopkins Bloomberg School of Public Health, USA – Methods in Biostatistics I
Johns Hopkins Bloomberg School of Public Health, USA – Methods in Biostatistics II
Johns Hopkins Bloomberg School of Public Health, USA – Principles of Human Nutrition
TUFTS University, USA – Nutrition and Medicine
TUFTS University, USA – Lipids/Cardiovascular Disease I and Lipids/Cardiovascular Disease II
Technical Learning College, USA – Western Herbology, Identification, Formulas
Bath University, England – Inside Cancer
WebMD Education – The Link Between Stroke and Atrial Fibrillation
WebMD Education – High Potassium: Causes and Reasons to Treat
Leiden University Medical Center, Netherlands – Anatomy of the Abdomen and Pelvis
MIT (Massachusetts Institute of Technology) – A Clinical Approach to the Human Brain
LeanMachine has now examined thousands of studies, journals and reports related to health and nutrition and this research is ongoing.

Updated 25th May 2020, Copyright © 1999-2020 Brenton Wight and BJ & HJ Wight trading as Lean Machine abn 55293601285

Ginger Improves Symptoms of Ulcerative Colitis, Enhances Quality of Life

© 18th December 2019 GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here www.greenmedinfo.com/greenmed/newsletter
Reproduced from original article:
www.greenmedinfo.com/blog/ginger-improves-symptoms-ulcerative-colitis-enhances-quality-life

Posted on: Wednesday, December 18th 2019 at 1:30 pm

Bowel and digestive problems like ulcerative colitis can be among the most discomforting and disruptive affronts to a person’s lifestyle and overall well-being. What if adding a healthy dose of ginger to your diet could prevent indigestion, inflamed insides and even protect you from colon and rectal cancers? The evidence says, it can

Ulcerative colitis (UC) is a chronic inflammatory bowel condition affecting more than 750,000 people in North America.[i] The disorder, a form of inflammatory bowel disease (IBD), causes open sores or ulcers to develop in the lining of the large intestine. Unlike Crohn’s, another form of IBD that can affect the entire digestive tract, colitis affects only the inner surface of the large intestine.[ii]

UC is considered to be incurable, however patients must seek to manage their symptoms. Untreated UC can cause long-term damage to the colon and increases risks of colon and anal cancers.[iii] Fortunately, natural options such as ginger may help.

Ginger: An Antidote to Oxidative Stress

Oxidative stress reflects an imbalance between the body’s antioxidant defense mechanisms and the activity of free radicals, errant electrons that are known to cause damage to healthy cells and tissues.[iv] Oxidative stress is believed to play an essential role in the initiation and severity of ulcerative colitis (UC).

Researchers at Shahid Beheshti University of Medical Sciences, Tehran, Iran, explored the use of ginger (scientific name: Zingiber officinale), a well-known antioxidant plant root, on the quality of life, disease activity and oxidative stress of patients with UC.

Published in the journal Complementary Therapies in Medicine,[v] researchers assembled 46 patients with active cases of mild to moderate UC. Patients were randomly assigned to receive either ginger or a placebo, with ginger group subjects consuming 2,000 milligrams (mg) per day of dried ginger powder in four capsules, and the placebo group receiving similar, non-active capsules.

The trial was conducted for a period of 12 weeks, with measurements taken before, at midpoint, and at the end of intervention, using valid and reliable quality of life and disease activity questionnaires and blood sampling.

Ginger Improves Quality of Life for Ulcerative Colitis Patients

Results of this study were highly favorable towards the use of ginger in the treatment of ulcerative colitis. After just six weeks of supplementation, blood tests showed that levels of malondialdehyde, an organic compound that is a marker of oxidative stress, were significantly reduced. After 12 weeks, this marker was barely detectable.

Scores for severity of disease activity were also significantly improved after 12 weeks of ginger supplementation versus placebo. Perhaps the most encouraging marker of success for ginger supplementation is that it significantly increased patients’ quality of life at the 12-week mark.

Researchers concluded that ginger supplementation can improve outcomes for patients with UC. They requested further clinical trials utilizing different dosages and duration of supplementation to obtain firm conclusion of ginger’s efficacy when treating UC.

Ginger: A Disease-Prevention Powerhouse

GreenMedinfo has more than 300 scientific abstracts on the powerful, disease-prohibiting effects of ginger, one of the world’s most powerful natural-healing substances. It’s undoubtedly one of the best plants to include in your herbal apothecary, having proven to be effective against the most prevalent diseases of the modern era, such as heart disease, stroke, cancer, and diabetes.

Ginger’s protective effect against cancer may be among it’s most potent attributes. Zerumbone, one of ginger’s isolated active compounds, has been shown to inhibit colon and lung carcinogenesis in mice. Another active compound that has been isolated in ginger — zingerone — has “massive pharmacological properties” and has been validated in studies as a promising treatment against colorectal cancer.[vi]

Ulcerative Colitis Has Many Causes and Symptoms

While the exact cause of ulcerative colitis (UC) is unclear, factors such as poor dietary habits and periods of extreme stress are often predicators. Characterized as an overactive immune response, the body may be reacting to food sensitivities, imbalanced bacteria in the gut or exposure to viruses that cause inflammation.

Individuals with at least one diagnosed autoimmune condition may be at higher risk for developing UC. Signs that an individual might have ulcerative colitis include:

  • Persistent changes in bowel habits
  • Frequent or severe abdominal pain
  • Blood in the stool
  • Recurring or urgent diarrhea
  • A low-grade fever lasting more than two days

Ulcerative colitis can cause significant discomfort. Patients typically experience frequent diarrhea, which can be accompanied by mucus and blood. If the patient develops chronic bleeding, anemia (low red blood cell count) can develop along with accompanying chronic fatigue.

Some patients experience an inability to eat or move their bowels normally, which can be accompanied by severe weight loss and dehydration, further disrupting normal life activities.

Ulcerative Colitis Is a Life-Changing Diagnosis

Ulcerative colitis is diagnosed via an array of tests, some or all of which may be ordered by your doctor. These tests include stool samples, blood tests to detect anemia, X-rays and CT scans. In addition to these tests, when a patient complains of abdominal pain or “bathroom issues,” the doctor may order imaging to examine the lining of the digestive tract.

The most common imaging procedures used to diagnose IBD are endoscopy and colonoscopy. Endoscopy can be done on the upper and lower digestive tract, with upper endoscopy performed by inserting a thin, flexible camera called an endoscope down the throat. Lower endoscopy, or colonoscopy, is performed by inserting the endoscope into the rectum to explore the lower intestine. Both procedures are done under light sedation.

Patients who undergo colonoscopies will be checked for polyps, small growths inside the colon or rectum. If polyps are detected, a biopsy is typically performed to detect if cancer cells are present.[vii] By ruling out colon cancer, a more definitive diagnosis of UC can be made.

Ulcerative Colitis Can Lead to Severe Bowel Disease

UC can present across the spectrum of severity, from infrequent, acute episodes to a debilitating chronic condition. What is common to all sufferers is the potential for severe complications if left untreated and unmanaged. Possible complications of ulcerative colitis include:

  • Serious bleeding and anemia
  • Holes in the colon
  • Severe dehydration
  • Bone loss
  • Inflammation of skin, joints and eyes
  • Increased risk of bowel cancers
  • Rapid swelling of the colon (toxic megacolon)
  • Increased risk of blood clots[viii]

Don’t ignore the warning signs: consult your doctor if you experience symptoms of colitis. While UC is rarely fatal, it is important to begin treatment as soon as possible upon diagnosis to prevent serious, potentially life-threatening complications from developing.

With Proper Treatment, Ulcerative Colitis Is a Manageable Condition

Much like the disease symptoms that can present across a spectrum of severity, treatments for UC range widely in scope and intensity. At early stages of UC, lifestyle changes such as dietary modification and proper stress management may prove sufficient to remediate the condition.

UC patients are frequently prescribed immunosuppressant drugs in an attempt to cease the abnormal immune system response that is believed to be attacking the colon from within.

In more severe and persistent cases of UC, treatment options can escalate to include full or partial removal of the lower colon (a colectomy), inclusive of the rectum in a proctocolectomy. In such cases, patients may require an ostomy, a surgery in which a new body opening is created and attached to a stoma and collection bag, effectively rerouting bodily waste.[ix]

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References

[i] U.S. National Library of Medicine, Genetics Home Reference, Ulcerative Colitis.

[ii] U.S. National Library of Medicine, Genetics Home Reference, Ulcerative Colitis.

[iii] Mayo Clinic, Patient Care & Health Information, Diseases & Conditions, Ulcerative Colitis.

[iv] Metabolism. 2000 Feb;49(2 Suppl 1):3-8. Betteridge DJ. PMID: 10693912. DOI: 10.1016/s0026-0495(00)80077-3.

[v] Complementary Therapies in Medicine, Volume 43, April 2019, Pages 1-6. PMID: 30935515. DOI: 10.1016/j.ctim.2018.12.021.

[vi] Environ Toxicol. 2019 May;34(5):610-625. Ganaie MA, Al Saeedan A, Madhkali H, Jan BL, Khatlani T, Sheikh IA, Rehman MU, Wani K. PMID: 30720227. doi: 10.1002/tox.22727.

[vii] Cancer Treatment Centers of America, Colonoscopy and endoscopic ultrasound, Colonoscopy and endoscopic procedures.

[viii] Mayo Clinic, Patient Care & Health Information, Diseases & Conditions, Ulcerative Colitis.

[ix] United Ostomy Association of America, What Is an Ostomy?

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.